3D-TransUNet for Brain Metastases Segmentation in the BraTS2023 Challenge

Segmenting brain tumors is complex due to their diverse appearances and scales. Brain metastases, the most common type of brain tumor, are a frequent complication of cancer. Therefore, an effective segmentation model for brain metastases must adeptly capture local intricacies to delineate small tumor regions while also integrating global context to understand broader scan features. The TransUNet model, which combines Transformer self-attention with U-Net's localized information, emerges as a promising solution for this task. In this report, we address brain metastases segmentation by training the 3D-TransUNet model on the Brain Tumor Segmentation (BraTS-METS) 2023 challenge dataset. Specifically, we explored two architectural configurations: the Encoder-only 3D-TransUNet, employing Transformers solely in the encoder, and the Decoder-only 3D-TransUNet, utilizing Transformers exclusively in the decoder. For Encoder-only 3D-TransUNet, we note that Masked-Autoencoder pre-training is required for a better initialization of the Transformer Encoder and thus accelerates the training process. We identify that the Decoder-only 3D-TransUNet model should offer enhanced efficacy in the segmentation of brain metastases, as indicated by our 5-fold cross-validation on the training set. However, our use of the Encoder-only 3D-TransUNet model already yield notable results, with an average lesion-wise Dice score of 59.8\% on the test set, securing second place in the BraTS-METS 2023 challenge.

Revisiting Adversarial Training at Scale

The machine learning community has witnessed a drastic change in the training pipeline, pivoted by those ''foundation models'' with unprecedented scales. However, the field of adversarial training is lagging behind, predominantly centered around small model sizes like ResNet-50, and tiny and low-resolution datasets like CIFAR-10. To bridge this transformation gap, this paper provides a modern re-examination with adversarial training, investigating its potential benefits when applied at scale. Additionally, we introduce an efficient and effective training strategy to enable adversarial training with giant models and web-scale data at an affordable computing cost. We denote this newly introduced framework as AdvXL. Empirical results demonstrate that AdvXL establishes new state-of-the-art robust accuracy records under AutoAttack on ImageNet-1K. For example, by training on DataComp-1B dataset, our AdvXL empowers a vanilla ViT-g model to substantially surpass the previous records of $l_{\infty}$-, $l_{2}$-, and $l_{1}$-robust accuracy by margins of 11.4%, 14.2% and 12.9%, respectively. This achievement posits AdvXL as a pioneering approach, charting a new trajectory for the efficient training of robust visual representations at significantly larger scales. Our code is available at https://github.com/UCSC-VLAA/AdvXL.

3D TransUNet: Advancing Medical Image Segmentation through Vision Transformers

Medical image segmentation plays a crucial role in advancing healthcare systems for disease diagnosis and treatment planning. The u-shaped architecture, popularly known as U-Net, has proven highly successful for various medical image segmentation tasks. However, U-Net's convolution-based operations inherently limit its ability to model long-range dependencies effectively. To address these limitations, researchers have turned to Transformers, renowned for their global self-attention mechanisms, as alternative architectures. One popular network is our previous TransUNet, which leverages Transformers' self-attention to complement U-Net's localized information with the global context. In this paper, we extend the 2D TransUNet architecture to a 3D network by building upon the state-of-the-art nnU-Net architecture, and fully exploring Transformers' potential in both the encoder and decoder design. We introduce two key components: 1) A Transformer encoder that tokenizes image patches from a convolution neural network (CNN) feature map, enabling the extraction of global contexts, and 2) A Transformer decoder that adaptively refines candidate regions by utilizing cross-attention between candidate proposals and U-Net features. Our investigations reveal that different medical tasks benefit from distinct architectural designs. The Transformer encoder excels in multi-organ segmentation, where the relationship among organs is crucial. On the other hand, the Transformer decoder proves more beneficial for dealing with small and challenging segmented targets such as tumor segmentation. Extensive experiments showcase the significant potential of integrating a Transformer-based encoder and decoder into the u-shaped medical image segmentation architecture. TransUNet outperforms competitors in various medical applications.

Consistency-guided Meta-Learning for Bootstrapping Semi-Supervised Medical Image Segmentation

Medical imaging has witnessed remarkable progress but usually requires a large amount of high-quality annotated data which is time-consuming and costly to obtain. To alleviate this burden, semi-supervised learning has garnered attention as a potential solution. In this paper, we present Meta-Learning for Bootstrapping Medical Image Segmentation (MLB-Seg), a novel method for tackling the challenge of semi-supervised medical image segmentation. Specifically, our approach first involves training a segmentation model on a small set of clean labeled images to generate initial labels for unlabeled data. To further optimize this bootstrapping process, we introduce a per-pixel weight mapping system that dynamically assigns weights to both the initialized labels and the model's own predictions. These weights are determined using a meta-process that prioritizes pixels with loss gradient directions closer to those of clean data, which is based on a small set of precisely annotated images. To facilitate the meta-learning process, we additionally introduce a consistency-based Pseudo Label Enhancement (PLE) scheme that improves the quality of the model's own predictions by ensembling predictions from various augmented versions of the same input. In order to improve the quality of the weight maps obtained through multiple augmentations of a single input, we introduce a mean teacher into the PLE scheme. This method helps to reduce noise in the weight maps and stabilize its generation process. Our extensive experimental results on public atrial and prostate segmentation datasets demonstrate that our proposed method achieves state-of-the-art results under semi-supervision. Our code is available at https://github.com/aijinrjinr/MLB-Seg.

CLIPA-v2: Scaling CLIP Training with 81.1% Zero-shot ImageNet Accuracy within a \$10,000 Budget; An Extra \$4,000 Unlocks 81.8% Accuracy

The recent work CLIPA presents an inverse scaling law for CLIP training -- whereby the larger the image/text encoders used, the shorter the sequence length of image/text tokens that can be applied in training. This finding enables us to train high-performance CLIP models with significantly reduced computations. Building upon this work, we hereby present CLIPA-v2 with two key contributions. Technically, we find this inverse scaling law is also applicable in the finetuning stage, enabling further reduction in computational needs. Empirically, we explore CLIPA at scale, extending the experiments up to the H/14 model with ~13B image-text pairs seen during training. Our results are exciting -- by only allocating a budget of \$10,000, our CLIP model achieves an impressive zero-shot ImageNet accuracy of 81.1%, surpassing the prior best CLIP model (from OpenCLIP, 80.1%) by 1.0% and meanwhile reducing the computational cost by ~39X. Moreover, with an additional investment of $4,000, we can further elevate the zero-shot ImageNet accuracy to 81.8%. Our code and models are available at https://github.com/UCSC-VLAA/CLIPA.

An Inverse Scaling Law for CLIP Training

CLIP, the first foundation model that connects images and text, has enabled many recent breakthroughs in computer vision. However, its associated training cost is prohibitively high, imposing a significant barrier to its widespread exploration. In this paper, we present a surprising finding that there exists an inverse scaling law for CLIP training, whereby the larger the image/text encoders used, the shorter the sequence length of image/text tokens that can be applied in training. Moreover, we showcase that the strategy for reducing image/text token length plays a crucial role in determining the quality of this scaling law. As a result of this finding, we are able to successfully train CLIP even by using academic resources. For example, on an A100 eight-GPU server, our CLIP models achieve zero-shot top-1 ImageNet accuracies of 63.2% in ~2 days, 67.8% in ~3 days, and 69.3% in ~4 days. By reducing the computation barrier associated with CLIP, we hope to inspire more research in this field, particularly from academics. Our code is available at https://github.com/UCSC-VLAA/CLIPA.

Unleashing the Power of Visual Prompting At the Pixel Level

This paper presents a simple and effective visual prompting method for adapting pre-trained models to downstream recognition tasks. Our method includes two key designs. First, rather than directly adding together the prompt and the image, we treat the prompt as an extra and independent learnable component. We show that the strategy of reconciling the prompt and the image matters, and find that warping the prompt around a properly shrinked image empirically works the best. Second, we re-introduce two "old tricks" commonly used in building transferable adversarial examples, i.e., input diversity and gradient normalization, into visual prompting. These techniques improve optimization and enable the prompt to generalize better. We provide extensive experimental results to demonstrate the effectiveness of our method. Using a CLIP model, our prompting method sets a new record of 82.8% average accuracy across 12 popular classification datasets, substantially surpassing the prior art by +5.6%. It is worth noting that this prompting performance already outperforms linear probing by +2.1% and can even match fully fine-tuning in certain datasets. In addition, our prompting method shows competitive performance across different data scales and against distribution shifts. The code is publicly available at https://github.com/UCSC-VLAA/EVP.

In Defense of Image Pre-Training for Spatiotemporal Recognition

Image pre-training, the current de-facto paradigm for a wide range of visual tasks, is generally less favored in the field of video recognition. By contrast, a common strategy is to directly train with spatiotemporal convolutional neural networks (CNNs) from scratch. Nonetheless, interestingly, by taking a closer look at these from-scratch learned CNNs, we note there exist certain 3D kernels that exhibit much stronger appearance modeling ability than others, arguably suggesting appearance information is already well disentangled in learning. Inspired by this observation, we hypothesize that the key to effectively leveraging image pre-training lies in the decomposition of learning spatial and temporal features, and revisiting image pre-training as the appearance prior to initializing 3D kernels. In addition, we propose Spatial-Temporal Separable (STS) convolution, which explicitly splits the feature channels into spatial and temporal groups, to further enable a more thorough decomposition of spatiotemporal features for fine-tuning 3D CNNs. Our experiments show that simply replacing 3D convolution with STS notably improves a wide range of 3D CNNs without increasing parameters and computation on both Kinetics-400 and Something-Something V2. Moreover, this new training pipeline consistently achieves better results on video recognition with significant speedup. For instance, we achieve +0.6% top-1 of Slowfast on Kinetics-400 over the strong 256-epoch 128-GPU baseline while fine-tuning for only 50 epochs with 4 GPUs. The code and models are available at https://github.com/UCSC-VLAA/Image-Pretraining-for-Video.

Fast AdvProp

Adversarial Propagation (AdvProp) is an effective way to improve recognition models, leveraging adversarial examples. Nonetheless, AdvProp suffers from the extremely slow training speed, mainly because: a) extra forward and backward passes are required for generating adversarial examples; b) both original samples and their adversarial counterparts are used for training (i.e., 2$\times$ data). In this paper, we introduce Fast AdvProp, which aggressively revamps AdvProp's costly training components, rendering the method nearly as cheap as the vanilla training. Specifically, our modifications in Fast AdvProp are guided by the hypothesis that disentangled learning with adversarial examples is the key for performance improvements, while other training recipes (e.g., paired clean and adversarial training samples, multi-step adversarial attackers) could be largely simplified. Our empirical results show that, compared to the vanilla training baseline, Fast AdvProp is able to further model performance on a spectrum of visual benchmarks, without incurring extra training cost. Additionally, our ablations find Fast AdvProp scales better if larger models are used, is compatible with existing data augmentation methods (i.e., Mixup and CutMix), and can be easily adapted to other recognition tasks like object detection. The code is available here: https://github.com/meijieru/fast_advprop.

Learning to Bootstrap for Combating Label Noise

Deep neural networks are powerful tools for representation learning, but can easily overfit to noisy labels which are prevalent in many real-world scenarios. Generally, noisy supervision could stem from variation among labelers, label corruption by adversaries, etc. To combat such label noises, one popular line of approach is to apply customized weights to the training instances, so that the corrupted examples contribute less to the model learning. However, such learning mechanisms potentially erase important information about the data distribution and therefore yield suboptimal results. To leverage useful information from the corrupted instances, an alternative is the bootstrapping loss, which reconstructs new training targets on-the-fly by incorporating the network's own predictions (i.e., pseudo-labels). In this paper, we propose a more generic learnable loss objective which enables a joint reweighting of instances and labels at once. Specifically, our method dynamically adjusts the per-sample importance weight between the real observed labels and pseudo-labels, where the weights are efficiently determined in a meta process. Compared to the previous instance reweighting methods, our approach concurrently conducts implicit relabeling, and thereby yield substantial improvements with almost no extra cost. Extensive experimental results demonstrated the strengths of our approach over existing methods on multiple natural and medical image benchmark datasets, including CIFAR-10, CIFAR-100, ISIC2019 and Clothing 1M. The code is publicly available at https://github.com/yuyinzhou/L2B.