DeformCL: Learning Deformable Centerline Representation for Vessel Extraction in 3D Medical Image

In the field of 3D medical imaging, accurately extracting and representing the blood vessels with curvilinear structures holds paramount importance for clinical diagnosis. Previous methods have commonly relied on discrete representation like mask, often resulting in local fractures or scattered fragments due to the inherent limitations of the per-pixel classification paradigm. In this work, we introduce DeformCL, a new continuous representation based on Deformable Centerlines, where centerline points act as nodes connected by edges that capture spatial relationships. Compared with previous representations, DeformCL offers three key advantages: natural connectivity, noise robustness, and interaction facility. We present a comprehensive training pipeline structured in a cascaded manner to fully exploit these favorable properties of DeformCL. Extensive experiments on four 3D vessel segmentation datasets demonstrate the effectiveness and superiority of our method. Furthermore, the visualization of curved planar reformation images validates the clinical significance of the proposed framework. We release the code in https://github.com/barry664/DeformCL

Infi-MMR: Curriculum-based Unlocking Multimodal Reasoning via Phased Reinforcement Learning in Multimodal Small Language Models

Recent advancements in large language models (LLMs) have demonstrated substantial progress in reasoning capabilities, such as DeepSeek-R1, which leverages rule-based reinforcement learning to enhance logical reasoning significantly. However, extending these achievements to multimodal large language models (MLLMs) presents critical challenges, which are frequently more pronounced for Multimodal Small Language Models (MSLMs) given their typically weaker foundational reasoning abilities: (1) the scarcity of high-quality multimodal reasoning datasets, (2) the degradation of reasoning capabilities due to the integration of visual processing, and (3) the risk that direct application of reinforcement learning may produce complex yet incorrect reasoning processes. To address these challenges, we design a novel framework Infi-MMR to systematically unlock the reasoning potential of MSLMs through a curriculum of three carefully structured phases and propose our multimodal reasoning model Infi-MMR-3B. The first phase, Foundational Reasoning Activation, leverages high-quality textual reasoning datasets to activate and strengthen the model's logical reasoning capabilities. The second phase, Cross-Modal Reasoning Adaptation, utilizes caption-augmented multimodal data to facilitate the progressive transfer of reasoning skills to multimodal contexts. The third phase, Multimodal Reasoning Enhancement, employs curated, caption-free multimodal data to mitigate linguistic biases and promote robust cross-modal reasoning. Infi-MMR-3B achieves both state-of-the-art multimodal math reasoning ability (43.68% on MathVerse testmini, 27.04% on MathVision test, and 21.33% on OlympiadBench) and general reasoning ability (67.2% on MathVista testmini).

Interpreting Chest X-rays Like a Radiologist: A Benchmark with Clinical Reasoning

Artificial intelligence (AI)-based chest X-ray (CXR) interpretation assistants have demonstrated significant progress and are increasingly being applied in clinical settings. However, contemporary medical AI models often adhere to a simplistic input-to-output paradigm, directly processing an image and an instruction to generate a result, where the instructions may be integral to the model's architecture. This approach overlooks the modeling of the inherent diagnostic reasoning in chest X-ray interpretation. Such reasoning is typically sequential, where each interpretive stage considers the images, the current task, and the contextual information from previous stages. This oversight leads to several shortcomings, including misalignment with clinical scenarios, contextless reasoning, and untraceable errors. To fill this gap, we construct CXRTrek, a new multi-stage visual question answering (VQA) dataset for CXR interpretation. The dataset is designed to explicitly simulate the diagnostic reasoning process employed by radiologists in real-world clinical settings for the first time. CXRTrek covers 8 sequential diagnostic stages, comprising 428,966 samples and over 11 million question-answer (Q&A) pairs, with an average of 26.29 Q&A pairs per sample. Building on the CXRTrek dataset, we propose a new vision-language large model (VLLM), CXRTrekNet, specifically designed to incorporate the clinical reasoning flow into the VLLM framework. CXRTrekNet effectively models the dependencies between diagnostic stages and captures reasoning patterns within the radiological context. Trained on our dataset, the model consistently outperforms existing medical VLLMs on the CXRTrek benchmarks and demonstrates superior generalization across multiple tasks on five diverse external datasets. The dataset and model can be found in our repository (https://github.com/guanjinquan/CXRTrek).

T2I-ConBench: Text-to-Image Benchmark for Continual Post-training

Continual post-training adapts a single text-to-image diffusion model to learn new tasks without incurring the cost of separate models, but naive post-training causes forgetting of pretrained knowledge and undermines zero-shot compositionality. We observe that the absence of a standardized evaluation protocol hampers related research for continual post-training. To address this, we introduce T2I-ConBench, a unified benchmark for continual post-training of text-to-image models. T2I-ConBench focuses on two practical scenarios, item customization and domain enhancement, and analyzes four dimensions: (1) retention of generality, (2) target-task performance, (3) catastrophic forgetting, and (4) cross-task generalization. It combines automated metrics, human-preference modeling, and vision-language QA for comprehensive assessment. We benchmark ten representative methods across three realistic task sequences and find that no approach excels on all fronts. Even joint "oracle" training does not succeed for every task, and cross-task generalization remains unsolved. We release all datasets, code, and evaluation tools to accelerate research in continual post-training for text-to-image models.

UrbanMind: Urban Dynamics Prediction with Multifaceted Spatial-Temporal Large Language Models

Understanding and predicting urban dynamics is crucial for managing transportation systems, optimizing urban planning, and enhancing public services. While neural network-based approaches have achieved success, they often rely on task-specific architectures and large volumes of data, limiting their ability to generalize across diverse urban scenarios. Meanwhile, Large Language Models (LLMs) offer strong reasoning and generalization capabilities, yet their application to spatial-temporal urban dynamics remains underexplored. Existing LLM-based methods struggle to effectively integrate multifaceted spatial-temporal data and fail to address distributional shifts between training and testing data, limiting their predictive reliability in real-world applications. To bridge this gap, we propose UrbanMind, a novel spatial-temporal LLM framework for multifaceted urban dynamics prediction that ensures both accurate forecasting and robust generalization. At its core, UrbanMind introduces Muffin-MAE, a multifaceted fusion masked autoencoder with specialized masking strategies that capture intricate spatial-temporal dependencies and intercorrelations among multifaceted urban dynamics. Additionally, we design a semantic-aware prompting and fine-tuning strategy that encodes spatial-temporal contextual details into prompts, enhancing LLMs' ability to reason over spatial-temporal patterns. To further improve generalization, we introduce a test time adaptation mechanism with a test data reconstructor, enabling UrbanMind to dynamically adjust to unseen test data by reconstructing LLM-generated embeddings. Extensive experiments on real-world urban datasets across multiple cities demonstrate that UrbanMind consistently outperforms state-of-the-art baselines, achieving high accuracy and robust generalization, even in zero-shot settings.

InfiGUI-R1: Advancing Multimodal GUI Agents from Reactive Actors to Deliberative Reasoners

Multimodal Large Language Models (MLLMs) have powered Graphical User Interface (GUI) Agents, showing promise in automating tasks on computing devices. Recent works have begun exploring reasoning in GUI tasks with encouraging results. However, many current approaches rely on manually designed reasoning templates, which may result in reasoning that is not sufficiently robust and adaptive for complex GUI environments. Meanwhile, some existing agents continue to operate as Reactive Actors, relying primarily on implicit reasoning that may lack sufficient depth for GUI tasks demanding planning and error recovery. We argue that advancing these agents requires a shift from reactive acting towards acting based on deliberate reasoning. To facilitate this transformation, we introduce InfiGUI-R1, an MLLM-based GUI agent developed through our Actor2Reasoner framework, a reasoning-centric, two-stage training approach designed to progressively evolve agents from Reactive Actors to Deliberative Reasoners. The first stage, Reasoning Injection, focuses on establishing a basic reasoner. We employ Spatial Reasoning Distillation to transfer cross-modal spatial reasoning capabilities from teacher models to MLLMs through trajectories with explicit reasoning steps, enabling models to integrate GUI visual-spatial information with logical reasoning before action generation. The second stage, Deliberation Enhancement, refines the basic reasoner into a deliberative one using Reinforcement Learning. This stage introduces two approaches: Sub-goal Guidance, which rewards models for generating accurate intermediate sub-goals, and Error Recovery Scenario Construction, which creates failure-and-recovery training scenarios from identified prone-to-error steps. Experimental results show InfiGUI-R1 achieves strong performance in GUI grounding and trajectory tasks. Resources at https://github.com/Reallm-Labs/InfiGUI-R1.

Negate or Embrace: On How Misalignment Shapes Multimodal Representation Learning

Multimodal representation learning, exemplified by multimodal contrastive learning (MMCL) using image-text pairs, aims to learn powerful representations by aligning cues across modalities. This approach relies on the core assumption that the exemplar image-text pairs constitute two representations of an identical concept. However, recent research has revealed that real-world datasets often exhibit misalignment. There are two distinct viewpoints on how to address this issue: one suggests mitigating the misalignment, and the other leveraging it. We seek here to reconcile these seemingly opposing perspectives, and to provide a practical guide for practitioners. Using latent variable models we thus formalize misalignment by introducing two specific mechanisms: selection bias, where some semantic variables are missing, and perturbation bias, where semantic variables are distorted -- both affecting latent variables shared across modalities. Our theoretical analysis demonstrates that, under mild assumptions, the representations learned by MMCL capture exactly the information related to the subset of the semantic variables invariant to selection and perturbation biases. This provides a unified perspective for understanding misalignment. Based on this, we further offer actionable insights into how misalignment should inform the design of real-world ML systems. We validate our theoretical findings through extensive empirical studies on both synthetic data and real image-text datasets, shedding light on the nuanced impact of misalignment on multimodal representation learning.

Analytic DAG Constraints for Differentiable DAG Learning

Recovering the underlying Directed Acyclic Graph (DAG) structures from observational data presents a formidable challenge, partly due to the combinatorial nature of the DAG-constrained optimization problem. Recently, researchers have identified gradient vanishing as one of the primary obstacles in differentiable DAG learning and have proposed several DAG constraints to mitigate this issue. By developing the necessary theory to establish a connection between analytic functions and DAG constraints, we demonstrate that analytic functions from the set $\{f(x) = c_0 + \sum_{i=1}^{\infty}c_ix^i | \forall i > 0, c_i > 0; r = \lim_{i\rightarrow \infty}c_{i}/c_{i+1} > 0\}$ can be employed to formulate effective DAG constraints. Furthermore, we establish that this set of functions is closed under several functional operators, including differentiation, summation, and multiplication. Consequently, these operators can be leveraged to create novel DAG constraints based on existing ones. Using these properties, we design a series of DAG constraints and develop an efficient algorithm to evaluate them. Experiments in various settings demonstrate that our DAG constraints outperform previous state-of-the-art comparators. Our implementation is available at https://github.com/zzhang1987/AnalyticDAGLearning.

H2ST: Hierarchical Two-Sample Tests for Continual Out-of-Distribution Detection

Task Incremental Learning (TIL) is a specialized form of Continual Learning (CL) in which a model incrementally learns from non-stationary data streams. Existing TIL methodologies operate under the closed-world assumption, presuming that incoming data remains in-distribution (ID). However, in an open-world setting, incoming samples may originate from out-of-distribution (OOD) sources, with their task identities inherently unknown. Continually detecting OOD samples presents several challenges for current OOD detection methods: reliance on model outputs leads to excessive dependence on model performance, selecting suitable thresholds is difficult, hindering real-world deployment, and binary ID/OOD classification fails to provide task-level identification. To address these issues, we propose a novel continual OOD detection method called the Hierarchical Two-sample Tests (H2ST). H2ST eliminates the need for threshold selection through hypothesis testing and utilizes feature maps to better exploit model capabilities without excessive dependence on model performance. The proposed hierarchical architecture enables task-level detection with superior performance and lower overhead compared to non-hierarchical classifier two-sample tests. Extensive experiments and analysis validate the effectiveness of H2ST in open-world TIL scenarios and its superiority to the existing methods. Code is available at \href{https://github.com/YuhangLiuu/H2ST}{https://github.com/YuhangLiuu/H2ST}.

Empirical Privacy Variance

We propose the notion of empirical privacy variance and study it in the context of differentially private fine-tuning of language models. Specifically, we show that models calibrated to the same $(\varepsilon, \delta)$-DP guarantee using DP-SGD with different hyperparameter configurations can exhibit significant variations in empirical privacy, which we quantify through the lens of memorization. We investigate the generality of this phenomenon across multiple dimensions and discuss why it is surprising and relevant. Through regression analysis, we examine how individual and composite hyperparameters influence empirical privacy. The results reveal a no-free-lunch trade-off: existing practices of hyperparameter tuning in DP-SGD, which focus on optimizing utility under a fixed privacy budget, often come at the expense of empirical privacy. To address this, we propose refined heuristics for hyperparameter selection that explicitly account for empirical privacy, showing that they are both precise and practically useful. Finally, we take preliminary steps to understand empirical privacy variance. We propose two hypotheses, identify limitations in existing techniques like privacy auditing, and outline open questions for future research.