Exploiting Layer Normalization Fine-tuning in Visual Transformer Foundation Models for Classification

LayerNorm is pivotal in Vision Transformers (ViTs), yet its fine-tuning dynamics under data scarcity and domain shifts remain underexplored. This paper shows that shifts in LayerNorm parameters after fine-tuning (LayerNorm shifts) are indicative of the transitions between source and target domains; its efficacy is contingent upon the degree to which the target training samples accurately represent the target domain, as quantified by our proposed Fine-tuning Shift Ratio ($FSR$). Building on this, we propose a simple yet effective rescaling mechanism using a scalar $\lambda$ that is negatively correlated to $FSR$ to align learned LayerNorm shifts with those ideal shifts achieved under fully representative data, combined with a cyclic framework that further enhances the LayerNorm fine-tuning. Extensive experiments across natural and pathological images, in both in-distribution (ID) and out-of-distribution (OOD) settings, and various target training sample regimes validate our framework. Notably, OOD tasks tend to yield lower $FSR$ and higher $\lambda$ in comparison to ID cases, especially with scarce data, indicating under-represented target training samples. Moreover, ViTFs fine-tuned on pathological data behave more like ID settings, favoring conservative LayerNorm updates. Our findings illuminate the underexplored dynamics of LayerNorm in transfer learning and provide practical strategies for LayerNorm fine-tuning.

Enhancing Spatial Reasoning through Visual and Textual Thinking

The spatial reasoning task aims to reason about the spatial relationships in 2D and 3D space, which is a fundamental capability for Visual Question Answering (VQA) and robotics. Although vision language models (VLMs) have developed rapidly in recent years, they are still struggling with the spatial reasoning task. In this paper, we introduce a method that can enhance Spatial reasoning through Visual and Textual thinking Simultaneously (SpatialVTS). In the spatial visual thinking phase, our model is trained to generate location-related specific tokens of essential targets automatically. Not only are the objects mentioned in the problem addressed, but also the potential objects related to the reasoning are considered. During the spatial textual thinking phase, Our model conducts long-term thinking based on visual cues and dialogues, gradually inferring the answers to spatial reasoning problems. To effectively support the model's training, we perform manual corrections to the existing spatial reasoning dataset, eliminating numerous incorrect labels resulting from automatic annotation, restructuring the data input format to enhance generalization ability, and developing thinking processes with logical reasoning details. Without introducing additional information (such as masks or depth), our model's overall average level in several spatial understanding tasks has significantly improved compared with other models.

FinGAIA: An End-to-End Benchmark for Evaluating AI Agents in Finance

The booming development of AI agents presents unprecedented opportunities for automating complex tasks across various domains. However, their multi-step, multi-tool collaboration capabilities in the financial sector remain underexplored. This paper introduces FinGAIA, an end-to-end benchmark designed to evaluate the practical abilities of AI agents in the financial domain. FinGAIA comprises 407 meticulously crafted tasks, spanning seven major financial sub-domains: securities, funds, banking, insurance, futures, trusts, and asset management. These tasks are organized into three hierarchical levels of scenario depth: basic business analysis, asset decision support, and strategic risk management. We evaluated 10 mainstream AI agents in a zero-shot setting. The best-performing agent, ChatGPT, achieved an overall accuracy of 48.9\%, which, while superior to non-professionals, still lags financial experts by over 35 percentage points. Error analysis has revealed five recurring failure patterns: Cross-modal Alignment Deficiency, Financial Terminological Bias, Operational Process Awareness Barrier, among others. These patterns point to crucial directions for future research. Our work provides the first agent benchmark closely related to the financial domain, aiming to objectively assess and promote the development of agents in this crucial field. Partial data is available at https://github.com/SUFE-AIFLM-Lab/FinGAIA.

PAST: A multimodal single-cell foundation model for histopathology and spatial transcriptomics in cancer

While pathology foundation models have transformed cancer image analysis, they often lack integration with molecular data at single-cell resolution, limiting their utility for precision oncology. Here, we present PAST, a pan-cancer single-cell foundation model trained on 20 million paired histopathology images and single-cell transcriptomes spanning multiple tumor types and tissue contexts. By jointly encoding cellular morphology and gene expression, PAST learns unified cross-modal representations that capture both spatial and molecular heterogeneity at the cellular level. This approach enables accurate prediction of single-cell gene expression, virtual molecular staining, and multimodal survival analysis directly from routine pathology slides. Across diverse cancers and downstream tasks, PAST consistently exceeds the performance of existing approaches, demonstrating robust generalizability and scalability. Our work establishes a new paradigm for pathology foundation models, providing a versatile tool for high-resolution spatial omics, mechanistic discovery, and precision cancer research.

Structure-aware Semantic Discrepancy and Consistency for 3D Medical Image Self-supervised Learning

3D medical image self-supervised learning (mSSL) holds great promise for medical analysis. Effectively supporting broader applications requires considering anatomical structure variations in location, scale, and morphology, which are crucial for capturing meaningful distinctions. However, previous mSSL methods partition images with fixed-size patches, often ignoring the structure variations. In this work, we introduce a novel perspective on 3D medical images with the goal of learning structure-aware representations. We assume that patches within the same structure share the same semantics (semantic consistency) while those from different structures exhibit distinct semantics (semantic discrepancy). Based on this assumption, we propose an mSSL framework named $S^2DC$, achieving Structure-aware Semantic Discrepancy and Consistency in two steps. First, $S^2DC$ enforces distinct representations for different patches to increase semantic discrepancy by leveraging an optimal transport strategy. Second, $S^2DC$ advances semantic consistency at the structural level based on neighborhood similarity distribution. By bridging patch-level and structure-level representations, $S^2DC$ achieves structure-aware representations. Thoroughly evaluated across 10 datasets, 4 tasks, and 3 modalities, our proposed method consistently outperforms the state-of-the-art methods in mSSL.

A Gift from the Integration of Discriminative and Diffusion-based Generative Learning: Boundary Refinement Remote Sensing Semantic Segmentation

Remote sensing semantic segmentation must address both what the ground objects are within an image and where they are located. Consequently, segmentation models must ensure not only the semantic correctness of large-scale patches (low-frequency information) but also the precise localization of boundaries between patches (high-frequency information). However, most existing approaches rely heavily on discriminative learning, which excels at capturing low-frequency features, while overlooking its inherent limitations in learning high-frequency features for semantic segmentation. Recent studies have revealed that diffusion generative models excel at generating high-frequency details. Our theoretical analysis confirms that the diffusion denoising process significantly enhances the model's ability to learn high-frequency features; however, we also observe that these models exhibit insufficient semantic inference for low-frequency features when guided solely by the original image. Therefore, we integrate the strengths of both discriminative and generative learning, proposing the Integration of Discriminative and diffusion-based Generative learning for Boundary Refinement (IDGBR) framework. The framework first generates a coarse segmentation map using a discriminative backbone model. This map and the original image are fed into a conditioning guidance network to jointly learn a guidance representation subsequently leveraged by an iterative denoising diffusion process refining the coarse segmentation. Extensive experiments across five remote sensing semantic segmentation datasets (binary and multi-class segmentation) confirm our framework's capability of consistent boundary refinement for coarse results from diverse discriminative architectures. The source code will be available at https://github.com/KeyanHu-git/IDGBR.

SFNet: Fusion of Spatial and Frequency-Domain Features for Remote Sensing Image Forgery Detection

The rapid advancement of generative artificial intelligence is producing fake remote sensing imagery (RSI) that is increasingly difficult to detect, potentially leading to erroneous intelligence, fake news, and even conspiracy theories. Existing forgery detection methods typically rely on single visual features to capture predefined artifacts, such as spatial-domain cues to detect forged objects like roads or buildings in RSI, or frequency-domain features to identify artifacts from up-sampling operations in adversarial generative networks (GANs). However, the nature of artifacts can significantly differ depending on geographic terrain, land cover types, or specific features within the RSI. Moreover, these complex artifacts evolve as generative models become more sophisticated. In short, over-reliance on a single visual cue makes existing forgery detectors struggle to generalize across diverse remote sensing data. This paper proposed a novel forgery detection framework called SFNet, designed to identify fake images in diverse remote sensing data by leveraging spatial and frequency domain features. Specifically, to obtain rich and comprehensive visual information, SFNet employs two independent feature extractors to capture spatial and frequency domain features from input RSIs. To fully utilize the complementary domain features, the domain feature mapping module and the hybrid domain feature refinement module(CBAM attention) of SFNet are designed to successively align and fuse the multi-domain features while suppressing redundant information. Experiments on three datasets show that SFNet achieves an accuracy improvement of 4%-15.18% over the state-of-the-art RS forgery detection methods and exhibits robust generalization capabilities. The code is available at https://github.com/GeoX-Lab/RSTI/tree/main/SFNet.

Efficient Network Automatic Relevance Determination

We propose Network Automatic Relevance Determination (NARD), an extension of ARD for linearly probabilistic models, to simultaneously model sparse relationships between inputs $X \in \mathbb R^{d \times N}$ and outputs $Y \in \mathbb R^{m \times N}$, while capturing the correlation structure among the $Y$. NARD employs a matrix normal prior which contains a sparsity-inducing parameter to identify and discard irrelevant features, thereby promoting sparsity in the model. Algorithmically, it iteratively updates both the precision matrix and the relationship between $Y$ and the refined inputs. To mitigate the computational inefficiencies of the $\mathcal O(m^3 + d^3)$ cost per iteration, we introduce Sequential NARD, which evaluates features sequentially, and a Surrogate Function Method, leveraging an efficient approximation of the marginal likelihood and simplifying the calculation of determinant and inverse of an intermediate matrix. Combining the Sequential update with the Surrogate Function method further reduces computational costs. The computational complexity per iteration for these three methods is reduced to $\mathcal O(m^3+p^3)$, $\mathcal O(m^3 + d^2)$, $\mathcal O(m^3+p^2)$, respectively, where $p \ll d$ is the final number of features in the model. Our methods demonstrate significant improvements in computational efficiency with comparable performance on both synthetic and real-world datasets.

Fast on the Easy, Deep on the Hard: Efficient Reasoning via Powered Length Penalty

Large language models (LLMs) have demonstrated significant advancements in reasoning capabilities, performing well on various challenging benchmarks. Techniques like Chain-of-Thought prompting have been introduced to further improve reasoning. However, these approaches frequently generate longer outputs, which in turn increase computational latency. Although some methods use reinforcement learning to shorten reasoning, they often apply uniform penalties without considering the problem's complexity, leading to suboptimal outcomes. In this study, we seek to enhance the efficiency of LLM reasoning by promoting conciseness for simpler problems while preserving sufficient reasoning for more complex ones for accuracy, thus improving the model's overall performance. Specifically, we manage the model's reasoning efficiency by dividing the reward function and including a novel penalty for output length. Our approach has yielded impressive outcomes in benchmark evaluations across three datasets: GSM8K, MATH500, and AIME2024. For the comparatively simpler datasets GSM8K and MATH500, our method has effectively shortened output lengths while preserving or enhancing accuracy. On the more demanding AIME2024 dataset, our approach has resulted in improved accuracy.

ChromFound: Towards A Universal Foundation Model for Single-Cell Chromatin Accessibility Data

The advent of single-cell Assay for Transposase-Accessible Chromatin using sequencing (scATAC-seq) offers an innovative perspective for deciphering regulatory mechanisms by assembling a vast repository of single-cell chromatin accessibility data. While foundation models have achieved significant success in single-cell transcriptomics, there is currently no foundation model for scATAC-seq that supports zero-shot high-quality cell identification and comprehensive multi-omics analysis simultaneously. Key challenges lie in the high dimensionality and sparsity of scATAC-seq data, as well as the lack of a standardized schema for representing open chromatin regions (OCRs). Here, we present \textbf{ChromFound}, a foundation model tailored for scATAC-seq. ChromFound utilizes a hybrid architecture and genome-aware tokenization to effectively capture genome-wide long contexts and regulatory signals from dynamic chromatin landscapes. Pretrained on 1.97 million cells from 30 tissues and 6 disease conditions, ChromFound demonstrates broad applicability across 6 diverse tasks. Notably, it achieves robust zero-shot performance in generating universal cell representations and exhibits excellent transferability in cell type annotation and cross-omics prediction. By uncovering enhancer-gene links undetected by existing computational methods, ChromFound offers a promising framework for understanding disease risk variants in the noncoding genome.