Are Multimodal Large Language Models Ready for Omnidirectional Spatial Reasoning?

The 180x360 omnidirectional field of view captured by 360-degree cameras enables their use in a wide range of applications such as embodied AI and virtual reality. Although recent advances in multimodal large language models (MLLMs) have shown promise in visual-spatial reasoning, most studies focus on standard pinhole-view images, leaving omnidirectional perception largely unexplored. In this paper, we ask: Are MLLMs ready for omnidirectional spatial reasoning? To investigate this, we introduce OSR-Bench, the first benchmark specifically designed for this setting. OSR-Bench includes over 153,000 diverse question-answer pairs grounded in high-fidelity panoramic indoor scene maps. It covers key reasoning types including object counting, relative distance, and direction. We also propose a negative sampling strategy that inserts non-existent objects into prompts to evaluate hallucination and grounding robustness. For fine-grained analysis, we design a two-stage evaluation framework assessing both cognitive map generation and QA accuracy using rotation-invariant matching and a combination of rule-based and LLM-based metrics. We evaluate eight state-of-the-art MLLMs, including GPT-4o, Gemini 1.5 Pro, and leading open-source models under zero-shot settings. Results show that current models struggle with spatial reasoning in panoramic contexts, highlighting the need for more perceptually grounded MLLMs. OSR-Bench and code will be released at: https://huggingface.co/datasets/UUUserna/OSR-Bench

Efficient 4D fMRI ASD Classification using Spatial-Temporal-Omics-based Learning Framework

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder impacting social and behavioral development. Resting-state fMRI, a non-invasive tool for capturing brain connectivity patterns, aids in early ASD diagnosis and differentiation from typical controls (TC). However, previous methods, which rely on either mean time series or full 4D data, are limited by a lack of spatial information or by high computational costs. This underscores the need for an efficient solution that preserves both spatial and temporal information. In this paper, we propose a novel, simple, and efficient spatial-temporal-omics learning framework designed to efficiently extract spatio-temporal features from fMRI for ASD classification. Our approach addresses these limitations by utilizing 3D time-domain derivatives as the spatial-temporal inter-voxel omics, which preserve full spatial resolution while capturing diverse statistical characteristics of the time series at each voxel. Meanwhile, functional connectivity features serve as the spatial-temporal inter-regional omics, capturing correlations across brain regions. Extensive experiments and ablation studies on the ABIDE dataset demonstrate that our framework significantly outperforms previous methods while maintaining computational efficiency. We believe our research offers valuable insights that will inform and advance future ASD studies, particularly in the realm of spatial-temporal-omics-based learning.

Efficient Anatomical Labeling of Pulmonary Tree Structures via Implicit Point-Graph Networks

Pulmonary diseases rank prominently among the principal causes of death worldwide. Curing them will require, among other things, a better understanding of the many complex 3D tree-shaped structures within the pulmonary system, such as airways, arteries, and veins. In theory, they can be modeled using high-resolution image stacks. Unfortunately, standard CNN approaches operating on dense voxel grids are prohibitively expensive. To remedy this, we introduce a point-based approach that preserves graph connectivity of tree skeleton and incorporates an implicit surface representation. It delivers SOTA accuracy at a low computational cost and the resulting models have usable surfaces. Due to the scarcity of publicly accessible data, we have also curated an extensive dataset to evaluate our approach and will make it public.

Topology Repairing of Disconnected Pulmonary Airways and Vessels: Baselines and a Dataset

Accurate segmentation of pulmonary airways and vessels is crucial for the diagnosis and treatment of pulmonary diseases. However, current deep learning approaches suffer from disconnectivity issues that hinder their clinical usefulness. To address this challenge, we propose a post-processing approach that leverages a data-driven method to repair the topology of disconnected pulmonary tubular structures. Our approach formulates the problem as a keypoint detection task, where a neural network is trained to predict keypoints that can bridge disconnected components. We use a training data synthesis pipeline that generates disconnected data from complete pulmonary structures. Moreover, the new Pulmonary Tree Repairing (PTR) dataset is publicly available, which comprises 800 complete 3D models of pulmonary airways, arteries, and veins, as well as the synthetic disconnected data. Our code and data are available at https://github.com/M3DV/pulmonary-tree-repairing.