RAU: Reference-based Anatomical Understanding with Vision Language Models

Anatomical understanding through deep learning is critical for automatic report generation, intra-operative navigation, and organ localization in medical imaging; however, its progress is constrained by the scarcity of expert-labeled data. A promising remedy is to leverage an annotated reference image to guide the interpretation of an unlabeled target. Although recent vision-language models (VLMs) exhibit non-trivial visual reasoning, their reference-based understanding and fine-grained localization remain limited. We introduce RAU, a framework for reference-based anatomical understanding with VLMs. We first show that a VLM learns to identify anatomical regions through relative spatial reasoning between reference and target images, trained on a moderately sized dataset. We validate this capability through visual question answering (VQA) and bounding box prediction. Next, we demonstrate that the VLM-derived spatial cues can be seamlessly integrated with the fine-grained segmentation capability of SAM2, enabling localization and pixel-level segmentation of small anatomical regions, such as vessel segments. Across two in-distribution and two out-of-distribution datasets, RAU consistently outperforms a SAM2 fine-tuning baseline using the same memory setup, yielding more accurate segmentations and more reliable localization. More importantly, its strong generalization ability makes it scalable to out-of-distribution datasets, a property crucial for medical image applications. To the best of our knowledge, RAU is the first to explore the capability of VLMs for reference-based identification, localization, and segmentation of anatomical structures in medical images. Its promising performance highlights the potential of VLM-driven approaches for anatomical understanding in automated clinical workflows.

TransforMARS: Fault-Tolerant Self-Reconfiguration for Arbitrarily Shaped Modular Aerial Robot Systems

Modular Aerial Robot Systems (MARS) consist of multiple drone modules that are physically bound together to form a single structure for flight. Exploiting structural redundancy, MARS can be reconfigured into different formations to mitigate unit or rotor failures and maintain stable flight. Prior work on MARS self-reconfiguration has solely focused on maximizing controllability margins to tolerate a single rotor or unit fault for rectangular-shaped MARS. We propose TransforMARS, a general fault-tolerant reconfiguration framework that transforms arbitrarily shaped MARS under multiple rotor and unit faults while ensuring continuous in-air stability. Specifically, we develop algorithms to first identify and construct minimum controllable assemblies containing faulty units. We then plan feasible disassembly-assembly sequences to transport MARS units or subassemblies to form target configuration. Our approach enables more flexible and practical feasible reconfiguration. We validate TransforMARS in challenging arbitrarily shaped MARS configurations, demonstrating substantial improvements over prior works in both the capacity of handling diverse configurations and the number of faults tolerated. The videos and source code of this work are available at the anonymous repository: https://anonymous.4open.science/r/TransforMARS-1030/

Learning Agile Gate Traversal via Analytical Optimal Policy Gradient

Traversing narrow gates presents a significant challenge and has become a standard benchmark for evaluating agile and precise quadrotor flight. Traditional modularized autonomous flight stacks require extensive design and parameter tuning, while end-to-end reinforcement learning (RL) methods often suffer from low sample efficiency and limited interpretability. In this work, we present a novel hybrid framework that adaptively fine-tunes model predictive control (MPC) parameters online using outputs from a neural network (NN) trained offline. The NN jointly predicts a reference pose and cost-function weights, conditioned on the coordinates of the gate corners and the current drone state. To achieve efficient training, we derive analytical policy gradients not only for the MPC module but also for an optimization-based gate traversal detection module. Furthermore, we introduce a new formulation of the attitude tracking error that admits a simplified representation, facilitating effective learning with bounded gradients. Hardware experiments demonstrate that our method enables fast and accurate quadrotor traversal through narrow gates in confined environments. It achieves several orders of magnitude improvement in sample efficiency compared to naive end-to-end RL approaches.

SIGN: Safety-Aware Image-Goal Navigation for Autonomous Drones via Reinforcement Learning

Image-goal navigation (ImageNav) tasks a robot with autonomously exploring an unknown environment and reaching a location that visually matches a given target image. While prior works primarily study ImageNav for ground robots, enabling this capability for autonomous drones is substantially more challenging due to their need for high-frequency feedback control and global localization for stable flight. In this paper, we propose a novel sim-to-real framework that leverages visual reinforcement learning (RL) to achieve ImageNav for drones. To enhance visual representation ability, our approach trains the vision backbone with auxiliary tasks, including image perturbations and future transition prediction, which results in more effective policy training. The proposed algorithm enables end-to-end ImageNav with direct velocity control, eliminating the need for external localization. Furthermore, we integrate a depth-based safety module for real-time obstacle avoidance, allowing the drone to safely navigate in cluttered environments. Unlike most existing drone navigation methods that focus solely on reference tracking or obstacle avoidance, our framework supports comprehensive navigation behaviors--autonomous exploration, obstacle avoidance, and image-goal seeking--without requiring explicit global mapping. Code and model checkpoints will be released upon acceptance.

FED-PsyAU: Privacy-Preserving Micro-Expression Recognition via Psychological AU Coordination and Dynamic Facial Motion Modeling

Micro-expressions (MEs) are brief, low-intensity, often localized facial expressions. They could reveal genuine emotions individuals may attempt to conceal, valuable in contexts like criminal interrogation and psychological counseling. However, ME recognition (MER) faces challenges, such as small sample sizes and subtle features, which hinder efficient modeling. Additionally, real-world applications encounter ME data privacy issues, leaving the task of enhancing recognition across settings under privacy constraints largely unexplored. To address these issues, we propose a FED-PsyAU research framework. We begin with a psychological study on the coordination of upper and lower facial action units (AUs) to provide structured prior knowledge of facial muscle dynamics. We then develop a DPK-GAT network that combines these psychological priors with statistical AU patterns, enabling hierarchical learning of facial motion features from regional to global levels, effectively enhancing MER performance. Additionally, our federated learning framework advances MER capabilities across multiple clients without data sharing, preserving privacy and alleviating the limited-sample issue for each client. Extensive experiments on commonly-used ME databases demonstrate the effectiveness of our approach.

CheXPO: Preference Optimization for Chest X-ray VLMs with Counterfactual Rationale

Vision-language models (VLMs) are prone to hallucinations that critically compromise reliability in medical applications. While preference optimization can mitigate these hallucinations through clinical feedback, its implementation faces challenges such as clinically irrelevant training samples, imbalanced data distributions, and prohibitive expert annotation costs. To address these challenges, we introduce CheXPO, a Chest X-ray Preference Optimization strategy that combines confidence-similarity joint mining with counterfactual rationale. Our approach begins by synthesizing a unified, fine-grained multi-task chest X-ray visual instruction dataset across different question types for supervised fine-tuning (SFT). We then identify hard examples through token-level confidence analysis of SFT failures and use similarity-based retrieval to expand hard examples for balancing preference sample distributions, while synthetic counterfactual rationales provide fine-grained clinical preferences, eliminating the need for additional expert input. Experiments show that CheXPO achieves 8.93% relative performance gain using only 5% of SFT samples, reaching state-of-the-art performance across diverse clinical tasks and providing a scalable, interpretable solution for real-world radiology applications.

Towards a general-purpose foundation model for fMRI analysis

Functional Magnetic Resonance Imaging (fMRI) is essential for studying brain function and diagnosing neurological disorders, but current analysis methods face reproducibility and transferability issues due to complex pre-processing and task-specific models. We introduce NeuroSTORM (Neuroimaging Foundation Model with Spatial-Temporal Optimized Representation Modeling), a generalizable framework that directly learns from 4D fMRI volumes and enables efficient knowledge transfer across diverse applications. NeuroSTORM is pre-trained on 28.65 million fMRI frames (>9,000 hours) from over 50,000 subjects across multiple centers and ages 5 to 100. Using a Mamba backbone and a shifted scanning strategy, it efficiently processes full 4D volumes. We also propose a spatial-temporal optimized pre-training approach and task-specific prompt tuning to improve transferability. NeuroSTORM outperforms existing methods across five tasks: age/gender prediction, phenotype prediction, disease diagnosis, fMRI-to-image retrieval, and task-based fMRI classification. It demonstrates strong clinical utility on datasets from hospitals in the U.S., South Korea, and Australia, achieving top performance in disease diagnosis and cognitive phenotype prediction. NeuroSTORM provides a standardized, open-source foundation model to improve reproducibility and transferability in fMRI-based clinical research.

Taming Diffusion for Dataset Distillation with High Representativeness

Recent deep learning models demand larger datasets, driving the need for dataset distillation to create compact, cost-efficient datasets while maintaining performance. Due to the powerful image generation capability of diffusion, it has been introduced to this field for generating distilled images. In this paper, we systematically investigate issues present in current diffusion-based dataset distillation methods, including inaccurate distribution matching, distribution deviation with random noise, and separate sampling. Building on this, we propose D^3HR, a novel diffusion-based framework to generate distilled datasets with high representativeness. Specifically, we adopt DDIM inversion to map the latents of the full dataset from a low-normality latent domain to a high-normality Gaussian domain, preserving information and ensuring structural consistency to generate representative latents for the distilled dataset. Furthermore, we propose an efficient sampling scheme to better align the representative latents with the high-normality Gaussian distribution. Our comprehensive experiments demonstrate that D^3HR can achieve higher accuracy across different model architectures compared with state-of-the-art baselines in dataset distillation. Source code: https://github.com/lin-zhao-resoLve/D3HR.

Object-Focus Actor for Data-efficient Robot Generalization Dexterous Manipulation

Robot manipulation learning from human demonstrations offers a rapid means to acquire skills but often lacks generalization across diverse scenes and object placements. This limitation hinders real-world applications, particularly in complex tasks requiring dexterous manipulation. Vision-Language-Action (VLA) paradigm leverages large-scale data to enhance generalization. However, due to data scarcity, VLA's performance remains limited. In this work, we introduce Object-Focus Actor (OFA), a novel, data-efficient approach for generalized dexterous manipulation. OFA exploits the consistent end trajectories observed in dexterous manipulation tasks, allowing for efficient policy training. Our method employs a hierarchical pipeline: object perception and pose estimation, pre-manipulation pose arrival and OFA policy execution. This process ensures that the manipulation is focused and efficient, even in varied backgrounds and positional layout. Comprehensive real-world experiments across seven tasks demonstrate that OFA significantly outperforms baseline methods in both positional and background generalization tests. Notably, OFA achieves robust performance with only 10 demonstrations, highlighting its data efficiency.

Taming OOD Actions for Offline Reinforcement Learning: An Advantage-Based Approach

Offline reinforcement learning (RL) aims to learn decision-making policies from fixed datasets without online interactions, providing a practical solution where online data collection is expensive or risky. However, offline RL often suffers from distribution shift, resulting in inaccurate evaluation and substantial overestimation on out-of-distribution (OOD) actions. To address this, existing approaches incorporate conservatism by indiscriminately discouraging all OOD actions, thereby hindering the agent's ability to generalize and exploit beneficial ones. In this paper, we propose Advantage-based Diffusion Actor-Critic (ADAC), a novel method that systematically evaluates OOD actions using the batch-optimal value function. Based on this evaluation, ADAC defines an advantage function to modulate the Q-function update, enabling more precise assessment of OOD action quality. We design a custom PointMaze environment and collect datasets to visually reveal that advantage modulation can effectively identify and select superior OOD actions. Extensive experiments show that ADAC achieves state-of-the-art performance on almost all tasks in the D4RL benchmark, with particularly clear margins on the more challenging tasks.