Object-Focus Actor for Data-efficient Robot Generalization Dexterous Manipulation

Robot manipulation learning from human demonstrations offers a rapid means to acquire skills but often lacks generalization across diverse scenes and object placements. This limitation hinders real-world applications, particularly in complex tasks requiring dexterous manipulation. Vision-Language-Action (VLA) paradigm leverages large-scale data to enhance generalization. However, due to data scarcity, VLA's performance remains limited. In this work, we introduce Object-Focus Actor (OFA), a novel, data-efficient approach for generalized dexterous manipulation. OFA exploits the consistent end trajectories observed in dexterous manipulation tasks, allowing for efficient policy training. Our method employs a hierarchical pipeline: object perception and pose estimation, pre-manipulation pose arrival and OFA policy execution. This process ensures that the manipulation is focused and efficient, even in varied backgrounds and positional layout. Comprehensive real-world experiments across seven tasks demonstrate that OFA significantly outperforms baseline methods in both positional and background generalization tests. Notably, OFA achieves robust performance with only 10 demonstrations, highlighting its data efficiency.

Shadow-FT: Tuning Instruct via Base

Large language models (LLMs) consistently benefit from further fine-tuning on various tasks. However, we observe that directly tuning the INSTRUCT (i.e., instruction tuned) models often leads to marginal improvements and even performance degeneration. Notably, paired BASE models, the foundation for these INSTRUCT variants, contain highly similar weight values (i.e., less than 2% on average for Llama 3.1 8B). Therefore, we propose a novel Shadow-FT framework to tune the INSTRUCT models by leveraging the corresponding BASE models. The key insight is to fine-tune the BASE model, and then directly graft the learned weight updates to the INSTRUCT model. Our proposed Shadow-FT introduces no additional parameters, is easy to implement, and significantly improves performance. We conduct extensive experiments on tuning mainstream LLMs, such as Qwen 3 and Llama 3 series, and evaluate them across 19 benchmarks covering coding, reasoning, and mathematical tasks. Experimental results demonstrate that Shadow-FT consistently outperforms conventional full-parameter and parameter-efficient tuning approaches. Further analyses indicate that Shadow-FT can be applied to multimodal large language models (MLLMs) and combined with direct preference optimization (DPO). Codes and weights are available at \href{https://github.com/wutaiqiang/Shadow-FT}{Github}.

DS-ProGen: A Dual-Structure Deep Language Model for Functional Protein Design

Inverse Protein Folding (IPF) is a critical subtask in the field of protein design, aiming to engineer amino acid sequences capable of folding correctly into a specified three-dimensional (3D) conformation. Although substantial progress has been achieved in recent years, existing methods generally rely on either backbone coordinates or molecular surface features alone, which restricts their ability to fully capture the complex chemical and geometric constraints necessary for precise sequence prediction. To address this limitation, we present DS-ProGen, a dual-structure deep language model for functional protein design, which integrates both backbone geometry and surface-level representations. By incorporating backbone coordinates as well as surface chemical and geometric descriptors into a next-amino-acid prediction paradigm, DS-ProGen is able to generate functionally relevant and structurally stable sequences while satisfying both global and local conformational constraints. On the PRIDE dataset, DS-ProGen attains the current state-of-the-art recovery rate of 61.47%, demonstrating the synergistic advantage of multi-modal structural encoding in protein design. Furthermore, DS-ProGen excels in predicting interactions with a variety of biological partners, including ligands, ions, and RNA, confirming its robust functional retention capabilities.

A Tale of Two Identities: An Ethical Audit of Human and AI-Crafted Personas

As LLMs (large language models) are increasingly used to generate synthetic personas particularly in data-limited domains such as health, privacy, and HCI, it becomes necessary to understand how these narratives represent identity, especially that of minority communities. In this paper, we audit synthetic personas generated by 3 LLMs (GPT4o, Gemini 1.5 Pro, Deepseek 2.5) through the lens of representational harm, focusing specifically on racial identity. Using a mixed methods approach combining close reading, lexical analysis, and a parameterized creativity framework, we compare 1512 LLM generated personas to human-authored responses. Our findings reveal that LLMs disproportionately foreground racial markers, overproduce culturally coded language, and construct personas that are syntactically elaborate yet narratively reductive. These patterns result in a range of sociotechnical harms, including stereotyping, exoticism, erasure, and benevolent bias, that are often obfuscated by superficially positive narrations. We formalize this phenomenon as algorithmic othering, where minoritized identities are rendered hypervisible but less authentic. Based on these findings, we offer design recommendations for narrative-aware evaluation metrics and community-centered validation protocols for synthetic identity generation.

Can Third-parties Read Our Emotions?

Natural Language Processing tasks that aim to infer an author's private states, e.g., emotions and opinions, from their written text, typically rely on datasets annotated by third-party annotators. However, the assumption that third-party annotators can accurately capture authors' private states remains largely unexamined. In this study, we present human subjects experiments on emotion recognition tasks that directly compare third-party annotations with first-party (author-provided) emotion labels. Our findings reveal significant limitations in third-party annotations-whether provided by human annotators or large language models (LLMs)-in faithfully representing authors' private states. However, LLMs outperform human annotators nearly across the board. We further explore methods to improve third-party annotation quality. We find that demographic similarity between first-party authors and third-party human annotators enhances annotation performance. While incorporating first-party demographic information into prompts leads to a marginal but statistically significant improvement in LLMs' performance. We introduce a framework for evaluating the limitations of third-party annotations and call for refined annotation practices to accurately represent and model authors' private states.

Unity RL Playground: A Versatile Reinforcement Learning Framework for Mobile Robots

This paper introduces Unity RL Playground, an open-source reinforcement learning framework built on top of Unity ML-Agents. Unity RL Playground automates the process of training mobile robots to perform various locomotion tasks such as walking, running, and jumping in simulation, with the potential for seamless transfer to real hardware. Key features include one-click training for imported robot models, universal compatibility with diverse robot configurations, multi-mode motion learning capabilities, and extreme performance testing to aid in robot design optimization and morphological evolution. The attached video can be found at https://linqi-ye.github.io/video/iros25.mp4 and the code is coming soon.

Dexterous Hand Manipulation via Efficient Imitation-Bootstrapped Online Reinforcement Learning

Dexterous hand manipulation in real-world scenarios presents considerable challenges due to its demands for both dexterity and precision. While imitation learning approaches have thoroughly examined these challenges, they still require a significant number of expert demonstrations and are limited by a constrained performance upper bound. In this paper, we propose a novel and efficient Imitation-Bootstrapped Online Reinforcement Learning (IBORL) method tailored for robotic dexterous hand manipulation in real-world environments. Specifically, we pretrain the policy using a limited set of expert demonstrations and subsequently finetune this policy through direct reinforcement learning in the real world. To address the catastrophic forgetting issues that arise from the distribution shift between expert demonstrations and real-world environments, we design a regularization term that balances the exploration of novel behaviors with the preservation of the pretrained policy. Our experiments with real-world tasks demonstrate that our method significantly outperforms existing approaches, achieving an almost 100% success rate and a 23% improvement in cycle time. Furthermore, by finetuning with online reinforcement learning, our method surpasses expert demonstrations and uncovers superior policies. Our code and empirical results are available in https://hggforget.github.io/iborl.github.io/.

Biological Sequence with Language Model Prompting: A Survey

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis and synthesis, attracting widespread attention from academics and medicine. In this paper, we systematically investigate the application of prompt-based methods with LLMs to biological sequences, including DNA, RNA, proteins, and drug discovery tasks. Specifically, we focus on how prompt engineering enables LLMs to tackle domain-specific problems, such as promoter sequence prediction, protein structure modeling, and drug-target binding affinity prediction, often with limited labeled data. Furthermore, our discussion highlights the transformative potential of prompting in bioinformatics while addressing key challenges such as data scarcity, multimodal fusion, and computational resource limitations. Our aim is for this paper to function both as a foundational primer for newcomers and a catalyst for continued innovation within this dynamic field of study.

Haste Makes Waste: Evaluating Planning Abilities of LLMs for Efficient and Feasible Multitasking with Time Constraints Between Actions

While Large Language Model-based agents have demonstrated substantial progress in task completion, existing evaluation benchmarks tend to overemphasize single-task performance, with insufficient attention given to the crucial aspects of multitask planning and execution efficiency required in real-world scenarios. To bridge this gap, we present Recipe2Plan, a novel benchmark framework based on real-world cooking scenarios. Unlike conventional benchmarks, Recipe2Plan challenges agents to optimize cooking time through parallel task execution while respecting temporal constraints i.e. specific actions need to be performed within a particular time intervals following the preceding steps. Overly aggressive local parallelization may disrupt this constraint, potentially compromising the entire cooking process. This strict time constraint between actions raises a unique challenge for agents to balance between maximizing concurrent operations and adhering to critical timing constraints. Extensive experiments with state-of-the-art models reveal challenges in maintaining this balance between efficiency and feasibility. The results highlight the need for improved temporal awareness and global multitasking capabilities in large language models. We open-source our benchmark and code at https://github.com/WilliamZR/Recipe2Plan.

Automated Annotation of Evolving Corpora for Augmenting Longitudinal Network Data: A Framework Integrating Large Language Models and Expert Knowledge

Longitudinal network data are essential for analyzing political, economic, and social systems and processes. In political science, these datasets are often generated through human annotation or supervised machine learning applied to evolving corpora. However, as semantic contexts shift over time, inferring dynamic interaction types on emerging issues among a diverse set of entities poses significant challenges, particularly in maintaining timely and consistent annotations. This paper presents the Expert-Augmented LLM Annotation (EALA) approach, which leverages Large Language Models (LLMs) in combination with historically annotated data and expert-constructed codebooks to extrapolate and extend datasets into future periods. We evaluate the performance and reliability of EALA using a dataset of climate negotiations. Our findings demonstrate that EALA effectively predicts nuanced interactions between negotiation parties and captures the evolution of topics over time. At the same time, we identify several limitations inherent to LLM-based annotation, highlighting areas for further improvement. Given the wide availability of codebooks and annotated datasets, EALA holds substantial promise for advancing research in political science and beyond.