Rutgers University
Abstract:Knowledge editing (KE) provides a scalable approach for updating factual knowledge in large language models without full retraining. While previous studies have demonstrated effectiveness in general domains and medical QA tasks, little attention has been paid to KE in multimodal medical scenarios. Unlike text-only settings, medical KE demands integrating updated knowledge with visual reasoning to support safe and interpretable clinical decisions. To address this gap, we propose MultiMedEdit, the first benchmark tailored to evaluating KE in clinical multimodal tasks. Our framework spans both understanding and reasoning task types, defines a three-dimensional metric suite (reliability, generality, and locality), and supports cross-paradigm comparisons across general and domain-specific models. We conduct extensive experiments under single-editing and lifelong-editing settings. Results suggest that current methods struggle with generalization and long-tail reasoning, particularly in complex clinical workflows. We further present an efficiency analysis (e.g., edit latency, memory footprint), revealing practical trade-offs in real-world deployment across KE paradigms. Overall, MultiMedEdit not only reveals the limitations of current approaches but also provides a solid foundation for developing clinically robust knowledge editing techniques in the future.
Abstract:Objective: Large Language Models (LLMs) demonstrate significant capabilities in medical text understanding and generation. However, their diagnostic reliability in complex clinical scenarios remains limited. This study aims to enhance LLMs' diagnostic accuracy and clinical reasoning ability. Method: We propose an Etiology-Aware Attention Steering Framework to integrate structured clinical reasoning into LLM-based diagnosis. Specifically, we first construct Clinical Reasoning Scaffolding (CRS) based on authoritative clinical guidelines for three representative acute abdominal emergencies: acute appendicitis, acute pancreatitis, and acute cholecystitis. Next, we develop the Etiology-Aware Head Identification algorithm to pinpoint attention heads crucial for the model's etiology reasoning. To ensure reliable clinical reasoning alignment, we introduce the Reasoning-Guided Parameter-Efficient Fine-tuning that embeds etiological reasoning cues into input representations and steers the selected Etiology-Aware Heads toward critical information through a Reasoning-Guided Loss function. Result: On the Consistent Diagnosis Cohort, our framework improves average diagnostic accuracy by 15.65% and boosts the average Reasoning Focus Score by 31.6% over baselines. External validation on the Discrepant Diagnosis Cohort further confirms its effectiveness in enhancing diagnostic accuracy. Further assessments via Reasoning Attention Frequency indicate that our models exhibit enhanced reliability when faced with real-world complex scenarios. Conclusion: This study presents a practical and effective approach to enhance clinical reasoning in LLM-based diagnosis. By aligning model attention with structured CRS, the proposed framework offers a promising paradigm for building more interpretable and reliable AI diagnostic systems in complex clinical settings.
Abstract:Multimodal information retrieval (MIR) faces inherent challenges due to the heterogeneity of data sources and the complexity of cross-modal alignment. While previous studies have identified modal gaps in feature spaces, a systematic approach to address these challenges remains unexplored. In this work, we introduce UNITE, a universal framework that tackles these challenges through two critical yet underexplored aspects: data curation and modality-aware training configurations. Our work provides the first comprehensive analysis of how modality-specific data properties influence downstream task performance across diverse scenarios. Moreover, we propose Modal-Aware Masked Contrastive Learning (MAMCL) to mitigate the competitive relationships among the instances of different modalities. Our framework achieves state-of-the-art results on multiple multimodal retrieval benchmarks, outperforming existing methods by notable margins. Through extensive experiments, we demonstrate that strategic modality curation and tailored training protocols are pivotal for robust cross-modal representation learning. This work not only advances MIR performance but also provides a foundational blueprint for future research in multimodal systems. Our project is available at https://friedrichor.github.io/projects/UNITE.
Abstract:Videos are unique in their integration of temporal elements, including camera, scene, action, and attribute, along with their dynamic relationships over time. However, existing benchmarks for video understanding often treat these properties separately or narrowly focus on specific aspects, overlooking the holistic nature of video content. To address this, we introduce TUNA, a temporal-oriented benchmark for fine-grained understanding on dense dynamic videos, with two complementary tasks: captioning and QA. Our TUNA features diverse video scenarios and dynamics, assisted by interpretable and robust evaluation criteria. We evaluate several leading models on our benchmark, providing fine-grained performance assessments across various dimensions. This evaluation reveals key challenges in video temporal understanding, such as limited action description, inadequate multi-subject understanding, and insensitivity to camera motion, offering valuable insights for improving video understanding models. The data and code are available at https://friedrichor.github.io/projects/TUNA.
Abstract:Integrating Large Language Models with symbolic planners is a promising direction for obtaining verifiable and grounded plans compared to planning in natural language, with recent works extending this idea to visual domains using Vision-Language Models (VLMs). However, rigorous comparison between VLM-grounded symbolic approaches and methods that plan directly with a VLM has been hindered by a lack of common environments, evaluation protocols and model coverage. We introduce ViPlan, the first open-source benchmark for Visual Planning with symbolic predicates and VLMs. ViPlan features a series of increasingly challenging tasks in two domains: a visual variant of the classic Blocksworld planning problem and a simulated household robotics environment. We benchmark nine open-source VLM families across multiple sizes, along with selected closed models, evaluating both VLM-grounded symbolic planning and using the models directly to propose actions. We find symbolic planning to outperform direct VLM planning in Blocksworld, where accurate image grounding is crucial, whereas the opposite is true in the household robotics tasks, where commonsense knowledge and the ability to recover from errors are beneficial. Finally, we show that across most models and methods, there is no significant benefit to using Chain-of-Thought prompting, suggesting that current VLMs still struggle with visual reasoning.
Abstract:Clinical evidence, derived from rigorous research and data analysis, provides healthcare professionals with reliable scientific foundations for informed decision-making. Integrating clinical evidence into real-time practice is challenging due to the enormous workload, complex professional processes, and time constraints. This highlights the need for tools that automate evidence synthesis to support more efficient and accurate decision making in clinical settings. This study introduces Quicker, an evidence-based clinical decision support system powered by large language models (LLMs), designed to automate evidence synthesis and generate clinical recommendations modeled after standard clinical guideline development processes. Quicker implements a fully automated chain that covers all phases, from questions to clinical recommendations, and further enables customized decision-making through integrated tools and interactive user interfaces. To evaluate Quicker's capabilities, we developed the Q2CRBench-3 benchmark dataset, based on clinical guideline development records for three different diseases. Experimental results highlighted Quicker's strong performance, with fine-grained question decomposition tailored to user preferences, retrieval sensitivities comparable to human experts, and literature screening performance approaching comprehensive inclusion of relevant studies. In addition, Quicker-assisted evidence assessment effectively supported human reviewers, while Quicker's recommendations were more comprehensive and logically coherent than those of clinicians. In system-level testing, collaboration between a single reviewer and Quicker reduced the time required for recommendation development to 20-40 minutes. In general, our findings affirm the potential of Quicker to help physicians make quicker and more reliable evidence-based clinical decisions.
Abstract:We present Seedream 3.0, a high-performance Chinese-English bilingual image generation foundation model. We develop several technical improvements to address existing challenges in Seedream 2.0, including alignment with complicated prompts, fine-grained typography generation, suboptimal visual aesthetics and fidelity, and limited image resolutions. Specifically, the advancements of Seedream 3.0 stem from improvements across the entire pipeline, from data construction to model deployment. At the data stratum, we double the dataset using a defect-aware training paradigm and a dual-axis collaborative data-sampling framework. Furthermore, we adopt several effective techniques such as mixed-resolution training, cross-modality RoPE, representation alignment loss, and resolution-aware timestep sampling in the pre-training phase. During the post-training stage, we utilize diversified aesthetic captions in SFT, and a VLM-based reward model with scaling, thereby achieving outputs that well align with human preferences. Furthermore, Seedream 3.0 pioneers a novel acceleration paradigm. By employing consistent noise expectation and importance-aware timestep sampling, we achieve a 4 to 8 times speedup while maintaining image quality. Seedream 3.0 demonstrates significant improvements over Seedream 2.0: it enhances overall capabilities, in particular for text-rendering in complicated Chinese characters which is important to professional typography generation. In addition, it provides native high-resolution output (up to 2K), allowing it to generate images with high visual quality.
Abstract:The rapid advancement of large language models (LLMs) has brought significant benefits to various domains while introducing substantial risks. Despite being fine-tuned through reinforcement learning, LLMs lack the capability to discern malicious content, limiting their defense against jailbreak. To address these safety concerns, we propose a feature-aware method for harmful response rejection (FMM), which detects the presence of malicious features within the model's feature space and adaptively adjusts the model's rejection mechanism. By employing a simple discriminator, we detect potential malicious traits during the decoding phase. Upon detecting features indicative of toxic tokens, FMM regenerates the current token. By employing activation patching, an additional rejection vector is incorporated during the subsequent token generation, steering the model towards a refusal response. Experimental results demonstrate the effectiveness of our approach across multiple language models and diverse attack techniques, while crucially maintaining the models' standard generation capabilities.
Abstract:The reproduction of state-of-the-art multimodal LLM pre-training faces barriers at every stage of the pipeline, including high-quality data filtering, multimodal data mixture strategies, sequence packing techniques, and training frameworks. We introduce Open-Qwen2VL, a fully open-source 2B-parameter Multimodal Large Language Model pre-trained efficiently on 29M image-text pairs using only 220 A100-40G GPU hours. Our approach employs low-to-high dynamic image resolution and multimodal sequence packing to significantly enhance pre-training efficiency. The training dataset was carefully curated using both MLLM-based filtering techniques (e.g., MLM-Filter) and conventional CLIP-based filtering methods, substantially improving data quality and training efficiency. The Open-Qwen2VL pre-training is conducted on academic level 8xA100-40G GPUs at UCSB on 5B packed multimodal tokens, which is 0.36% of 1.4T multimodal pre-training tokens of Qwen2-VL. The final instruction-tuned Open-Qwen2VL outperforms partially-open state-of-the-art MLLM Qwen2-VL-2B on various multimodal benchmarks of MMBench, SEEDBench, MMstar, and MathVista, indicating the remarkable training efficiency of Open-Qwen2VL. We open-source all aspects of our work, including compute-efficient and data-efficient training details, data filtering methods, sequence packing scripts, pre-training data in WebDataset format, FSDP-based training codebase, and both base and instruction-tuned model checkpoints. We redefine "fully open" for multimodal LLMs as the complete release of: 1) the training codebase, 2) detailed data filtering techniques, and 3) all pre-training and supervised fine-tuning data used to develop the model.
Abstract:The rapid and unrestrained advancement of generative artificial intelligence (AI) presents a double-edged sword: while enabling unprecedented creativity, it also facilitates the generation of highly convincing deceptive content, undermining societal trust. As image generation techniques become increasingly sophisticated, detecting synthetic images is no longer just a binary task: it necessitates interpretable, context-aware methodologies that enhance trustworthiness and transparency. However, existing detection models primarily focus on classification, offering limited explanatory insights into image authenticity. In this work, we propose FakeScope, an expert multimodal model (LMM) tailored for AI-generated image forensics, which not only identifies AI-synthetic images with high accuracy but also provides rich, interpretable, and query-driven forensic insights. We first construct FakeChain dataset that contains linguistic authenticity reasoning based on visual trace evidence, developed through a novel human-machine collaborative framework. Building upon it, we further present FakeInstruct, the largest multimodal instruction tuning dataset containing 2 million visual instructions tailored to enhance forensic awareness in LMMs. FakeScope achieves state-of-the-art performance in both closed-ended and open-ended forensic scenarios. It can distinguish synthetic images with high accuracy while offering coherent and insightful explanations, free-form discussions on fine-grained forgery attributes, and actionable enhancement strategies. Notably, despite being trained exclusively on qualitative hard labels, FakeScope demonstrates remarkable zero-shot quantitative capability on detection, enabled by our proposed token-based probability estimation strategy. Furthermore, FakeScope exhibits strong generalization and in-the-wild ability, ensuring its applicability in real-world scenarios.