LOOK-M: Look-Once Optimization in KV Cache for Efficient Multimodal Long-Context Inference

Long-context Multimodal Large Language Models (MLLMs) demand substantial computational resources for inference as the growth of their multimodal Key-Value (KV) cache, in response to increasing input lengths, challenges memory and time efficiency. Unlike single-modality LLMs that manage only textual contexts, the KV cache of long-context MLLMs includes representations from multiple images with temporal and spatial relationships and related textual contexts. The predominance of image tokens means traditional optimizations for LLMs' KV caches are unsuitable for multimodal long-context settings, and no prior works have addressed this challenge. In this work, we introduce LOOK-M, a pioneering, fine-tuning-free approach that efficiently reduces the multimodal KV cache size while maintaining performance comparable to a full cache. We observe that during prompt prefill, the model prioritizes more textual attention over image features, and based on the multimodal interaction observation, a new proposed text-prior method is explored to compress the KV cache. Furthermore, to mitigate the degradation of image contextual information, we propose several compensatory strategies using KV pairs merging. LOOK-M demonstrates that with a significant reduction in KV Cache memory usage, such as reducing it by 80% in some cases, it not only achieves up to 1.5x faster decoding but also maintains or even enhances performance across a variety of long context multimodal tasks.

Benchmarking and Boosting Radiology Report Generation for 3D High-Resolution Medical Images

Automatic radiology report generation can significantly benefit the labor-intensive process of report writing by radiologists, especially for 3D radiographs like CT scans, which are crucial for broad clinical diagnostics yet underexplored compared to 2D radiographs. Existing methods often handle 3D volumes either slice-wise or with aggressive downsampling due to current GPU memory limitations, which results in a loss of the inherent 3D nature and critical details. To overcome these issues, we introduce a novel framework that efficiently and effectively generates radiology reports for high-resolution (HR) 3D volumes, based on large language models (LLMs). Specifically, our framework utilizes low-resolution (LR) visual tokens as queries to mine information from HR tokens, preserving detailed HR information while reducing computational costs by only processing HR informed LR visual queries. Further benefiting the field, we curate and release BIMCV-RG, a new dataset with 5,328 HR 3D volumes and paired reports, establishing the first benchmarks for report generation from 3D HR medical images. Our method consistently surpasses existing methods on this benchmark across three different settings: normal-resolution, high-resolution inputs, and zero-shot domain transfer, all at an acceptable computational cost, trainable on a single A100-80G.

Reverse the auditory processing pathway: Coarse-to-fine audio reconstruction from fMRI

Drawing inspiration from the hierarchical processing of the human auditory system, which transforms sound from low-level acoustic features to high-level semantic understanding, we introduce a novel coarse-to-fine audio reconstruction method. Leveraging non-invasive functional Magnetic Resonance Imaging (fMRI) data, our approach mimics the inverse pathway of auditory processing. Initially, we utilize CLAP to decode fMRI data coarsely into a low-dimensional semantic space, followed by a fine-grained decoding into the high-dimensional AudioMAE latent space guided by semantic features. These fine-grained neural features serve as conditions for audio reconstruction through a Latent Diffusion Model (LDM). Validation on three public fMRI datasets-Brain2Sound, Brain2Music, and Brain2Speech-underscores the superiority of our coarse-to-fine decoding method over stand-alone fine-grained approaches, showcasing state-of-the-art performance in metrics like FD, FAD, and KL. Moreover, by employing semantic prompts during decoding, we enhance the quality of reconstructed audio when semantic features are suboptimal. The demonstrated versatility of our model across diverse stimuli highlights its potential as a universal brain-to-audio framework. This research contributes to the comprehension of the human auditory system, pushing boundaries in neural decoding and audio reconstruction methodologies.

Open-vocabulary Auditory Neural Decoding Using fMRI-prompted LLM

Decoding language information from brain signals represents a vital research area within brain-computer interfaces, particularly in the context of deciphering the semantic information from the fMRI signal. However, many existing efforts concentrate on decoding small vocabulary sets, leaving space for the exploration of open vocabulary continuous text decoding. In this paper, we introduce a novel method, the \textbf{Brain Prompt GPT (BP-GPT)}. By using the brain representation that is extracted from the fMRI as a prompt, our method can utilize GPT-2 to decode fMRI signals into stimulus text. Further, we introduce a text-to-text baseline and align the fMRI prompt to the text prompt. By introducing the text-to-text baseline, our BP-GPT can extract a more robust brain prompt and promote the decoding of pre-trained LLM. We evaluate our BP-GPT on the open-source auditory semantic decoding dataset and achieve a significant improvement up to $4.61\%$ on METEOR and $2.43\%$ on BERTScore across all the subjects compared to the state-of-the-art method. The experimental results demonstrate that using brain representation as a prompt to further drive LLM for auditory neural decoding is feasible and effective.

Inductive-Deductive Strategy Reuse for Multi-Turn Instructional Dialogues

Aligning large language models (LLMs) with human expectations requires high-quality instructional dialogues, which can be achieved by raising diverse, in-depth, and insightful instructions that deepen interactions. Existing methods target instructions from real instruction dialogues as a learning goal and fine-tune a user simulator for posing instructions. However, the user simulator struggles to implicitly model complex dialogue flows and pose high-quality instructions. In this paper, we take inspiration from the cognitive abilities inherent in human learning and propose the explicit modeling of complex dialogue flows through instructional strategy reuse. Specifically, we first induce high-level strategies from various real instruction dialogues. These strategies are applied to new dialogue scenarios deductively, where the instructional strategies facilitate high-quality instructions. Experimental results show that our method can generate diverse, in-depth, and insightful instructions for a given dialogue history. The constructed multi-turn instructional dialogues can outperform competitive baselines on the downstream chat model.

BIMCV-R: A Landmark Dataset for 3D CT Text-Image Retrieval

The burgeoning integration of 3D medical imaging into healthcare has led to a substantial increase in the workload of medical professionals. To assist clinicians in their diagnostic processes and alleviate their workload, the development of a robust system for retrieving similar case studies presents a viable solution. While the concept holds great promise, the field of 3D medical text-image retrieval is currently limited by the absence of robust evaluation benchmarks and curated datasets. To remedy this, our study presents a groundbreaking dataset, BIMCV-R (This dataset will be released upon acceptance.), which includes an extensive collection of 8,069 3D CT volumes, encompassing over 2 million slices, paired with their respective radiological reports. Expanding upon the foundational work of our dataset, we craft a retrieval strategy, MedFinder. This approach employs a dual-stream network architecture, harnessing the potential of large language models to advance the field of medical image retrieval beyond existing text-image retrieval solutions. It marks our preliminary step towards developing a system capable of facilitating text-to-image, image-to-text, and keyword-based retrieval tasks.

Electrocardiogram Instruction Tuning for Report Generation

Electrocardiogram (ECG) serves as the primary non-invasive diagnostic tool for cardiac conditions monitoring, are crucial in assisting clinicians. Recent studies have concentrated on classifying cardiac conditions using ECG data but have overlooked ECG report generation, which is not only time-consuming but also requires clinical expertise. To automate ECG report generation and ensure its versatility, we propose the Multimodal ECG Instruction Tuning (MEIT) framework, the \textit{first} attempt to tackle ECG report generation with LLMs and multimodal instructions. To facilitate future research, we establish a benchmark to evaluate MEIT with various LLMs backbones across two large-scale ECG datasets. Our approach uniquely aligns the representations of the ECG signal and the report, and we conduct extensive experiments to benchmark MEIT with nine open source LLMs, using more than 800,000 ECG reports. MEIT's results underscore the superior performance of instruction-tuned LLMs, showcasing their proficiency in quality report generation, zero-shot capabilities, and resilience to signal perturbation. These findings emphasize the efficacy of our MEIT framework and its potential for real-world clinical application.

Zero-Shot ECG Classification with Multimodal Learning and Test-time Clinical Knowledge Enhancement

Electrocardiograms (ECGs) are non-invasive diagnostic tools crucial for detecting cardiac arrhythmic diseases in clinical practice. While ECG Self-supervised Learning (eSSL) methods show promise in representation learning from unannotated ECG data, they often overlook the clinical knowledge that can be found in reports. This oversight and the requirement for annotated samples for downstream tasks limit eSSL's versatility. In this work, we address these issues with the Multimodal ECG Representation Learning (MERL}) framework. Through multimodal learning on ECG records and associated reports, MERL is capable of performing zero-shot ECG classification with text prompts, eliminating the need for training data in downstream tasks. At test time, we propose the Clinical Knowledge Enhanced Prompt Engineering (CKEPE) approach, which uses Large Language Models (LLMs) to exploit external expert-verified clinical knowledge databases, generating more descriptive prompts and reducing hallucinations in LLM-generated content to boost zero-shot classification. Based on MERL, we perform the first benchmark across six public ECG datasets, showing the superior performance of MERL compared against eSSL methods. Notably, MERL achieves an average AUC score of 75.2% in zero-shot classification (without training data), 3.2% higher than linear probed eSSL methods with 10\% annotated training data, averaged across all six datasets.

ARKS: Active Retrieval in Knowledge Soup for Code Generation

Recently the retrieval-augmented generation (RAG) paradigm has raised much attention for its potential in incorporating external knowledge into large language models (LLMs) without further training. While widely explored in natural language applications, its utilization in code generation remains under-explored. In this paper, we introduce Active Retrieval in Knowledge Soup (ARKS), an advanced strategy for generalizing large language models for code. In contrast to relying on a single source, we construct a knowledge soup integrating web search, documentation, execution feedback, and evolved code snippets. We employ an active retrieval strategy that iteratively refines the query and updates the knowledge soup. To assess the performance of ARKS, we compile a new benchmark comprising realistic coding problems associated with frequently updated libraries and long-tail programming languages. Experimental results on ChatGPT and CodeLlama demonstrate a substantial improvement in the average execution accuracy of ARKS on LLMs. The analysis confirms the effectiveness of our proposed knowledge soup and active retrieval strategies, offering rich insights into the construction of effective retrieval-augmented code generation (RACG) pipelines. Our model, code, and data are available at https://arks-codegen.github.io.

Enhancing Role-playing Systems through Aggressive Queries: Evaluation and Improvement

The advent of Large Language Models (LLMs) has propelled dialogue generation into new realms, particularly in the field of role-playing systems (RPSs). While enhanced with ordinary role-relevant training dialogues, existing LLM-based RPSs still struggle to align with roles when handling intricate and trapped queries in boundary scenarios. In this paper, we design the Modular ORchestrated Trap-setting Interaction SystEm (MORTISE) to benchmark and improve the role-playing LLMs' performance. MORTISE can produce highly role-relevant aggressive queries through the collaborative effort of multiple LLM-based modules, and formulate corresponding responses to create an adversarial training dataset via a consistent response generator. We select 190 Chinese and English roles to construct aggressive queries to benchmark existing role-playing LLMs. Through comprehensive evaluation, we find that existing models exhibit a general deficiency in role alignment capabilities. We further select 180 of the roles to collect an adversarial training dataset (named RoleAD) and retain the other 10 roles for testing. Experiments on models improved by RoleAD indicate that our adversarial dataset ameliorates this deficiency, with the improvements demonstrating a degree of generalizability in ordinary scenarios.