MAPI-GNN: Multi-Activation Plane Interaction Graph Neural Network for Multimodal Medical Diagnosis

Graph neural networks are increasingly applied to multimodal medical diagnosis for their inherent relational modeling capabilities. However, their efficacy is often compromised by the prevailing reliance on a single, static graph built from indiscriminate features, hindering the ability to model patient-specific pathological relationships. To this end, the proposed Multi-Activation Plane Interaction Graph Neural Network (MAPI-GNN) reconstructs this single-graph paradigm by learning a multifaceted graph profile from semantically disentangled feature subspaces. The framework first uncovers latent graph-aware patterns via a multi-dimensional discriminator; these patterns then guide the dynamic construction of a stack of activation graphs; and this multifaceted profile is finally aggregated and contextualized by a relational fusion engine for a robust diagnosis. Extensive experiments on two diverse tasks, comprising over 1300 patient samples, demonstrate that MAPI-GNN significantly outperforms state-of-the-art methods.

RMLer: Synthesizing Novel Objects across Diverse Categories via Reinforcement Mixing Learning

Novel object synthesis by integrating distinct textual concepts from diverse categories remains a significant challenge in Text-to-Image (T2I) generation. Existing methods often suffer from insufficient concept mixing, lack of rigorous evaluation, and suboptimal outputs-manifesting as conceptual imbalance, superficial combinations, or mere juxtapositions. To address these limitations, we propose Reinforcement Mixing Learning (RMLer), a framework that formulates cross-category concept fusion as a reinforcement learning problem: mixed features serve as states, mixing strategies as actions, and visual outcomes as rewards. Specifically, we design an MLP-policy network to predict dynamic coefficients for blending cross-category text embeddings. We further introduce visual rewards based on (1) semantic similarity and (2) compositional balance between the fused object and its constituent concepts, optimizing the policy via proximal policy optimization. At inference, a selection strategy leverages these rewards to curate the highest-quality fused objects. Extensive experiments demonstrate RMLer's superiority in synthesizing coherent, high-fidelity objects from diverse categories, outperforming existing methods. Our work provides a robust framework for generating novel visual concepts, with promising applications in film, gaming, and design.

Multi-Joint Physics-Informed Deep Learning Framework for Time-Efficient Inverse Dynamics

Time-efficient estimation of muscle activations and forces across multi-joint systems is critical for clinical assessment and assistive device control. However, conventional approaches are computationally expensive and lack a high-quality labeled dataset for multi-joint applications. To address these challenges, we propose a physics-informed deep learning framework that estimates muscle activations and forces directly from kinematics. The framework employs a novel Multi-Joint Cross-Attention (MJCA) module with Bidirectional Gated Recurrent Unit (BiGRU) layers to capture inter-joint coordination, enabling each joint to adaptively integrate motion information from others. By embedding multi-joint dynamics, inter-joint coupling, and external force interactions into the loss function, our Physics-Informed MJCA-BiGRU (PI-MJCA-BiGRU) delivers physiologically consistent predictions without labeled data while enabling time-efficient inference. Experimental validation on two datasets demonstrates that PI-MJCA-BiGRU achieves performance comparable to conventional supervised methods without requiring ground-truth labels, while the MJCA module significantly enhances inter-joint coordination modeling compared to other baseline architectures.

LoPT: Lossless Parallel Tokenization Acceleration for Long Context Inference of Large Language Model

Long context inference scenarios have become increasingly important for large language models, yet they introduce significant computational latency. While prior research has optimized long-sequence inference through operators, model architectures, and system frameworks, tokenization remains an overlooked bottleneck. Existing parallel tokenization methods accelerate processing through text segmentation and multi-process tokenization, but they suffer from inconsistent results due to boundary artifacts that occur after merging. To address this, we propose LoPT, a novel Lossless Parallel Tokenization framework that ensures output identical to standard sequential tokenization. Our approach employs character-position-based matching and dynamic chunk length adjustment to align and merge tokenized segments accurately. Extensive experiments across diverse long-text datasets demonstrate that LoPT achieves significant speedup while guaranteeing lossless tokenization. We also provide theoretical proof of consistency and comprehensive analytical studies to validate the robustness of our method.

Deep learning models are vulnerable, but adversarial examples are even more vulnerable

Understanding intrinsic differences between adversarial examples and clean samples is key to enhancing DNN robustness and detection against adversarial attacks. This study first empirically finds that image-based adversarial examples are notably sensitive to occlusion. Controlled experiments on CIFAR-10 used nine canonical attacks (e.g., FGSM, PGD) to generate adversarial examples, paired with original samples for evaluation. We introduce Sliding Mask Confidence Entropy (SMCE) to quantify model confidence fluctuation under occlusion. Using 1800+ test images, SMCE calculations supported by Mask Entropy Field Maps and statistical distributions show adversarial examples have significantly higher confidence volatility under occlusion than originals. Based on this, we propose Sliding Window Mask-based Adversarial Example Detection (SWM-AED), which avoids catastrophic overfitting of conventional adversarial training. Evaluations across classifiers and attacks on CIFAR-10 demonstrate robust performance, with accuracy over 62% in most cases and up to 96.5%.

Learning to reason about rare diseases through retrieval-augmented agents

Rare diseases represent the long tail of medical imaging, where AI models often fail due to the scarcity of representative training data. In clinical workflows, radiologists frequently consult case reports and literature when confronted with unfamiliar findings. Following this line of reasoning, we introduce RADAR, Retrieval Augmented Diagnostic Reasoning Agents, an agentic system for rare disease detection in brain MRI. Our approach uses AI agents with access to external medical knowledge by embedding both case reports and literature using sentence transformers and indexing them with FAISS to enable efficient similarity search. The agent retrieves clinically relevant evidence to guide diagnostic decision making on unseen diseases, without the need of additional training. Designed as a model-agnostic reasoning module, RADAR can be seamlessly integrated with diverse large language models, consistently improving their rare pathology recognition and interpretability. On the NOVA dataset comprising 280 distinct rare diseases, RADAR achieves up to a 10.2% performance gain, with the strongest improvements observed for open source models such as DeepSeek. Beyond accuracy, the retrieved examples provide interpretable, literature grounded explanations, highlighting retrieval-augmented reasoning as a powerful paradigm for low-prevalence conditions in medical imaging.

AnyECG-Lab: An Exploration Study of Fine-tuning an ECG Foundation Model to Estimate Laboratory Values from Single-Lead ECG Signals

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal, offers a promising modality for rapid laboratory estimation. Recent progress in deep learning has enabled the extraction of latent hematological signatures from ECGs. However, existing models are constrained by low signal-to-noise ratios, substantial inter-individual variability, limited data diversity, and suboptimal generalization, especially when adapted to low-lead wearable devices. In this work, we conduct an exploratory study leveraging transfer learning to fine-tune ECGFounder, a large-scale pre-trained ECG foundation model, on the Multimodal Clinical Monitoring in the Emergency Department (MC-MED) dataset from Stanford. We generated a corpus of more than 20 million standardized ten-second ECG segments to enhance sensitivity to subtle biochemical correlates. On internal validation, the model demonstrated strong predictive performance (area under the curve above 0.65) for thirty-three laboratory indicators, moderate performance (between 0.55 and 0.65) for fifty-nine indicators, and limited performance (below 0.55) for sixteen indicators. This study provides an efficient artificial-intelligence driven solution and establishes the feasibility scope for real-time, non-invasive estimation of laboratory values.

Suicidal Comment Tree Dataset: Enhancing Risk Assessment and Prediction Through Contextual Analysis

Suicide remains a critical global public health issue. While previous studies have provided valuable insights into detecting suicidal expressions in individual social media posts, limited attention has been paid to the analysis of longitudinal, sequential comment trees for predicting a user's evolving suicidal risk. Users, however, often reveal their intentions through historical posts and interactive comments over time. This study addresses this gap by investigating how the information in comment trees affects both the discrimination and prediction of users' suicidal risk levels. We constructed a high-quality annotated dataset, sourced from Reddit, which incorporates users' posting history and comments, using a refined four-label annotation framework based on the Columbia Suicide Severity Rating Scale (C-SSRS). Statistical analysis of the dataset, along with experimental results from Large Language Models (LLMs) experiments, demonstrates that incorporating comment trees data significantly enhances the discrimination and prediction of user suicidal risk levels. This research offers a novel insight to enhancing the detection accuracy of at-risk individuals, thereby providing a valuable foundation for early suicide intervention strategies.

Hierarchical Federated Learning for Social Network with Mobility

Federated Learning (FL) offers a decentralized solution that allows collaborative local model training and global aggregation, thereby protecting data privacy. In conventional FL frameworks, data privacy is typically preserved under the assumption that local data remains absolutely private, whereas the mobility of clients is frequently neglected in explicit modeling. In this paper, we propose a hierarchical federated learning framework based on the social network with mobility namely HFL-SNM that considers both data sharing among clients and their mobility patterns. Under the constraints of limited resources, we formulate a joint optimization problem of resource allocation and client scheduling, which objective is to minimize the energy consumption of clients during the FL process. In social network, we introduce the concepts of Effective Data Coverage Rate and Redundant Data Coverage Rate. We analyze the impact of effective data and redundant data on the model performance through preliminary experiments. We decouple the optimization problem into multiple sub-problems, analyze them based on preliminary experimental results, and propose Dynamic Optimization in Social Network with Mobility (DO-SNM) algorithm. Experimental results demonstrate that our algorithm achieves superior model performance while significantly reducing energy consumption, compared to traditional baseline algorithms.

IRDFusion: Iterative Relation-Map Difference guided Feature Fusion for Multispectral Object Detection

Current multispectral object detection methods often retain extraneous background or noise during feature fusion, limiting perceptual performance.To address this, we propose an innovative feature fusion framework based on cross-modal feature contrastive and screening strategy, diverging from conventional approaches. The proposed method adaptively enhances salient structures by fusing object-aware complementary cross-modal features while suppressing shared background interference.Our solution centers on two novel, specially designed modules: the Mutual Feature Refinement Module (MFRM) and the Differential Feature Feedback Module (DFFM). The MFRM enhances intra- and inter-modal feature representations by modeling their relationships, thereby improving cross-modal alignment and discriminative power.Inspired by feedback differential amplifiers, the DFFM dynamically computes inter-modal differential features as guidance signals and feeds them back to the MFRM, enabling adaptive fusion of complementary information while suppressing common-mode noise across modalities. To enable robust feature learning, the MFRM and DFFM are integrated into a unified framework, which is formally formulated as an Iterative Relation-Map Differential Guided Feature Fusion mechanism, termed IRDFusion. IRDFusion enables high-quality cross-modal fusion by progressively amplifying salient relational signals through iterative feedback, while suppressing feature noise, leading to significant performance gains.In extensive experiments on FLIR, LLVIP and M$^3$FD datasets, IRDFusion achieves state-of-the-art performance and consistently outperforms existing methods across diverse challenging scenarios, demonstrating its robustness and effectiveness. Code will be available at https://github.com/61s61min/IRDFusion.git.