Indescribable Multi-modal Spatial Evaluator

Multi-modal image registration spatially aligns two images with different distributions. One of its major challenges is that images acquired from different imaging machines have different imaging distributions, making it difficult to focus only on the spatial aspect of the images and ignore differences in distributions. In this study, we developed a self-supervised approach, Indescribable Multi-model Spatial Evaluator (IMSE), to address multi-modal image registration. IMSE creates an accurate multi-modal spatial evaluator to measure spatial differences between two images, and then optimizes registration by minimizing the error predicted of the evaluator. To optimize IMSE performance, we also proposed a new style enhancement method called Shuffle Remap which randomizes the image distribution into multiple segments, and then randomly disorders and remaps these segments, so that the distribution of the original image is changed. Shuffle Remap can help IMSE to predict the difference in spatial location from unseen target distributions. Our results show that IMSE outperformed the existing methods for registration using T1-T2 and CT-MRI datasets. IMSE also can be easily integrated into the traditional registration process, and can provide a convenient way to evaluate and visualize registration results. IMSE also has the potential to be used as a new paradigm for image-to-image translation. Our code is available at https://github.com/Kid-Liet/IMSE.

Projection image-to-image translation in hybrid X-ray/MR imaging

The potential benefit of hybrid X-ray and MR imaging in the interventional environment is enormous. However, a vast amount of existing image enhancement methods requires the image information to be present in the same domain. To unlock this potential, we present a solution to image-to-image translation from MR projections to corresponding X-ray projection images. The approach is based on a state-of-the-art image generator network that is modified to fit the specific application. Furthermore, we propose the inclusion of a gradient map to the perceptual loss to emphasize high frequency details. The proposed approach is capable of creating X-ray projection images with natural appearance. Additionally, our extensions show clear improvement compared to the baseline method.

Multi-Modality Image Inpainting using Generative Adversarial Networks

Deep learning techniques, especially Generative Adversarial Networks (GANs) have significantly improved image inpainting and image-to-image translation tasks over the past few years. To the best of our knowledge, the problem of combining the image inpainting task with the multi-modality image-to-image translation remains intact. In this paper, we propose a model to address this problem. The model will be evaluated on combined night-to-day image translation and inpainting, along with promising qualitative and quantitative results.

DiffFaceSketch: High-Fidelity Face Image Synthesis with Sketch-Guided Latent Diffusion Model

Synthesizing face images from monochrome sketches is one of the most fundamental tasks in the field of image-to-image translation. However, it is still challenging to (1)~make models learn the high-dimensional face features such as geometry and color, and (2)~take into account the characteristics of input sketches. Existing methods often use sketches as indirect inputs (or as auxiliary inputs) to guide the models, resulting in the loss of sketch features or the alteration of geometry information. In this paper, we introduce a Sketch-Guided Latent Diffusion Model (SGLDM), an LDM-based network architect trained on the paired sketch-face dataset. We apply a Multi-Auto-Encoder (AE) to encode the different input sketches from different regions of a face from pixel space to a feature map in latent space, which enables us to reduce the dimension of the sketch input while preserving the geometry-related information of local face details. We build a sketch-face paired dataset based on the existing method that extracts the edge map from an image. We then introduce a Stochastic Region Abstraction (SRA), an approach to augment our dataset to improve the robustness of SGLDM to handle sketch input with arbitrary abstraction. The evaluation study shows that SGLDM can synthesize high-quality face images with different expressions, facial accessories, and hairstyles from various sketches with different abstraction levels.

Artifact Removal in Histopathology Images

In the clinical setting of histopathology, whole-slide image (WSI) artifacts frequently arise, distorting regions of interest, and having a pernicious impact on WSI analysis. Image-to-image translation networks such as CycleGANs are in principle capable of learning an artifact removal function from unpaired data. However, we identify a surjection problem with artifact removal, and propose an weakly-supervised extension to CycleGAN to address this. We assemble a pan-cancer dataset comprising artifact and clean tiles from the TCGA database. Promising results highlight the soundness of our method.

Domain Bridge for Unpaired Image-to-Image Translation and Unsupervised Domain Adaptation

Image-to-image translation architectures may have limited effectiveness in some circumstances. For example, while generating rainy scenarios, they may fail to model typical traits of rain as water drops, and this ultimately impacts the synthetic images realism. With our method, called domain bridge, web-crawled data are exploited to reduce the domain gap, leading to the inclusion of previously ignored elements in the generated images. We make use of a network for clear to rain translation trained with the domain bridge to extend our work to Unsupervised Domain Adaptation (UDA). In that context, we introduce an online multimodal style-sampling strategy, where image translation multimodality is exploited at training time to improve performances. Finally, a novel approach for self-supervised learning is presented, and used to further align the domains. With our contributions, we simultaneously increase the realism of the generated images, while reaching on par performances w.r.t. the UDA state-of-the-art, with a simpler approach.

Unsupervised Cardiac Segmentation Utilizing Synthesized Images from Anatomical Labels

Cardiac segmentation is in great demand for clinical practice. Due to the enormous labor of manual delineation, unsupervised segmentation is desired. The ill-posed optimization problem of this task is inherently challenging, requiring well-designed constraints. In this work, we propose an unsupervised framework for multi-class segmentation with both intensity and shape constraints. Firstly, we extend a conventional non-convex energy function as an intensity constraint and implement it with U-Net. For shape constraint, synthetic images are generated from anatomical labels via image-to-image translation, as shape supervision for the segmentation network. Moreover, augmentation invariance is applied to facilitate the segmentation network to learn the latent features in terms of shape. We evaluated the proposed framework using the public datasets from MICCAI2019 MSCMR Challenge and achieved promising results on cardiac MRIs with Dice scores of 0.5737, 0.7796, and 0.6287 in Myo, LV, and RV, respectively.

Unsupervised Image-to-Image Translation with Generative Adversarial Networks

It's useful to automatically transform an image from its original form to some synthetic form (style, partial contents, etc.), while keeping the original structure or semantics. We define this requirement as the "image-to-image translation" problem, and propose a general approach to achieve it, based on deep convolutional and conditional generative adversarial networks (GANs), which has gained a phenomenal success to learn mapping images from noise input since 2014. In this work, we develop a two step (unsupervised) learning method to translate images between different domains by using unlabeled images without specifying any correspondence between them, so that to avoid the cost of acquiring labeled data. Compared with prior works, we demonstrated the capacity of generality in our model, by which variance of translations can be conduct by a single type of model. Such capability is desirable in applications like bidirectional translation

Describe What to Change: A Text-guided Unsupervised Image-to-Image Translation Approach

Manipulating visual attributes of images through human-written text is a very challenging task. On the one hand, models have to learn the manipulation without the ground truth of the desired output. On the other hand, models have to deal with the inherent ambiguity of natural language. Previous research usually requires either the user to describe all the characteristics of the desired image or to use richly-annotated image captioning datasets. In this work, we propose a novel unsupervised approach, based on image-to-image translation, that alters the attributes of a given image through a command-like sentence such as "change the hair color to black". Contrarily to state-of-the-art approaches, our model does not require a human-annotated dataset nor a textual description of all the attributes of the desired image, but only those that have to be modified. Our proposed model disentangles the image content from the visual attributes, and it learns to modify the latter using the textual description, before generating a new image from the content and the modified attribute representation. Because text might be inherently ambiguous (blond hair may refer to different shadows of blond, e.g. golden, icy, sandy), our method generates multiple stochastic versions of the same translation. Experiments show that the proposed model achieves promising performances on two large-scale public datasets: CelebA and CUB. We believe our approach will pave the way to new avenues of research combining textual and speech commands with visual attributes.