Medical Heuristic Learning: An LLM-Driven Framework for Interpretable and Auditable Clinical Decision Rules

Predictive modeling for clinical tabular data is central to clinical decision support and therefore requires not only strong predictive performance but also transparent decision logic. Although deep learning and tree-based ensemble methods can achieve high accuracy, their black-box nature remains a major obstacle to clinical deployment. This challenge is further compounded by common characteristics of medical data, including limited sample sizes, severe class imbalance, and feature evolution arising from changes in diagnostic criteria and clinical documentation. To address these issues, we propose Medical Heuristic Learning (MHL), an instantiation of the learning-beyond-gradients paradigm for clinical tabular prediction. Instead of relying on neural network weight updates, MHL uses a large language model (LLM)-driven workflow that integrates statistical probes, medical knowledge probes, rule synthesis, and code-level iterative refinement to optimize a deterministic and executable decision system. The resulting model is expressed not as opaque parameters, but as versioned pure-Python decision rules that are explicitly interpretable, fully auditable, and clinically grounded. MHL also supports continual learning by starting from previously validated rules and iteratively revising them using updated feature information under data drift or feature evolution. Comprehensive experiments on medical datasets show that MHL achieves performance comparable to state-of-the-art methods while maintaining strong behavior in small-sample and highly imbalanced settings. The results further indicate that this explicit rule update mechanism can help alleviate catastrophic forgetting under feature evolution. Overall, these findings suggest that non-gradient-based heuristic systems offer a transparent and adaptable alternative for high-stakes clinical decision support.

VideoWeaver: Evaluating and Evolving Skills for Agentic Long Video Generation

Recent agent frameworks such as Claude Code, Codex, and OpenClaw are strong at tool use and orchestration, but whether they can handle long video generation, a long-horizon multimodal task, remains underexplored. Unlike earlier video agents whose pipeline is handcrafted, these frameworks can build and refine their own workflows. We introduce VideoWeaver, an agent harness and benchmark that evaluates and evolves skills for long video generation, where an agent turns a single instruction into a long video by composing foundation skills into its own workflow rather than following a predefined pipeline. The benchmark has 16 task categories and 285 cases, with references spanning text, image, audio, video, and their combinations. Because errors can arise at any stage and not just in the final video, we propose an agent-as-judge that inspects both the execution trace and the final video, grounding its scores in evidence such as metadata and intermediate files. Using this feedback, we further design a skill evolution algorithm that refines and merges the agent's skills. Across multiple frameworks and models, we find that an explicit composition skill improves the generation process over using foundation skills alone, that skill evolution further improves output quality, and that performance varies notably across harness and model choices. The proposed agent-as-judge also aligns well with human judgments, especially on process metrics. Code and dataset is available at https://github.com/JianhuiWei7/VideoWeaver

Localizing Prompt Ambiguity in Large Language Models with Probe-Targeted Attribution

Prompt ambiguity is a common source of failure in large language models, but is difficult to localize because it is a latent property of the prompt, while existing attribution methods are designed to explain observable outputs such as logits or generated tokens. We introduce PRIG, a gradient attribution method that uses a probe logit to attribute latent ambiguity to token positions. Specifically, PRIG trains a linear probe to distinguish clear prompts from ambiguous prompts and attributes the probe score to earlier token representations in the residual stream. To enable token-level evaluation, we construct synthetic ambiguity datasets across coding, math, and writing by rewriting one task-critical sentence per prompt, and complement them with a human-written gold benchmark. In this setting, PRIG localizes ambiguous spans substantially better than gradient attribution baselines, achieving 0.840 AUROC on the combined synthetic benchmark and 0.891 AUROC on the gold set. It also outperforms GPT-5.4 on sentence-level ambiguity identification and retains useful signal out-of-domain. These results establish PRIG as a practical tool for identifying which parts of a prompt are ambiguous. More broadly, they suggest that latent prompt properties can be localized through intermediate representations, rather than through output-level attribution.

HD-DinoMoE: A Class-Aware Hierarchical Dual Mixture-of-Experts Network for Scleral Anomaly Segmentation in Complex Acquisition Scenarios

Traditional Chinese Medicine (TCM) ocular inspection provides empirical cues for assessing scleral surface anomalies, but its clinical use remains subjective and difficult to quantify. To support intelligent and quantifiable ocular inspection, this study presents the TCM-inspired Artificial Intelligence Ocular Auxiliary Diagnosis System (TAO) and focuses on pixel-level scleral surface anomaly segmentation. For clinical and user-acquired images affected by multi-source distributional discrepancies, diverse anomaly morphologies, and scleral specular reflection (SSR), we propose HD-DinoMoE, a class-aware hierarchical dual mixture-of-experts network. HD-DinoMoE combines class-aware dual-stream DINOv3 feature fusion with class-specific multi-expert decoding to segment Vessels, Yellow and Black Spots, and Blood Spots. A three-stage backbone-frozen routing strategy stabilizes dual-backbone adaptation; Progressive Confidence Penalty (PCP) Loss reduces high-confidence false positives and segmentation leakage in SSR regions; and Class-Aware Adaptive Sample Weighting (CA-ASW) balances sample- and class-level training contributions. We further construct the Multi-label Scleral Anomaly Segmentation Dataset (ML-SASD), a new benchmark with Clinical, Wild, and Mix settings and pixel-wise annotations for three anomaly categories. On ML-SASD-Mix, HD-DinoMoE achieves a mean Dice of 72.11% and a mean Intersection-over-Union of 58.44%, while maintaining favorable boundary localization and specular-region false-positive control. It also shows competitive generalization on the Vessels subset of the public SBVPI dataset. These results indicate that HD-DinoMoE provides a feasible segmentation solution for TAO under complex acquisition scenarios. The code and data access information are available at https://github.com/FX-CMX/HD-DinoMoE.

Investigating and Alleviating Harm Amplification in LLM Interactions

Large language models (LLMs) can serve as helpful assistants, yet they can equally function as harm amplifiers that enable malicious users to achieve harmful outcomes beyond their capabilities through extended interactions. This risk manifests along two axes, i.e., democratizing domain expertise that allows novices to produce specialized harmful content, and scaling harmful operations at volumes that manual effort cannot match. Existing works, however, often overlook how LLMs compound harm across multi-turn conversations. We introduce HarmAmp, a new benchmark for multi-turn harm amplification scenarios spanning twelve risk categories. Each scenario is grounded in real-world threats and satisfies rigorous criteria, i.e., substantive amplification, operational specificity, and multi-turn necessity. We further propose TrajSafe, a proactive monitor that anticipates harmful trajectories and intervenes through actions such as probing users' genuine intents and steering the models towards safer completion. Our extensive experiments demonstrate that TrajSafe significantly reduces the harmfulness incurred in multi-turn interactions while preserving a low over-refusal rate and the target model's general capabilities. Our work offers a promising paradigm to alleviate the nuanced safety risks in LLM interactions.

Depth from Dual Differential Defocus and Stereo Consensus

We introduce D^3S Consensus, a physics-based, closed-form algorithm that unifies depth-from-defocus (DfD) and stereo to achieve highly accurate depth estimation throughout an extended working range beyond the depth-of-field (DoF) of cameras. Given a pair of dual-defocus stereo images, the method estimates an overdetermined set of depth using a novel DfD theory, Dual Differential Defocus (D^3), and (S)tereo in a coupled fashion. It then picks the most confident depth prediction from the set by enforcing consensus between these physically independent cues to reject unreliable estimates. Analysis shows that D^3S achieves a comparable working range under the same error tolerance with 10x smaller baseline than previous triangulation-based depth estimation systems. This enables compact passive binocular rangefinders with substantially smaller form factors than conventional stereo and DfD designs. We demonstrate the first D^3S prototype with only 4 mm baseline and 12 mm EFL. It generates up to 900 x 1800-pixel depth maps with 1-cm mean absolute error over 0.3-1.64 m from a snapshot acquisition. This has surpassed the reported accuracy of certain commercially available stereo cameras with much larger form factors.

Non-Learning Low-Light Stereo Vision

We present a non-learning stereo framework for disparity estimation from severely noisy images. Using the Field of Junctions (FoJ), it retains coarse visual features stable under severe noise for cost volume construction while discarding fine textures inseparable from photon noise. The resulting structural information guides boundary-aware Semi-Global Matching (SGM) that dynamically adapts smoothness penalties to preserve true disparity discontinuities. The output is a sparse disparity map more accurate than those of recent stereo algorithms over unmasked pixels on widely-used benchmark datasets.

Learning to Route Languages for Multilingual Policy Optimization

Large language models~(LLMs) are trained on heterogeneous multilingual corpora, yet existing policy optimization methods often implicitly restrict each training question to a single response language or rely on a fixed dominant language for supervision. We propose language-routed policy optimization (LRPO), an online policy optimization framework that treats language as a selectable variable. LRPO elicits multilingual rollouts for each training question and integrates their relative quality into preference-based policy updates, increasing the diversity and informativeness of training signals under the fixed rollout budget. To adaptively determine which languages to explore during reinforcement learning, we introduce a trainable language router formulated as a multi-armed bandit, balancing exploration of underutilized languages with exploitation of more informative ones. Extensive experiments show that LRPO consistently improves multilingual performance, demonstrating that adaptive language routing enables effective cross-lingual knowledge exploitation for training. We release all the resources at https://github.com/Guochry/LRPO.

Synthetic Data Alone is Enough? Rethinking Data Scarcity in Pediatric Rare Disease Recognition

Children with rare genetic diseases often exhibit distinctive facial phenotypes, yet developing computer vision systems for early diagnosis remains challenging due to extreme data scarcity, privacy constraints, and limited data sharing in pediatric settings. These challenges not only hinder automated diagnosis but also restrict the availability of visual resources for clinical genetic counseling. While prior work has shown that synthetic data can augment real datasets and preserve phenotype-level semantics, it remains unclear whether synthetic data alone is sufficient for learning in ultra-low-resource pediatric settings. In this work, we study the synthetic-only regime for pediatric rare disease recognition. Under a controlled experimental setup, models are trained exclusively on phenotype-aware synthetic facial images at increasing scales. We find that synthetic-only training achieves performance comparable to real-data-only baselines at sufficient scale across multiple backbones, suggesting that high-fidelity synthetic data can approximate clinically meaningful distributions. These findings together further enable the use of synthetic pediatric facial images as privacy-preserving resources for genetic education and counseling, supporting clinician training and patient communication. Our results highlight the potential of computer vision to improve data efficiency and expand accessible visual tools in children's healthcare.

MemConflict: Evaluating Long-Term Memory Systems Under Memory Conflicts

Long-term memory systems enable conversational agents based on large language models (LLMs) to retain, retrieve, and apply user-specific information across multi-session interactions. However, existing evaluations mainly assess outcome-level performance or temporal updating, providing limited insight into how systems retrieve and rank temporally valid, factually correct, and contextually applicable memory evidence under conflicting alternatives. To address this gap, we propose MemConflict, a diagnostic framework that treats memory validity as a query-conditioned fitness-for-use problem. MemConflict formalizes dynamic, static, and conditional conflicts over temporal validity, factual correctness, and contextual applicability. It simulates controlled long-horizon histories from structured user profiles, introduces cross-session conflicts, and injects semantically similar distractors to create competition among memory candidates. The resulting multi-session dialogue benchmark supports black-box evaluation of final answers and white-box analysis of supporting-memory retrieval and ranking. Experiments on six representative long-term memory systems show uneven strengths across conflict types, with answer correctness often diverging from memory retrieval and ranking. Sensitivity analyses reveal that longer histories, distractors, implicit queries, and larger conflict distances degrade performance. Diagnostics show failures from missing supporting memories and ineffective use of retrieved memories. Collectively, MemConflict advances principled long-term memory governance through retrieval-aware, conflict-aware reliability assessment.