Domain knowledge refers to the in-depth understanding, expertise, and familiarity with a specific subject, industry, field, or area of special interest. The existing benchmarks are all lack of an overall design for domain knowledge evaluation. Holding the belief that the real ability of domain language understanding can only be fairly evaluated by an comprehensive and in-depth benchmark, we introduces the Domma, a Domain Mastery Benchmark. DomMa targets at testing Large Language Models (LLMs) on their domain knowledge understanding, it features extensive domain coverage, large data volume, and a continually updated data set based on Chinese 112 first-level subject classifications. DomMa consist of 100,000 questions in both Chinese and English sourced from graduate entrance examinations and undergraduate exams in Chinese college. We have also propose designs to make benchmark and evaluation process more suitable to LLMs.
Recent large language models (LLMs) in the general domain, such as ChatGPT, have shown remarkable success in following instructions and producing human-like responses. However, such language models have not been tailored to the medical domain, resulting in poor answer accuracy and inability to give plausible recommendations for medical diagnosis, medications, etc. To address this issue, we collected more than 700 diseases and their corresponding symptoms, required medical tests, and recommended medications, from which we generated 5K doctor-patient conversations. In addition, we obtained 200K real patient-doctor conversations from online Q\&A medical consultation sites. By fine-tuning LLMs using these 205k doctor-patient conversations, the resulting models emerge with great potential to understand patients' needs, provide informed advice, and offer valuable assistance in a variety of medical-related fields. The integration of these advanced language models into healthcare can revolutionize the way healthcare professionals and patients communicate, ultimately improving the overall efficiency and quality of patient care and outcomes. In addition, we made public all the source codes, datasets, and model weights to facilitate the further development of dialogue models in the medical field. The training data, codes, and weights of this project are available at: The training data, codes, and weights of this project are available at: https://github.com/Kent0n-Li/ChatDoctor.
The following three factors restrict the application of existing low-light image enhancement methods: unpredictable brightness degradation and noise, inherent gap between metric-favorable and visual-friendly versions, and the limited paired training data. To address these limitations, we propose an implicit Neural Representation method for Cooperative low-light image enhancement, dubbed NeRCo. It robustly recovers perceptual-friendly results in an unsupervised manner. Concretely, NeRCo unifies the diverse degradation factors of real-world scenes with a controllable fitting function, leading to better robustness. In addition, for the output results, we introduce semantic-orientated supervision with priors from the pre-trained vision-language model. Instead of merely following reference images, it encourages results to meet subjective expectations, finding more visual-friendly solutions. Further, to ease the reliance on paired data and reduce solution space, we develop a dual-closed-loop constrained enhancement module. It is trained cooperatively with other affiliated modules in a self-supervised manner. Finally, extensive experiments demonstrate the robustness and superior effectiveness of our proposed NeRCo. Our code is available at https://github.com/Ysz2022/NeRCo.
Segmentation of COVID-19 lesions can assist physicians in better diagnosis and treatment of COVID-19. However, there are few relevant studies due to the lack of detailed information and high-quality annotation in the COVID-19 dataset. To solve the above problem, we propose C2FVL, a Coarse-to-Fine segmentation framework via Vision-Language alignment to merge text information containing the number of lesions and specific locations of image information. The introduction of text information allows the network to achieve better prediction results on challenging datasets. We conduct extensive experiments on two COVID-19 datasets including chest X-ray and CT, and the results demonstrate that our proposed method outperforms other state-of-the-art segmentation methods.
We consider optimizing a function network in the noise-free grey-box setting with RKHS function classes, where the exact intermediate results are observable. We assume that the structure of the network is known (but not the underlying functions comprising it), and we study three types of structures: (1) chain: a cascade of scalar-valued functions, (2) multi-output chain: a cascade of vector-valued functions, and (3) feed-forward network: a fully connected feed-forward network of scalar-valued functions. We propose a sequential upper confidence bound based algorithm GPN-UCB along with a general theoretical upper bound on the cumulative regret. For the Mat\'ern kernel, we additionally propose a non-adaptive sampling based method along with its theoretical upper bound on the simple regret. We also provide algorithm-independent lower bounds on the simple regret and cumulative regret, showing that GPN-UCB is near-optimal for chains and multi-output chains in broad cases of interest.
Neural network (NN) based approaches for super-resolution MRI typically require high-SNR high-resolution reference data acquired in many subjects, which is time consuming and a barrier to feasible and accessible implementation. We propose to train NNs for Super-Resolution using Noisy Reference data (SRNR), leveraging the mechanism of the classic NN-based denoising method Noise2Noise. We systematically demonstrate that results from NNs trained using noisy and high-SNR references are similar for both simulated and empirical data. SRNR suggests a smaller number of repetitions of high-resolution reference data can be used to simplify the training data preparation for super-resolution MRI.
Medical image segmentation is one of the most fundamental tasks concerning medical information analysis. Various solutions have been proposed so far, including many deep learning-based techniques, such as U-Net, FC-DenseNet, etc. However, high-precision medical image segmentation remains a highly challenging task due to the existence of inherent magnification and distortion in medical images as well as the presence of lesions with similar density to normal tissues. In this paper, we propose TFCNs (Transformers for Fully Convolutional denseNets) to tackle the problem by introducing ResLinear-Transformer (RL-Transformer) and Convolutional Linear Attention Block (CLAB) to FC-DenseNet. TFCNs is not only able to utilize more latent information from the CT images for feature extraction, but also can capture and disseminate semantic features and filter non-semantic features more effectively through the CLAB module. Our experimental results show that TFCNs can achieve state-of-the-art performance with dice scores of 83.72\% on the Synapse dataset. In addition, we evaluate the robustness of TFCNs for lesion area effects on the COVID-19 public datasets. The Python code will be made publicly available on https://github.com/HUANGLIZI/TFCNs.
Deep learning has been widely used in medical image segmentation and other aspects. However, the performance of existing medical image segmentation models has been limited by the challenge of obtaining sufficient number of high-quality data with the high cost of data annotation. To overcome the limitation, we propose a new vision-language medical image segmentation model LViT (Language meets Vision Transformer). In our model, medical text annotation is introduced to compensate for the quality deficiency in image data. In addition, the text information can guide the generation of pseudo labels to a certain extent and further guarantee the quality of pseudo labels in semi-supervised learning. We also propose the Exponential Pseudo label Iteration mechanism (EPI) to help extend the semi-supervised version of LViT and the Pixel-Level Attention Module (PLAM) to preserve local features of images. In our model, LV (Language-Vision) loss is designed to supervise the training of unlabeled images using text information directly. To validate the performance of LViT, we construct multimodal medical segmentation datasets (image + text) containing pathological images, X-rays,etc. Experimental results show that our proposed LViT has better segmentation performance in both fully and semi-supervised conditions. Code and datasets are available at https://github.com/HUANGLIZI/LViT.
Supervised learning has been widely used for attack detection, which requires large amounts of high-quality data and labels. However, the data is often imbalanced and sufficient annotations are difficult to obtain. Moreover, these supervised models are subject to real-world deployment issues, such as defending against unseen artificial attacks. We propose a semi-supervised fine-grained attack categorization framework consisting of an encoder and a two-branch structure to integrate information from labeled and unlabeled data to tackle these practical challenges. This framework can be generalized to different supervised models. The multilayer perceptron with residual connection and batch normalization is used as the encoder to extract features and reduce the complexity. The Recurrent Prototype Module (RPM) is proposed to train the encoder effectively in a semi-supervised manner. To alleviate the problem of data imbalance, we introduce the Weight-Task Consistency (WTC) into the iterative process of RPM by assigning larger weights to classes with fewer samples in the loss function. In addition, to cope with new attacks in real-world deployment, we further propose an Active Adaption Resampling (AAR) method, which can better discover the distribution of the unseen sample data and adapt the parameters of the encoder. Experimental results show that our model outperforms the state-of-the-art semi-supervised attack detection methods with a general 5% improvement in classification accuracy and a 90% reduction in training time.