Node importance estimation (NIE) in heterogeneous knowledge graphs is a critical yet challenging task, essential for applications such as recommendation, knowledge reasoning, and question answering. Existing methods often rely on pairwise connections, neglecting high-order dependencies among multiple entities and relations, and they treat structural and semantic signals independently, hindering effective cross-modal integration. To address these challenges, we propose MetaHGNIE, a meta-path induced hypergraph contrastive learning framework for disentangling and aligning structural and semantic information. MetaHGNIE constructs a higher-order knowledge graph via meta-path sequences, where typed hyperedges capture multi-entity relational contexts. Structural dependencies are aggregated with local attention, while semantic representations are encoded through a hypergraph transformer equipped with sparse chunking to reduce redundancy. Finally, a multimodal fusion module integrates structural and semantic embeddings under contrastive learning with auxiliary supervision, ensuring robust cross-modal alignment. Extensive experiments on benchmark NIE datasets demonstrate that MetaHGNIE consistently outperforms state-of-the-art baselines. These results highlight the effectiveness of explicitly modeling higher-order interactions and cross-modal alignment in heterogeneous knowledge graphs. Our code is available at https://github.com/SEU-WENJIA/DualHNIE




Depression represents a global mental health challenge requiring efficient and reliable automated detection methods. Current Transformer- or Graph Neural Networks (GNNs)-based multimodal depression detection methods face significant challenges in modeling individual differences and cross-modal temporal dependencies across diverse behavioral contexts. Therefore, we propose P$^3$HF (Personality-guided Public-Private Domain Disentangled Hypergraph-Former Network) with three key innovations: (1) personality-guided representation learning using LLMs to transform discrete individual features into contextual descriptions for personalized encoding; (2) Hypergraph-Former architecture modeling high-order cross-modal temporal relationships; (3) event-level domain disentanglement with contrastive learning for improved generalization across behavioral contexts. Experiments on MPDD-Young dataset show P$^3$HF achieves around 10\% improvement on accuracy and weighted F1 for binary and ternary depression classification task over existing methods. Extensive ablation studies validate the independent contribution of each architectural component, confirming that personality-guided representation learning and high-order hypergraph reasoning are both essential for generating robust, individual-aware depression-related representations. The code is released at https://github.com/hacilab/P3HF.




Road network representation learning (RNRL) has attracted increasing attention from both researchers and practitioners as various spatiotemporal tasks are emerging. Recent advanced methods leverage Graph Neural Networks (GNNs) and contrastive learning to characterize the spatial structure of road segments in a self-supervised paradigm. However, spatial heterogeneity and temporal dynamics of road networks raise severe challenges to the neighborhood smoothing mechanism of self-supervised GNNs. To address these issues, we propose a $\textbf{D}$ual-branch $\textbf{S}$patial-$\textbf{T}$emporal self-supervised representation framework for enhanced road representations, termed as DST. On one hand, DST designs a mix-hop transition matrix for graph convolution to incorporate dynamic relations of roads from trajectories. Besides, DST contrasts road representations of the vanilla road network against that of the hypergraph in a spatial self-supervised way. The hypergraph is newly built based on three types of hyperedges to capture long-range relations. On the other hand, DST performs next token prediction as the temporal self-supervised task on the sequences of traffic dynamics based on a causal Transformer, which is further regularized by differentiating traffic modes of weekdays from those of weekends. Extensive experiments against state-of-the-art methods verify the superiority of our proposed framework. Moreover, the comprehensive spatiotemporal modeling facilitates DST to excel in zero-shot learning scenarios.
The burgeoning presence of multimodal content-sharing platforms propels the development of personalized recommender systems. Previous works usually suffer from data sparsity and cold-start problems, and may fail to adequately explore semantic user-product associations from multimodal data. To address these issues, we propose a novel Multi-Modal Hypergraph Contrastive Learning (MMHCL) framework for user recommendation. For a comprehensive information exploration from user-product relations, we construct two hypergraphs, i.e. a user-to-user (u2u) hypergraph and an item-to-item (i2i) hypergraph, to mine shared preferences among users and intricate multimodal semantic resemblance among items, respectively. This process yields denser second-order semantics that are fused with first-order user-item interaction as complementary to alleviate the data sparsity issue. Then, we design a contrastive feature enhancement paradigm by applying synergistic contrastive learning. By maximizing/minimizing the mutual information between second-order (e.g. shared preference pattern for users) and first-order (information of selected items for users) embeddings of the same/different users and items, the feature distinguishability can be effectively enhanced. Compared with using sparse primary user-item interaction only, our MMHCL obtains denser second-order hypergraphs and excavates more abundant shared attributes to explore the user-product associations, which to a certain extent alleviates the problems of data sparsity and cold-start. Extensive experiments have comprehensively demonstrated the effectiveness of our method. Our code is publicly available at: https://github.com/Xu107/MMHCL.
Real-world networks usually have a property of node heterophily, that is, the connected nodes usually have different features or different labels. This heterophily issue has been extensively studied in homogeneous graphs but remains under-explored in heterogeneous graphs, where there are multiple types of nodes and edges. Capturing node heterophily in heterogeneous graphs is very challenging since both node/edge heterogeneity and node heterophily should be carefully taken into consideration. Existing methods typically convert heterogeneous graphs into homogeneous ones to learn node heterophily, which will inevitably lose the potential heterophily conveyed by heterogeneous relations. To bridge this gap, we propose Relation-Aware Separation of Homophily and Heterophily (RASH), a novel contrastive learning framework that explicitly models high-order semantics of heterogeneous interactions and adaptively separates homophilic and heterophilic patterns. Particularly, RASH introduces dual heterogeneous hypergraphs to encode multi-relational bipartite subgraphs and dynamically constructs homophilic graphs and heterophilic graphs based on relation importance. A multi-relation contrastive loss is designed to align heterogeneous and homophilic/heterophilic views by maximizing mutual information. In this way, RASH simultaneously resolves the challenges of heterogeneity and heterophily in heterogeneous graphs. Extensive experiments on benchmark datasets demonstrate the effectiveness of RASH across various downstream tasks. The code is available at: https://github.com/zhengziyu77/RASH.
Real-world knowledge can take various forms, including structured, semi-structured, and unstructured data. Among these, knowledge graphs are a form of structured human knowledge that integrate heterogeneous data sources into structured representations but typically reduce complex n-ary relations to simple triples, thereby losing higher-order relational details. In contrast, hypergraphs naturally represent n-ary relations with hyperedges, which directly connect multiple entities together. Yet hypergraph representation learning often overlooks entity roles in hyperedges, limiting the fine-grained semantic modelling. To address these issues, knowledge hypergraphs and hyper-relational knowledge graphs combine the advantages of knowledge graphs and hypergraphs to better capture the complex structures and role-specific semantics of real-world knowledge. This survey provides a comprehensive review of methods handling n-ary relational data, covering both knowledge hypergraphs and hyper-relational knowledge graphs literatures. We propose a two-dimensional taxonomy: the first dimension categorises models based on their methodology, i.e., translation-based models, tensor factorisation-based models, deep neural network-based models, logic rules-based models, and hyperedge expansion-based models. The second dimension classifies models according to their awareness of entity roles and positions in n-ary relations, dividing them into aware-less, position-aware, and role-aware approaches. Finally, we discuss existing datasets, negative sampling strategies, and outline open challenges to inspire future research.




Virtual stain transfer leverages computer-assisted technology to transform the histochemical staining patterns of tissue samples into other staining types. However, existing methods often lose detailed pathological information due to the limitations of the cycle consistency assumption. To address this challenge, we propose STNHCL, a hypergraph-based patch-wise contrastive learning method. STNHCL captures higher-order relationships among patches through hypergraph modeling, ensuring consistent higher-order topology between input and output images. Additionally, we introduce a novel negative sample weighting strategy that leverages discriminator heatmaps to apply different weights based on the Gaussian distribution for tissue and background, thereby enhancing traditional weighting methods. Experiments demonstrate that STNHCL achieves state-of-the-art performance in the two main categories of stain transfer tasks. Furthermore, our model also performs excellently in downstream tasks. Code will be made available.




The burgeoning presence of Large Language Models (LLM) is propelling the development of personalized recommender systems. Most existing LLM-based methods fail to sufficiently explore the multi-view graph structure correlations inherent in recommendation scenarios. To this end, we propose a novel framework, Hypergraph Enhanced LLM Learning for multimodal Recommendation (HeLLM), designed to equip LLMs with the capability to capture intricate higher-order semantic correlations by fusing graph-level contextual signals with sequence-level behavioral patterns. In the recommender pre-training phase, we design a user hypergraph to uncover shared interest preferences among users and an item hypergraph to capture correlations within multimodal similarities among items. The hypergraph convolution and synergistic contrastive learning mechanism are introduced to enhance the distinguishability of learned representations. In the LLM fine-tuning phase, we inject the learned graph-structured embeddings directly into the LLM's architecture and integrate sequential features capturing each user's chronological behavior. This process enables hypergraphs to leverage graph-structured information as global context, enhancing the LLM's ability to perceive complex relational patterns and integrate multimodal information, while also modeling local temporal dynamics. Extensive experiments demonstrate the superiority of our proposed method over state-of-the-art baselines, confirming the advantages of fusing hypergraph-based context with sequential user behavior in LLMs for recommendation.
Existing methods for multimodal MRI segmentation with missing modalities typically assume that all MRI modalities are available during training. However, in clinical practice, some modalities may be missing due to the sequential nature of MRI acquisition, leading to performance degradation. Furthermore, retraining models to accommodate newly available modalities can be inefficient and may cause overfitting, potentially compromising previously learned knowledge. To address these challenges, we propose Replay-based Hypergraph Domain Incremental Learning (ReHyDIL) for brain tumor segmentation with missing modalities. ReHyDIL leverages Domain Incremental Learning (DIL) to enable the segmentation model to learn from newly acquired MRI modalities without forgetting previously learned information. To enhance segmentation performance across diverse patient scenarios, we introduce the Cross-Patient Hypergraph Segmentation Network (CHSNet), which utilizes hypergraphs to capture high-order associations between patients. Additionally, we incorporate Tversky-Aware Contrastive (TAC) loss to effectively mitigate information imbalance both across and within different modalities. Extensive experiments on the BraTS2019 dataset demonstrate that ReHyDIL outperforms state-of-the-art methods, achieving an improvement of over 2\% in the Dice Similarity Coefficient across various tumor regions. Our code is available at ReHyDIL.
Hypergraphs provide a superior modeling framework for representing complex multidimensional relationships in the context of real-world interactions that often occur in groups, overcoming the limitations of traditional homogeneous graphs. However, there have been few studies on hypergraphbased contrastive learning, and existing graph-based contrastive learning methods have not been able to fully exploit the highorder correlation information in hypergraphs. Here, we propose a Hypergraph Fine-grained contrastive learning (HyFi) method designed to exploit the complex high-dimensional information inherent in hypergraphs. While avoiding traditional graph augmentation methods that corrupt the hypergraph topology, the proposed method provides a simple and efficient learning augmentation function by adding noise to node features. Furthermore, we expands beyond the traditional dichotomous relationship between positive and negative samples in contrastive learning by introducing a new relationship of weak positives. It demonstrates the importance of fine-graining positive samples in contrastive learning. Therefore, HyFi is able to produce highquality embeddings, and outperforms both supervised and unsupervised baselines in average rank on node classification across 10 datasets. Our approach effectively exploits high-dimensional hypergraph information, shows significant improvement over existing graph-based contrastive learning methods, and is efficient in terms of training speed and GPU memory cost. The source code is available at https://github.com/Noverse0/HyFi.git.