Bridging the Gap in Missing Modalities: Leveraging Knowledge Distillation and Style Matching for Brain Tumor Segmentation

Accurate and reliable brain tumor segmentation, particularly when dealing with missing modalities, remains a critical challenge in medical image analysis. Previous studies have not fully resolved the challenges of tumor boundary segmentation insensitivity and feature transfer in the absence of key imaging modalities. In this study, we introduce MST-KDNet, aimed at addressing these critical issues. Our model features Multi-Scale Transformer Knowledge Distillation to effectively capture attention weights at various resolutions, Dual-Mode Logit Distillation to improve the transfer of knowledge, and a Global Style Matching Module that integrates feature matching with adversarial learning. Comprehensive experiments conducted on the BraTS and FeTS 2024 datasets demonstrate that MST-KDNet surpasses current leading methods in both Dice and HD95 scores, particularly in conditions with substantial modality loss. Our approach shows exceptional robustness and generalization potential, making it a promising candidate for real-world clinical applications. Our source code is available at https://github.com/Quanato607/MST-KDNet.

Improving Generalization Ability of Robotic Imitation Learning by Resolving Causal Confusion in Observations

Recent developments in imitation learning have considerably advanced robotic manipulation. However, current techniques in imitation learning can suffer from poor generalization, limiting performance even under relatively minor domain shifts. In this work, we aim to enhance the generalization capabilities of complex imitation learning algorithms to handle unpredictable changes from the training environments to deployment environments. To avoid confusion caused by observations that are not relevant to the target task, we propose to explicitly learn the causal relationship between observation components and expert actions, employing a framework similar to [6], where a causal structural function is learned by intervention on the imitation learning policy. Disentangling the feature representation from image input as in [6] is hard to satisfy in complex imitation learning process in robotic manipulation, we theoretically clarify that this requirement is not necessary in causal relationship learning. Therefore, we propose a simple causal structure learning framework that can be easily embedded in recent imitation learning architectures, such as the Action Chunking Transformer [31]. We demonstrate our approach using a simulation of the ALOHA [31] bimanual robot arms in Mujoco, and show that the method can considerably mitigate the generalization problem of existing complex imitation learning algorithms.

Towards Practical Alzheimer's Disease Diagnosis: A Lightweight and Interpretable Spiking Neural Model

Early diagnosis of Alzheimer's Disease (AD), especially at the mild cognitive impairment (MCI) stage, is vital yet hindered by subjective assessments and the high cost of multimodal imaging modalities. Although deep learning methods offer automated alternatives, their energy inefficiency and computational demands limit real-world deployment, particularly in resource-constrained settings. As a brain-inspired paradigm, spiking neural networks (SNNs) are inherently well-suited for modeling the sparse, event-driven patterns of neural degeneration in AD, offering a promising foundation for interpretable and low-power medical diagnostics. However, existing SNNs often suffer from weak expressiveness and unstable training, which restrict their effectiveness in complex medical tasks. To address these limitations, we propose FasterSNN, a hybrid neural architecture that integrates biologically inspired LIF neurons with region-adaptive convolution and multi-scale spiking attention. This design enables sparse, efficient processing of 3D MRI while preserving diagnostic accuracy. Experiments on benchmark datasets demonstrate that FasterSNN achieves competitive performance with substantially improved efficiency and stability, supporting its potential for practical AD screening. Our source code is available at https://github.com/wuchangw/FasterSNN.

Tool-Star: Empowering LLM-Brained Multi-Tool Reasoner via Reinforcement Learning

Recently, large language models (LLMs) have shown remarkable reasoning capabilities via large-scale reinforcement learning (RL). However, leveraging the RL algorithm to empower effective multi-tool collaborative reasoning in LLMs remains an open challenge. In this paper, we introduce Tool-Star, an RL-based framework designed to empower LLMs to autonomously invoke multiple external tools during stepwise reasoning. Tool-Star integrates six types of tools and incorporates systematic designs in both data synthesis and training. To address the scarcity of tool-use data, we propose a general tool-integrated reasoning data synthesis pipeline, which combines tool-integrated prompting with hint-based sampling to automatically and scalably generate tool-use trajectories. A subsequent quality normalization and difficulty-aware classification process filters out low-quality samples and organizes the dataset from easy to hard. Furthermore, we propose a two-stage training framework to enhance multi-tool collaborative reasoning by: (1) cold-start fine-tuning, which guides LLMs to explore reasoning patterns via tool-invocation feedback; and (2) a multi-tool self-critic RL algorithm with hierarchical reward design, which reinforces reward understanding and promotes effective tool collaboration. Experimental analyses on over 10 challenging reasoning benchmarks highlight the effectiveness and efficiency of Tool-Star. The code is available at https://github.com/dongguanting/Tool-Star.

Towards Accurate and Interpretable Neuroblastoma Diagnosis via Contrastive Multi-scale Pathological Image Analysis

Neuroblastoma, adrenal-derived, is among the most common pediatric solid malignancies, characterized by significant clinical heterogeneity. Timely and accurate pathological diagnosis from hematoxylin and eosin-stained whole slide images is critical for patient prognosis. However, current diagnostic practices primarily rely on subjective manual examination by pathologists, leading to inconsistent accuracy. Existing automated whole slide image classification methods encounter challenges such as poor interpretability, limited feature extraction capabilities, and high computational costs, restricting their practical clinical deployment. To overcome these limitations, we propose CMSwinKAN, a contrastive-learning-based multi-scale feature fusion model tailored for pathological image classification, which enhances the Swin Transformer architecture by integrating a Kernel Activation Network within its multilayer perceptron and classification head modules, significantly improving both interpretability and accuracy. By fusing multi-scale features and leveraging contrastive learning strategies, CMSwinKAN mimics clinicians' comprehensive approach, effectively capturing global and local tissue characteristics. Additionally, we introduce a heuristic soft voting mechanism guided by clinical insights to seamlessly bridge patch-level predictions to whole slide image-level classifications. We validate CMSwinKAN on the PpNTs dataset, which was collaboratively established with our partner hospital and the publicly accessible BreakHis dataset. Results demonstrate that CMSwinKAN performs better than existing state-of-the-art pathology-specific models pre-trained on large datasets. Our source code is available at https://github.com/JSLiam94/CMSwinKAN.

EmbodiedAgent: A Scalable Hierarchical Approach to Overcome Practical Challenge in Multi-Robot Control

This paper introduces EmbodiedAgent, a hierarchical framework for heterogeneous multi-robot control. EmbodiedAgent addresses critical limitations of hallucination in impractical tasks. Our approach integrates a next-action prediction paradigm with a structured memory system to decompose tasks into executable robot skills while dynamically validating actions against environmental constraints. We present MultiPlan+, a dataset of more than 18,000 annotated planning instances spanning 100 scenarios, including a subset of impractical cases to mitigate hallucination. To evaluate performance, we propose the Robot Planning Assessment Schema (RPAS), combining automated metrics with LLM-aided expert grading. Experiments demonstrate EmbodiedAgent's superiority over state-of-the-art models, achieving 71.85% RPAS score. Real-world validation in an office service task highlights its ability to coordinate heterogeneous robots for long-horizon objectives.

VADMamba: Exploring State Space Models for Fast Video Anomaly Detection

Video anomaly detection (VAD) methods are mostly CNN-based or Transformer-based, achieving impressive results, but the focus on detection accuracy often comes at the expense of inference speed. The emergence of state space models in computer vision, exemplified by the Mamba model, demonstrates improved computational efficiency through selective scans and showcases the great potential for long-range modeling. Our study pioneers the application of Mamba to VAD, dubbed VADMamba, which is based on multi-task learning for frame prediction and optical flow reconstruction. Specifically, we propose the VQ-Mamba Unet (VQ-MaU) framework, which incorporates a Vector Quantization (VQ) layer and Mamba-based Non-negative Visual State Space (NVSS) block. Furthermore, two individual VQ-MaU networks separately predict frames and reconstruct corresponding optical flows, further boosting accuracy through a clip-level fusion evaluation strategy. Experimental results validate the efficacy of the proposed VADMamba across three benchmark datasets, demonstrating superior performance in inference speed compared to previous work. Code is available at https://github.com/jLooo/VADMamba.

Can Multi-modal (reasoning) LLMs work as deepfake detectors?

Deepfake detection remains a critical challenge in the era of advanced generative models, particularly as synthetic media becomes more sophisticated. In this study, we explore the potential of state of the art multi-modal (reasoning) large language models (LLMs) for deepfake image detection such as (OpenAI O1/4o, Gemini thinking Flash 2, Deepseek Janus, Grok 3, llama 3.2, Qwen 2/2.5 VL, Mistral Pixtral, Claude 3.5/3.7 sonnet) . We benchmark 12 latest multi-modal LLMs against traditional deepfake detection methods across multiple datasets, including recently published real-world deepfake imagery. To enhance performance, we employ prompt tuning and conduct an in-depth analysis of the models' reasoning pathways to identify key contributing factors in their decision-making process. Our findings indicate that best multi-modal LLMs achieve competitive performance with promising generalization ability with zero shot, even surpass traditional deepfake detection pipelines in out-of-distribution datasets while the rest of the LLM families performs extremely disappointing with some worse than random guess. Furthermore, we found newer model version and reasoning capabilities does not contribute to performance in such niche tasks of deepfake detection while model size do help in some cases. This study highlights the potential of integrating multi-modal reasoning in future deepfake detection frameworks and provides insights into model interpretability for robustness in real-world scenarios.

APF+: Boosting adaptive-potential function reinforcement learning methods with a W-shaped network for high-dimensional games

Studies in reward shaping for reinforcement learning (RL) have flourished in recent years due to its ability to speed up training. Our previous work proposed an adaptive potential function (APF) and showed that APF can accelerate the Q-learning with a Multi-layer Perceptron algorithm in the low-dimensional domain. This paper proposes to extend APF with an encoder (APF+) for RL state representation, allowing applying APF to the pixel-based Atari games using a state-encoding method that projects high-dimensional game's pixel frames to low-dimensional embeddings. We approach by designing the state-representation encoder as a W-shaped network (W-Net), by using which we are able to encode both the background as well as the moving entities in the game frames. Specifically, the embeddings derived from the pre-trained W-Net consist of two latent vectors: One represents the input state, and the other represents the deviation of the input state's representation from itself. We then incorporate W-Net into APF to train a downstream Dueling Deep Q-Network (DDQN), obtain the APF-WNet-DDQN, and demonstrate its effectiveness in Atari game-playing tasks. To evaluate the APF+W-Net module in such high-dimensional tasks, we compare with two types of baseline methods: (i) the basic DDQN; and (ii) two encoder-replaced APF-DDQN methods where we replace W-Net by (a) an unsupervised state representation method called Spatiotemporal Deep Infomax (ST-DIM) and (b) a ground truth state representation provided by the Atari Annotated RAM Interface (ARI). The experiment results show that out of 20 Atari games, APF-WNet-DDQN outperforms DDQN (14/20 games) and APF-STDIM-DDQN (13/20 games) significantly. In comparison against the APF-ARI-DDQN which employs embeddings directly of the detailed game-internal state information, the APF-WNet-DDQN achieves a comparable performance.

MMLNB: Multi-Modal Learning for Neuroblastoma Subtyping Classification Assisted with Textual Description Generation

Neuroblastoma (NB), a leading cause of childhood cancer mortality, exhibits significant histopathological variability, necessitating precise subtyping for accurate prognosis and treatment. Traditional diagnostic methods rely on subjective evaluations that are time-consuming and inconsistent. To address these challenges, we introduce MMLNB, a multi-modal learning (MML) model that integrates pathological images with generated textual descriptions to improve classification accuracy and interpretability. The approach follows a two-stage process. First, we fine-tune a Vision-Language Model (VLM) to enhance pathology-aware text generation. Second, the fine-tuned VLM generates textual descriptions, using a dual-branch architecture to independently extract visual and textual features. These features are fused via Progressive Robust Multi-Modal Fusion (PRMF) Block for stable training. Experimental results show that the MMLNB model is more accurate than the single modal model. Ablation studies demonstrate the importance of multi-modal fusion, fine-tuning, and the PRMF mechanism. This research creates a scalable AI-driven framework for digital pathology, enhancing reliability and interpretability in NB subtyping classification. Our source code is available at https://github.com/HovChen/MMLNB.