Holter-to-Sleep: AI-Enabled Repurposing of Single-Lead ECG for Sleep Phenotyping

Sleep disturbances are tightly linked to cardiovascular risk, yet polysomnography (PSG)-the clinical reference standard-remains resource-intensive and poorly suited for multi-night, home-based, and large-scale screening. Single-lead electrocardiography (ECG), already ubiquitous in Holter and patch-based devices, enables comfortable long-term acquisition and encodes sleep-relevant physiology through autonomic modulation and cardiorespiratory coupling. Here, we present a proof-of-concept Holter-to-Sleep framework that, using single-lead ECG as the sole input, jointly supports overnight sleep phenotyping and Holter-grade cardiac phenotyping within the same recording, and further provides an explicit analytic pathway for scalable cardio-sleep association studies. The framework is developed and validated on a pooled multi-center PSG sample of 10,439 studies spanning four public cohorts, with independent external evaluation to assess cross-cohort generalizability, and additional real-world feasibility assessment using overnight patch-ECG recordings via objective-subjective consistency analysis. This integrated design enables robust extraction of clinically meaningful overnight sleep phenotypes under heterogeneous populations and acquisition conditions, and facilitates systematic linkage between ECG-derived sleep metrics and arrhythmia-related Holter phenotypes. Collectively, the Holter-to-Sleep paradigm offers a practical foundation for low-burden, home-deployable, and scalable cardio-sleep monitoring and research beyond traditional PSG-centric workflows.

DAIT: Distillation from Vision-Language Models to Lightweight Classifiers with Adaptive Intermediate Teacher Transfer

Large-scale Vision-Language Models (VLMs) encode rich multimodal semantics that are highly beneficial for fine-grained visual categorization (FGVC). However, their prohibitive computational cost hinders practical deployment in resource-constrained environments. Although knowledge distillation contributes to transferring VLMs capacity to lightweight classifiers, conventional distillation mechanisms, which directly transfer from a generic VLM to a compact student, often yield suboptimal results due to severe architectural misalignment and introducing task-irrelevant information. To alleviate this limitation, we propose Distillation with Adaptive Intermediate Teacher transfer (DAIT) in this study, facilitating adaptive knowledge transfer from VLMs to lightweight students. DAIT introduces a trainable intermediate teacher that learns to transfer frozen VLMs representations under explicit supervision from the target fine-grained task. This intermediate teacher adaptively enhances discriminative visual cues, thereby producing compact and task-aligned knowledge that can be reliably distilled into lightweight models. Extensive evaluations on multiple FGVC benchmarks with diverse student architectures demonstrate that our method achieves respective performance gains of 12.63% and 8.34% on FGVC-Aircraft and CUB-200-2011 datasets, establishing DAIT as a principled paradigm for transferring from general-purpose VLMS to deployable fine-grained recognition models.

An Industrial-Scale Insurance LLM Achieving Verifiable Domain Mastery and Hallucination Control without Competence Trade-offs

Adapting Large Language Models (LLMs) to high-stakes vertical domains like insurance presents a significant challenge: scenarios demand strict adherence to complex regulations and business logic with zero tolerance for hallucinations. Existing approaches often suffer from a Competency Trade-off - sacrificing general intelligence for domain expertise - or rely heavily on RAG without intrinsic reasoning. To bridge this gap, we present INS-S1, an insurance-specific LLM family trained via a novel end-to-end alignment paradigm. Our approach features two methodological innovations: (1) A Verifiable Data Synthesis System that constructs hierarchical datasets for actuarial reasoning and compliance; and (2) A Progressive SFT-RL Curriculum Framework that integrates dynamic data annealing with a synergistic mix of Verified Reasoning (RLVR) and AI Feedback (RLAIF). By optimizing data ratios and reward signals, this framework enforces domain constraints while preventing catastrophic forgetting. Additionally, we release INSEva, the most comprehensive insurance benchmark to date (39k+ samples). Extensive experiments show that INS-S1 achieves SOTA performance on domain tasks, significantly outperforming DeepSeek-R1 and Gemini-2.5-Pro. Crucially, it maintains top-tier general capabilities and achieves a record-low 0.6% hallucination rate (HHEM). Our results demonstrate that rigorous domain specialization can be achieved without compromising general intelligence.

ImagiNav: Scalable Embodied Navigation via Generative Visual Prediction and Inverse Dynamics

Enabling robots to navigate open-world environments via natural language is critical for general-purpose autonomy. Yet, Vision-Language Navigation has relied on end-to-end policies trained on expensive, embodiment-specific robot data. While recent foundation models trained on vast simulation data show promise, the challenge of scaling and generalizing due to the limited scene diversity and visual fidelity in simulation persists. To address this gap, we propose ImagiNav, a novel modular paradigm that decouples visual planning from robot actuation, enabling the direct utilization of diverse in-the-wild navigation videos. Our framework operates as a hierarchy: a Vision-Language Model first decomposes instructions into textual subgoals; a finetuned generative video model then imagines the future video trajectory towards that subgoal; finally, an inverse dynamics model extracts the trajectory from the imagined video, which can then be tracked via a low-level controller. We additionally develop a scalable data pipeline of in-the-wild navigation videos auto-labeled via inverse dynamics and a pretrained Vision-Language Model. ImagiNav demonstrates strong zero-shot transfer to robot navigation without requiring robot demonstrations, paving the way for generalist robots that learn navigation directly from unlabeled, open-world data.

Antenna Placement Design for Interference Exploitation in Pinching-Antenna Systems

Pinching-antenna systems (PASs) have been proposed as a flexible antenna technology to fulfill the stringent requirements of high data rate and large-scale equipment deployment in future wireless networks. The principle of PA involves mapping a signal over dielectric waveguides for transmission. By adjusting the positions of pinching antennas (PAs) over the waveguides, with the aim of gain enhancement for line-of-sight links and the reduction of large-scale path loss. Symbol-level precoding (SLP) is a nonlinear precoding technique, which converts multi-user interference into constructive interference via beamforming design at symbol level. In this paper, we study the combination of SLP and PAS, leveraging the advantages of PAS to further enhance the ability of SLP to convert constructive interference. The transmit power minimization problem is formulated and solved for the multiple waveguides multiple PAs system by jointly beamforming and PAs' positions design under the SLP principle. The alternating optimization (AO) framework is applied to decouple the beamforming vector and the position coefficient of PA. For the given beamforming vectors, a new objective function is formulated with respect to the positions of the PAs. With the characteristics of the formulated objective function, the optimization problem for the position coefficients of PAs can be decomposed into multiple independent subproblems, each corresponding to a PA's position coefficient, and a projected gradient descent (PGD)-based method, constrained by the feasible movable region of each PA, is then developed to obtain the suboptimal position coefficients. The performance improvements achieved by the combination of PAS and SLP, as well as the effectiveness of the proposed algorithm are verified through the simulation results.

MV-SAM3D: Adaptive Multi-View Fusion for Layout-Aware 3D Generation

Recent unified 3D generation models have made remarkable progress in producing high-quality 3D assets from a single image. Notably, layout-aware approaches such as SAM3D can reconstruct multiple objects while preserving their spatial arrangement, opening the door to practical scene-level 3D generation. However, current methods are limited to single-view input and cannot leverage complementary multi-view observations, while independently estimated object poses often lead to physically implausible layouts such as interpenetration and floating artifacts. We present MV-SAM3D, a training-free framework that extends layout-aware 3D generation with multi-view consistency and physical plausibility. We formulate multi-view fusion as a Multi-Diffusion process in 3D latent space and propose two adaptive weighting strategies -- attention-entropy weighting and visibility weighting -- that enable confidence-aware fusion, ensuring each viewpoint contributes according to its local observation reliability. For multi-object composition, we introduce physics-aware optimization that injects collision and contact constraints both during and after generation, yielding physically plausible object arrangements. Experiments on standard benchmarks and real-world multi-object scenes demonstrate significant improvements in reconstruction fidelity and layout plausibility, all without any additional training. Code is available at https://github.com/devinli123/MV-SAM3D.

Multi-Agent Causal Reasoning for Suicide Ideation Detection Through Online Conversations

Suicide remains a pressing global public health concern. While social media platforms offer opportunities for early risk detection through online conversation trees, existing approaches face two major limitations: (1) They rely on predefined rules (e.g., quotes or relies) to log conversations that capture only a narrow spectrum of user interactions, and (2) They overlook hidden influences such as user conformity and suicide copycat behavior, which can significantly affect suicidal expression and propagation in online communities. To address these limitations, we propose a Multi-Agent Causal Reasoning (MACR) framework that collaboratively employs a Reasoning Agent to scale user interactions and a Bias-aware Decision-Making Agent to mitigate harmful biases arising from hidden influences. The Reasoning Agent integrates cognitive appraisal theory to generate counterfactual user reactions to posts, thereby scaling user interactions. It analyses these reactions through structured dimensions, i.e., cognitive, emotional, and behavioral patterns, with a dedicated sub-agent responsible for each dimension. The Bias-aware Decision-Making Agent mitigates hidden biases through a front-door adjustment strategy, leveraging the counterfactual user reactions produced by the Reasoning Agent. Through the collaboration of reasoning and bias-aware decision making, the proposed MACR framework not only alleviates hidden biases, but also enriches contextual information of user interactions with counterfactual knowledge. Extensive experiments on real-world conversational datasets demonstrate the effectiveness and robustness of MACR in identifying suicide risk.

An Empirical Analysis of Cooperative Perception for Occlusion Risk Mitigation

Occlusions present a significant challenge for connected and automated vehicles, as they can obscure critical road users from perception systems. Traditional risk metrics often fail to capture the cumulative nature of these threats over time adequately. In this paper, we propose a novel and universal risk assessment metric, the Risk of Tracking Loss (RTL), which aggregates instantaneous risk intensity throughout occluded periods. This provides a holistic risk profile that encompasses both high-intensity, short-term threats and prolonged exposure. Utilizing diverse and high-fidelity real-world datasets, a large-scale statistical analysis is conducted to characterize occlusion risk and validate the effectiveness of the proposed metric. The metric is applied to evaluate different vehicle-to-everything (V2X) deployment strategies. Our study shows that full V2X penetration theoretically eliminates this risk, the reduction is highly nonlinear; a substantial statistical benefit requires a high penetration threshold of 75-90%. To overcome this limitation, we propose a novel asymmetric communication framework that allows even non-connected vehicles to receive warnings. Experimental results demonstrate that this paradigm achieves better risk mitigation performance. We found that our approach at 25% penetration outperforms the traditional symmetric model at 75%, and benefits saturate at only 50% penetration. This work provides a crucial risk assessment metric and a cost-effective, strategic roadmap for accelerating the safety benefits of V2X deployment.

OMGs: A multi-agent system supporting MDT decision-making across the ovarian tumour care continuum

Ovarian tumour management has increasingly relied on multidisciplinary tumour board (MDT) deliberation to address treatment complexity and disease heterogeneity. However, most patients worldwide lack access to timely expert consensus, particularly in resource-constrained centres where MDT resources are scarce or unavailable. Here we present OMGs (Ovarian tumour Multidisciplinary intelligent aGent System), a multi-agent AI framework where domain-specific agents deliberate collaboratively to integrate multidisciplinary evidence and generate MDT-style recommendations with transparent rationales. To systematically evaluate MDT recommendation quality, we developed SPEAR (Safety, Personalization, Evidence, Actionability, Robustness) and validated OMGs across diverse clinical scenarios spanning the care continuum. In multicentre re-evaluation, OMGs achieved performance comparable to expert MDT consensus ($4.45 \pm 0.30$ versus $4.53 \pm 0.23$), with higher Evidence scores (4.57 versus 3.92). In prospective multicentre evaluation (59 patients), OMGs demonstrated high concordance with routine MDT decisions. Critically, in paired human-AI studies, OMGs most substantially enhanced clinicians' recommendations in Evidence and Robustness, the dimensions most compromised when multidisciplinary expertise is unavailable. These findings suggest that multi-agent deliberative systems can achieve performance comparable to expert MDT consensus, with potential to expand access to specialized oncology expertise in resource-limited settings.

SPLIT: Sparse Incremental Learning of Error Dynamics for Control-Oriented Modeling in Autonomous Vehicles

Accurate, computationally efficient, and adaptive vehicle models are essential for autonomous vehicle control. Hybrid models that combine a nominal model with a Gaussian Process (GP)-based residual model have emerged as a promising approach. However, the GP-based residual model suffers from the curse of dimensionality, high evaluation complexity, and the inefficiency of online learning, which impede the deployment in real-time vehicle controllers. To address these challenges, we propose SPLIT, a sparse incremental learning framework for control-oriented vehicle dynamics modeling. SPLIT integrates three key innovations: (i) Model Decomposition. We decompose the vehicle model into invariant elements calibrated by experiments, and variant elements compensated by the residual model to reduce feature dimensionality. (ii) Local Incremental Learning. We define the valid region in the feature space and partition it into subregions, enabling efficient online learning from streaming data. (iii) GP Sparsification. We use bayesian committee machine to ensure scalable online evaluation. Integrated into model-based controllers, SPLIT is evaluated in aggressive simulations and real-vehicle experiments. Results demonstrate that SPLIT improves model accuracy and control performance online. Moreover, it enables rapid adaptation to vehicle dynamics deviations and exhibits robust generalization to previously unseen scenarios.