From Signals to Causes: A Causal Signal Processing Framework for Robust and Interpretable Clinical Risk Prediction

Learning-based signal processing systems increasingly support high-stakes medical decisions using heterogeneous biomedical signals, including medical images, physiological time series, and clinical records. Despite strong predictive performance, many models rely on statistical correlations that are unstable across acquisition settings, patient populations, and institutional practices, limiting robustness, interpretability, and clinical trust. We advocate a causal signal processing perspective in which biomedical signals are treated as effects of latent generative mechanisms rather than as isolated predictive inputs. Using clinical risk prediction as a motivating example, we show how disease-related factors generate observable biomarkers, while acquisition processes act as confounders influencing signal appearance. In clinical disease risk prediction from chest CT scans and patient risk factors, correlational models may fail under scanner changes, whereas causal abstractions remain invariant. Building on this view, we propose a unifying conceptual framework integrating causal modeling with learning-based signal processing and neuro-symbolic reasoning. Statistical models extract multimodal representations that are mapped to interpretable causal abstractions and combined with symbolic knowledge encoding clinical risk factors and guidelines. This structure enables clinically grounded explanations, counterfactual reasoning about hypothetical interventions, and improved robustness to distribution shifts arising from changes in acquisition conditions or screening policies. Rather than introducing a specific algorithm, this article presents schematic causal structures and a comparative analysis of correlation-based, causal, and neuro-symbolic approaches to guide the design of robust and interpretable medical decision-support systems.

AWGformer: Adaptive Wavelet-Guided Transformer for Multi-Resolution Time Series Forecasting

Time series forecasting requires capturing patterns across multiple temporal scales while maintaining computational efficiency. This paper introduces AWGformer, a novel architecture that integrates adaptive wavelet decomposition with cross-scale attention mechanisms for enhanced multi-variate time series prediction. Our approach comprises: (1) an Adaptive Wavelet Decomposition Module (AWDM) that dynamically selects optimal wavelet bases and decomposition levels based on signal characteristics; (2) a Cross-Scale Feature Fusion (CSFF) mechanism that captures interactions between different frequency bands through learnable coupling matrices; (3) a Frequency-Aware Multi-Head Attention (FAMA) module that weights attention heads according to their frequency selectivity; (4) a Hierarchical Prediction Network (HPN) that generates forecasts at multiple resolutions before reconstruction. Extensive experiments on benchmark datasets demonstrate that AWGformer achieves significant average improvements over state-of-the-art methods, with particular effectiveness on multi-scale and non-stationary time series. Theoretical analysis provides convergence guarantees and establishes the connection between our wavelet-guided attention and classical signal processing principles.

AgriWorld:A World Tools Protocol Framework for Verifiable Agricultural Reasoning with Code-Executing LLM Agents

Foundation models for agriculture are increasingly trained on massive spatiotemporal data (e.g., multi-spectral remote sensing, soil grids, and field-level management logs) and achieve strong performance on forecasting and monitoring. However, these models lack language-based reasoning and interactive capabilities, limiting their usefulness in real-world agronomic workflows. Meanwhile, large language models (LLMs) excel at interpreting and generating text, but cannot directly reason over high-dimensional, heterogeneous agricultural datasets. We bridge this gap with an agentic framework for agricultural science. It provides a Python execution environment, AgriWorld, exposing unified tools for geospatial queries over field parcels, remote-sensing time-series analytics, crop growth simulation, and task-specific predictors (e.g., yield, stress, and disease risk). On top of this environment, we design a multi-turn LLM agent, Agro-Reflective, that iteratively writes code, observes execution results, and refines its analysis via an execute-observe-refine loop. We introduce AgroBench, with scalable data generation for diverse agricultural QA spanning lookups, forecasting, anomaly detection, and counterfactual "what-if" analysis. Experiments outperform text-only and direct tool-use baselines, validating execution-driven reflection for reliable agricultural reasoning.

Position: Why a Dynamical Systems Perspective is Needed to Advance Time Series Modeling

Time series (TS) modeling has come a long way from early statistical, mainly linear, approaches to the current trend in TS foundation models. With a lot of hype and industrial demand in this field, it is not always clear how much progress there really is. To advance TS forecasting and analysis to the next level, here we argue that the field needs a dynamical systems (DS) perspective. TS of observations from natural or engineered systems almost always originate from some underlying DS, and arguably access to its governing equations would yield theoretically optimal forecasts. This is the promise of DS reconstruction (DSR), a class of ML/AI approaches that aim to infer surrogate models of the underlying DS from data. But models based on DS principles offer other profound advantages: Beyond short-term forecasts, they enable to predict the long-term statistics of an observed system, which in many practical scenarios may be the more relevant quantities. DS theory furthermore provides domain-independent theoretical insight into mechanisms underlying TS generation, and thereby will inform us, e.g., about upper bounds on performance of any TS model, generalization into unseen regimes as in tipping points, or potential control strategies. After reviewing some of the central concepts, methods, measures, and models in DS theory and DSR, we will discuss how insights from this field can advance TS modeling in crucial ways, enabling better forecasting with much lower computational and memory footprints. We conclude with a number of specific suggestions for translating insights from DSR into TS modeling.

TS-Debate: Multimodal Collaborative Debate for Zero-Shot Time Series Reasoning

Recent progress at the intersection of large language models (LLMs) and time series (TS) analysis has revealed both promise and fragility. While LLMs can reason over temporal structure given carefully engineered context, they often struggle with numeric fidelity, modality interference, and principled cross-modal integration. We present TS-Debate, a modality-specialized, collaborative multi-agent debate framework for zero-shot time series reasoning. TS-Debate assigns dedicated expert agents to textual context, visual patterns, and numerical signals, preceded by explicit domain knowledge elicitation, and coordinates their interaction via a structured debate protocol. Reviewer agents evaluate agent claims using a verification-conflict-calibration mechanism, supported by lightweight code execution and numerical lookup for programmatic verification. This architecture preserves modality fidelity, exposes conflicting evidence, and mitigates numeric hallucinations without task-specific fine-tuning. Across 20 tasks spanning three public benchmarks, TS-Debate achieves consistent and significant performance improvements over strong baselines, including standard multimodal debate in which all agents observe all inputs.

Real time fault detection in 3D printers using Convolutional Neural Networks and acoustic signals

The reliability and quality of 3D printing processes are critically dependent on the timely detection of mechanical faults. Traditional monitoring methods often rely on visual inspection and hardware sensors, which can be both costly and limited in scope. This paper explores a scalable and contactless method for the use of real-time audio signal analysis for detecting mechanical faults in 3D printers. By capturing and classifying acoustic emissions during the printing process, we aim to identify common faults such as nozzle clogging, filament breakage, pully skipping and various other mechanical faults. Utilizing Convolutional neural networks, we implement algorithms capable of real-time audio classification to detect these faults promptly. Our methodology involves conducting a series of controlled experiments to gather audio data, followed by the application of advanced machine learning models for fault detection. Additionally, we review existing literature on audio-based fault detection in manufacturing and 3D printing to contextualize our research within the broader field. Preliminary results demonstrate that audio signals, when analyzed with machine learning techniques, provide a reliable and cost-effective means of enhancing real-time fault detection.

CLEF HIPE-2026: Evaluating Accurate and Efficient Person-Place Relation Extraction from Multilingual Historical Texts

HIPE-2026 is a CLEF evaluation lab dedicated to person-place relation extraction from noisy, multilingual historical texts. Building on the HIPE-2020 and HIPE-2022 campaigns, it extends the series toward semantic relation extraction by targeting the task of identifying person--place associations in multiple languages and time periods. Systems are asked to classify relations of two types - $at$ ("Has the person ever been at this place?") and $isAt$ ("Is the person located at this place around publication time?") - requiring reasoning over temporal and geographical cues. The lab introduces a three-fold evaluation profile that jointly assesses accuracy, computational efficiency, and domain generalization. By linking relation extraction to large-scale historical data processing, HIPE-2026 aims to support downstream applications in knowledge-graph construction, historical biography reconstruction, and spatial analysis in digital humanities.

Linked Data Classification using Neurochaos Learning

Neurochaos Learning (NL) has shown promise in recent times over traditional deep learning due to its two key features: ability to learn from small sized training samples, and low compute requirements. In prior work, NL has been implemented and extensively tested on separable and time series data, and demonstrated its superior performance on both classification and regression tasks. In this paper, we investigate the next step in NL, viz., applying NL to linked data, in particular, data that is represented in the form of knowledge graphs. We integrate linked data into NL by implementing node aggregation on knowledge graphs, and then feeding the aggregated node features to the simplest NL architecture: ChaosNet. We demonstrate the results of our implementation on homophilic graph datasets as well as heterophilic graph datasets of verying heterophily. We show better efficacy of our approach on homophilic graphs than on heterophilic graphs. While doing so, we also present our analysis of the results, as well as suggestions for future work.

AIRS-Bench: a Suite of Tasks for Frontier AI Research Science Agents

LLM agents hold significant promise for advancing scientific research. To accelerate this progress, we introduce AIRS-Bench (the AI Research Science Benchmark), a suite of 20 tasks sourced from state-of-the-art machine learning papers. These tasks span diverse domains, including language modeling, mathematics, bioinformatics, and time series forecasting. AIRS-Bench tasks assess agentic capabilities over the full research lifecycle -- including idea generation, experiment analysis and iterative refinement -- without providing baseline code. The AIRS-Bench task format is versatile, enabling easy integration of new tasks and rigorous comparison across different agentic frameworks. We establish baselines using frontier models paired with both sequential and parallel scaffolds. Our results show that agents exceed human SOTA in four tasks but fail to match it in sixteen others. Even when agents surpass human benchmarks, they do not reach the theoretical performance ceiling for the underlying tasks. These findings indicate that AIRS-Bench is far from saturated and offers substantial room for improvement. We open-source the AIRS-Bench task definitions and evaluation code to catalyze further development in autonomous scientific research.

Policy4OOD: A Knowledge-Guided World Model for Policy Intervention Simulation against the Opioid Overdose Crisis

The opioid epidemic remains one of the most severe public health crises in the United States, yet evaluating policy interventions before implementation is difficult: multiple policies interact within a dynamic system where targeting one risk pathway may inadvertently amplify another. We argue that effective opioid policy evaluation requires three capabilities -- forecasting future outcomes under current policies, counterfactual reasoning about alternative past decisions, and optimization over candidate interventions -- and propose to unify them through world modeling. We introduce Policy4OOD, a knowledge-guided spatio-temporal world model that addresses three core challenges: what policies prescribe, where effects manifest, and when effects unfold.Policy4OOD jointly encodes policy knowledge graphs, state-level spatial dependencies, and socioeconomic time series into a policy-conditioned Transformer that forecasts future opioid outcomes.Once trained, the world model serves as a simulator: forecasting requires only a forward pass, counterfactual analysis substitutes alternative policy encodings in the historical sequence, and policy optimization employs Monte Carlo Tree Search over the learned simulator. To support this framework, we construct a state-level monthly dataset (2019--2024) integrating opioid mortality, socioeconomic indicators, and structured policy encodings. Experiments demonstrate that spatial dependencies and structured policy knowledge significantly improve forecasting accuracy, validating each architectural component and the potential of world modeling for data-driven public health decision support.