Crowdsourcing platforms have transformed distributed problem-solving, yet quality control remains a persistent challenge. Traditional quality control measures, such as prescreening workers and refining instructions, often focus solely on optimizing economic output. This paper explores just-in-time AI interventions to enhance both labeling quality and domain-specific knowledge among crowdworkers. We introduce LabelAId, an advanced inference model combining Programmatic Weak Supervision (PWS) with FT-Transformers to infer label correctness based on user behavior and domain knowledge. Our technical evaluation shows that our LabelAId pipeline consistently outperforms state-of-the-art ML baselines, improving mistake inference accuracy by 36.7% with 50 downstream samples. We then implemented LabelAId into Project Sidewalk, an open-source crowdsourcing platform for urban accessibility. A between-subjects study with 34 participants demonstrates that LabelAId significantly enhances label precision without compromising efficiency while also increasing labeler confidence. We discuss LabelAId's success factors, limitations, and its generalizability to other crowdsourced science domains.
Health acoustic sounds such as coughs and breaths are known to contain useful health signals with significant potential for monitoring health and disease, yet are underexplored in the medical machine learning community. The existing deep learning systems for health acoustics are often narrowly trained and evaluated on a single task, which is limited by data and may hinder generalization to other tasks. To mitigate these gaps, we develop HeAR, a scalable self-supervised learning-based deep learning system using masked autoencoders trained on a large dataset of 313 million two-second long audio clips. Through linear probes, we establish HeAR as a state-of-the-art health audio embedding model on a benchmark of 33 health acoustic tasks across 6 datasets. By introducing this work, we hope to enable and accelerate further health acoustics research.
Advances in artificial intelligence (AI) have achieved expert-level performance in medical imaging applications. Notably, self-supervised vision-language foundation models can detect a broad spectrum of pathologies without relying on explicit training annotations. However, it is crucial to ensure that these AI models do not mirror or amplify human biases, thereby disadvantaging historically marginalized groups such as females or Black patients. The manifestation of such biases could systematically delay essential medical care for certain patient subgroups. In this study, we investigate the algorithmic fairness of state-of-the-art vision-language foundation models in chest X-ray diagnosis across five globally-sourced datasets. Our findings reveal that compared to board-certified radiologists, these foundation models consistently underdiagnose marginalized groups, with even higher rates seen in intersectional subgroups, such as Black female patients. Such demographic biases present over a wide range of pathologies and demographic attributes. Further analysis of the model embedding uncovers its significant encoding of demographic information. Deploying AI systems with these biases in medical imaging can intensify pre-existing care disparities, posing potential challenges to equitable healthcare access and raising ethical questions about their clinical application.
An accurate differential diagnosis (DDx) is a cornerstone of medical care, often reached through an iterative process of interpretation that combines clinical history, physical examination, investigations and procedures. Interactive interfaces powered by Large Language Models (LLMs) present new opportunities to both assist and automate aspects of this process. In this study, we introduce an LLM optimized for diagnostic reasoning, and evaluate its ability to generate a DDx alone or as an aid to clinicians. 20 clinicians evaluated 302 challenging, real-world medical cases sourced from the New England Journal of Medicine (NEJM) case reports. Each case report was read by two clinicians, who were randomized to one of two assistive conditions: either assistance from search engines and standard medical resources, or LLM assistance in addition to these tools. All clinicians provided a baseline, unassisted DDx prior to using the respective assistive tools. Our LLM for DDx exhibited standalone performance that exceeded that of unassisted clinicians (top-10 accuracy 59.1% vs 33.6%, [p = 0.04]). Comparing the two assisted study arms, the DDx quality score was higher for clinicians assisted by our LLM (top-10 accuracy 51.7%) compared to clinicians without its assistance (36.1%) (McNemar's Test: 45.7, p < 0.01) and clinicians with search (44.4%) (4.75, p = 0.03). Further, clinicians assisted by our LLM arrived at more comprehensive differential lists than those without its assistance. Our study suggests that our LLM for DDx has potential to improve clinicians' diagnostic reasoning and accuracy in challenging cases, meriting further real-world evaluation for its ability to empower physicians and widen patients' access to specialist-level expertise.
Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical practice requires addressing challenges of generalization across devices and weak or ambiguous correlations between the measured signals and an individual's mental health. To address these challenges, we take a novel approach that leverages large language models (LLMs) to synthesize clinically useful insights from multi-sensor data. We develop chain of thought prompting methods that use LLMs to generate reasoning about how trends in data such as step count and sleep relate to conditions like depression and anxiety. We first demonstrate binary depression classification with LLMs achieving accuracies of 61.1% which exceed the state of the art. While it is not robust for clinical use, this leads us to our key finding: even more impactful and valued than classification is a new human-AI collaboration approach in which clinician experts interactively query these tools and combine their domain expertise and context about the patient with AI generated reasoning to support clinical decision-making. We find models like GPT-4 correctly reference numerical data 75% of the time, and clinician participants express strong interest in using this approach to interpret self-tracking data.
Recent advances in supervised deep learning techniques have demonstrated the possibility to remotely measure human physiological vital signs (e.g., photoplethysmograph, heart rate) just from facial videos. However, the performance of these methods heavily relies on the availability and diversity of real labeled data. Yet, collecting large-scale real-world data with high-quality labels is typically challenging and resource intensive, which also raises privacy concerns when storing personal bio-metric data. Synthetic video-based datasets (e.g., SCAMPS \cite{mcduff2022scamps}) with photo-realistic synthesized avatars are introduced to alleviate the issues while providing high-quality synthetic data. However, there exists a significant gap between synthetic and real-world data, which hinders the generalization of neural models trained on these synthetic datasets. In this paper, we proposed several measures to add real-world noise to synthetic physiological signals and corresponding facial videos. We experimented with individual and combined augmentation methods and evaluated our framework on three public real-world datasets. Our results show that we were able to reduce the average MAE from 6.9 to 2.0.
Large language models (LLMs) have shown remarkable abilities to generate code, however their ability to develop software for embedded systems, which requires cross-domain knowledge of hardware and software has not been studied. In this paper we systematically evaluate leading LLMs (GPT-3.5, GPT-4, PaLM 2) to assess their performance for embedded system development, study how human programmers interact with these tools, and develop an AI-based software engineering workflow for building embedded systems. We develop an an end-to-end hardware-in-the-loop evaluation platform for verifying LLM generated programs using sensor actuator pairs. We compare all three models with N=450 experiments and find surprisingly that GPT-4 especially shows an exceptional level of cross-domain understanding and reasoning, in some cases generating fully correct programs from a single prompt. In N=50 trials, GPT-4 produces functional I2C interfaces 66% of the time. GPT-4 also produces register-level drivers, code for LoRa communication, and context-specific power optimizations for an nRF52 program resulting in over 740x current reduction to 12.2 uA. We also characterize the models' limitations to develop a generalizable workflow for using LLMs in embedded system development. We evaluate the workflow with 15 users including novice and expert programmers. We find that our workflow improves productivity for all users and increases the success rate for building a LoRa environmental sensor from 25% to 100%, including for users with zero hardware or C/C++ experience.
Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models be grounded in numerical data (e.g., vital signs, laboratory values in clinical domains; steps, movement in the wellness domain) that is not easily or readily expressed as text in existing training corpus. We demonstrate that with only few-shot tuning, a large language model is capable of grounding various physiological and behavioral time-series data and making meaningful inferences on numerous health tasks for both clinical and wellness contexts. Using data from wearable and medical sensor recordings, we evaluate these capabilities on the tasks of cardiac signal analysis, physical activity recognition, metabolic calculation (e.g., calories burned), and estimation of stress reports and mental health screeners.
Machine learning models for camera-based physiological measurement can have weak generalization due to a lack of representative training data. Body motion is one of the most significant sources of noise when attempting to recover the subtle cardiac pulse from a video. We explore motion transfer as a form of data augmentation to introduce motion variation while preserving physiological changes. We adapt a neural video synthesis approach to augment videos for the task of remote photoplethysmography (PPG) and study the effects of motion augmentation with respect to 1) the magnitude and 2) the type of motion. After training on motion-augmented versions of publicly available datasets, the presented inter-dataset results on five benchmark datasets show improvements of up to 75% over existing state-of-the-art results. Our findings illustrate the utility of motion transfer as a data augmentation technique for improving the generalization of models for camera-based physiological sensing. We release our code and pre-trained models for using motion transfer as a data augmentation technique on our project page: https://motion-matters.github.io/