Image-to-image translation is the process of converting an image from one domain to another using deep learning techniques.
Federated graph learning (FGL) enables collaborative training on graph data across multiple clients. As graph data increasingly contain multimodal node attributes such as text and images, multimodal federated graph learning (MM-FGL) has become an important yet substantially harder setting. The key challenge is that clients from different modality domains may not share a common semantic space: even for the same concept, their local encoders can produce inconsistent representations before collaboration begins. This makes direct parameter coordination unreliable and further causes two downstream problems: forcing heterogeneous client representations into a naively shared semantic space may create false semantic agreement, and graph message passing may amplify residual inconsistency across neighborhoods. To address this issue, we propose \textbf{STAGE}, a protocol-first framework for MM-FGL. Instead of relying on direct parameter averaging, STAGE builds a shared semantic space that first translates heterogeneous multimodal features into comparable representations and then regulates how these representations propagate over local graph structures. In this way, STAGE not only improves cross-client semantic calibration, but also reduces the risk of inconsistency amplification during graph learning. Extensive experiments on 8 multimodal-attributed graphs across 5 graph-centric and modality-centric tasks show that STAGE consistently achieves state-of-the-art performance while reducing per-round communication payload.
Optical Chemical Structure Recognition (OCSR) aims to translate molecular diagrams in scientific literature into machine-readable formats, but current systems remain unreliable on real-world images due to substantial visual and chemical complexity. We introduce MOSAIC, a dual-dimensional difficulty framework with 37 fine-grained labels that jointly characterize visual interference and chemical semantic challenges in molecular diagrams. Based on this framework, we construct MolRecBench-Wild, a benchmark of 5,029 structures from 820 recent chemistry papers, covering the full difficulty spectrum observed in real publications. To enable faithful semantic evaluation beyond SMILES and MolFile, we propose CARBON, a representation language capable of expressing valence variations, icon-based groups, and other non-standard chemical semantics. We further adopt a dual-track evaluation protocol supporting both CARBON and SMILES outputs for broad model compatibility. Comprehensive experiments over 18 OCSR-capable models reveal severe performance degradation on MolRecBench-Wild, exposing a large gap between previous patent benchmarks and real-world academic scenarios.
Deep generative models provide flexible frameworks for modeling complex, structured data such as images, videos, 3D objects, and texts. However, when applied to sequences of human skeletons, standard variational autoencoders (VAEs) often allocate substantial capacity to nuisance factors-such as camera orientation, subject scale, viewpoint, and execution speed-rather than the intrinsic geometry of shapes and their motion. We propose the Elastic Shape - Variational Autoencoder (ES-VAE), a geometry-aware generative model for skeletal trajectories that leverages the transported square-root velocity field (TSRVF) representation on Kendall's shape manifold. This representation inherently removes rigid translations, rotations, and global scaling of shapes, and temporal rate variability of sequences, isolating the underlying shape dynamics. The ES-VAE encoder maps skeletal sequences to a low-dimensional latent space incorporating the Riemannian logarithm map, while the decoder reconstructs sequences using the corresponding exponential map. We demonstrate the effectiveness of ES-VAE on two datasets. First, we analyze skeletal gait cycles to predict clinical mobility scores and classify subjects into healthy and post-stroke groups. Second, we evaluate action recognition on the NTU RGB+D dataset. Across both settings, ES-VAE consistently outperforms standard VAEs and a range of sequence modeling baselines, including temporal convolutional networks, transformers, and graph convolutional networks. More broadly, ES-VAE provides a principled framework for learning generative models of longitudinal data on pose shape manifolds, offering improved latent representation and downstream performance compared to existing deep learning approaches.
Chart-to-table translation converts chart images into structured tabular data. Accurate translation is crucial for Multimodal Language Model (MLM) to answer complex queries. We observe imbalances in the number of images across different aspects of the y-axis information in public chart datasets. Such imbalances can introduce unintended biases, causing uneven MLM performance. Previous works have not systematically examined these biases. To address this gap, we propose a new framework, FairChart2Table, for analyzing y-axis-related bias on five state-of-the-art models. Key Findings: (1) There are significant y-axis biases related to the digit length of the major tick values, the number of major ticks, the range of values, and the tick value format (e.g., abbreviation or scientific format). (2) The number of legends/entities in chart images impacts MLM performance. (3) Prompting MLM with y-axis information can significantly enhance the performance for some MLMs.
Robust in-bed human pose estimation under blanket occlusion remains challenging due to the scarcity of reliable labeled training data for heavily covered poses. Existing approaches rely on multi-modal sensing or image-to-image translation frameworks that remain conditioned on visible source imagery, limiting scalability and pose diversity. In this work, we reformulate occlusion-aware augmentation as a geometry-conditioned generative modeling task. We conduct a systematic comparison of deterministic masking, unpaired translation, paired diffusion-based translation, and a proposed pose-conditioned Latent Diffusion Model (Pose-LDM). Unlike image-guided methods, Pose-LDM synthesizes blanket-covered images directly from skeletal keypoints, eliminating dependence on paired supervision and pixel-level source-image conditioning while enabling generation from arbitrary pose inputs. All augmentation strategies are evaluated through their impact on downstream pose estimation under a fixed backbone. Pose- LDM achieves the highest strict localization accuracy under severe occlusion while maintaining overall detection performance comparable to paired diffusion models, approaching the performance of fully supervised training. These results demonstrate that geometry-conditioned diffusion provides an effective and supervision-efficient pathway toward occlusion-robust inbed pose estimation without modifying the sensing pipeline. The code is available at: github.com/navidTerraNova/ GeoDiffPose.
The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN) predictions and clinically actionable insights for brain tumor classification, leveraging large language models (LLMs) to deliver human-interpretable diagnostic narratives. The proposed framework operates through three coupled stages. First, nine CNN architectures are extended with a dual-output hybrid formulation that simultaneously optimises a classification head and a segmentation head, enabling spatially richer feature learning. Second, visual saliency attribution methods, namely Grad-CAM, Grad-CAM++, and ScoreCAM, are applied to generate class-discriminative heatmaps, which are subsequently refined into binary tumor masks via an adaptive percentile thresholding pipeline. Third, the resulting masks are mapped onto the Harvard-Oxford cortical atlas to translate pixel-level evidence into named neuroanatomical structures, and the extracted findings are encoded into a structured JSON file that conditions three LLMs (Grok3, Mistral, and LLaMA) to generate coherent, radiological-style diagnostic reports. Evaluated on a dataset of 4,834 contrast-enhanced T1-weighted brain MRI images spanning three tumor classes, InceptionResNetV2 achieved the highest classification performance and Grad-CAM++ yielded the best segmentation overlap. Among the language models, Grok3 led in lexical diversity and coherence, while LLaMA achieved the highest readability score. By integrating visual, anatomical, and linguistic modalities into a unified pipeline, the framework produces explanations that are technically grounded and meaningfully interpretable, advancing the transparency and clinical accountability of artificial intelligence assisted brain tumor diagnosis.
Robotic ultrasound has advanced local image-driven control, contact regulation, and view optimization, yet current systems lack the anatomical understanding needed to determine what to scan, where to begin, and how to adapt to individual patient anatomy. These gaps make systems still reliant on expert intervention to initiate scanning. Here we present SAMe, a semantic anatomy mapping engine that provides robotic ultrasound with an explicit anatomical prior layer. SAMe addresses scan initiation as a target-to-anatomy-to-action process: it grounds under-specified clinical complaints into structured target organs, instantiates a patient-specific anatomical representation for the grounded targets from a single external body image, and translates this representation into control-facing 6-DoF probe initialization states without any additional registration using preoperative CT or MRI. The anatomical representation maintained by SAMe is explicit, lightweight (single-organ inference in 0.08s), and compatible with downstream control by design. Across semantic grounding, anatomical instantiation, and real-robot evaluation, SAMe shows strong performance across the full initialization pipeline. In real-robot experiments, SAMe achieved overall organ-hit rates of 97.3% for liver initialization and 81.7% for kidney initialization across the evaluated target sets. Even when restricted to the centroid target, SAMe outperformed the surface-heuristic baseline for both liver and kidney initialization. These results establish an explicit anatomical prior layer that addresses scan initialization and is designed to support broader downstream autonomous scanning pipelines, providing the anatomical foundation for complaint-driven, anatomically informed robotic ultrasonography.
When orthodontists trace cephalometric radiographs, they follow a structured workflow: identify the soft tissue profile, partition the skull into anatomical regions, trace contours, and locate landmarks using geometric definitions -- yet no automated system replicates this reasoning. We present a five-phase anatomy-guided initialization pipeline that translates this clinical workflow into computational operations, producing confidence-weighted spatial attention priors for a downstream HRNet-W32 detector. On 1,502 radiographs from three sources spanning 7+ imaging devices, the system achieves 1.04 mm mean radial error on 25 landmarks -- surpassing prior state-of-the-art (1.23 mm on 19 landmarks) by 15.4%, with twelve landmarks below 1 mm. A three-way controlled ablation reveals two striking findings. First, removing anatomical priors does not merely slow convergence -- it destroys generalization: both models converge to ~1.03 mm on validation, but diverge to 1.94 vs. 1.04 mm on the test set. Second, replacing anatomical priors with random-position Gaussians produces even worse generalization (2.24 mm), confirming that the improvement derives from anatomically correct positioning, not additional input channels. Clinical domain knowledge encoded as spatial priors provides an inductive bias that architecture and data augmentation alone do not provide.
Optical chemical structure recognition (OCSR) translates molecular images into machine-readable representations like SMILES strings or molecular graphs, but remains challenging in real-world documents due to inexhaustible variations in chemical structures, shorthand conventions, and visual noise. Most existing deep-learning-based approaches rely on teacher forcing with token-level Maximum Likelihood Estimation (MLE). This training paradigm suffers from exposure bias, as models are trained under ground-truth prefixes but must condition on their own previous predictions during inference. Moreover, token-level MLE objectives hinder the optimization towards molecular-level evaluation criteria such as chemical validity and structural similarity. Here we introduce Minimum Risk Training (MRT) to OCSR and propose COMO (Closed-loop Optical Molecule recOgnition), a closed-loop framework that mitigates exposure bias by directly optimizing over molecule-level, non-differentiable objectives, by iteratively sampling and evaluating the model's own predictions. Experiments on ten benchmarks including synthetic and real-world chemical diagrams from patent and scientific literature demonstrate that COMO substantially outperforms existing rule-based and learning-based methods with less training data. Ablation studies further show that MRT is architecture-agnostic, demonstrating its potential for broad application to end-to-end OCSR systems.
Frequency diverse arrays (FDA) have attracted sustained interest as a promising architecture for introducing range-dependent responses into array systems. Unlike conventional phased arrays (PA), whose transmit behavior is primarily angle-dependent, FDA employs inter-element frequency offsets to generate time-and range-dependent phase structures, thereby producing a joint time-range-angle array response. Despite extensive research, the physical meaning of FDA-induced degrees of freedom remains debated, particularly in relation to range-angle coupling, the feasibility of time-invariant focusing, and the distinction between frequency-driven and waveform-driven range selectivity. This paper reexamines FDA from a structural and manifold-based perspective. A central contribution is the introduction of an irreducibility criterion, which distinguishes genuine range-domain physical degrees of freedom from effects that can be reproduced by equivalent signal-processing transformations. Based on this perspective, PA, multiple-input multiple-output (MIMO), FDA, and FDA-MIMO are comparatively interpreted according to the physical origin of their effective degrees of freedom, including spatial phase, waveform orthogonality, frequency gradients, and their interaction. The paper further clarifies the role of frequency across different array paradigms, contrasts FDA with time-coding-based architectures, and explains how key FDA properties such as manifold expansion, range--angle coupling, time variation, and multi-frequency diversity translate into system capabilities. Building on these structural insights, the paper connects FDA to a broad range of radar and communication functionalities, including parameter estimation, target detection, imaging, physical-layer security, and integrated sensing and communication.