Remote photoplethysmography (rPPG) is an important technique for perceiving human vital signs, which has received extensive attention. For a long time, researchers have focused on supervised methods that rely on large amounts of labeled data. These methods are limited by the requirement for large amounts of data and the difficulty of acquiring ground truth physiological signals. To address these issues, several self-supervised methods based on contrastive learning have been proposed. However, they focus on the contrastive learning between samples, which neglect the inherent self-similar prior in physiological signals and seem to have a limited ability to cope with noisy. In this paper, a linear self-supervised reconstruction task was designed for extracting the inherent self-similar prior in physiological signals. Besides, a specific noise-insensitive strategy was explored for reducing the interference of motion and illumination. The proposed framework in this paper, namely rPPG-MAE, demonstrates excellent performance even on the challenging VIPL-HR dataset. We also evaluate the proposed method on two public datasets, namely PURE and UBFC-rPPG. The results show that our method not only outperforms existing self-supervised methods but also exceeds the state-of-the-art (SOTA) supervised methods. One important observation is that the quality of the dataset seems more important than the size in self-supervised pre-training of rPPG. The source code is released at https://github.com/linuxsino/rPPG-MAE.
The availability of handy multi-modal (i.e., RGB-D) sensors has brought about a surge of face anti-spoofing research. However, the current multi-modal face presentation attack detection (PAD) has two defects: (1) The framework based on multi-modal fusion requires providing modalities consistent with the training input, which seriously limits the deployment scenario. (2) The performance of ConvNet-based model on high fidelity datasets is increasingly limited. In this work, we present a pure transformer-based framework, dubbed the Flexible Modal Vision Transformer (FM-ViT), for face anti-spoofing to flexibly target any single-modal (i.e., RGB) attack scenarios with the help of available multi-modal data. Specifically, FM-ViT retains a specific branch for each modality to capture different modal information and introduces the Cross-Modal Transformer Block (CMTB), which consists of two cascaded attentions named Multi-headed Mutual-Attention (MMA) and Fusion-Attention (MFA) to guide each modal branch to mine potential features from informative patch tokens, and to learn modality-agnostic liveness features by enriching the modal information of own CLS token, respectively. Experiments demonstrate that the single model trained based on FM-ViT can not only flexibly evaluate different modal samples, but also outperforms existing single-modal frameworks by a large margin, and approaches the multi-modal frameworks introduced with smaller FLOPs and model parameters.
Attenuation compensation (AC) is beneficial for visual interpretation tasks in single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI). However, traditional AC methods require the availability of a transmission scan, most often a CT scan. This approach has the disadvantages of increased radiation dose, increased scanner cost, and the possibility of inaccurate diagnosis in cases of misregistration between the SPECT and CT images. Further, many SPECT systems do not include a CT component. To address these issues, we developed a Scatter-window projection and deep Learning-based AC (SLAC) method to perform AC without a separate transmission scan. To investigate the clinical efficacy of this method, we then objectively evaluated the performance of this method on the clinical task of detecting perfusion defects on MPI in a retrospective study with anonymized clinical SPECT/CT stress MPI images. The proposed method was compared with CT-based AC (CTAC) and no-AC (NAC) methods. Our results showed that the SLAC method yielded an almost overlapping receiver operating characteristic (ROC) plot and a similar area under the ROC (AUC) to the CTAC method on this task. These results demonstrate the capability of the SLAC method for transmission-less AC in SPECT and motivate further clinical evaluation.
Artificial intelligence-based methods have generated substantial interest in nuclear medicine. An area of significant interest has been using deep-learning (DL)-based approaches for denoising images acquired with lower doses, shorter acquisition times, or both. Objective evaluation of these approaches is essential for clinical application. DL-based approaches for denoising nuclear-medicine images have typically been evaluated using fidelity-based figures of merit (FoMs) such as RMSE and SSIM. However, these images are acquired for clinical tasks and thus should be evaluated based on their performance in these tasks. Our objectives were to (1) investigate whether evaluation with these FoMs is consistent with objective clinical-task-based evaluation; (2) provide a theoretical analysis for determining the impact of denoising on signal-detection tasks; (3) demonstrate the utility of virtual clinical trials (VCTs) to evaluate DL-based methods. A VCT to evaluate a DL-based method for denoising myocardial perfusion SPECT (MPS) images was conducted. The impact of DL-based denoising was evaluated using fidelity-based FoMs and AUC, which quantified performance on detecting perfusion defects in MPS images as obtained using a model observer with anthropomorphic channels. Based on fidelity-based FoMs, denoising using the considered DL-based method led to significantly superior performance. However, based on ROC analysis, denoising did not improve, and in fact, often degraded detection-task performance. The results motivate the need for objective task-based evaluation of DL-based denoising approaches. Further, this study shows how VCTs provide a mechanism to conduct such evaluations using VCTs. Finally, our theoretical treatment reveals insights into the reasons for the limited performance of the denoising approach.
Face Anti-Spoofing (FAS) is recently studied under the continual learning setting, where the FAS models are expected to evolve after encountering the data from new domains. However, existing methods need extra replay buffers to store previous data for rehearsal, which becomes infeasible when previous data is unavailable because of privacy issues. In this paper, we propose the first rehearsal-free method for Domain Continual Learning (DCL) of FAS, which deals with catastrophic forgetting and unseen domain generalization problems simultaneously. For better generalization to unseen domains, we design the Dynamic Central Difference Convolutional Adapter (DCDCA) to adapt Vision Transformer (ViT) models during the continual learning sessions. To alleviate the forgetting of previous domains without using previous data, we propose the Proxy Prototype Contrastive Regularization (PPCR) to constrain the continual learning with previous domain knowledge from the proxy prototypes. Simulate practical DCL scenarios, we devise two new protocols which evaluate both generalization and anti-forgetting performance. Extensive experimental results show that our proposed method can improve the generalization performance in unseen domains and alleviate the catastrophic forgetting of the previous knowledge. The codes and protocols will be released soon.
Remote photoplethysmography (rPPG) technology has drawn increasing attention in recent years. It can extract Blood Volume Pulse (BVP) from facial videos, making many applications like health monitoring and emotional analysis more accessible. However, as the BVP signal is easily affected by environmental changes, existing methods struggle to generalize well for unseen domains. In this paper, we systematically address the domain shift problem in the rPPG measurement task. We show that most domain generalization methods do not work well in this problem, as domain labels are ambiguous in complicated environmental changes. In light of this, we propose a domain-label-free approach called NEuron STructure modeling (NEST). NEST improves the generalization capacity by maximizing the coverage of feature space during training, which reduces the chance for under-optimized feature activation during inference. Besides, NEST can also enrich and enhance domain invariant features across multi-domain. We create and benchmark a large-scale domain generalization protocol for the rPPG measurement task. Extensive experiments show that our approach outperforms the state-of-the-art methods on both cross-dataset and intra-dataset settings.
Deep-learning (DL)-based methods have shown significant promise in denoising myocardial perfusion SPECT images acquired at low dose. For clinical application of these methods, evaluation on clinical tasks is crucial. Typically, these methods are designed to minimize some fidelity-based criterion between the predicted denoised image and some reference normal-dose image. However, while promising, studies have shown that these methods may have limited impact on the performance of clinical tasks in SPECT. To address this issue, we use concepts from the literature on model observers and our understanding of the human visual system to propose a DL-based denoising approach designed to preserve observer-related information for detection tasks. The proposed method was objectively evaluated on the task of detecting perfusion defect in myocardial perfusion SPECT images using a retrospective study with anonymized clinical data. Our results demonstrate that the proposed method yields improved performance on this detection task compared to using low-dose images. The results show that by preserving task-specific information, DL may provide a mechanism to improve observer performance in low-dose myocardial perfusion SPECT.
The goal of Few-Shot Continual Learning (FSCL) is to incrementally learn novel tasks with limited labeled samples and preserve previous capabilities simultaneously, while current FSCL methods are all for the class-incremental purpose. Moreover, the evaluation of FSCL solutions is only the cumulative performance of all encountered tasks, but there is no work on exploring the domain generalization ability. Domain generalization is a challenging yet practical task that aims to generalize beyond training domains. In this paper, we set up a Generalized FSCL (GFSCL) protocol involving both class- and domain-incremental situations together with the domain generalization assessment. Firstly, two benchmark datasets and protocols are newly arranged, and detailed baselines are provided for this unexplored configuration. We find that common continual learning methods have poor generalization ability on unseen domains and cannot better cope with the catastrophic forgetting issue in cross-incremental tasks. In this way, we further propose a rehearsal-free framework based on Vision Transformer (ViT) named Contrastive Mixture of Adapters (CMoA). Due to different optimization targets of class increment and domain increment, the CMoA contains two parts: (1) For the class-incremental issue, the Mixture of Adapters (MoA) module is incorporated into ViT, then cosine similarity regularization and the dynamic weighting are designed to make each adapter learn specific knowledge and concentrate on particular classes. (2) For the domain-related issues and domain-invariant representation learning, we alleviate the inner-class variation by prototype-calibrated contrastive learning. The codes and protocols are available at https://github.com/yawencui/CMoA.