Curated datasets for healthcare are often limited due to the need of human annotations from experts. In this paper, we present MedEval, a multi-level, multi-task, and multi-domain medical benchmark to facilitate the development of language models for healthcare. MedEval is comprehensive and consists of data from several healthcare systems and spans 35 human body regions from 8 examination modalities. With 22,779 collected sentences and 21,228 reports, we provide expert annotations at multiple levels, offering a granular potential usage of the data and supporting a wide range of tasks. Moreover, we systematically evaluated 10 generic and domain-specific language models under zero-shot and finetuning settings, from domain-adapted baselines in healthcare to general-purposed state-of-the-art large language models (e.g., ChatGPT). Our evaluations reveal varying effectiveness of the two categories of language models across different tasks, from which we notice the importance of instruction tuning for few-shot usage of large language models. Our investigation paves the way toward benchmarking language models for healthcare and provides valuable insights into the strengths and limitations of adopting large language models in medical domains, informing their practical applications and future advancements.
Lead sheets have become commonplace in generative music research, being used as an initial compressed representation for downstream tasks like multitrack music generation and automatic arrangement. Despite this, researchers have often fallen back on deterministic reduction methods (such as the skyline algorithm) to generate lead sheets when seeking paired lead sheets and full scores, with little attention being paid toward the quality of the lead sheets themselves and how they accurately reflect their orchestrated counterparts. To address these issues, we propose the problem of conditional lead sheet generation (i.e. generating a lead sheet given its full score version), and show that this task can be formulated as an unsupervised music compression task, where the lead sheet represents a compressed latent version of the score. We introduce a novel model, called Lead-AE, that models the lead sheets as a discrete subselection of the original sequence, using a differentiable top-k operator to allow for controllable local sparsity constraints. Across both automatic proxy tasks and direct human evaluations, we find that our method improves upon the established deterministic baseline and produces coherent reductions of large multitrack scores.
We study data distillation for auto-regressive machine learning tasks, where the input and output have a strict left-to-right causal structure. More specifically, we propose Farzi, which summarizes an event sequence dataset into a small number of synthetic sequences -- Farzi Data -- which are optimized to maintain (if not improve) model performance compared to training on the full dataset. Under the hood, Farzi conducts memory-efficient data distillation by (i) deriving efficient reverse-mode differentiation of the Adam optimizer by leveraging Hessian-Vector Products; and (ii) factorizing the high-dimensional discrete event-space into a latent-space which provably promotes implicit regularization. Empirically, for sequential recommendation and language modeling tasks, we are able to achieve 98-120% of downstream full-data performance when training state-of-the-art models on Farzi Data of size as little as 0.1% of the original dataset. Notably, being able to train better models with significantly less data sheds light on the design of future large auto-regressive models, and opens up new opportunities to further scale up model and data sizes.
We propose SelfVC, a training strategy to iteratively improve a voice conversion model with self-synthesized examples. Previous efforts on voice conversion focus on explicitly disentangling speech representations to separately encode speaker characteristics and linguistic content. However, disentangling speech representations to capture such attributes using task-specific loss terms can lead to information loss by discarding finer nuances of the original signal. In this work, instead of explicitly disentangling attributes with loss terms, we present a framework to train a controllable voice conversion model on entangled speech representations derived from self-supervised learning and speaker verification models. First, we develop techniques to derive prosodic information from the audio signal and SSL representations to train predictive submodules in the synthesis model. Next, we propose a training strategy to iteratively improve the synthesis model for voice conversion, by creating a challenging training objective using self-synthesized examples. In this training approach, the current state of the synthesis model is used to generate voice-converted variations of an utterance, which serve as inputs for the reconstruction task, ensuring a continuous and purposeful refinement of the model. We demonstrate that incorporating such self-synthesized examples during training improves the speaker similarity of generated speech as compared to a baseline voice conversion model trained solely on heuristically perturbed inputs. SelfVC is trained without any text and is applicable to a range of tasks such as zero-shot voice conversion, cross-lingual voice conversion, and controllable speech synthesis with pitch and pace modifications. SelfVC achieves state-of-the-art results in zero-shot voice conversion on metrics evaluating naturalness, speaker similarity, and intelligibility of synthesized audio.
Recently, there has been an emergence of employing LLM-powered agents as believable human proxies, based on their remarkable decision-making capability. However, existing studies mainly focus on simulating human dialogue. Human non-verbal behaviors, such as item clicking in recommender systems, although implicitly exhibiting user preferences and could enhance the modeling of users, have not been deeply explored. The main reasons lie in the gap between language modeling and behavior modeling, as well as the incomprehension of LLMs about user-item relations. To address this issue, we propose AgentCF for simulating user-item interactions in recommender systems through agent-based collaborative filtering. We creatively consider not only users but also items as agents, and develop a collaborative learning approach that optimizes both kinds of agents together. Specifically, at each time step, we first prompt the user and item agents to interact autonomously. Then, based on the disparities between the agents' decisions and real-world interaction records, user and item agents are prompted to reflect on and adjust the misleading simulations collaboratively, thereby modeling their two-sided relations. The optimized agents can also propagate their preferences to other agents in subsequent interactions, implicitly capturing the collaborative filtering idea. Overall, the optimized agents exhibit diverse interaction behaviors within our framework, including user-item, user-user, item-item, and collective interactions. The results show that these agents can demonstrate personalized behaviors akin to those of real-world individuals, sparking the development of next-generation user behavior simulation.
Medical image classification is a critical problem for healthcare, with the potential to alleviate the workload of doctors and facilitate diagnoses of patients. However, two challenges arise when deploying deep learning models to real-world healthcare applications. First, neural models tend to learn spurious correlations instead of desired features, which could fall short when generalizing to new domains (e.g., patients with different ages). Second, these black-box models lack interpretability. When making diagnostic predictions, it is important to understand why a model makes a decision for trustworthy and safety considerations. In this paper, to address these two limitations, we propose a new paradigm to build robust and interpretable medical image classifiers with natural language concepts. Specifically, we first query clinical concepts from GPT-4, then transform latent image features into explicit concepts with a vision-language model. We systematically evaluate our method on eight medical image classification datasets to verify its effectiveness. On challenging datasets with strong confounding factors, our method can mitigate spurious correlations thus substantially outperform standard visual encoders and other baselines. Finally, we show how classification with a small number of concepts brings a level of interpretability for understanding model decisions through case studies in real medical data.
State-of-the-art sequential recommendation relies heavily on self-attention-based recommender models. Yet such models are computationally expensive and often too slow for real-time recommendation. Furthermore, the self-attention operation is performed at a sequence-level, thereby making low-cost incremental inference challenging. Inspired by recent advances in efficient language modeling, we propose linear recurrent units for sequential recommendation (LRURec). Similar to recurrent neural networks, LRURec offers rapid inference and can achieve incremental inference on sequential inputs. By decomposing the linear recurrence operation and designing recursive parallelization in our framework, LRURec provides the additional benefits of reduced model size and parallelizable training. Moreover, we optimize the architecture of LRURec by implementing a series of modifications to address the lack of non-linearity and improve training dynamics. To validate the effectiveness of our proposed LRURec, we conduct extensive experiments on multiple real-world datasets and compare its performance against state-of-the-art sequential recommenders. Experimental results demonstrate the effectiveness of LRURec, which consistently outperforms baselines by a significant margin. Results also highlight the efficiency of LRURec with our parallelized training paradigm and fast inference on long sequences, showing its potential to further enhance user experience in sequential recommendation.
Alignment serves as an important step to steer large language models (LLMs) towards human preferences. In this paper, we explore contrastive post-training techniques for alignment by automatically constructing preference pairs from multiple models of varying strengths (e.g., InstructGPT, ChatGPT and GPT-4). We carefully compare the contrastive techniques of SLiC and DPO to SFT baselines and find that DPO provides a step-function improvement even after continueing SFT saturates. We also explore a data curriculum learning scheme for contrastive post-training, which starts by learning from "easier" pairs and transitioning to "harder" ones, which further improves alignment. Finally, we scale up our experiments to train with more data and larger models like Orca. Remarkably, contrastive post-training further improves the performance of Orca, already a state-of-the-art instruction learning model tuned with GPT-4 outputs, to exceed that of ChatGPT.
Deep Generative AI has been a long-standing essential topic in the machine learning community, which can impact a number of application areas like text generation and computer vision. The major paradigm to train a generative model is maximum likelihood estimation, which pushes the learner to capture and approximate the target data distribution by decreasing the divergence between the model distribution and the target distribution. This formulation successfully establishes the objective of generative tasks, while it is incapable of satisfying all the requirements that a user might expect from a generative model. Reinforcement learning, serving as a competitive option to inject new training signals by creating new objectives that exploit novel signals, has demonstrated its power and flexibility to incorporate human inductive bias from multiple angles, such as adversarial learning, hand-designed rules and learned reward model to build a performant model. Thereby, reinforcement learning has become a trending research field and has stretched the limits of generative AI in both model design and application. It is reasonable to summarize and conclude advances in recent years with a comprehensive review. Although there are surveys in different application areas recently, this survey aims to shed light on a high-level review that spans a range of application areas. We provide a rigorous taxonomy in this area and make sufficient coverage on various models and applications. Notably, we also surveyed the fast-developing large language model area. We conclude this survey by showing the potential directions that might tackle the limit of current models and expand the frontiers for generative AI.
Reinforcement learning serves as a potent tool for modeling dynamic user interests within recommender systems, garnering increasing research attention of late. However, a significant drawback persists: its poor data efficiency, stemming from its interactive nature. The training of reinforcement learning-based recommender systems demands expensive online interactions to amass adequate trajectories, essential for agents to learn user preferences. This inefficiency renders reinforcement learning-based recommender systems a formidable undertaking, necessitating the exploration of potential solutions. Recent strides in offline reinforcement learning present a new perspective. Offline reinforcement learning empowers agents to glean insights from offline datasets and deploy learned policies in online settings. Given that recommender systems possess extensive offline datasets, the framework of offline reinforcement learning aligns seamlessly. Despite being a burgeoning field, works centered on recommender systems utilizing offline reinforcement learning remain limited. This survey aims to introduce and delve into offline reinforcement learning within recommender systems, offering an inclusive review of existing literature in this domain. Furthermore, we strive to underscore prevalent challenges, opportunities, and future pathways, poised to propel research in this evolving field.