Do Emotions in Prompts Matter? Effects of Emotional Framing on Large Language Models

Emotional tone is pervasive in human communication, yet its influence on large language model (LLM) behaviour remains unclear. Here, we examine how first-person emotional framing in user-side queries affect LLM performance across six benchmark domains, including mathematical reasoning, medical question answering, reading comprehension, commonsense reasoning and social inference. Across models and tasks, static emotional prefixes usually produce only small changes in accuracy, suggesting that affective phrasing is typically a mild perturbation rather than a reliable general-purpose intervention. This stability is not uniform: effects are more variable in socially grounded tasks, where emotional context more plausibly interacts with interpersonal reasoning. Additional analyses show that stronger emotional wording induces only modest extra change, and that human-written prefixes reproduce the same qualitative pattern as LLM-generated ones. We then introduce EmotionRL, an adaptive emotional prompting framework that selects emotional framing adaptively for each query. Although no single emotion is consistently beneficial, adaptive selection yields more reliable gains than fixed emotional prompting. Together, these findings show that emotional tone is neither a dominant driver of LLM performance nor irrelevant noise, but a weak and input-dependent signal that can be exploited through adaptive control.

Procela: Epistemic Governance in Mechanistic Simulations Under Structural Uncertainty

Mechanistic simulations typically assume fixed ontologies: variables, causal relationships, and resolution policies are static. This assumption fails when the true causal structure is contested or unidentifiable-as in antimicrobial resistance (AMR) spread, where contact, environmental, and selection ontologies compete. We introduce Procela, a Python framework where variables act as epistemic authorities that maintain complete hypothesis memory, mechanisms encode competing ontologies as causal units, and governance observes epistemic signals and mutates system topology at runtime. This is the first framework where simulations test their own assumptions. We instantiate Procela for AMR in a hospital network with three competing families. Governance detects coverage decay, policy fragility, and runs structural probes. Results show 20.4% error reduction and 69% cumulative regret improvement over baseline. All experiments are reproducible with full auditability. Procela establishes a new paradigm: simulations that model not only the world but their own modeling process, enabling adaptation under structural uncertainty.

Go Big or Go Home: Simulating Mobbing Behavior with Braitenbergian Robots

We used the Webots robotics simulation platform to simulate a dyadic avoiding and mobbing predator behavior in a group of Braitenbergian robots. Mobbing is an antipredator adaptation used by some animals in which the individuals cooperatively attack or harass a predator to protect themselves. One way of coordinating a mobbing attack is using mobbing calls to summon other individuals of the mobbing species. We imitated this mechanism and simulated Braitenbergian robots that use mobbing calls when they face a light source (representing an inanimate predator) and mob it if they can summon allies, otherwise, they escape from it. We explore the effects of range of mobbing call (infinite range, mid-range and low-range) and the size of the robot group (ten robots vs three) on the overall success of mobbing. Our results suggest that both variables have significant impacts. This work has implications for simulations of action selection in artificial life and designing control architectures for autonomous agents.

Predicting Neuromodulation Outcome for Parkinson's Disease with Generative Virtual Brain Model

Parkinson's disease (PD) affects over ten million people worldwide. Although temporal interference (TI) and deep brain stimulation (DBS) are promising therapies, inter-individual variability limits empirical treatment selection, increasing non-negligible surgical risk and cost. Previous explorations either resort to limited statistical biomarkers that are insufficient to characterize variability, or employ AI-driven methods which is prone to overfitting and opacity. We bridge this gap with a pretraining-finetuning framework to predict outcomes directly from resting-state fMRI. Critically, a generative virtual brain foundation model, pretrained on a collective dataset (2707 subjects, 5621 sessions) to capture universal disorder patterns, was finetuned on PD cohorts receiving TI (n=51) or DBS (n=55) to yield individualized virtual brains with high fidelity to empirical functional connectivity (r=0.935). By constructing counterfactual estimations between pathological and healthy neural states within these personalized models, we predicted clinical responses (TI: AUPR=0.853; DBS: AUPR=0.915), substantially outperforming baselines. External and prospective validations (n=14, n=11) highlight the feasibility of clinical translation. Moreover, our framework provides state-dependent regional patterns linked to response, offering hypothesis-generating mechanistic insights.

SurgTEMP: Temporal-Aware Surgical Video Question Answering with Text-guided Visual Memory for Laparoscopic Cholecystectomy

Surgical procedures are inherently complex and risky, requiring extensive expertise and constant focus to well navigate evolving intraoperative scenes. Computer-assisted systems such as surgical visual question answering (VQA) offer promises for education and intraoperative support. Current surgical VQA research largely focuses on static frame analysis, overlooking rich temporal semantics. Surgical video question answering is further challenged by low visual contrast, its highly knowledge-driven nature, diverse analytical needs spanning scattered temporal windows, and the hierarchy from basic perception to high-level intraoperative assessment. To address these challenges, we propose SurgTEMP, a multimodal LLM framework featuring (i) a query-guided token selection module that builds hierarchical visual memory (spatial and temporal memory banks) and (ii) a Surgical Competency Progression (SCP) training scheme. Together, these components enable effective modeling of variable-length surgical videos while preserving procedure-relevant cues and temporal coherence, and better support diverse downstream assessment tasks. To support model development, we introduce CholeVidQA-32K, a surgical video question answering dataset comprising 32K open-ended QA pairs and 3,855 video segments (approximately 128 h total) from laparoscopic cholecystectomy. The dataset is organized into a three-level hierarchy -- Perception, Assessment, and Reasoning -- spanning 11 tasks from instrument/action/anatomy perception to Critical View of Safety (CVS), intraoperative difficulty, skill proficiency, and adverse event assessment. In comprehensive evaluations against state-of-the-art open-source multimodal and video LLMs (fine-tuned and zero-shot), SurgTEMP achieves substantial performance improvements, advancing the state of video-based surgical VQA.

CLIP-AUTT: Test-Time Personalization with Action Unit Prompting for Fine-Grained Video Emotion Recognition

Personalization in emotion recognition (ER) is essential for an accurate interpretation of subtle and subject-specific expressive patterns. Recent advances in vision-language models (VLMs) such as CLIP demonstrate strong potential for leveraging joint image-text representations in ER. However, CLIP-based methods either depend on CLIP's contrastive pretraining or on LLMs to generate descriptive text prompts, which are noisy, computationally expensive, and fail to capture fine-grained expressions, leading to degraded performance. In this work, we leverage Action Units (AUs) as structured textual prompts within CLIP to model fine-grained facial expressions. AUs encode the subtle muscle activations underlying expressions, providing localized and interpretable semantic cues for more robust ER. We introduce CLIP-AU, a lightweight AU-guided temporal learning method that integrates interpretable AU semantics into CLIP. It learns generic, subject-agnostic representations by aligning AU prompts with facial dynamics, enabling fine-grained ER without CLIP fine-tuning or LLM-generated text supervision. Although CLIP-AU models fine-grained AU semantics, it does not adapt to subject-specific variability in subtle expressions. To address this limitation, we propose CLIP-AUTT, a video-based test-time personalization method that dynamically adapts AU prompts to videos from unseen subjects. By combining entropy-guided temporal window selection with prompt tuning, CLIP-AUTT enables subject-specific adaptation while preserving temporal consistency. Our extensive experiments on three challenging video-based subtle ER datasets, BioVid, StressID, and BAH, indicate that CLIP-AU and CLIP-AUTT outperform state-of-the-art CLIP-based FER and TTA methods, achieving robust and personalized subtle ER. Our code is publicly available at: https://github.com/osamazeeshan/CLIP-AUTT.

Transfer Learning in Bayesian Optimization for Aircraft Design

The use of transfer learning within Bayesian optimization addresses the disadvantages of the so-called \textit{cold start} problem by using source data to aid in the optimization of a target problem. We present a method that leverages an ensemble of surrogate models using transfer learning and integrates it in a constrained Bayesian optimization framework. We identify challenges particular to aircraft design optimization related to heterogeneous design variables and constraints. We propose the use of a partial-least-squares dimension reduction algorithm to address design space heterogeneity, and a \textit{meta} data surrogate selection method to address constraint heterogeneity. Numerical benchmark problems and an aircraft conceptual design optimization problem are used to demonstrate the proposed methods. Results show significant improvement in convergence in early optimization iterations compared to standard Bayesian optimization, with improved prediction accuracy for both objective and constraint surrogate models.

Automating Early Disease Prediction Via Structured and Unstructured Clinical Data

This study presents a fully automated methodology for early prediction studies in clinical settings, leveraging information extracted from unstructured discharge reports. The proposed pipeline uses discharge reports to support the three main steps of early prediction: cohort selection, dataset generation, and outcome labeling. By processing discharge reports with natural language processing techniques, we can efficiently identify relevant patient cohorts, enrich structured datasets with additional clinical variables, and generate high-quality labels without manual intervention. This approach addresses the frequent issue of missing or incomplete data in codified electronic health records (EHR), capturing clinically relevant information that is often underrepresented. We evaluate the methodology in the context of predicting atrial fibrillation (AF) progression, showing that predictive models trained on datasets enriched with discharge report information achieve higher accuracy and correlation with true outcomes compared to models trained solely on structured EHR data, while also surpassing traditional clinical scores. These results demonstrate that automating the integration of unstructured clinical text can streamline early prediction studies, improve data quality, and enhance the reliability of predictive models for clinical decision-making.

Trust-Aware Routing for Distributed Generative AI Inference at the Edge

Emerging deployments of Generative AI increasingly execute inference across decentralized and heterogeneous edge devices rather than on a single trusted server. In such environments, a single device failure or misbehavior can disrupt the entire inference process, making traditional best-effort peer-to-peer routing insufficient. Coordinating distributed generative inference therefore requires mechanisms that explicitly account for reliability, performance variability, and trust among participating peers. In this paper, we present G-TRAC, a trust-aware coordination framework that integrates algorithmic path selection with system-level protocol design to ensure robust distributed inference. First, we formulate the routing problem as a \textit{Risk-Bounded Shortest Path} computation and introduce a polynomial-time solution that combines trust-floor pruning with Dijkstra's search, achieving sub-millisecond median routing latency at practical edge scales, and remaining below 10 ms at larger scales. Second, to operationally support the routing logic in dynamic environments, the framework employs a \textit{Hybrid Trust Architecture} that maintains global reputation state at stable anchors while disseminating lightweight updates to edge peers via background synchronization. Experimental evaluation on a heterogeneous testbed of commodity devices demonstrates that G-TRAC significantly improves inference completion rates, effectively isolates unreliable peers, and sustains robust execution even under node failures and network partitions.

Complete Causal Identification from Ancestral Graphs under Selection Bias

Many causal discovery algorithms, including the celebrated FCI algorithm, output a Partial Ancestral Graph (PAG). PAGs serve as an abstract graphical representation of the underlying causal structure, modeled by directed acyclic graphs with latent and selection variables. This paper develops a characterization of the set of extended-type conditional independence relations that are invariant across all causal models represented by a PAG. This theory allows us to formulate a general measure-theoretic version of Pearl's causal calculus and a sound and complete identification algorithm for PAGs under selection bias. Our results also apply when PAGs are learned by certain algorithms that integrate observational data with experimental data and incorporate background knowledge.