Learning Generalizable 3D Medical Image Representations from Mask-Guided Self-Supervision

Foundation models have transformed vision and language by learning general-purpose representations from large-scale unlabeled data, yet 3D medical imaging lacks analogous approaches. Existing self-supervised methods rely on low-level reconstruction or contrastive objectives that fail to capture the anatomical semantics critical for medical image analysis, limiting transfer to downstream tasks. We present MASS (MAsk-guided Self-Supervised learning), which treats in-context segmentation as the pretext task for learning general-purpose medical imaging representations. MASS's key insight is that automatically generated class-agnostic masks provide sufficient structural supervision for learning semantically rich representations. By training on thousands of diverse mask proposals spanning anatomical structures and pathological findings, MASS learns what semantically defines medical structures: the holistic combination of appearance, shape, spatial context, and anatomical relationships. We demonstrate effectiveness across data regimes: from small-scale pretraining on individual datasets (20-200 scans) to large-scale multi-modal pretraining on 5K CT, MRI, and PET volumes, all without annotations. MASS demonstrates: (i) few-shot segmentation on novel structures, (ii) matching full supervision with only 20-40\% labeled data while outperforming self-supervised baselines by over 20 in Dice score in low-data regimes, and (iii) frozen-encoder classification on unseen pathologies that matches full supervised training with thousands of samples. Mask-guided self-supervised pretraining captures broadly generalizable knowledge, opening a path toward 3D medical imaging foundation models without expert annotations. Code is available: https://github.com/Stanford-AIMI/MASS.

Structure-aware Prompt Adaptation from Seen to Unseen for Open-Vocabulary Compositional Zero-Shot Learning

The goal of Open-Vocabulary Compositional Zero-Shot Learning (OV-CZSL) is to recognize attribute-object compositions in the open-vocabulary setting, where compositions of both seen and unseen attributes and objects are evaluated. Recently, prompt tuning methods have demonstrated strong generalization capabilities in the closed setting, where only compositions of seen attributes and objects are evaluated, i.e., Compositional Zero-Shot Learning (CZSL). However, directly applying these methods to OV-CZSL may not be sufficient to generalize to unseen attributes, objects and their compositions, as it is limited to seen attributes and objects. Normally, when faced with unseen concepts, humans adopt analogies with seen concepts that have the similar semantics thereby inferring their meaning (e.g., "wet" and "damp", "shirt" and "jacket"). In this paper, we experimentally show that the distribution of semantically related attributes or objects tends to form consistent local structures in the embedding space. Based on the above structures, we propose Structure-aware Prompt Adaptation (SPA) method, which enables models to generalize from seen to unseen attributes and objects. Specifically, in the training stage, we design a Structure-aware Consistency Loss (SCL) that encourages the local structure's consistency of seen attributes and objects in each iteration. In the inference stage, we devise a Structure-guided Adaptation Strategy (SAS) that adaptively aligns the structures of unseen attributes and objects with those of trained seen attributes and objects with similar semantics. Notably, SPA is a plug-and-play method that can be seamlessly integrated into existing CZSL prompt tuning methods. Extensive experiments on OV-CZSL benchmarks demonstrate that SPA achieves competitive closed-set performance while significantly improving open-vocabulary results.

A data- and compute-efficient chest X-ray foundation model beyond aggressive scaling

Foundation models for medical imaging are typically pretrained on increasingly large datasets, following a "scale-at-all-costs" paradigm. However, this strategy faces two critical challenges: large-scale medical datasets often contain substantial redundancy and severe class imbalance that bias representation learning toward over-represented patterns, and indiscriminate training regardless of heterogeneity in data quality incurs considerable computational inefficiency. Here we demonstrate that active, principled data curation during pretraining can serve as a viable, cost-effective alternative to brute-force dataset enlargement. We introduce CheXficient, a chest X-ray (CXR) foundation model that selectively prioritizes informative training samples. CheXficient is pretrained on only 22.7% of 1,235,004 paired CXR images and reports while consuming under 27.3% of the total compute budget, yet achieving comparable or superior performance to its full-data counterpart and other large-scale pretrained models. We assess CheXficient across 20 individual benchmarks spanning 5 task types, including non-adapted off-the-shelf evaluations (zero-shot findings classification and crossmodal retrieval) and adapted downstream tasks (disease prediction, semantic segmentation, and radiology report generation). Further analyses show that CheXficient systematically prioritizes under-represented training samples, improving generalizability on long-tailed or rare conditions. Overall, our work offers practical insights into the data and computation demands for efficient pretraining and downstream adaptation of medical vision-language foundation models.

Parallel Track Transformers: Enabling Fast GPU Inference with Reduced Synchronization

Efficient large-scale inference of transformer-based large language models (LLMs) remains a fundamental systems challenge, frequently requiring multi-GPU parallelism to meet stringent latency and throughput targets. Conventional tensor parallelism decomposes matrix operations across devices but introduces substantial inter-GPU synchronization, leading to communication bottlenecks and degraded scalability. We propose the Parallel Track (PT) Transformer, a novel architectural paradigm that restructures computation to minimize cross-device dependencies. PT achieves up to a 16x reduction in synchronization operations relative to standard tensor parallelism, while maintaining competitive model quality in our experiments. We integrate PT into two widely adopted LLM serving stacks-Tensor-RT-LLM and vLLM-and report consistent improvements in serving efficiency, including up to 15-30% reduced time to first token, 2-12% reduced time per output token, and up to 31.90% increased throughput in both settings.

Fire on Motion: Optimizing Video Pass-bands for Efficient Spiking Action Recognition

Spiking neural networks (SNNs) have gained traction in vision due to their energy efficiency, bio-plausibility, and inherent temporal processing. Yet, despite this temporal capacity, most progress concentrates on static image benchmarks, and SNNs still underperform on dynamic video tasks compared to artificial neural networks (ANNs). In this work, we diagnose a fundamental pass-band mismatch: Standard spiking dynamics behave as a temporal low pass that emphasizes static content while attenuating motion bearing bands, where task relevant information concentrates in dynamic tasks. This phenomenon explains why SNNs can approach ANNs on static tasks yet fall behind on tasks that demand richer temporal understanding.To remedy this, we propose the Pass-Bands Optimizer (PBO), a plug-and-play module that optimizes the temporal pass-band toward task-relevant motion bands. PBO introduces only two learnable parameters, and a lightweight consistency constraint that preserves semantics and boundaries, incurring negligible computational overhead and requires no architectural changes. PBO deliberately suppresses static components that contribute little to discrimination, effectively high passing the stream so that spiking activity concentrates on motion bearing content. On UCF101, PBO yields over ten percentage points improvement. On more complex multi-modal action recognition and weakly supervised video anomaly detection, PBO delivers consistent and significant gains, offering a new perspective for SNN based video processing and understanding.

SPLA: Block Sparse Plus Linear Attention for Long Context Modeling

Block-wise sparse attention offers significant efficiency gains for long-context modeling, yet existing methods often suffer from low selection fidelity and cumulative contextual loss by completely discarding unselected blocks. To address these limitations, we introduce Sparse Plus Linear Attention (SPLA), a framework that utilizes a selection metric derived from second-order Taylor expansions to accurately identify relevant blocks for exact attention. Instead of discarding the remaining "long tail," SPLA compresses unselected blocks into a compact recurrent state via a residual linear attention (RLA) module. Crucially, to avoid IO overhead, we derive an optimized subtraction-based formulation for RLA -- calculating the residual as the difference between global and selected linear attention -- ensuring that unselected blocks are never explicitly accessed during inference. Our experiments demonstrate that SPLA closes the performance gap in continual pretraining, surpassing dense attention models on long-context benchmarks like RULER while maintaining competitive general knowledge and reasoning capabilities.

Evaluation of Large Language Models in Legal Applications: Challenges, Methods, and Future Directions

Large language models (LLMs) are being increasingly integrated into legal applications, including judicial decision support, legal practice assistance, and public-facing legal services. While LLMs show strong potential in handling legal knowledge and tasks, their deployment in real-world legal settings raises critical concerns beyond surface-level accuracy, involving the soundness of legal reasoning processes and trustworthy issues such as fairness and reliability. Systematic evaluation of LLM performance in legal tasks has therefore become essential for their responsible adoption. This survey identifies key challenges in evaluating LLMs for legal tasks grounded in real-world legal practice. We analyze the major difficulties involved in assessing LLM performance in the legal domain, including outcome correctness, reasoning reliability, and trustworthiness. Building on these challenges, we review and categorize existing evaluation methods and benchmarks according to their task design, datasets, and evaluation metrics. We further discuss the extent to which current approaches address these challenges, highlight their limitations, and outline future research directions toward more realistic, reliable, and legally grounded evaluation frameworks for LLMs in legal domains.

Improving Flexible Image Tokenizers for Autoregressive Image Generation

Flexible image tokenizers aim to represent an image using an ordered 1D variable-length token sequence. This flexible tokenization is typically achieved through nested dropout, where a portion of trailing tokens is randomly truncated during training, and the image is reconstructed using the remaining preceding sequence. However, this tail-truncation strategy inherently concentrates the image information in the early tokens, limiting the effectiveness of downstream AutoRegressive (AR) image generation as the token length increases. To overcome these limitations, we propose \textbf{ReToK}, a flexible tokenizer with \underline{Re}dundant \underline{Tok}en Padding and Hierarchical Semantic Regularization, designed to fully exploit all tokens for enhanced latent modeling. Specifically, we introduce \textbf{Redundant Token Padding} to activate tail tokens more frequently, thereby alleviating information over-concentration in the early tokens. In addition, we apply \textbf{Hierarchical Semantic Regularization} to align the decoding features of earlier tokens with those from a pre-trained vision foundation model, while progressively reducing the regularization strength toward the tail to allow finer low-level detail reconstruction. Extensive experiments demonstrate the effectiveness of ReTok: on ImageNet 256$\times$256, our method achieves superior generation performance compared with both flexible and fixed-length tokenizers. Code will be available at: \href{https://github.com/zfu006/ReTok}{https://github.com/zfu006/ReTok}

Casting a SPELL: Sentence Pairing Exploration for LLM Limitation-breaking

Large language models (LLMs) have revolutionized software development through AI-assisted coding tools, enabling developers with limited programming expertise to create sophisticated applications. However, this accessibility extends to malicious actors who may exploit these powerful tools to generate harmful software. Existing jailbreaking research primarily focuses on general attack scenarios against LLMs, with limited exploration of malicious code generation as a jailbreak target. To address this gap, we propose SPELL, a comprehensive testing framework specifically designed to evaluate the weakness of security alignment in malicious code generation. Our framework employs a time-division selection strategy that systematically constructs jailbreaking prompts by intelligently combining sentences from a prior knowledge dataset, balancing exploration of novel attack patterns with exploitation of successful techniques. Extensive evaluation across three advanced code models (GPT-4.1, Claude-3.5, and Qwen2.5-Coder) demonstrates SPELL's effectiveness, achieving attack success rates of 83.75%, 19.38%, and 68.12% respectively across eight malicious code categories. The generated prompts successfully produce malicious code in real-world AI development tools such as Cursor, with outputs confirmed as malicious by state-of-the-art detection systems at rates exceeding 73%. These findings reveal significant security gaps in current LLM implementations and provide valuable insights for improving AI safety alignment in code generation applications.

Breaking the Modality Wall: Time-step Mixup for Efficient Spiking Knowledge Transfer from Static to Event Domain

The integration of event cameras and spiking neural networks (SNNs) promises energy-efficient visual intelligence, yet scarce event data and the sparsity of DVS outputs hinder effective training. Prior knowledge transfers from RGB to DVS often underperform because the distribution gap between modalities is substantial. In this work, we present Time-step Mixup Knowledge Transfer (TMKT), a cross-modal training framework with a probabilistic Time-step Mixup (TSM) strategy. TSM exploits the asynchronous nature of SNNs by interpolating RGB and DVS inputs at various time steps to produce a smooth curriculum within each sequence, which reduces gradient variance and stabilizes optimization with theoretical analysis. To employ auxiliary supervision from TSM, TMKT introduces two lightweight modality-aware objectives, Modality Aware Guidance (MAG) for per-frame source supervision and Mixup Ratio Perception (MRP) for sequence-level mix ratio estimation, which explicitly align temporal features with the mixing schedule. TMKT enables smoother knowledge transfer, helps mitigate modality mismatch during training, and achieves superior performance in spiking image classification tasks. Extensive experiments across diverse benchmarks and multiple SNN backbones, together with ablations, demonstrate the effectiveness of our method.