TOPCELL: Topology Optimization of Standard Cell via LLMs

Transistor topology optimization is a critical step in standard cell design, directly dictating diffusion sharing efficiency and downstream routability. However, identifying optimal topologies remains a persistent bottleneck, as conventional exhaustive search methods become computationally intractable with increasing circuit complexity in advanced nodes. This paper introduces TOPCELL, a novel and scalable framework that reformulates high-dimensional topology exploration as a generative task using Large Language Models (LLMs). We employ Group Relative Policy Optimization (GRPO) to fine-tune the model, aligning its topology optimization strategy with logical (circuit) and spatial (layout) constraints. Experimental results within an industrial flow targeting an advanced 2nm technology node demonstrate that TOPCELL significantly outperforms foundation models in discovering routable, physically-aware topologies. When integrated into a state-of-the-art (SOTA) automation flow for a 7nm library generation task, TOPCELL exhibits robust zero-shot generalization and matches the layout quality of exhaustive solvers while achieving an 85.91x speedup.

FoodSense: A Multisensory Food Dataset and Benchmark for Predicting Taste, Smell, Texture, and Sound from Images

Humans routinely infer taste, smell, texture, and even sound from food images a phenomenon well studied in cognitive science. However, prior vision language research on food has focused primarily on recognition tasks such as meal identification, ingredient detection, and nutrition estimation. Image-based prediction of multisensory experience remains largely unexplored. We introduce FoodSense, a human-annotated dataset for cross-sensory inference containing 66,842 participant-image pairs across 2,987 unique food images. Each pair includes numeric ratings (1-5) and free-text descriptors for four sensory dimensions: taste, smell, texture, and sound. To enable models to both predict and explain sensory expectations, we expand short human annotations into image-grounded reasoning traces. A large language model generates visual justifications conditioned on the image, ratings, and descriptors. Using these annotations, we train FoodSense-VL, a vision language benchmark model to produce both multisensory ratings and grounded explanations directly from food images. This work connects cognitive science findings on cross-sensory perception with modern instruction tuning for multimodal models and shows that many popular evaluation metrics are insufficient for visually sensory inference.

Text-Attributed Knowledge Graph Enrichment with Large Language Models for Medical Concept Representation

In electronic health record (EHR) mining, learning high-quality representations of medical concepts (e.g., standardized diagnosis, medication, and procedure codes) is fundamental for downstream clinical prediction. However, robust concept representation learning is hindered by two key challenges: (i) clinically important cross-type dependencies (e.g., diagnosis-medication and medication-procedure relations) are often missing or incomplete in existing ontology resources, limiting the ability to model complex EHR patterns; and (ii) rich clinical semantics are often missing from structured resources, and even when available as text, are difficult to integrate with KG structure for representation learning. To address these challenges, we present CoMed, an LLM-empowered graph learning framework for medical concept representation. CoMed first builds a global knowledge graph (KG) over medical codes by combining statistically reliable associations mined from EHRs with type-constrained LLM prompting to infer semantic relations. It then utilizes LLMs to enrich the KG into a text-attributed graph by generating node descriptions and edge rationales, providing semantic signals for both concepts and their relationships. Finally, CoMed jointly trains a LoRA-tuned LLaMA text encoder with a heterogeneous GNN, fusing text semantics and graph structure into unified concept embeddings. Extensive experiments on MIMIC-III and MIMIC-IV show that CoMed consistently improves prediction performance and serves as an effective plug-in concept encoder for standard EHR pipelines.

Fall Risk and Gait Analysis in Community-Dwelling Older Adults using World-Spaced 3D Human Mesh Recovery

Gait assessment is a key clinical indicator of fall risk and overall health in older adults. However, standard clinical practice is largely limited to stopwatch-measured gait speed. We present a pipeline that leverages a 3D Human Mesh Recovery (HMR) model to extract gait parameters from recordings of older adults completing the Timed Up and Go (TUG) test. From videos recorded across different community centers, we extract and analyze spatiotemporal gait parameters, including step time, sit-to-stand duration, and step length. We found that video-derived step time was significantly correlated with IMU-based insole measurements. Using linear mixed effects models, we confirmed that shorter, more variable step lengths and longer sit-to-stand durations were predicted by higher self-rated fall risk and fear of falling. These findings demonstrate that our pipeline can enable accessible and ecologically valid gait analysis in community settings.

LiveGesture Streamable Co-Speech Gesture Generation Model

We propose LiveGesture, the first fully streamable, speech-driven full-body gesture generation framework that operates with zero look-ahead and supports arbitrary sequence length. Unlike existing co-speech gesture methods, which are designed for offline generation and either treat body regions independently or entangle all joints within a single model, LiveGesture is built from the ground up for causal, region-coordinated motion generation. LiveGesture consists of two main modules: the Streamable Vector Quantized Motion Tokenizer (SVQ) and the Hierarchical Autoregressive Transformer (HAR). The SVQ tokenizer converts the motion sequence of each body region into causal, discrete motion tokens, enabling real-time, streamable token decoding. On top of SVQ, HAR employs region-expert autoregressive (xAR) transformers to model expressive, fine-grained motion dynamics for each body region. A causal spatio-temporal fusion module (xAR Fusion) then captures and integrates correlated motion dynamics across regions. Both xAR and xAR Fusion are conditioned on live, continuously arriving audio signals encoded by a streamable causal audio encoder. To enhance robustness under streaming noise and prediction errors, we introduce autoregressive masking training, which leverages uncertainty-guided token masking and random region masking to expose the model to imperfect, partially erroneous histories during training. Experiments on the BEAT2 dataset demonstrate that LiveGesture produces coherent, diverse, and beat-synchronous full-body gestures in real time, matching or surpassing state-of-the-art offline methods under true zero look-ahead conditions.

Data-Efficient Surgical Phase Segmentation in Small-Incision Cataract Surgery: A Controlled Study of Vision Foundation Models

Surgical phase segmentation is central to computer-assisted surgery, yet robust models remain difficult to develop when labeled surgical videos are scarce. We study data-efficient phase segmentation for manual small-incision cataract surgery (SICS) through a controlled comparison of visual representations. To isolate representation quality, we pair each visual encoder with the same temporal model (MS-TCN++) under identical training and evaluation settings on SICS-155 (19 phases). We compare supervised encoders (ResNet-50, I3D) against large self-supervised foundation models (DINOv3, V-JEPA2), and use a cached-feature pipeline that decouples expensive visual encoding from lightweight temporal learning. Foundation-model features improve segmentation performance in this setup, with DINOv3 ViT-7B achieving the best overall results (83.4% accuracy, 87.0 edit score). We further examine cataract-domain transfer using unlabeled videos and lightweight adaptation, and analyze when it helps or hurts. Overall, the study indicates strong transferability of modern vision foundation models to surgical workflow understanding and provides practical guidance for low-label medical video settings. The project website is available at: https://sl2005.github.io/DataEfficient-sics-phase-seg/

Turning Generators into Retrievers: Unlocking MLLMs for Natural Language-Guided Geo-Localization

Natural-language Guided Cross-view Geo-localization (NGCG) aims to retrieve geo-tagged satellite imagery using textual descriptions of ground scenes. While recent NGCG methods commonly rely on CLIP-style dual-encoder architectures, they often suffer from weak cross-modal generalization and require complex architectural designs. In contrast, Multimodal Large Language Models (MLLMs) offer powerful semantic reasoning capabilities but are not directly optimized for retrieval tasks. In this work, we present a simple yet effective framework to adapt MLLMs for NGCG via parameter-efficient finetuning. Our approach optimizes latent representations within the MLLM while preserving its pretrained multimodal knowledge, enabling strong cross-modal alignment without redesigning model architectures. Through systematic analysis of diverse variables, from model backbone to feature aggregation, we provide practical and generalizable insights for leveraging MLLMs in NGCG. Our method achieves SOTA on GeoText-1652 with a 12.2% improvement in Text-to-Image Recall@1 and secures top performance in 5 out of 12 subtasks on CVG-Text, all while surpassing baselines with far fewer trainable parameters. These results position MLLMs as a robust foundation for semantic cross-view retrieval and pave the way for MLLM-based NGCG to be adopted as a scalable, powerful alternative to traditional dual-encoder designs. Project page and code are available at https://yuqichen888.github.io/NGCG-MLLMs-web/.

Differentiable free energy surface: a variational approach to directly observing rare events using generative deep-learning models

Rare events are central to the evolution of complex many-body systems, characterized as key transitional configurations on the free energy surface (FES). Conventional methods require adequate sampling of rare event transitions to obtain the FES, which is computationally very demanding. Here we introduce the variational free energy surface (VaFES), a dataset-free framework that directly models FESs using tractable-density generative models. Rare events can then be immediately identified from the FES with their configurations generated directly via one-shot sampling of generative models. By extending a coarse-grained collective variable (CV) into its reversible equivalent, VaFES constructs a latent space of intermediate representation in which the CVs explicitly occupy a subset of dimensions. This latent-space construction preserves the physical interpretability and transparent controllability of the CVs by design, while accommodating arbitrary CV formulations. The reversibility makes the system energy exactly accessible, enabling variational optimization of the FES without pre-generated simulation data. A single optimization yields a continuous, differentiable FES together with one-shot generation of rare-event configurations. Our method can reproduce the exact analytical solution for the bistable dimer potential and identify a chignolin native folded state in close alignment with the experimental NMR structure. Our approach thus establishes a scalable, systematic framework for advancing the study of complex statistical systems.

How Should Video LLMs Output Time? An Analysis of Efficient Temporal Grounding Paradigms

While Multimodal Large Language Models (MLLMs) have advanced Video Temporal Grounding (VTG), existing methods often couple output paradigms with different backbones, datasets, and training protocols. This makes it challenging to isolate the specific impact of the output design. Additionally, as VTG systems are increasingly considered for resource-constrained edge deployment, the trade-off between output formulation and system-level efficiency requires systematic investigation. In this paper, we present a controlled empirical study comparing three dominant VTG output paradigms: Text Numeral Generation, Temporal Token Generation, and Continuous Temporal Decoding. We evaluate these paradigms across identical compact VLMs (SmolVLM2, FastVLM, and Molmo2) using consistent datasets and LoRA fine-tuning protocols. Evaluations on Charades-STA, QVHighlights, and YouCook2 measure both localization accuracy and system efficiency, including inference latency, training throughput, and parameter overhead. Our results demonstrate that the choice of output formulation significantly affects both grounding accuracy and computational cost, independent of model scale. Specifically, the continuous distribution paradigm consistently achieves the most favorable efficiency-accuracy trade-off on the Pareto frontier, delivering robust localization with minimal latency overhead. These findings provide objective empirical guidelines for designing efficient, deployment-ready VTG systems.

Mechanistic Circuit-Based Knowledge Editing in Large Language Models

Deploying Large Language Models (LLMs) in real-world dynamic environments raises the challenge of updating their pre-trained knowledge. While existing knowledge editing methods can reliably patch isolated facts, they frequently suffer from a "Reasoning Gap", where the model recalls the edited fact but fails to utilize it in multi-step reasoning chains. To bridge this gap, we introduce MCircKE (\underline{M}echanistic \underline{Circ}uit-based \underline{K}nowledge \underline{E}diting), a novel framework that enables a precise "map-and-adapt" editing procedure. MCircKE first identifies the causal circuits responsible for a specific reasoning task, capturing both the storage of the fact and the routing of its logical consequences. It then surgically update parameters exclusively within this mapped circuit. Extensive experiments on the MQuAKE-3K benchmark demonstrate the effectiveness of the proposed method for multi-hop reasoning in knowledge editing.