Thyroid cancer is the most common endocrine malignancy, and accurately distinguishing between benign and malignant thyroid tumors is crucial for developing effective treatment plans in clinical practice. Pathologically, thyroid tumors pose diagnostic challenges due to improper specimen sampling. In this study, we have designed a three-stage model using representation learning to integrate pixel-level and slice-level annotations for distinguishing thyroid tumors. This structure includes a pathology structure recognition method to predict structures related to thyroid tumors, an encoder-decoder network to extract pixel-level annotation information by learning the feature representations of image blocks, and an attention-based learning mechanism for the final classification task. This mechanism learns the importance of different image blocks in a pathological region, globally considering the information from each block. In the third stage, all information from the image blocks in a region is aggregated using attention mechanisms, followed by classification to determine the category of the region. Experimental results demonstrate that our proposed method can predict microscopic structures more accurately. After color-coding, the method achieves results on unstained pathology slides that approximate the quality of Hematoxylin and eosin staining, reducing the need for stained pathology slides. Furthermore, by leveraging the concept of indirect measurement and extracting polarized features from structures correlated with lesions, the proposed method can also classify samples where membrane structures cannot be obtained through sampling, providing a potential objective and highly accurate indirect diagnostic technique for thyroid tumors.
Classifying hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) is a critical step in treatment selection and prognosis evaluation for patients with liver diseases. Traditional histopathological diagnosis poses challenges in this context. In this study, we introduce a novel polarization and radiomics feature fusion network, which combines polarization features obtained from Mueller matrix images of liver pathological samples with radiomics features derived from corresponding pathological images to classify HCC and ICC. Our fusion network integrates a two-tier fusion approach, comprising early feature-level fusion and late classification-level fusion. By harnessing the strengths of polarization imaging techniques and image feature-based machine learning, our proposed fusion network significantly enhances classification accuracy. Notably, even at reduced imaging resolutions, the fusion network maintains robust performance due to the additional information provided by polarization features, which may not align with human visual perception. Our experimental results underscore the potential of this fusion network as a powerful tool for computer-aided diagnosis of HCC and ICC, showcasing the benefits and prospects of integrating polarization imaging techniques into the current image-intensive digital pathological diagnosis. We aim to contribute this innovative approach to top-tier journals, offering fresh insights and valuable tools in the fields of medical imaging and cancer diagnosis. By introducing polarization imaging into liver cancer classification, we demonstrate its interdisciplinary potential in addressing challenges in medical image analysis, promising advancements in medical imaging and cancer diagnosis.
We introduce Gaussian-Flow, a novel point-based approach for fast dynamic scene reconstruction and real-time rendering from both multi-view and monocular videos. In contrast to the prevalent NeRF-based approaches hampered by slow training and rendering speeds, our approach harnesses recent advancements in point-based 3D Gaussian Splatting (3DGS). Specifically, a novel Dual-Domain Deformation Model (DDDM) is proposed to explicitly model attribute deformations of each Gaussian point, where the time-dependent residual of each attribute is captured by a polynomial fitting in the time domain, and a Fourier series fitting in the frequency domain. The proposed DDDM is capable of modeling complex scene deformations across long video footage, eliminating the need for training separate 3DGS for each frame or introducing an additional implicit neural field to model 3D dynamics. Moreover, the explicit deformation modeling for discretized Gaussian points ensures ultra-fast training and rendering of a 4D scene, which is comparable to the original 3DGS designed for static 3D reconstruction. Our proposed approach showcases a substantial efficiency improvement, achieving a $5\times$ faster training speed compared to the per-frame 3DGS modeling. In addition, quantitative results demonstrate that the proposed Gaussian-Flow significantly outperforms previous leading methods in novel view rendering quality. Project page: https://nju-3dv.github.io/projects/Gaussian-Flow
Image animation is a key task in computer vision which aims to generate dynamic visual content from static image. Recent image animation methods employ neural based rendering technique to generate realistic animations. Despite these advancements, achieving fine-grained and controllable image animation guided by text remains challenging, particularly for open-domain images captured in diverse real environments. In this paper, we introduce an open domain image animation method that leverages the motion prior of video diffusion model. Our approach introduces targeted motion area guidance and motion strength guidance, enabling precise control the movable area and its motion speed. This results in enhanced alignment between the animated visual elements and the prompting text, thereby facilitating a fine-grained and interactive animation generation process for intricate motion sequences. We validate the effectiveness of our method through rigorous experiments on an open-domain dataset, with the results showcasing its superior performance. Project page can be found at https://animationai.github.io/AnimateAnything.
We present a novel differentiable point-based rendering framework for material and lighting decomposition from multi-view images, enabling editing, ray-tracing, and real-time relighting of the 3D point cloud. Specifically, a 3D scene is represented as a set of relightable 3D Gaussian points, where each point is additionally associated with a normal direction, BRDF parameters, and incident lights from different directions. To achieve robust lighting estimation, we further divide incident lights of each point into global and local components, as well as view-dependent visibilities. The 3D scene is optimized through the 3D Gaussian Splatting technique while BRDF and lighting are decomposed by physically-based differentiable rendering. Moreover, we introduce an innovative point-based ray-tracing approach based on the bounding volume hierarchy for efficient visibility baking, enabling real-time rendering and relighting of 3D Gaussian points with accurate shadow effects. Extensive experiments demonstrate improved BRDF estimation and novel view rendering results compared to state-of-the-art material estimation approaches. Our framework showcases the potential to revolutionize the mesh-based graphics pipeline with a relightable, traceable, and editable rendering pipeline solely based on point cloud. Project page:https://nju-3dv.github.io/projects/Relightable3DGaussian/.
Recent advances in generative AI have unveiled significant potential for the creation of 3D content. However, current methods either apply a pre-trained 2D diffusion model with the time-consuming score distillation sampling (SDS), or a direct 3D diffusion model trained on limited 3D data losing generation diversity. In this work, we approach the problem by employing a multi-view 2.5D diffusion fine-tuned from a pre-trained 2D diffusion model. The multi-view 2.5D diffusion directly models the structural distribution of 3D data, while still maintaining the strong generalization ability of the original 2D diffusion model, filling the gap between 2D diffusion-based and direct 3D diffusion-based methods for 3D content generation. During inference, multi-view normal maps are generated using the 2.5D diffusion, and a novel differentiable rasterization scheme is introduced to fuse the almost consistent multi-view normal maps into a consistent 3D model. We further design a normal-conditioned multi-view image generation module for fast appearance generation given the 3D geometry. Our method is a one-pass diffusion process and does not require any SDS optimization as post-processing. We demonstrate through extensive experiments that, our direct 2.5D generation with the specially-designed fusion scheme can achieve diverse, mode-seeking-free, and high-fidelity 3D content generation in only 10 seconds. Project page: https://nju-3dv.github.io/projects/direct25.
Image animation is a key task in computer vision which aims to generate dynamic visual content from static image. Recent image animation methods employ neural based rendering technique to generate realistic animations. Despite these advancements, achieving fine-grained and controllable image animation guided by text remains challenging, particularly for open-domain images captured in diverse real environments. In this paper, we introduce an open domain image animation method that leverages the motion prior of video diffusion model. Our approach introduces targeted motion area guidance and motion strength guidance, enabling precise control the movable area and its motion speed. This results in enhanced alignment between the animated visual elements and the prompting text, thereby facilitating a fine-grained and interactive animation generation process for intricate motion sequences. We validate the effectiveness of our method through rigorous experiments on an open-domain dataset, with the results showcasing its superior performance. The source code and model will be made publicly available upon publication.
Large language models (LLMs) have dramatically enhanced the field of language intelligence, as demonstrably evidenced by their formidable empirical performance across a spectrum of complex reasoning tasks. Additionally, theoretical proofs have illuminated their emergent reasoning capabilities, providing a compelling showcase of their advanced cognitive abilities in linguistic contexts. Critical to their remarkable efficacy in handling complex reasoning tasks, LLMs leverage the intriguing chain-of-thought (CoT) reasoning techniques, obliging them to formulate intermediate steps en route to deriving an answer. The CoT reasoning approach has not only exhibited proficiency in amplifying reasoning performance but also in enhancing interpretability, controllability, and flexibility. In light of these merits, recent research endeavors have extended CoT reasoning methodologies to nurture the development of autonomous language agents, which adeptly adhere to language instructions and execute actions within varied environments. This survey paper orchestrates a thorough discourse, penetrating vital research dimensions, encompassing: (i) the foundational mechanics of CoT techniques, with a focus on elucidating the circumstances and justification behind its efficacy; (ii) the paradigm shift in CoT; and (iii) the burgeoning of language agents fortified by CoT approaches. Prospective research avenues envelop explorations into generalization, efficiency, customization, scaling, and safety. This paper caters to a wide audience, including beginners seeking comprehensive knowledge of CoT reasoning and language agents, as well as experienced researchers interested in foundational mechanics and engaging in cutting-edge discussions on these topics. A repository for the related papers is available at https://github.com/Zoeyyao27/CoT-Igniting-Agent.
In this paper, we present Consistent4D, a novel approach for generating 4D dynamic objects from uncalibrated monocular videos. Uniquely, we cast the 360-degree dynamic object reconstruction as a 4D generation problem, eliminating the need for tedious multi-view data collection and camera calibration. This is achieved by leveraging the object-level 3D-aware image diffusion model as the primary supervision signal for training Dynamic Neural Radiance Fields (DyNeRF). Specifically, we propose a Cascade DyNeRF to facilitate stable convergence and temporal continuity under the supervision signal which is discrete along the time axis. To achieve spatial and temporal consistency, we further introduce an Interpolation-driven Consistency Loss. It is optimized by minimizing the discrepancy between rendered frames from DyNeRF and interpolated frames from a pre-trained video interpolation model. Extensive experiments show that our Consistent4D can perform competitively to prior art alternatives, opening up new possibilities for 4D dynamic object generation from monocular videos, whilst also demonstrating advantage for conventional text-to-3D generation tasks. Our project page is https://consistent4d.github.io/.
Data sparsity and cold-start problems are persistent challenges in recommendation systems. Cross-domain recommendation (CDR) is a promising solution that utilizes knowledge from the source domain to improve the recommendation performance in the target domain. Previous CDR approaches have mainly followed the Embedding and Mapping (EMCDR) framework, which involves learning a mapping function to facilitate knowledge transfer. However, these approaches necessitate re-engineering and re-training the network structure to incorporate transferrable knowledge, which can be computationally expensive and may result in catastrophic forgetting of the original knowledge. In this paper, we present a scalable and efficient paradigm to address data sparsity and cold-start issues in CDR, named CDR-Adapter, by decoupling the original recommendation model from the mapping function, without requiring re-engineering the network structure. Specifically, CDR-Adapter is a novel plug-and-play module that employs adapter modules to align feature representations, allowing for flexible knowledge transfer across different domains and efficient fine-tuning with minimal training costs. We conducted extensive experiments on the benchmark dataset, which demonstrated the effectiveness of our approach over several state-of-the-art CDR approaches.
* 8 pages, 4 figures, 5 tables, Proceedings of the 46th International
ACM SIGIR Conference on Research and Development in Information Retrieval
Workshop on eCommerce