Towards Prospective Medical Image Reconstruction via Knowledge-Informed Dynamic Optimal Transport

Medical image reconstruction from measurement data is a vital but challenging inverse problem. Deep learning approaches have achieved promising results, but often requires paired measurement and high-quality images, which is typically simulated through a forward model, i.e., retrospective reconstruction. However, training on simulated pairs commonly leads to performance degradation on real prospective data due to the retrospective-to-prospective gap caused by incomplete imaging knowledge in simulation. To address this challenge, this paper introduces imaging Knowledge-Informed Dynamic Optimal Transport (KIDOT), a novel dynamic optimal transport framework with optimality in the sense of preserving consistency with imaging physics in transport, that conceptualizes reconstruction as finding a dynamic transport path. KIDOT learns from unpaired data by modeling reconstruction as a continuous evolution path from measurements to images, guided by an imaging knowledge-informed cost function and transport equation. This dynamic and knowledge-aware approach enhances robustness and better leverages unpaired data while respecting acquisition physics. Theoretically, we demonstrate that KIDOT naturally generalizes dynamic optimal transport, ensuring its mathematical rationale and solution existence. Extensive experiments on MRI and CT reconstruction demonstrate KIDOT's superior performance.

A Preliminary Study for GPT-4o on Image Restoration

OpenAI's GPT-4o model, integrating multi-modal inputs and outputs within an autoregressive architecture, has demonstrated unprecedented performance in image generation. In this work, we investigate its potential impact on the image restoration community. We present the first systematic evaluation of GPT-4o across diverse restoration tasks. Our experiments reveal that, although restoration outputs from GPT-4o are visually appealing, they often suffer from pixel-level structural fidelity when compared to ground-truth images. Common issues are variations in image proportions, shifts in object positions and quantities, and changes in viewpoint.To address it, taking image dehazing, derainning, and low-light enhancement as representative case studies, we show that GPT-4o's outputs can serve as powerful visual priors, substantially enhancing the performance of existing dehazing networks. It offers practical guidelines and a baseline framework to facilitate the integration of GPT-4o into future image restoration pipelines. We hope the study on GPT-4o image restoration will accelerate innovation in the broader field of image generation areas. To support further research, we will release GPT-4o-restored images from over 10 widely used image restoration datasets.

Cross-organ all-in-one parallel compressed sensing magnetic resonance imaging

Recent advances in deep learning-based parallel compressed sensing magnetic resonance imaging (p-CSMRI) have significantly improved reconstruction quality. However, current p-CSMRI methods often require training separate deep neural network (DNN) for each organ due to anatomical variations, creating a barrier to developing generalized medical image reconstruction systems. To address this, we propose CAPNet (cross-organ all-in-one deep unfolding p-CSMRI network), a unified framework that implements a p-CSMRI iterative algorithm via three specialized modules: auxiliary variable module, prior module, and data consistency module. Recognizing that p-CSMRI systems often employ varying sampling ratios for different organs, resulting in organ-specific artifact patterns, we introduce an artifact generation submodule, which extracts and integrates artifact features into the data consistency module to enhance the discriminative capability of the overall network. For the prior module, we design an organ structure-prompt generation submodule that leverages structural features extracted from the segment anything model (SAM) to create cross-organ prompts. These prompts are strategically incorporated into the prior module through an organ structure-aware Mamba submodule. Comprehensive evaluations on a cross-organ dataset confirm that CAPNet achieves state-of-the-art reconstruction performance across multiple anatomical structures using a single unified model. Our code will be published at https://github.com/shibaoshun/CAPNet.

ImPart: Importance-Aware Delta-Sparsification for Improved Model Compression and Merging in LLMs

With the proliferation of task-specific large language models, delta compression has emerged as a method to mitigate the resource challenges of deploying numerous such models by effectively compressing the delta model parameters. Previous delta-sparsification methods either remove parameters randomly or truncate singular vectors directly after singular value decomposition (SVD). However, these methods either disregard parameter importance entirely or evaluate it with too coarse a granularity. In this work, we introduce ImPart, a novel importance-aware delta sparsification approach. Leveraging SVD, it dynamically adjusts sparsity ratios of different singular vectors based on their importance, effectively retaining crucial task-specific knowledge even at high sparsity ratios. Experiments show that ImPart achieves state-of-the-art delta sparsification performance, demonstrating $2\times$ higher compression ratio than baselines at the same performance level. When integrated with existing methods, ImPart sets a new state-of-the-art on delta quantization and model merging.

Growing a Twig to Accelerate Large Vision-Language Models

Large vision-language models (VLMs) have demonstrated remarkable capabilities in open-world multimodal understanding, yet their high computational overheads pose great challenges for practical deployment. Some recent works have proposed methods to accelerate VLMs by pruning redundant visual tokens guided by the attention maps of VLM's early layers. Despite the success of these token pruning methods, they still suffer from two major shortcomings: (i) considerable accuracy drop due to insensitive attention signals in early layers, and (ii) limited speedup when generating long responses (e.g., 30 tokens). To address the limitations above, we present TwigVLM -- a simple and general architecture by growing a lightweight twig upon an early layer of the base VLM. Compared with most existing VLM acceleration methods purely based on visual token pruning, our TwigVLM not only achieves better accuracy retention by employing a twig-guided token pruning (TTP) strategy, but also yields higher generation speed by utilizing a self-speculative decoding (SSD) strategy. Taking LLaVA-1.5-7B as the base VLM, experimental results show that TwigVLM preserves 96% of the original performance after pruning 88.9% of visual tokens and achieves 154% speedup in generating long responses, delivering significantly better performance in terms of both accuracy and speed over the state-of-the-art VLM acceleration methods. Code will be made publicly available.

ProBench: Judging Multimodal Foundation Models on Open-ended Multi-domain Expert Tasks

Solving expert-level multimodal tasks is a key milestone towards general intelligence. As the capabilities of multimodal large language models (MLLMs) continue to improve, evaluation of such advanced multimodal intelligence becomes necessary yet challenging. In this work, we introduce ProBench, a benchmark of open-ended user queries that require professional expertise and advanced reasoning. ProBench consists of 4,000 high-quality samples independently submitted by professionals based on their daily productivity demands. It spans across 10 fields and 56 sub-fields, including science, arts, humanities, coding, mathematics, and creative writing. Experimentally, we evaluate and compare 24 latest models using MLLM-as-a-Judge. Our results reveal that although the best open-source models rival the proprietary ones, ProBench presents significant challenges in visual perception, textual understanding, domain knowledge and advanced reasoning, thus providing valuable directions for future multimodal AI research efforts.

Spatial Transcriptomics Analysis of Spatially Dense Gene Expression Prediction

Spatial transcriptomics (ST) measures gene expression at fine-grained spatial resolution, offering insights into tissue molecular landscapes. Previous methods for spatial gene expression prediction usually crop spots of interest from pathology tissue slide images, and learn a model that maps each spot to a single gene expression profile. However, it fundamentally loses spatial resolution of gene expression: 1) each spot often contains multiple cells with distinct gene expression; 2) spots are cropped at fixed resolutions, limiting the ability to predict gene expression at varying spatial scales. To address these limitations, this paper presents PixNet, a dense prediction network capable of predicting spatially resolved gene expression across spots of varying sizes and scales directly from pathology images. Different from previous methods that map individual spots to gene expression values, we generate a dense continuous gene expression map from the pathology image, and aggregate values within spots of interest to predict the gene expression. Our PixNet outperforms state-of-the-art methods on 3 common ST datasets, while showing superior performance in predicting gene expression across multiple spatial scales. The source code will be publicly available.

A space-decoupling framework for optimization on bounded-rank matrices with orthogonally invariant constraints

Imposing additional constraints on low-rank optimization has garnered growing interest. However, the geometry of coupled constraints hampers the well-developed low-rank structure and makes the problem intricate. To this end, we propose a space-decoupling framework for optimization on bounded-rank matrices with orthogonally invariant constraints. The ``space-decoupling" is reflected in several ways. We show that the tangent cone of coupled constraints is the intersection of tangent cones of each constraint. Moreover, we decouple the intertwined bounded-rank and orthogonally invariant constraints into two spaces, leading to optimization on a smooth manifold. Implementing Riemannian algorithms on this manifold is painless as long as the geometry of additional constraints is known. In addition, we unveil the equivalence between the reformulated problem and the original problem. Numerical experiments on real-world applications -- spherical data fitting, graph similarity measuring, low-rank SDP, model reduction of Markov processes, reinforcement learning, and deep learning -- validate the superiority of the proposed framework.

High Resolution Tree Height Mapping of the Amazon Forest using Planet NICFI Images and LiDAR-Informed U-Net Model

Tree canopy height is one of the most important indicators of forest biomass, productivity, and ecosystem structure, but it is challenging to measure accurately from the ground and from space. Here, we used a U-Net model adapted for regression to map the mean tree canopy height in the Amazon forest from Planet NICFI images at ~4.78 m spatial resolution for the period 2020-2024. The U-Net model was trained using canopy height models computed from aerial LiDAR data as a reference, along with their corresponding Planet NICFI images. Predictions of tree heights on the validation sample exhibited a mean error of 3.68 m and showed relatively low systematic bias across the entire range of tree heights present in the Amazon forest. Our model successfully estimated canopy heights up to 40-50 m without much saturation, outperforming existing canopy height products from global models in this region. We determined that the Amazon forest has an average canopy height of ~22 m. Events such as logging or deforestation could be detected from changes in tree height, and encouraging results were obtained to monitor the height of regenerating forests. These findings demonstrate the potential for large-scale mapping and monitoring of tree height for old and regenerating Amazon forests using Planet NICFI imagery.

Exploring Temporal Event Cues for Dense Video Captioning in Cyclic Co-learning

Dense video captioning aims to detect and describe all events in untrimmed videos. This paper presents a dense video captioning network called Multi-Concept Cyclic Learning (MCCL), which aims to: (1) detect multiple concepts at the frame level, using these concepts to enhance video features and provide temporal event cues; and (2) design cyclic co-learning between the generator and the localizer within the captioning network to promote semantic perception and event localization. Specifically, we perform weakly supervised concept detection for each frame, and the detected concept embeddings are integrated into the video features to provide event cues. Additionally, video-level concept contrastive learning is introduced to obtain more discriminative concept embeddings. In the captioning network, we establish a cyclic co-learning strategy where the generator guides the localizer for event localization through semantic matching, while the localizer enhances the generator's event semantic perception through location matching, making semantic perception and event localization mutually beneficial. MCCL achieves state-of-the-art performance on the ActivityNet Captions and YouCook2 datasets. Extensive experiments demonstrate its effectiveness and interpretability.