Learning Socio-Temporal Graphs for Multi-Agent Trajectory Prediction

In order to predict a pedestrian's trajectory in a crowd accurately, one has to take into account her/his underlying socio-temporal interactions with other pedestrians consistently. Unlike existing work that represents the relevant information separately, partially, or implicitly, we propose a complete representation for it to be fully and explicitly captured and analyzed. In particular, we introduce a Directed Acyclic Graph-based structure, which we term Socio-Temporal Graph (STG), to explicitly capture pair-wise socio-temporal interactions among a group of people across both space and time. Our model is built on a time-varying generative process, whose latent variables determine the structure of the STGs. We design an attention-based model named STGformer that affords an end-to-end pipeline to learn the structure of the STGs for trajectory prediction. Our solution achieves overall state-of-the-art prediction accuracy in two large-scale benchmark datasets. Our analysis shows that a person's past trajectory is critical for predicting another person's future path. Our model learns this relationship with a strong notion of socio-temporal localities. Statistics show that utilizing this information explicitly for prediction yields a noticeable performance gain with respect to the trajectory-only approaches.

S$^3$-TTA: Scale-Style Selection for Test-Time Augmentation in Biomedical Image Segmentation

Deep-learning models have been successful in biomedical image segmentation. To generalize for real-world deployment, test-time augmentation (TTA) methods are often used to transform the test image into different versions that are hopefully closer to the training domain. Unfortunately, due to the vast diversity of instance scale and image styles, many augmented test images produce undesirable results, thus lowering the overall performance. This work proposes a new TTA framework, S$^3$-TTA, which selects the suitable image scale and style for each test image based on a transformation consistency metric. In addition, S$^3$-TTA constructs an end-to-end augmentation-segmentation joint-training pipeline to ensure a task-oriented augmentation. On public benchmarks for cell and lung segmentation, S$^3$-TTA demonstrates improvements over the prior art by 3.4% and 1.3%, respectively, by simply augmenting the input data in testing phase.

Structure-Preserving Instance Segmentation via Skeleton-Aware Distance Transform

Objects with complex structures pose significant challenges to existing instance segmentation methods that rely on boundary or affinity maps, which are vulnerable to small errors around contacting pixels that cause noticeable connectivity change. While the distance transform (DT) makes instance interiors and boundaries more distinguishable, it tends to overlook the intra-object connectivity for instances with varying width and result in over-segmentation. To address these challenges, we propose a skeleton-aware distance transform (SDT) that combines the merits of object skeleton in preserving connectivity and DT in modeling geometric arrangement to represent instances with arbitrary structures. Comprehensive experiments on histopathology image segmentation demonstrate that SDT achieves state-of-the-art performance.

Efficient Anatomical Labeling of Pulmonary Tree Structures via Implicit Point-Graph Networks

Pulmonary diseases rank prominently among the principal causes of death worldwide. Curing them will require, among other things, a better understanding of the many complex 3D tree-shaped structures within the pulmonary system, such as airways, arteries, and veins. In theory, they can be modeled using high-resolution image stacks. Unfortunately, standard CNN approaches operating on dense voxel grids are prohibitively expensive. To remedy this, we introduce a point-based approach that preserves graph connectivity of tree skeleton and incorporates an implicit surface representation. It delivers SOTA accuracy at a low computational cost and the resulting models have usable surfaces. Due to the scarcity of publicly accessible data, we have also curated an extensive dataset to evaluate our approach and will make it public.

CLIPTrans: Transferring Visual Knowledge with Pre-trained Models for Multimodal Machine Translation

There has been a growing interest in developing multimodal machine translation (MMT) systems that enhance neural machine translation (NMT) with visual knowledge. This problem setup involves using images as auxiliary information during training, and more recently, eliminating their use during inference. Towards this end, previous works face a challenge in training powerful MMT models from scratch due to the scarcity of annotated multilingual vision-language data, especially for low-resource languages. Simultaneously, there has been an influx of multilingual pre-trained models for NMT and multimodal pre-trained models for vision-language tasks, primarily in English, which have shown exceptional generalisation ability. However, these are not directly applicable to MMT since they do not provide aligned multimodal multilingual features for generative tasks. To alleviate this issue, instead of designing complex modules for MMT, we propose CLIPTrans, which simply adapts the independently pre-trained multimodal M-CLIP and the multilingual mBART. In order to align their embedding spaces, mBART is conditioned on the M-CLIP features by a prefix sequence generated through a lightweight mapping network. We train this in a two-stage pipeline which warms up the model with image captioning before the actual translation task. Through experiments, we demonstrate the merits of this framework and consequently push forward the state-of-the-art across standard benchmarks by an average of +2.67 BLEU. The code can be found at www.github.com/devaansh100/CLIPTrans.

Domain-Scalable Unpaired Image Translation via Latent Space Anchoring

Unpaired image-to-image translation (UNIT) aims to map images between two visual domains without paired training data. However, given a UNIT model trained on certain domains, it is difficult for current methods to incorporate new domains because they often need to train the full model on both existing and new domains. To address this problem, we propose a new domain-scalable UNIT method, termed as latent space anchoring, which can be efficiently extended to new visual domains and does not need to fine-tune encoders and decoders of existing domains. Our method anchors images of different domains to the same latent space of frozen GANs by learning lightweight encoder and regressor models to reconstruct single-domain images. In the inference phase, the learned encoders and decoders of different domains can be arbitrarily combined to translate images between any two domains without fine-tuning. Experiments on various datasets show that the proposed method achieves superior performance on both standard and domain-scalable UNIT tasks in comparison with the state-of-the-art methods.

The Impact of ChatGPT and LLMs on Medical Imaging Stakeholders: Perspectives and Use Cases

This study investigates the transformative potential of Large Language Models (LLMs), such as OpenAI ChatGPT, in medical imaging. With the aid of public data, these models, which possess remarkable language understanding and generation capabilities, are augmenting the interpretive skills of radiologists, enhancing patient-physician communication, and streamlining clinical workflows. The paper introduces an analytic framework for presenting the complex interactions between LLMs and the broader ecosystem of medical imaging stakeholders, including businesses, insurance entities, governments, research institutions, and hospitals (nicknamed BIGR-H). Through detailed analyses, illustrative use cases, and discussions on the broader implications and future directions, this perspective seeks to raise discussion in strategic planning and decision-making in the era of AI-enabled healthcare.

Calibrating Cross-modal Feature for Text-Based Person Searching

We present a novel and effective method calibrating cross-modal features for text-based person search. Our method is cost-effective and can easily retrieve specific persons with textual captions. Specifically, its architecture is only a dual-encoder and a detachable cross-modal decoder. Without extra multi-level branches or complex interaction modules as the neck following the backbone, our model makes a high-speed inference only based on the dual-encoder. Besides, our method consists of two novel losses to provide fine-grained cross-modal features. A Sew loss takes the quality of textual captions as guidance and aligns features between image and text modalities. A Masking Caption Modeling (MCM) loss uses a masked captions prediction task to establish detailed and generic relationships between textual and visual parts. We show the top results in three popular benchmarks, including CUHK-PEDES, ICFG-PEDES, and RSTPReID. In particular, our method achieves 73.81% Rank@1, 74.25% Rank@1 and 57.35% Rank@1 on them, respectively. In addition, we also validate each component of our method with extensive experiments. We hope our powerful and scalable paradigm will serve as a solid baseline and help ease future research in text-based person search.

Why is the winner the best?

International benchmarking competitions have become fundamental for the comparative performance assessment of image analysis methods. However, little attention has been given to investigating what can be learnt from these competitions. Do they really generate scientific progress? What are common and successful participation strategies? What makes a solution superior to a competing method? To address this gap in the literature, we performed a multi-center study with all 80 competitions that were conducted in the scope of IEEE ISBI 2021 and MICCAI 2021. Statistical analyses performed based on comprehensive descriptions of the submitted algorithms linked to their rank as well as the underlying participation strategies revealed common characteristics of winning solutions. These typically include the use of multi-task learning (63%) and/or multi-stage pipelines (61%), and a focus on augmentation (100%), image preprocessing (97%), data curation (79%), and postprocessing (66%). The "typical" lead of a winning team is a computer scientist with a doctoral degree, five years of experience in biomedical image analysis, and four years of experience in deep learning. Two core general development strategies stood out for highly-ranked teams: the reflection of the metrics in the method design and the focus on analyzing and handling failure cases. According to the organizers, 43% of the winning algorithms exceeded the state of the art but only 11% completely solved the respective domain problem. The insights of our study could help researchers (1) improve algorithm development strategies when approaching new problems, and (2) focus on open research questions revealed by this work.

The XPRESS Challenge: Xray Projectomic Reconstruction -- Extracting Segmentation with Skeletons

The wiring and connectivity of neurons form a structural basis for the function of the nervous system. Advances in volume electron microscopy (EM) and image segmentation have enabled mapping of circuit diagrams (connectomics) within local regions of the mouse brain. However, applying volume EM over the whole brain is not currently feasible due to technological challenges. As a result, comprehensive maps of long-range connections between brain regions are lacking. Recently, we demonstrated that X-ray holographic nanotomography (XNH) can provide high-resolution images of brain tissue at a much larger scale than EM. In particular, XNH is wellsuited to resolve large, myelinated axon tracts (white matter) that make up the bulk of long-range connections (projections) and are critical for inter-region communication. Thus, XNH provides an imaging solution for brain-wide projectomics. However, because XNH data is typically collected at lower resolutions and larger fields-of-view than EM, accurate segmentation of XNH images remains an important challenge that we present here. In this task, we provide volumetric XNH images of cortical white matter axons from the mouse brain along with ground truth annotations for axon trajectories. Manual voxel-wise annotation of ground truth is a time-consuming bottleneck for training segmentation networks. On the other hand, skeleton-based ground truth is much faster to annotate, and sufficient to determine connectivity. Therefore, we encourage participants to develop methods to leverage skeleton-based training. To this end, we provide two types of ground-truth annotations: a small volume of voxel-wise annotations and a larger volume with skeleton-based annotations. Entries will be evaluated on how accurately the submitted segmentations agree with the ground-truth skeleton annotations.