Age-Net: An MRI-Based Iterative Framework for Biological Age Estimation

The concept of biological age (BA) - although important in clinical practice - is hard to grasp mainly due to lack of a clearly defined reference standard. For specific applications, especially in pediatrics, medical image data are used for BA estimation in a routine clinical context. Beyond this young age group, BA estimation is restricted to whole-body assessment using non-imaging indicators such as blood biomarkers, genetic and cellular data. However, various organ systems may exhibit different aging characteristics due to lifestyle and genetic factors. Thus, a whole-body assessment of the BA does not reflect the deviations of aging behavior between organs. To this end, we propose a new imaging-based framework for organ-specific BA estimation. As a first step, we introduce a chronological age (CA) estimation framework using deep convolutional neural networks (Age-Net). We quantitatively assess the performance of this framework in comparison to existing CA estimation approaches. Furthermore, we expand upon Age-Net with a novel iterative data-cleaning algorithm to segregate atypical-aging patients (BA $\not \approx$ CA) from the given population. In this manner, we hypothesize that the remaining population should approximate the true BA behaviour. For this initial study, we apply the proposed methodology on a brain magnetic resonance image (MRI) dataset containing healthy individuals as well as Alzheimer's patients with different dementia ratings. We demonstrate the correlation between the predicted BAs and the expected cognitive deterioration in Alzheimer's patients. A statistical and visualization-based analysis has provided evidence regarding the potential and current challenges of the proposed methodology.

Actor-Action Video Classification CSC 249/449 Spring 2020 Challenge Report

This technical report summarizes submissions and compiles from Actor-Action video classification challenge held as a final project in CSC 249/449 Machine Vision course (Spring 2020) at University of Rochester

V2VNet: Vehicle-to-Vehicle Communication for Joint Perception and Prediction

In this paper, we explore the use of vehicle-to-vehicle (V2V) communication to improve the perception and motion forecasting performance of self-driving vehicles. By intelligently aggregating the information received from multiple nearby vehicles, we can observe the same scene from different viewpoints. This allows us to see through occlusions and detect actors at long range, where the observations are very sparse or non-existent. We also show that our approach of sending compressed deep feature map activations achieves high accuracy while satisfying communication bandwidth requirements.

DSDNet: Deep Structured self-Driving Network

In this paper, we propose the Deep Structured self-Driving Network (DSDNet), which performs object detection, motion prediction, and motion planning with a single neural network. Towards this goal, we develop a deep structured energy based model which considers the interactions between actors and produces socially consistent multimodal future predictions. Furthermore, DSDNet explicitly exploits the predicted future distributions of actors to plan a safe maneuver by using a structured planning cost. Our sample-based formulation allows us to overcome the difficulty in probabilistic inference of continuous random variables. Experiments on a number of large-scale self driving datasets demonstrate that our model significantly outperforms the state-of-the-art.

Testing the Safety of Self-driving Vehicles by Simulating Perception and Prediction

We present a novel method for testing the safety of self-driving vehicles in simulation. We propose an alternative to sensor simulation, as sensor simulation is expensive and has large domain gaps. Instead, we directly simulate the outputs of the self-driving vehicle's perception and prediction system, enabling realistic motion planning testing. Specifically, we use paired data in the form of ground truth labels and real perception and prediction outputs to train a model that predicts what the online system will produce. Importantly, the inputs to our system consists of high definition maps, bounding boxes, and trajectories, which can be easily sketched by a test engineer in a matter of minutes. This makes our approach a much more scalable solution. Quantitative results on two large-scale datasets demonstrate that we can realistically test motion planning using our simulations.

End-to-end Contextual Perception and Prediction with Interaction Transformer

In this paper, we tackle the problem of detecting objects in 3D and forecasting their future motion in the context of self-driving. Towards this goal, we design a novel approach that explicitly takes into account the interactions between actors. To capture their spatial-temporal dependencies, we propose a recurrent neural network with a novel Transformer architecture, which we call the Interaction Transformer. Importantly, our model can be trained end-to-end, and runs in real-time. We validate our approach on two challenging real-world datasets: ATG4D and nuScenes. We show that our approach can outperform the state-of-the-art on both datasets. In particular, we significantly improve the social compliance between the estimated future trajectories, resulting in far fewer collisions between the predicted actors.

Fully Automated and Standardized Segmentation of Adipose Tissue Compartments by Deep Learning in Three-dimensional Whole-body MRI of Epidemiological Cohort Studies

Purpose: To enable fast and reliable assessment of subcutaneous and visceral adipose tissue compartments derived from whole-body MRI. Methods: Quantification and localization of different adipose tissue compartments from whole-body MR images is of high interest to examine metabolic conditions. For correct identification and phenotyping of individuals at increased risk for metabolic diseases, a reliable automatic segmentation of adipose tissue into subcutaneous and visceral adipose tissue is required. In this work we propose a 3D convolutional neural network (DCNet) to provide a robust and objective segmentation. In this retrospective study, we collected 1000 cases (66$\pm$ 13 years; 523 women) from the Tuebingen Family Study and from the German Center for Diabetes research (TUEF/DZD), as well as 300 cases (53$\pm$ 11 years; 152 women) from the German National Cohort (NAKO) database for model training, validation, and testing with a transfer learning between the cohorts. These datasets had variable imaging sequences, imaging contrasts, receiver coil arrangements, scanners and imaging field strengths. The proposed DCNet was compared against a comparable 3D UNet segmentation in terms of sensitivity, specificity, precision, accuracy, and Dice overlap. Results: Fast (5-7seconds) and reliable adipose tissue segmentation can be obtained with high Dice overlap (0.94), sensitivity (96.6%), specificity (95.1%), precision (92.1%) and accuracy (98.4%) from 3D whole-body MR datasets (field of view coverage 450x450x2000mm${}^3$). Segmentation masks and adipose tissue profiles are automatically reported back to the referring physician. Conclusion: Automatic adipose tissue segmentation is feasible in 3D whole-body MR data sets and is generalizable to different epidemiological cohort studies with the proposed DCNet.

Force myography benchmark data for hand gesture recognition and transfer learning

Force myography has recently gained increasing attention for hand gesture recognition tasks. However, there is a lack of publicly available benchmark data, with most existing studies collecting their own data often with custom hardware and for varying sets of gestures. This limits the ability to compare various algorithms, as well as the possibility for research to be done without first needing to collect data oneself. We contribute to the advancement of this field by making accessible a benchmark dataset collected using a commercially available sensor setup from 20 persons covering 18 unique gestures, in the hope of allowing further comparison of results as well as easier entry into this field of research. We illustrate one use-case for such data, showing how we can improve gesture recognition accuracy by utilising transfer learning to incorporate data from multiple other persons. This also illustrates that the dataset can serve as a benchmark dataset to facilitate research on transfer learning algorithms.

RadarNet: Exploiting Radar for Robust Perception of Dynamic Objects

We tackle the problem of exploiting Radar for perception in the context of self-driving as Radar provides complementary information to other sensors such as LiDAR or cameras in the form of Doppler velocity. The main challenges of using Radar are the noise and measurement ambiguities which have been a struggle for existing simple input or output fusion methods. To better address this, we propose a new solution that exploits both LiDAR and Radar sensors for perception. Our approach, dubbed RadarNet, features a voxel-based early fusion and an attention-based late fusion, which learn from data to exploit both geometric and dynamic information of Radar data. RadarNet achieves state-of-the-art results on two large-scale real-world datasets in the tasks of object detection and velocity estimation. We further show that exploiting Radar improves the perception capabilities of detecting faraway objects and understanding the motion of dynamic objects.