Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China
Abstract:We propose a deep learning-based approach that integrates MRI sequence parameters to improve the accuracy and generalizability of quantitative image synthesis from clinical weighted MRI. Our physics-driven neural network embeds MRI sequence parameters -- repetition time (TR), echo time (TE), and inversion time (TI) -- directly into the model via parameter embedding, enabling the network to learn the underlying physical principles of MRI signal formation. The model takes conventional T1-weighted, T2-weighted, and T2-FLAIR images as input and synthesizes T1, T2, and proton density (PD) quantitative maps. Trained on healthy brain MR images, it was evaluated on both internal and external test datasets. The proposed method achieved high performance with PSNR values exceeding 34 dB and SSIM values above 0.92 for all synthesized parameter maps. It outperformed conventional deep learning models in accuracy and robustness, including data with previously unseen brain structures and lesions. Notably, our model accurately synthesized quantitative maps for these unseen pathological regions, highlighting its superior generalization capability. Incorporating MRI sequence parameters via parameter embedding allows the neural network to better learn the physical characteristics of MR signals, significantly enhancing the performance and reliability of quantitative MRI synthesis. This method shows great potential for accelerating qMRI and improving its clinical utility.
Abstract:Combining sparse IMUs and a monocular camera is a new promising setting to perform real-time human motion capture. This paper proposes a diffusion-based solution to learn human motion priors and fuse the two modalities of signals together seamlessly in a unified framework. By delicately considering the characteristics of the two signals, the sequential visual information is considered as a whole and transformed into a condition embedding, while the inertial measurement is concatenated with the noisy body pose frame by frame to construct a sequential input for the diffusion model. Firstly, we observe that the visual information may be unavailable in some frames due to occlusions or subjects moving out of the camera view. Thus incorporating the sequential visual features as a whole to get a single feature embedding is robust to the occasional degenerations of visual information in those frames. On the other hand, the IMU measurements are robust to occlusions and always stable when signal transmission has no problem. So incorporating them frame-wisely could better explore the temporal information for the system. Experiments have demonstrated the effectiveness of the system design and its state-of-the-art performance in pose estimation compared with the previous works. Our codes are available for research at https://shaohua-pan.github.io/diffcap-page.
Abstract:The emergence of GPT-4o-like large multimodal models (LMMs) has raised the exploration of integrating text, vision, and speech modalities to support more flexible multimodal interaction. Existing LMMs typically concatenate representation of modalities along the sequence dimension and feed them into a large language model (LLM) backbone. While sequence-dimension concatenation is straightforward for modality integration, it often relies heavily on large-scale data to learn modality alignments. In this paper, we aim to model the relationships between modalities more purposefully, thereby achieving more efficient and flexible modality alignments. To this end, we propose Stream-Omni, a large language-vision-speech model with efficient modality alignments, which can simultaneously support interactions under various modality combinations. Stream-Omni employs LLM as the backbone and aligns the vision and speech to the text based on their relationships. For vision that is semantically complementary to text, Stream-Omni uses sequence-dimension concatenation to achieve vision-text alignment. For speech that is semantically consistent with text, Stream-Omni introduces a CTC-based layer-dimension mapping to achieve speech-text alignment. In this way, Stream-Omni can achieve modality alignments with less data (especially speech), enabling the transfer of text capabilities to other modalities. Experiments on various benchmarks demonstrate that Stream-Omni achieves strong performance on visual understanding, speech interaction, and vision-grounded speech interaction tasks. Owing to the layer-dimensional mapping, Stream-Omni can simultaneously provide intermediate text outputs (such as ASR transcriptions and model responses) during speech interaction, offering users a comprehensive multimodal experience.
Abstract:The acquisition of agentic capabilities has transformed LLMs from "knowledge providers" to "action executors", a trend that while expanding LLMs' capability boundaries, significantly increases their susceptibility to malicious use. Previous work has shown that current LLM-based agents execute numerous malicious tasks even without being attacked, indicating a deficiency in agentic use safety alignment during the post-training phase. To address this gap, we propose AgentAlign, a novel framework that leverages abstract behavior chains as a medium for safety alignment data synthesis. By instantiating these behavior chains in simulated environments with diverse tool instances, our framework enables the generation of highly authentic and executable instructions while capturing complex multi-step dynamics. The framework further ensures model utility by proportionally synthesizing benign instructions through non-malicious interpretations of behavior chains, precisely calibrating the boundary between helpfulness and harmlessness. Evaluation results on AgentHarm demonstrate that fine-tuning three families of open-source models using our method substantially improves their safety (35.8% to 79.5% improvement) while minimally impacting or even positively enhancing their helpfulness, outperforming various prompting methods. The dataset and code have both been open-sourced.
Abstract:Spatial relation reasoning is a crucial task for multimodal large language models (MLLMs) to understand the objective world. However, current benchmarks have issues like relying on bounding boxes, ignoring perspective substitutions, or allowing questions to be answered using only the model's prior knowledge without image understanding. To address these issues, we introduce SpatialMQA, a human-annotated spatial relation reasoning benchmark based on COCO2017, which enables MLLMs to focus more on understanding images in the objective world. To ensure data quality, we design a well-tailored annotation procedure, resulting in SpatialMQA consisting of 5,392 samples. Based on this benchmark, a series of closed- and open-source MLLMs are implemented and the results indicate that the current state-of-the-art MLLM achieves only 48.14% accuracy, far below the human-level accuracy of 98.40%. Extensive experimental analyses are also conducted, suggesting the future research directions. The benchmark and codes are available at https://github.com/ziyan-xiaoyu/SpatialMQA.git.
Abstract:Real-time, intelligent, and natural speech interaction is an essential part of the next-generation human-computer interaction. Recent advancements have showcased the potential of building intelligent spoken chatbots based on large language models (LLMs). In this paper, we introduce LLaMA-Omni 2, a series of speech language models (SpeechLMs) ranging from 0.5B to 14B parameters, capable of achieving high-quality real-time speech interaction. LLaMA-Omni 2 is built upon the Qwen2.5 series models, integrating a speech encoder and an autoregressive streaming speech decoder. Despite being trained on only 200K multi-turn speech dialogue samples, LLaMA-Omni 2 demonstrates strong performance on several spoken question answering and speech instruction following benchmarks, surpassing previous state-of-the-art SpeechLMs like GLM-4-Voice, which was trained on millions of hours of speech data.
Abstract:Co-speech gesture generation enhances human-computer interaction realism through speech-synchronized gesture synthesis. However, generating semantically meaningful gestures remains a challenging problem. We propose SARGes, a novel framework that leverages large language models (LLMs) to parse speech content and generate reliable semantic gesture labels, which subsequently guide the synthesis of meaningful co-speech gestures.First, we constructed a comprehensive co-speech gesture ethogram and developed an LLM-based intent chain reasoning mechanism that systematically parses and decomposes gesture semantics into structured inference steps following ethogram criteria, effectively guiding LLMs to generate context-aware gesture labels. Subsequently, we constructed an intent chain-annotated text-to-gesture label dataset and trained a lightweight gesture label generation model, which then guides the generation of credible and semantically coherent co-speech gestures. Experimental results demonstrate that SARGes achieves highly semantically-aligned gesture labeling (50.2% accuracy) with efficient single-pass inference (0.4 seconds). The proposed method provides an interpretable intent reasoning pathway for semantic gesture synthesis.
Abstract:High-density planting is a widely adopted strategy to enhance maize productivity, yet it introduces challenges such as increased interplant competition and shading, which can limit light capture and overall yield potential. In response, some maize plants naturally reorient their canopies to optimize light capture, a process known as canopy reorientation. Understanding this adaptive response and its impact on light capture is crucial for maximizing agricultural yield potential. This study introduces an end-to-end framework that integrates realistic 3D reconstructions of field-grown maize with photosynthetically active radiation (PAR) modeling to assess the effects of phyllotaxy and planting density on light interception. In particular, using 3D point clouds derived from field data, virtual fields for a diverse set of maize genotypes were constructed and validated against field PAR measurements. Using this framework, we present detailed analyses of the impact of canopy orientations, plant and row spacings, and planting row directions on PAR interception throughout a typical growing season. Our findings highlight significant variations in light interception efficiency across different planting densities and canopy orientations. By elucidating the relationship between canopy architecture and light capture, this study offers valuable guidance for optimizing maize breeding and cultivation strategies across diverse agricultural settings.
Abstract:Audio-driven human gesture synthesis is a crucial task with broad applications in virtual avatars, human-computer interaction, and creative content generation. Despite notable progress, existing methods often produce gestures that are coarse, lack expressiveness, and fail to fully align with audio semantics. To address these challenges, we propose ExGes, a novel retrieval-enhanced diffusion framework with three key designs: (1) a Motion Base Construction, which builds a gesture library using training dataset; (2) a Motion Retrieval Module, employing constrative learning and momentum distillation for fine-grained reference poses retreiving; and (3) a Precision Control Module, integrating partial masking and stochastic masking to enable flexible and fine-grained control. Experimental evaluations on BEAT2 demonstrate that ExGes reduces Fr\'echet Gesture Distance by 6.2\% and improves motion diversity by 5.3\% over EMAGE, with user studies revealing a 71.3\% preference for its naturalness and semantic relevance. Code will be released upon acceptance.
Abstract:Large language models (LLMs), with their powerful generative capabilities and vast knowledge, empower various tasks in everyday life. However, these abilities are primarily concentrated in high-resource languages, leaving low-resource languages with weaker generative capabilities and relatively limited knowledge. Enhancing the multilingual capabilities of LLMs is therefore crucial for serving over 100 linguistic communities worldwide. An intuitive approach to enhance the multilingual capabilities would be to construct instruction data for various languages, but constructing instruction data for over 100 languages is prohibitively costly. In this paper, we introduce BayLing 2, which efficiently transfers generative capabilities and knowledge from high-resource languages to low-resource languages through language alignment. To achieve this, we constructed a dataset of 3.2 million instructions, comprising high-resource language instructions (Chinese and English) and cross-lingual instructions for 100+ languages and performed instruction tuning based on the dataset to facilitate the capability transfer between languages. Using Llama as the foundation model, we developed BayLing-2-7B, BayLing-2-13B, and BayLing-3-8B, and conducted a comprehensive evaluation of BayLing. For multilingual translation across 100+ languages, BayLing shows superior performance compared to open-source models of similar scale. For multilingual knowledge and understanding benchmarks, BayLing achieves significant improvements across over 20 low-resource languages, demonstrating its capability of effective knowledge transfer from high-resource to low-resource languages. Furthermore, results on English benchmarks indicate that BayLing maintains high performance in highresource languages while enhancing the performance in low-resource languages. Demo, homepage, code and models of BayLing are available.