Differentiable Neural Architecture Search (DNAS) has demonstrated great success in designing state-of-the-art, efficient neural networks. However, DARTS-based DNAS's search space is small when compared to other search methods', since all candidate network layers must be explicitly instantiated in memory. To address this bottleneck, we propose a memory and computationally efficient DNAS variant: DMaskingNAS. This algorithm expands the search space by up to $10^{14}\times$ over conventional DNAS, supporting searches over spatial and channel dimensions that are otherwise prohibitively expensive: input resolution and number of filters. We propose a masking mechanism for feature map reuse, so that memory and computational costs stay nearly constant as the search space expands. Furthermore, we employ effective shape propagation to maximize per-FLOP or per-parameter accuracy. The searched FBNetV2s yield state-of-the-art performance when compared with all previous architectures. With up to 421$\times$ less search cost, DMaskingNAS finds models with 0.9% higher accuracy, 15% fewer FLOPs than MobileNetV3-Small; and with similar accuracy but 20% fewer FLOPs than Efficient-B0. Furthermore, our FBNetV2 outperforms MobileNetV3 by 2.6% in accuracy, with equivalent model size. FBNetV2 models are open-sourced at https://github.com/facebookresearch/mobile-vision.
Cervical cancer is the second most prevalent cancer affecting women today. As the early detection of cervical carcinoma relies heavily upon screening and pre-clinical testing, digital cervicography has great potential as a primary or auxiliary screening tool, especially in low-resource regions due to its low cost and easy access. Although an automated cervical dysplasia detection system has been desirable, traditional fully-supervised training of such systems requires large amounts of annotated data which are often labor-intensive to collect. To alleviate the need for much manual annotation, we propose a novel graph convolutional network (GCN) based semi-supervised classification model that can be trained with fewer annotations. In existing GCNs, graphs are constructed with fixed features and can not be updated during the learning process. This limits their ability to exploit new features learned during graph convolution. In this paper, we propose a novel and more flexible GCN model with a feature encoder that adaptively updates the adjacency matrix during learning and demonstrate that this model design leads to improved performance. Our experimental results on a cervical dysplasia classification dataset show that the proposed framework outperforms previous methods under a semi-supervised setting, especially when the labeled samples are scarce.
Uterine cancer, also known as endometrial cancer, can seriously affect the female reproductive organs, and histopathological image analysis is the gold standard for diagnosing endometrial cancer. However, due to the limited capability of modeling the complicated relationships between histopathological images and their interpretations, these computer-aided diagnosis (CADx) approaches based on traditional machine learning algorithms often failed to achieve satisfying results. In this study, we developed a CADx approach using a convolutional neural network (CNN) and attention mechanisms, called HIENet. Because HIENet used the attention mechanisms and feature map visualization techniques, it can provide pathologists better interpretability of diagnoses by highlighting the histopathological correlations of local (pixel-level) image features to morphological characteristics of endometrial tissue. In the ten-fold cross-validation process, the CADx approach, HIENet, achieved a 76.91 $\pm$ 1.17% (mean $\pm$ s. d.) classification accuracy for four classes of endometrial tissue, namely normal endometrium, endometrial polyp, endometrial hyperplasia, and endometrial adenocarcinoma. Also, HIENet achieved an area-under-the-curve (AUC) of 0.9579 $\pm$ 0.0103 with an 81.04 $\pm$ 3.87% sensitivity and 94.78 $\pm$ 0.87% specificity in a binary classification task that detected endometrioid adenocarcinoma (Malignant). Besides, in the external validation process, HIENet achieved an 84.50% accuracy in the four-class classification task, and it achieved an AUC of 0.9829 with a 77.97% (95% CI, 65.27%-87.71%) sensitivity and 100% (95% CI, 97.42%-100.00%) specificity. In summary, the proposed CADx approach, HIENet, outperformed three human experts and four end-to-end CNN-based classifiers on this small-scale dataset composed of 3,500 hematoxylin and eosin (H&E) images regarding overall classification performance.
The application to search ranking is one of the biggest machine learning success stories at Airbnb. Much of the initial gains were driven by a gradient boosted decision tree model. The gains, however, plateaued over time. This paper discusses the work done in applying neural networks in an attempt to break out of that plateau. We present our perspective not with the intention of pushing the frontier of new modeling techniques. Instead, ours is a story of the elements we found useful in applying neural networks to a real life product. Deep learning was steep learning for us. To other teams embarking on similar journeys, we hope an account of our struggles and triumphs will provide some useful pointers. Bon voyage!
Objective: Ultrahigh-resolution optical coherence microscopy (OCM) has recently demonstrated its potential for accurate diagnosis of human cervical diseases. One major challenge for clinical adoption, however, is the steep learning curve clinicians need to overcome to interpret OCM images. Developing an intelligent technique for computer-aided diagnosis (CADx) to accurately interpret OCM images will facilitate clinical adoption of the technology and improve patient care. Methods: 497 high-resolution 3-D OCM volumes (600 cross-sectional images each) were collected from 159 ex vivo specimens of 92 female patients. OCM image features were extracted using a convolutional neural network (CNN) model, concatenated with patient information (e.g., age, HPV results), and classified using a support vector machine classifier. Ten-fold cross-validations were utilized to test the performance of the CADx method in a five-class classification task and a binary classification task. Results: An 88.3 plus or minus 4.9% classification accuracy was achieved for five fine-grained classes of cervical tissue, namely normal, ectropion, low-grade and high-grade squamous intraepithelial lesions (LSIL and HSIL), and cancer. In the binary classification task (low-risk [normal, ectropion and LSIL] vs. high-risk [HSIL and cancer]), the CADx method achieved an area-under-the-curve (AUC) value of 0.959 with an 86.7 plus or minus 11.4% sensitivity and 93.5 plus or minus 3.8% specificity. Conclusion: The proposed deep-learning based CADx method outperformed three human experts. It was also able to identify morphological characteristics in OCM images that were consistent with histopathological interpretations. Significance: Label-free OCM imaging, combined with deep-learning based CADx methods, hold a great promise to be used in clinical settings for the effective screening and diagnosis of cervical diseases.
Convolutional neural networks are powerful tools for image segmentation and classification. Here, we use this method to identify and mark the heart region of Drosophila at different developmental stages in the cross-sectional images acquired by a custom optical coherence microscopy (OCM) system. With our well-trained convolutional neural network model, the heart regions through multiple heartbeat cycles can be marked with an intersection over union (IOU) of ~86%. Various morphological and dynamical cardiac parameters can be quantified accurately with automatically segmented heart regions. This study demonstrates an efficient heart segmentation method to analyze OCM images of the beating heart in Drosophila.
Although Generative Adversarial Networks (GANs) have shown remarkable success in various tasks, they still face challenges in generating high quality images. In this paper, we propose Stacked Generative Adversarial Networks (StackGAN) aiming at generating high-resolution photo-realistic images. First, we propose a two-stage generative adversarial network architecture, StackGAN-v1, for text-to-image synthesis. The Stage-I GAN sketches the primitive shape and colors of the object based on given text description, yielding low-resolution images. The Stage-II GAN takes Stage-I results and text descriptions as inputs, and generates high-resolution images with photo-realistic details. Second, an advanced multi-stage generative adversarial network architecture, StackGAN-v2, is proposed for both conditional and unconditional generative tasks. Our StackGAN-v2 consists of multiple generators and discriminators in a tree-like structure; images at multiple scales corresponding to the same scene are generated from different branches of the tree. StackGAN-v2 shows more stable training behavior than StackGAN-v1 by jointly approximating multiple distributions. Extensive experiments demonstrate that the proposed stacked generative adversarial networks significantly outperform other state-of-the-art methods in generating photo-realistic images.
Image feature point matching is a key step in Structure from Motion(SFM). However, it is becoming more and more time consuming because the number of images is getting larger and larger. In this paper, we proposed a GPU accelerated image matching method with improved Cascade Hashing. Firstly, we propose a Disk-Memory-GPU data exchange strategy and optimize the load order of data, so that the proposed method can deal with big data. Next, we parallelize the Cascade Hashing method on GPU. An improved parallel reduction and an improved parallel hashing ranking are proposed to fulfill this task. Finally, extensive experiments show that our image matching is about 20 times faster than SiftGPU on the same graphics card, nearly 100 times faster than the CPU CasHash method and hundreds of times faster than the CPU Kd-Tree based matching method. Further more, we introduce the epipolar constraint to the proposed method, and use the epipolar geometry to guide the feature matching procedure, which further reduces the matching cost.
Multiobjective optimization evolutionary algorithms have been successfully applied to solving constrained optimization problems. This paper proposes a new multiobjective optimization differential evolution algorithm for constrained optimization. Through a study of fitness landscapes using principle component analysis, we discover a statistic method of identifying the valley direction in a valley landscape. Based on this discovery, a new search operator called PCA-projection is constructed which projects an individual to a position along the valley direction. Then multiobjective optimization differential evolution using this projection operator is designed for constrained optimization. A comparative experiment has been implemented between the proposed algorithm and a state-of-the-art multiobjective differential evolution algorithm on a standard set of 24 benchmarks. Experimental results show that the new algorithm makes a significant improvement in terms of solution accuracy. The proposed algorithm is also competitive with ten evolutionary algorithms participated in an IEEE CEC 2006 competition and is ranked third in terms of the final rank.
The word "valley" is a popular term used in intuitively describing fitness landscapes. What is a valley on a fitness landscape? How to identify the direction and location of a valley if it exists? However, such questions are seldom rigorously studied in evolutionary optimization especially when the search space is a high dimensional continuous space. This paper presents two methods of studying valleys on a fitness landscape. The first method is based on the topological homeomorphism. It establishes a rigorous definition of a valley. A valley is regarded as a one-dimensional manifold. The second method takes a different viewpoint from statistics. It provides an algorithm of identifying the valley direction and location using principle component analysis.