Unified Start, Personalized End: Progressive Pruning for Efficient 3D Medical Image Segmentation

3D medical image segmentation often faces heavy resource and time consumption, limiting its scalability and rapid deployment in clinical environments. Existing efficient segmentation models are typically static and manually designed prior to training, which restricts their adaptability across diverse tasks and makes it difficult to balance performance with resource efficiency. In this paper, we propose PSP-Seg, a progressive pruning framework that enables dynamic and efficient 3D segmentation. PSP-Seg begins with a redundant model and iteratively prunes redundant modules through a combination of block-wise pruning and a functional decoupling loss. We evaluate PSP-Seg on five public datasets, benchmarking it against seven state-of-the-art models and six efficient segmentation models. Results demonstrate that the lightweight variant, PSP-Seg-S, achieves performance on par with nnU-Net while reducing GPU memory usage by 42-45%, training time by 29-48%, and parameter number by 83-87% across all datasets. These findings underscore PSP-Seg's potential as a cost-effective yet high-performing alternative for widespread clinical application.

Sparse Transformer for Ultra-sparse Sampled Video Compressive Sensing

Digital cameras consume ~0.1 microjoule per pixel to capture and encode video, resulting in a power usage of ~20W for a 4K sensor operating at 30 fps. Imagining gigapixel cameras operating at 100-1000 fps, the current processing model is unsustainable. To address this, physical layer compressive measurement has been proposed to reduce power consumption per pixel by 10-100X. Video Snapshot Compressive Imaging (SCI) introduces high frequency modulation in the optical sensor layer to increase effective frame rate. A commonly used sampling strategy of video SCI is Random Sampling (RS) where each mask element value is randomly set to be 0 or 1. Similarly, image inpainting (I2P) has demonstrated that images can be recovered from a fraction of the image pixels. Inspired by I2P, we propose Ultra-Sparse Sampling (USS) regime, where at each spatial location, only one sub-frame is set to 1 and all others are set to 0. We then build a Digital Micro-mirror Device (DMD) encoding system to verify the effectiveness of our USS strategy. Ideally, we can decompose the USS measurement into sub-measurements for which we can utilize I2P algorithms to recover high-speed frames. However, due to the mismatch between the DMD and CCD, the USS measurement cannot be perfectly decomposed. To this end, we propose BSTFormer, a sparse TransFormer that utilizes local Block attention, global Sparse attention, and global Temporal attention to exploit the sparsity of the USS measurement. Extensive results on both simulated and real-world data show that our method significantly outperforms all previous state-of-the-art algorithms. Additionally, an essential advantage of the USS strategy is its higher dynamic range than that of the RS strategy. Finally, from the application perspective, the USS strategy is a good choice to implement a complete video SCI system on chip due to its fixed exposure time.

A Survey of Scientific Large Language Models: From Data Foundations to Agent Frontiers

Scientific Large Language Models (Sci-LLMs) are transforming how knowledge is represented, integrated, and applied in scientific research, yet their progress is shaped by the complex nature of scientific data. This survey presents a comprehensive, data-centric synthesis that reframes the development of Sci-LLMs as a co-evolution between models and their underlying data substrate. We formulate a unified taxonomy of scientific data and a hierarchical model of scientific knowledge, emphasizing the multimodal, cross-scale, and domain-specific challenges that differentiate scientific corpora from general natural language processing datasets. We systematically review recent Sci-LLMs, from general-purpose foundations to specialized models across diverse scientific disciplines, alongside an extensive analysis of over 270 pre-/post-training datasets, showing why Sci-LLMs pose distinct demands -- heterogeneous, multi-scale, uncertainty-laden corpora that require representations preserving domain invariance and enabling cross-modal reasoning. On evaluation, we examine over 190 benchmark datasets and trace a shift from static exams toward process- and discovery-oriented assessments with advanced evaluation protocols. These data-centric analyses highlight persistent issues in scientific data development and discuss emerging solutions involving semi-automated annotation pipelines and expert validation. Finally, we outline a paradigm shift toward closed-loop systems where autonomous agents based on Sci-LLMs actively experiment, validate, and contribute to a living, evolving knowledge base. Collectively, this work provides a roadmap for building trustworthy, continually evolving artificial intelligence (AI) systems that function as a true partner in accelerating scientific discovery.

A Question Answering Dataset for Temporal-Sensitive Retrieval-Augmented Generation

We introduce ChronoQA, a large-scale benchmark dataset for Chinese question answering, specifically designed to evaluate temporal reasoning in Retrieval-Augmented Generation (RAG) systems. ChronoQA is constructed from over 300,000 news articles published between 2019 and 2024, and contains 5,176 high-quality questions covering absolute, aggregate, and relative temporal types with both explicit and implicit time expressions. The dataset supports both single- and multi-document scenarios, reflecting the real-world requirements for temporal alignment and logical consistency. ChronoQA features comprehensive structural annotations and has undergone multi-stage validation, including rule-based, LLM-based, and human evaluation, to ensure data quality. By providing a dynamic, reliable, and scalable resource, ChronoQA enables structured evaluation across a wide range of temporal tasks, and serves as a robust benchmark for advancing time-sensitive retrieval-augmented question answering systems.

VSI: Visual Subtitle Integration for Keyframe Selection to enhance Long Video Understanding

Long video understanding presents a significant challenge to multimodal large language models (MLLMs) primarily due to the immense data scale. A critical and widely adopted strategy for making this task computationally tractable is keyframe retrieval, which seeks to identify a sparse set of video frames that are most salient to a given textual query. However, the efficacy of this approach is hindered by weak multimodal alignment between textual queries and visual content and fails to capture the complex temporal semantic information required for precise reasoning. To address this, we propose Visual-Subtitle Integeration(VSI), a multimodal keyframe search method that integrates subtitles, timestamps, and scene boundaries into a unified multimodal search process. The proposed method captures the visual information of video frames as well as the complementary textual information through a dual-stream search mechanism by Video Search Stream as well as Subtitle Match Stream, respectively, and improves the keyframe search accuracy through the interaction of the two search streams. Experimental results show that VSI achieve 40.00% key frame localization accuracy on the text-relevant subset of LongVideoBench and 68.48% accuracy on downstream long Video-QA tasks, surpassing competitive baselines by 20.35% and 15.79%, respectively. Furthermore, on the LongVideoBench, VSI achieved state-of-the-art(SOTA) in medium-to-long video-QA tasks, demonstrating the robustness and generalizability of the proposed multimodal search strategy.

RLVMR: Reinforcement Learning with Verifiable Meta-Reasoning Rewards for Robust Long-Horizon Agents

The development of autonomous agents for complex, long-horizon tasks is a central goal in AI. However, dominant training paradigms face a critical limitation: reinforcement learning (RL) methods that optimize solely for final task success often reinforce flawed or inefficient reasoning paths, a problem we term inefficient exploration. This leads to agents that are brittle and fail to generalize, as they learn to find solutions without learning how to reason coherently. To address this, we introduce RLVMR, a novel framework that integrates dense, process-level supervision into end-to-end RL by rewarding verifiable, meta-reasoning behaviors. RLVMR equips an agent to explicitly tag its cognitive steps, such as planning, exploration, and reflection, and provides programmatic, rule-based rewards for actions that contribute to effective problem-solving. These process-centric rewards are combined with the final outcome signal and optimized using a critic-free policy gradient method. On the challenging ALFWorld and ScienceWorld benchmarks, RLVMR achieves new state-of-the-art results, with our 7B model reaching an 83.6% success rate on the most difficult unseen task split. Our analysis confirms these gains stem from improved reasoning quality, including significant reductions in redundant actions and enhanced error recovery, leading to more robust, efficient, and interpretable agents.

Libra: Large Chinese-based Safeguard for AI Content

Large language models (LLMs) excel in text understanding and generation but raise significant safety and ethical concerns in high-stakes applications. To mitigate these risks, we present Libra-Guard, a cutting-edge safeguard system designed to enhance the safety of Chinese-based LLMs. Leveraging a two-stage curriculum training pipeline, Libra-Guard enhances data efficiency by employing guard pretraining on synthetic samples, followed by fine-tuning on high-quality, real-world data, thereby significantly reducing reliance on manual annotations. To enable rigorous safety evaluations, we also introduce Libra-Test, the first benchmark specifically designed to evaluate the effectiveness of safeguard systems for Chinese content. It covers seven critical harm scenarios and includes over 5,700 samples annotated by domain experts. Experiments show that Libra-Guard achieves 86.79% accuracy, outperforming Qwen2.5-14B-Instruct (74.33%) and ShieldLM-Qwen-14B-Chat (65.69%), and nearing closed-source models like Claude-3.5-Sonnet and GPT-4o. These contributions establish a robust framework for advancing the safety governance of Chinese LLMs and represent a tentative step toward developing safer, more reliable Chinese AI systems.

Enjoying Information Dividend: Gaze Track-based Medical Weakly Supervised Segmentation

Weakly supervised semantic segmentation (WSSS) in medical imaging struggles with effectively using sparse annotations. One promising direction for WSSS leverages gaze annotations, captured via eye trackers that record regions of interest during diagnostic procedures. However, existing gaze-based methods, such as GazeMedSeg, do not fully exploit the rich information embedded in gaze data. In this paper, we propose GradTrack, a framework that utilizes physicians' gaze track, including fixation points, durations, and temporal order, to enhance WSSS performance. GradTrack comprises two key components: Gaze Track Map Generation and Track Attention, which collaboratively enable progressive feature refinement through multi-level gaze supervision during the decoding process. Experiments on the Kvasir-SEG and NCI-ISBI datasets demonstrate that GradTrack consistently outperforms existing gaze-based methods, achieving Dice score improvements of 3.21\% and 2.61\%, respectively. Moreover, GradTrack significantly narrows the performance gap with fully supervised models such as nnUNet.

VISTA: Enhancing Vision-Text Alignment in MLLMs via Cross-Modal Mutual Information Maximization

Current multimodal large language models (MLLMs) face a critical challenge in modality alignment, often exhibiting a bias towards textual information at the expense of other modalities like vision. This paper conducts a systematic information-theoretic analysis of the widely used cross-entropy loss in MLLMs, uncovering its implicit alignment objective. Our theoretical investigation reveals that this implicit objective has inherent limitations, leading to a degradation of cross-modal alignment as text sequence length increases, thereby hindering effective multimodal information fusion. To overcome these drawbacks, we propose Vision-Text Alignment (VISTA), a novel approach guided by our theoretical insights. VISTA introduces an explicit alignment objective designed to maximize cross-modal mutual information, preventing the degradation of visual alignment. Notably, VISTA enhances the visual understanding capabilities of existing MLLMs without requiring any additional trainable modules or extra training data, making it both efficient and practical. Our method significantly outperforms baseline models across more than a dozen benchmark datasets, including VQAv2, MMStar, and MME, paving the way for new directions in MLLM modal alignment research.

Logic-in-Frames: Dynamic Keyframe Search via Visual Semantic-Logical Verification for Long Video Understanding

Understanding long video content is a complex endeavor that often relies on densely sampled frame captions or end-to-end feature selectors, yet these techniques commonly overlook the logical relationships between textual queries and visual elements. In practice, computational constraints necessitate coarse frame subsampling, a challenge analogous to ``finding a needle in a haystack.'' To address this issue, we introduce a semantics-driven search framework that reformulates keyframe selection under the paradigm of Visual Semantic-Logical Search. Specifically, we systematically define four fundamental logical dependencies: 1) spatial co-occurrence, 2) temporal proximity, 3) attribute dependency, and 4) causal order. These relations dynamically update frame sampling distributions through an iterative refinement process, enabling context-aware identification of semantically critical frames tailored to specific query requirements. Our method establishes new SOTA performance on the manually annotated benchmark in key-frame selection metrics. Furthermore, when applied to downstream video question-answering tasks, the proposed approach demonstrates the best performance gains over existing methods on LongVideoBench and Video-MME, validating its effectiveness in bridging the logical gap between textual queries and visual-temporal reasoning. The code will be publicly available.