Learning from Sparse Point Labels for Dense Carcinosis Localization in Advanced Ovarian Cancer Assessment

Learning from sparse labels is a challenge commonplace in the medical domain. This is due to numerous factors, such as annotation cost, and is especially true for newly introduced tasks. When dense pixel-level annotations are needed, this becomes even more unfeasible. However, being able to learn from just a few annotations at the pixel-level, while extremely difficult and underutilized, can drive progress in studies where perfect annotations are not immediately available. This work tackles the challenge of learning the dense prediction task of keypoint localization from a few point annotations in the context of 2d carcinosis keypoint localization from laparoscopic video frames for diagnostic planning of advanced ovarian cancer patients. To enable this, we formulate the problem as a sparse heatmap regression from a few point annotations per image and propose a new loss function, called Crag and Tail loss, for efficient learning. Our proposed loss function effectively leverages positive sparse labels while minimizing the impact of false negatives or missed annotations. Through an extensive ablation study, we demonstrate the effectiveness of our approach in achieving accurate dense localization of carcinosis keypoints, highlighting its potential to advance research in scenarios where dense annotations are challenging to obtain.

Surgeons Awareness, Expectations, and Involvement with Artificial Intelligence: a Survey Pre and Post the GPT Era

Artificial Intelligence (AI) is transforming medicine, with generative AI models like ChatGPT reshaping perceptions of its potential. This study examines surgeons' awareness, expectations, and involvement with AI in surgery through comparative surveys conducted in 2021 and 2024. Two cross-sectional surveys were distributed globally in 2021 and 2024, the first before an IRCAD webinar and the second during the annual EAES meeting. The surveys assessed demographics, AI awareness, expectations, involvement, and ethics (2024 only). The surveys collected a total of 671 responses from 98 countries, 522 in 2021 and 149 in 2024. Awareness of AI courses rose from 14.5% in 2021 to 44.6% in 2024, while course attendance increased from 12.9% to 23%. Despite this, familiarity with foundational AI concepts remained limited. Expectations for AI's role shifted in 2024, with hospital management gaining relevance. Ethical concerns gained prominence, with 87.2% of 2024 participants emphasizing accountability and transparency. Infrastructure limitations remained the primary obstacle to implementation. Interdisciplinary collaboration and structured training were identified as critical for successful AI adoption. Optimism about AI's transformative potential remained high, with 79.9% of respondents believing AI would positively impact surgery and 96.6% willing to integrate AI into their clinical practice. Surgeons' perceptions of AI are evolving, driven by the rise of generative AI and advancements in surgical data science. While enthusiasm for integration is strong, knowledge gaps and infrastructural challenges persist. Addressing these through education, ethical frameworks, and infrastructure development is essential.

A Skull-Adaptive Framework for AI-Based 3D Transcranial Focused Ultrasound Simulation

Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the heterogeneous and anisotropic nature of the human skull introduces significant distortions to the propagating ultrasound wavefront, which require time-consuming patient-specific planning and corrections using numerical solvers for accurate targeting. To enable data-driven approaches in this domain, we introduce TFUScapes, the first large-scale, high-resolution dataset of tFUS simulations through anatomically realistic human skulls derived from T1-weighted MRI images. We have developed a scalable simulation engine pipeline using the k-Wave pseudo-spectral solver, where each simulation returns a steady-state pressure field generated by a focused ultrasound transducer placed at realistic scalp locations. In addition to the dataset, we present DeepTFUS, a deep learning model that estimates normalized pressure fields directly from input 3D CT volumes and transducer position. The model extends a U-Net backbone with transducer-aware conditioning, incorporating Fourier-encoded position embeddings and MLP layers to create global transducer embeddings. These embeddings are fused with U-Net encoder features via feature-wise modulation, dynamic convolutions, and cross-attention mechanisms. The model is trained using a combination of spatially weighted and gradient-sensitive loss functions, enabling it to approximate high-fidelity wavefields. The TFUScapes dataset is publicly released to accelerate research at the intersection of computational acoustics, neurotechnology, and deep learning. The project page is available at https://github.com/CAMMA-public/TFUScapes.

Feature Mixing Approach for Detecting Intraoperative Adverse Events in Laparoscopic Roux-en-Y Gastric Bypass Surgery

Intraoperative adverse events (IAEs), such as bleeding or thermal injury, can lead to severe postoperative complications if undetected. However, their rarity results in highly imbalanced datasets, posing challenges for AI-based detection and severity quantification. We propose BetaMixer, a novel deep learning model that addresses these challenges through a Beta distribution-based mixing approach, converting discrete IAE severity scores into continuous values for precise severity regression (0-5 scale). BetaMixer employs Beta distribution-based sampling to enhance underrepresented classes and regularizes intermediate embeddings to maintain a structured feature space. A generative approach aligns the feature space with sampled IAE severity, enabling robust classification and severity regression via a transformer. Evaluated on the MultiBypass140 dataset, which we extended with IAE labels, BetaMixer achieves a weighted F1 score of 0.76, recall of 0.81, PPV of 0.73, and NPV of 0.84, demonstrating strong performance on imbalanced data. By integrating Beta distribution-based sampling, feature mixing, and generative modeling, BetaMixer offers a robust solution for IAE detection and quantification in clinical settings.

CoSimGen: Controllable Diffusion Model for Simultaneous Image and Mask Generation

The acquisition of annotated datasets with paired images and segmentation masks is a critical challenge in domains such as medical imaging, remote sensing, and computer vision. Manual annotation demands significant resources, faces ethical constraints, and depends heavily on domain expertise. Existing generative models often target single-modality outputs, either images or segmentation masks, failing to address the need for high-quality, simultaneous image-mask generation. Additionally, these models frequently lack adaptable conditioning mechanisms, restricting control over the generated outputs and limiting their applicability for dataset augmentation and rare scenario simulation. We propose CoSimGen, a diffusion-based framework for controllable simultaneous image and mask generation. Conditioning is intuitively achieved through (1) text prompts grounded in class semantics, (2) spatial embedding of context prompts to provide spatial coherence, and (3) spectral embedding of timestep information to model noise levels during diffusion. To enhance controllability and training efficiency, the framework incorporates contrastive triplet loss between text and class embeddings, alongside diffusion and adversarial losses. Initial low-resolution outputs 128 x 128 are super-resolved to 512 x 512, producing high-fidelity images and masks with strict adherence to conditions. We evaluate CoSimGen on metrics such as FID, KID, LPIPS, Class FID, Positive predicted value for image fidelity and semantic alignment of generated samples over 4 diverse datasets. CoSimGen achieves state-of-the-art performance across all datasets, achieving the lowest KID of 0.11 and LPIPS of 0.53 across datasets.

fine-CLIP: Enhancing Zero-Shot Fine-Grained Surgical Action Recognition with Vision-Language Models

While vision-language models like CLIP have advanced zero-shot surgical phase recognition, they struggle with fine-grained surgical activities, especially action triplets. This limitation arises because current CLIP formulations rely on global image features, which overlook the fine-grained semantics and contextual details crucial for complex tasks like zero-shot triplet recognition. Furthermore, these models do not explore the hierarchical structure inherent in triplets, reducing their ability to generalize to novel triplets. To address these challenges, we propose fine-CLIP, which learns object-centric features and lever- ages the hierarchy in triplet formulation. Our approach integrates three components: hierarchical prompt modeling to capture shared semantics, LoRA-based vision backbone adaptation for enhanced feature extraction, and a graph-based condensation strategy that groups similar patch features into meaningful object clusters. Since triplet classification is a challenging task, we introduce an alternative yet meaningful base-to-novel generalization benchmark with two settings on the CholecT50 dataset: Unseen-Target, assessing adaptability to triplets with novel anatomical structures, and Unseen-Instrument-Verb, where models need to generalize to novel instrument-verb interactions. fine-CLIP shows significant improvements in F1 and mAP, enhancing zero-shot recognition of novel surgical triplets.

Learning from Synchronization: Self-Supervised Uncalibrated Multi-View Person Association in Challenging Scenes

Multi-view person association is a fundamental step towards multi-view analysis of human activities. Although the person re-identification features have been proven effective, they become unreliable in challenging scenes where persons share similar appearances. Therefore, cross-view geometric constraints are required for a more robust association. However, most existing approaches are either fully-supervised using ground-truth identity labels or require calibrated camera parameters that are hard to obtain. In this work, we investigate the potential of learning from synchronization, and propose a self-supervised uncalibrated multi-view person association approach, Self-MVA, without using any annotations. Specifically, we propose a self-supervised learning framework, consisting of an encoder-decoder model and a self-supervised pretext task, cross-view image synchronization, which aims to distinguish whether two images from different views are captured at the same time. The model encodes each person's unified geometric and appearance features, and we train it by utilizing synchronization labels for supervision after applying Hungarian matching to bridge the gap between instance-wise and image-wise distances. To further reduce the solution space, we propose two types of self-supervised linear constraints: multi-view re-projection and pairwise edge association. Extensive experiments on three challenging public benchmark datasets (WILDTRACK, MVOR, and SOLDIERS) show that our approach achieves state-of-the-art results, surpassing existing unsupervised and fully-supervised approaches. Code is available at https://github.com/CAMMA-public/Self-MVA.

S4M: Segment Anything with 4 Extreme Points

The Segment Anything Model (SAM) has revolutionized open-set interactive image segmentation, inspiring numerous adapters for the medical domain. However, SAM primarily relies on sparse prompts such as point or bounding box, which may be suboptimal for fine-grained instance segmentation, particularly in endoscopic imagery, where precise localization is critical and existing prompts struggle to capture object boundaries effectively. To address this, we introduce S4M (Segment Anything with 4 Extreme Points), which augments SAM by leveraging extreme points -- the top-, bottom-, left-, and right-most points of an instance -- prompts. These points are intuitive to identify and provide a faster, structured alternative to box prompts. However, a na\"ive use of extreme points degrades performance, due to SAM's inability to interpret their semantic roles. To resolve this, we introduce dedicated learnable embeddings, enabling the model to distinguish extreme points from generic free-form points and better reason about their spatial relationships. We further propose an auxiliary training task through the Canvas module, which operates solely on prompts -- without vision input -- to predict a coarse instance mask. This encourages the model to internalize the relationship between extreme points and mask distributions, leading to more robust segmentation. S4M outperforms other SAM-based approaches on three endoscopic surgical datasets, demonstrating its effectiveness in complex scenarios. Finally, we validate our approach through a human annotation study on surgical endoscopic videos, confirming that extreme points are faster to acquire than bounding boxes.

Multi-view Video-Pose Pretraining for Operating Room Surgical Activity Recognition

Understanding the workflow of surgical procedures in complex operating rooms requires a deep understanding of the interactions between clinicians and their environment. Surgical activity recognition (SAR) is a key computer vision task that detects activities or phases from multi-view camera recordings. Existing SAR models often fail to account for fine-grained clinician movements and multi-view knowledge, or they require calibrated multi-view camera setups and advanced point-cloud processing to obtain better results. In this work, we propose a novel calibration-free multi-view multi-modal pretraining framework called Multiview Pretraining for Video-Pose Surgical Activity Recognition PreViPS, which aligns 2D pose and vision embeddings across camera views. Our model follows CLIP-style dual-encoder architecture: one encoder processes visual features, while the other encodes human pose embeddings. To handle the continuous 2D human pose coordinates, we introduce a tokenized discrete representation to convert the continuous 2D pose coordinates into discrete pose embeddings, thereby enabling efficient integration within the dual-encoder framework. To bridge the gap between these two modalities, we propose several pretraining objectives using cross- and in-modality geometric constraints within the embedding space and incorporating masked pose token prediction strategy to enhance representation learning. Extensive experiments and ablation studies demonstrate improvements over the strong baselines, while data-efficiency experiments on two distinct operating room datasets further highlight the effectiveness of our approach. We highlight the benefits of our approach for surgical activity recognition in both multi-view and single-view settings, showcasing its practical applicability in complex surgical environments. Code will be made available at: https://github.com/CAMMA-public/PreViPS.

When do they StOP?: A First Step Towards Automatically Identifying Team Communication in the Operating Room

Purpose: Surgical performance depends not only on surgeons' technical skills but also on team communication within and across the different professional groups present during the operation. Therefore, automatically identifying team communication in the OR is crucial for patient safety and advances in the development of computer-assisted surgical workflow analysis and intra-operative support systems. To take the first step, we propose a new task of detecting communication briefings involving all OR team members, i.e. the team Time-out and the StOP?-protocol, by localizing their start and end times in video recordings of surgical operations. Methods: We generate an OR dataset of real surgeries, called Team-OR, with more than one hundred hours of surgical videos captured by the multi-view camera system in the OR. The dataset contains temporal annotations of 33 Time-out and 22 StOP?-protocol activities in total. We then propose a novel group activity detection approach, where we encode both scene context and action features, and use an efficient neural network model to output the results. Results: The experimental results on the Team-OR dataset show that our approach outperforms existing state-of-the-art temporal action detection approaches. It also demonstrates the lack of research on group activities in the OR, proving the significance of our dataset. Conclusion: We investigate the Team Time-Out and the StOP?-protocol in the OR, by presenting the first OR dataset with temporal annotations of group activities protocols, and introducing a novel group activity detection approach that outperforms existing approaches. Code is available at https://github.com/CAMMA-public/Team-OR .