Learning From a Steady Hand: A Weakly Supervised Agent for Robot Assistance under Microscopy

This paper rethinks steady-hand robotic manipulation by using a weakly supervised framework that fuses calibration-aware perception with admittance control. Unlike conventional automation that relies on labor-intensive 2D labeling, our framework leverages reusable warm-up trajectories to extract implicit spatial information, thereby achieving calibration-aware, depth-resolved perception without the need for external fiducials or manual depth annotation. By explicitly characterizing residuals from observation and calibration models, the system establishes a task-space error budget from recorded warm-ups. The uncertainty budget yields a lateral closed-loop accuracy of approx. 49 micrometers at 95% confidence (worst-case testing subset) and a depth accuracy of <= 291 micrometers at 95% confidence bound during large in-plane moves. In a within-subject user study (N=8), the learned agent reduces overall NASA-TLX workload by 77.1% relative to the simple steady-hand assistance baseline. These results demonstrate that the weakly supervised agent improves the reliability of microscope-guided biomedical micromanipulation without introducing complex setup requirements, offering a practical framework for microscope-guided intervention.

LLaMEA-SAGE: Guiding Automated Algorithm Design with Structural Feedback from Explainable AI

Large language models have enabled automated algorithm design (AAD) by generating optimization algorithms directly from natural-language prompts. While evolutionary frameworks such as LLaMEA demonstrate strong exploratory capabilities across the algorithm design space, their search dynamics are entirely driven by fitness feedback, leaving substantial information about the generated code unused. We propose a mechanism for guiding AAD using feedback constructed from graph-theoretic and complexity features extracted from the abstract syntax trees of the generated algorithms, based on a surrogate model learned over an archive of evaluated solutions. Using explainable AI techniques, we identify features that substantially affect performance and translate them into natural-language mutation instructions that steer subsequent LLM-based code generation without restricting expressivity. We propose LLaMEA-SAGE, which integrates this feature-driven guidance into LLaMEA, and evaluate it across several benchmarks. We show that the proposed structured guidance achieves the same performance faster than vanilla LLaMEA in a small controlled experiment. In a larger-scale experiment using the MA-BBOB suite from the GECCO-MA-BBOB competition, our guided approach achieves superior performance compared to state-of-the-art AAD methods. These results demonstrate that signals derived from code can effectively bias LLM-driven algorithm evolution, bridging the gap between code structure and human-understandable performance feedback in automated algorithm design.

User Localization via Active Sensing with Electromagnetically Reconfigurable Antennas

This paper presents an end-to-end deep learning framework for electromagnetically reconfigurable antenna (ERA)-aided user localization with active sensing, where ERAs provide additional electromagnetic reconfigurability to diversify the received measurements and enhance localization informativeness. To balance sensing flexibility and overhead, we adopt a two-timescale design: the digital combiner is updated at each stage, while the ERA patterns are reconfigured at each substage via a spherical-harmonic representation. The proposed mechanism integrates attention-based feature extraction and LSTM-based temporal learning, enabling the system to learn an optimized sensing strategy and progressively refine the UE position estimate from sequential observations. Simulation results show that the proposed approach consistently outperforms conventional digital beamforming-only and single-stage sensing baselines in terms of localization accuracy. These results highlight the effectiveness of ERA-enabled active sensing for user localization in future wireless systems.

Tactile-Force Alignment in Vision-Language-Action Models for Force-aware Manipulation

Vision-Language-Action (VLA) models have recently emerged as powerful generalists for robotic manipulation. However, due to their predominant reliance on visual modalities, they fundamentally lack the physical intuition required for contact-rich tasks that require precise force regulation and physical reasoning. Existing attempts to incorporate vision-based tactile sensing into VLA models typically treat tactile inputs as auxiliary visual textures, thereby overlooking the underlying correlation between surface deformation and interaction dynamics. To bridge this gap, we propose a paradigm shift from tactile-vision alignment to tactile-force alignment. Here, we introduce TaF-VLA, a framework that explicitly grounds high-dimensional tactile observations in physical interaction forces. To facilitate this, we develop an automated tactile-force data acquisition device and curate the TaF-Dataset, comprising over 10 million synchronized tactile observations, 6-axis force/torque, and matrix force map. To align sequential tactile observations with interaction forces, the central component of our approach is the Tactile-Force Adapter (TaF-Adapter), a tactile sensor encoder that extracts discretized latent information for encoding tactile observations. This mechanism ensures that the learned representations capture history-dependent, noise-insensitive physical dynamics rather than static visual textures. Finally, we integrate this force-aligned encoder into a VLA backbone. Extensive real-world experiments demonstrate that TaF-VLA policy significantly outperforms state-of-the-art tactile-vision-aligned and vision-only baselines on contact-rich tasks, verifying its ability to achieve robust, force-aware manipulation through cross-modal physical reasoning.

Multimodal Visual Surrogate Compression for Alzheimer's Disease Classification

High-dimensional structural MRI (sMRI) images are widely used for Alzheimer's Disease (AD) diagnosis. Most existing methods for sMRI representation learning rely on 3D architectures (e.g., 3D CNNs), slice-wise feature extraction with late aggregation, or apply training-free feature extractions using 2D foundation models (e.g., DINO). However, these three paradigms suffer from high computational cost, loss of cross-slice relations, and limited ability to extract discriminative features, respectively. To address these challenges, we propose Multimodal Visual Surrogate Compression (MVSC). It learns to compress and adapt large 3D sMRI volumes into compact 2D features, termed as visual surrogates, which are better aligned with frozen 2D foundation models to extract powerful representations for final AD classification. MVSC has two key components: a Volume Context Encoder that captures global cross-slice context under textual guidance, and an Adaptive Slice Fusion module that aggregates slice-level information in a text-enhanced, patch-wise manner. Extensive experiments on three large-scale Alzheimer's disease benchmarks demonstrate our MVSC performs favourably on both binary and multi-class classification tasks compared against state-of-the-art methods.

Structured Semantic Information Helps Retrieve Better Examples for In-Context Learning in Few-Shot Relation Extraction

This paper presents several strategies to automatically obtain additional examples for in-context learning of one-shot relation extraction. Specifically, we introduce a novel strategy for example selection, in which new examples are selected based on the similarity of their underlying syntactic-semantic structure to the provided one-shot example. We show that this method results in complementary word choices and sentence structures when compared to LLM-generated examples. When these strategies are combined, the resulting hybrid system achieves a more holistic picture of the relations of interest than either method alone. Our framework transfers well across datasets (FS-TACRED and FS-FewRel) and LLM families (Qwen and Gemma). Overall, our hybrid selection method consistently outperforms alternative strategies and achieves state-of-the-art performance on FS-TACRED and strong gains on a customized FewRel subset.

MMSF: Multitask and Multimodal Supervised Framework for WSI Classification and Survival Analysis

Multimodal evidence is critical in computational pathology: gigapixel whole slide images capture tumor morphology, while patient-level clinical descriptors preserve complementary context for prognosis. Integrating such heterogeneous signals remains challenging because feature spaces exhibit distinct statistics and scales. We introduce MMSF, a multitask and multimodal supervised framework built on a linear-complexity MIL backbone that explicitly decomposes and fuses cross-modal information. MMSF comprises a graph feature extraction module embedding tissue topology at the patch level, a clinical data embedding module standardizing patient attributes, a feature fusion module aligning modality-shared and modality-specific representations, and a Mamba-based MIL encoder with multitask prediction heads. Experiments on CAMELYON16 and TCGA-NSCLC demonstrate 2.1--6.6\% accuracy and 2.2--6.9\% AUC improvements over competitive baselines, while evaluations on five TCGA survival cohorts yield 7.1--9.8\% C-index improvements compared with unimodal methods and 5.6--7.1\% over multimodal alternatives.

NeuraLSP: An Efficient and Rigorous Neural Left Singular Subspace Preconditioner for Conjugate Gradient Methods

Numerical techniques for solving partial differential equations (PDEs) are integral for many fields across science and engineering. Such techniques usually involve solving large, sparse linear systems, where preconditioning methods are critical. In recent years, neural methods, particularly graph neural networks (GNNs), have demonstrated their potential through accelerated convergence. Nonetheless, to extract connective structures, existing techniques aggregate discretized system matrices into graphs, and suffer from rank inflation and a suboptimal convergence rate. In this paper, we articulate NeuraLSP, a novel neural preconditioner combined with a novel loss metric that leverages the left singular subspace of the system matrix's near-nullspace vectors. By compressing spectral information into a fixed low-rank operator, our method exhibits both theoretical guarantees and empirical robustness to rank inflation, affording up to a 53% speedup. Besides the theoretical guarantees for our newly-formulated loss function, our comprehensive experimental results across diverse families of PDEs also substantiate the aforementioned theoretical advances.

Deep Learning based Three-stage Solution for ISAC Beamforming Optimization

In this paper, a general ISAC system where the base station (BS) communicates with multiple users and performs target detection is considered. Then, a sum communication rate maximization problem is formulated, subjected to the constraints of transmit power and the minimum sensing rates of users. To solve this problem, we develop a framework that leverages deep learning algorithms to provide a three-stage solution for ISAC beamforming. The three-stage beamforming optimization solution includes three modules: 1) an unsupervised learning based feature extraction algorithm is proposed to extract fixed-size latent features while keeping its essential information from the variable channel state information (CSI); 2) a reinforcement learning (RL) based beampattern optimization algorithm is proposed to search the desired beampattern according to the extracted features; 3) a supervised learning based beamforming reconstruction algorithm is proposed to reconstruct the beamforming vector from beampattern given by the RL agent. Simulation results demonstrate that the proposed three-stage solution outperforms the baseline RL algorithm by optimizing the intuitional beampattern rather than beamforming.

Structure-constrained Language-informed Diffusion Model for Unpaired Low-dose Computed Tomography Angiography Reconstruction

The application of iodinated contrast media (ICM) improves the sensitivity and specificity of computed tomography (CT) for a wide range of clinical indications. However, overdose of ICM can cause problems such as kidney damage and life-threatening allergic reactions. Deep learning methods can generate CT images of normal-dose ICM from low-dose ICM, reducing the required dose while maintaining diagnostic power. However, existing methods are difficult to realize accurate enhancement with incompletely paired images, mainly because of the limited ability of the model to recognize specific structures. To overcome this limitation, we propose a Structure-constrained Language-informed Diffusion Model (SLDM), a unified medical generation model that integrates structural synergy and spatial intelligence. First, the structural prior information of the image is effectively extracted to constrain the model inference process, thus ensuring structural consistency in the enhancement process. Subsequently, semantic supervision strategy with spatial intelligence is introduced, which integrates the functions of visual perception and spatial reasoning, thus prompting the model to achieve accurate enhancement. Finally, the subtraction angiography enhancement module is applied, which serves to improve the contrast of the ICM agent region to suitable interval for observation. Qualitative analysis of visual comparison and quantitative results of several metrics demonstrate the effectiveness of our method in angiographic reconstruction for low-dose contrast medium CT angiography.