Pathologist-like explainable AI for interpretable Gleason grading in prostate cancer

The aggressiveness of prostate cancer, the most common cancer in men worldwide, is primarily assessed based on histopathological data using the Gleason scoring system. While artificial intelligence (AI) has shown promise in accurately predicting Gleason scores, these predictions often lack inherent explainability, potentially leading to distrust in human-machine interactions. To address this issue, we introduce a novel dataset of 1,015 tissue microarray core images, annotated by an international group of 54 pathologists. The annotations provide detailed localized pattern descriptions for Gleason grading in line with international guidelines. Utilizing this dataset, we develop an inherently explainable AI system based on a U-Net architecture that provides predictions leveraging pathologists' terminology. This approach circumvents post-hoc explainability methods while maintaining or exceeding the performance of methods trained directly for Gleason pattern segmentation (Dice score: 0.713 $\pm$ 0.003 trained on explanations vs. 0.691 $\pm$ 0.010 trained on Gleason patterns). By employing soft labels during training, we capture the intrinsic uncertainty in the data, yielding strong results in Gleason pattern segmentation even in the context of high interobserver variability. With the release of this dataset, we aim to encourage further research into segmentation in medical tasks with high levels of subjectivity and to advance the understanding of pathologists' reasoning processes.

GyroCopter: Differential Bearing Measuring Trajectory Planner for Tracking and Localizing Radio Frequency Sources

Autonomous aerial vehicles can provide efficient and effective solutions for radio frequency (RF) source tracking and localizing problems with applications ranging from wildlife conservation to search and rescue operations. Existing lightweight, low-cost, bearing measurements-based methods with a single antenna-receiver sensor system configurations necessitate in situ rotations, leading to substantial measurement acquisition times restricting searchable areas and number of measurements. We propose a GyroCopter for the task. Our approach plans the trajectory of a multi-rotor unmanned aerial vehicle (UAV) whilst utilizing UAV flight dynamics to execute a constant gyration motion to derive "pseudo-bearing" measurements to track RF sources. The gyration-based pseudo-bearing approach: i) significantly reduces the limitations associated with in situ rotation bearing; while ii) capitalizing on the simplicity, affordability, and lightweight nature of signal strength measurement acquisition hardware to estimate bearings. This method distinguishes itself from other pseudo-bearing approaches by eliminating the need for additional hardware to maintain simplicity, lightweightness and cost-effectiveness. To validate our approach, we derived the optimal rotation speed and conducted extensive simulations and field missions with our GyroCopter to track and localize multiple RF sources. The results confirm the effectiveness of our method, highlighting its potential as a practical and rapid solution for RF source localization tasks.

GARField: Addressing the visual Sim-to-Real gap in garment manipulation with mesh-attached radiance fields

While humans intuitively manipulate garments and other textiles items swiftly and accurately, it is a significant challenge for robots. A factor crucial to the human performance is the ability to imagine, a priori, the intended result of the manipulation intents and hence develop predictions on the garment pose. This allows us to plan from highly obstructed states, adapt our plans as we collect more information and react swiftly to unforeseen circumstances. Robots, on the other hand, struggle to establish such intuitions and form tight links between plans and observations. This can be attributed in part to the high cost of obtaining densely labelled data for textile manipulation, both in quality and quantity. The problem of data collection is a long standing issue in data-based approaches to garment manipulation. Currently, the generation of high quality and labelled garment manipulation data is mainly attempted through advanced data capture procedures that create simplified state estimations from real-world observations. In this work, however, we propose to generate real-world observations from given object states. To achieve this, we present GARField (Garment Attached Radiance Field) a differentiable rendering architecture allowing data generation from simulated states stored as triangle meshes. Code will be available on https://ddonatien.github.io/garfield-website/

Attention-Based Beamformer For Multi-Channel Speech Enhancement

Minimum Variance Distortionless Response (MVDR) is a classical adaptive beamformer that theoretically ensures the distortionless transmission of signals in the target direction. Its performance in noise reduction actually depends on the accuracy of the noise spatial covariance matrix (SCM) estimate. Although recent deep learning has shown remarkable performance in multi-channel speech enhancement, the property of distortionless response still makes MVDR highly popular in real applications. In this paper, we propose an attention-based mechanism to calculate the speech and noise SCM and then apply MVDR to obtain the enhanced speech. Moreover, a deep learning architecture using the inplace convolution operator and frequency-independent LSTM has proven effective in facilitating SCM estimation. The model is optimized in an end-to-end manner. Experimental results indicate that the proposed method is extremely effective in tracking moving or stationary speakers under non-causal and causal conditions, outperforming other baselines. It is worth mentioning that our model has only 0.35 million parameters, making it easy to be deployed on edge devices.

Unrolling Plug-and-Play Gradient Graph Laplacian Regularizer for Image Restoration

Generic deep learning (DL) networks for image restoration like denoising and interpolation lack mathematical interpretability, require voluminous training data to tune a large parameter set, and are fragile during covariance shift. To address these shortcomings, for a general linear image formation model, we first formulate a convex optimization problem with a new graph smoothness prior called gradient graph Laplacian regularizer (GGLR) that promotes piecewise planar (PWP) signal reconstruction. To solve the posed problem, we introduce a variable number of auxiliary variables to create a family of Plug-and-Play (PnP) ADMM algorithms and unroll them into variable-complexity feed-forward networks, amenable to parameter tuning via back-propagation. More complex unrolled networks require more labeled data to train more parameters, but have better potential performance. Experimental results show that our unrolled networks perform competitively to generic DL networks in image restoration quality while using a small fraction of parameters, and demonstrate improved robustness to covariance shift.

MULAN: A Multi Layer Annotated Dataset for Controllable Text-to-Image Generation

Text-to-image generation has achieved astonishing results, yet precise spatial controllability and prompt fidelity remain highly challenging. This limitation is typically addressed through cumbersome prompt engineering, scene layout conditioning, or image editing techniques which often require hand drawn masks. Nonetheless, pre-existing works struggle to take advantage of the natural instance-level compositionality of scenes due to the typically flat nature of rasterized RGB output images. Towards adressing this challenge, we introduce MuLAn: a novel dataset comprising over 44K MUlti-Layer ANnotations of RGB images as multilayer, instance-wise RGBA decompositions, and over 100K instance images. To build MuLAn, we developed a training free pipeline which decomposes a monocular RGB image into a stack of RGBA layers comprising of background and isolated instances. We achieve this through the use of pretrained general-purpose models, and by developing three modules: image decomposition for instance discovery and extraction, instance completion to reconstruct occluded areas, and image re-assembly. We use our pipeline to create MuLAn-COCO and MuLAn-LAION datasets, which contain a variety of image decompositions in terms of style, composition and complexity. With MuLAn, we provide the first photorealistic resource providing instance decomposition and occlusion information for high quality images, opening up new avenues for text-to-image generative AI research. With this, we aim to encourage the development of novel generation and editing technology, in particular layer-wise solutions. MuLAn data resources are available at https://MuLAn-dataset.github.io/.

Fusion Dynamical Systems with Machine Learning in Imitation Learning: A Comprehensive Overview

Imitation Learning (IL), also referred to as Learning from Demonstration (LfD), holds significant promise for capturing expert motor skills through efficient imitation, facilitating adept navigation of complex scenarios. A persistent challenge in IL lies in extending generalization from historical demonstrations, enabling the acquisition of new skills without re-teaching. Dynamical system-based IL (DSIL) emerges as a significant subset of IL methodologies, offering the ability to learn trajectories via movement primitives and policy learning based on experiential abstraction. This paper emphasizes the fusion of theoretical paradigms, integrating control theory principles inherent in dynamical systems into IL. This integration notably enhances robustness, adaptability, and convergence in the face of novel scenarios. This survey aims to present a comprehensive overview of DSIL methods, spanning from classical approaches to recent advanced approaches. We categorize DSIL into autonomous dynamical systems and non-autonomous dynamical systems, surveying traditional IL methods with low-dimensional input and advanced deep IL methods with high-dimensional input. Additionally, we present and analyze three main stability methods for IL: Lyapunov stability, contraction theory, and diffeomorphism mapping. Our exploration also extends to popular policy improvement methods for DSIL, encompassing reinforcement learning, deep reinforcement learning, and evolutionary strategies.

Accelerating Diffusion Sampling with Optimized Time Steps

Diffusion probabilistic models (DPMs) have shown remarkable performance in high-resolution image synthesis, but their sampling efficiency is still to be desired due to the typically large number of sampling steps. Recent advancements in high-order numerical ODE solvers for DPMs have enabled the generation of high-quality images with much fewer sampling steps. While this is a significant development, most sampling methods still employ uniform time steps, which is not optimal when using a small number of steps. To address this issue, we propose a general framework for designing an optimization problem that seeks more appropriate time steps for a specific numerical ODE solver for DPMs. This optimization problem aims to minimize the distance between the ground-truth solution to the ODE and an approximate solution corresponding to the numerical solver. It can be efficiently solved using the constrained trust region method, taking less than $15$ seconds. Our extensive experiments on both unconditional and conditional sampling using pixel- and latent-space DPMs demonstrate that, when combined with the state-of-the-art sampling method UniPC, our optimized time steps significantly improve image generation performance in terms of FID scores for datasets such as CIFAR-10 and ImageNet, compared to using uniform time steps.

TAnet: A New Temporal Attention Network for EEG-based Auditory Spatial Attention Decoding with a Short Decision Window

Auditory spatial attention detection (ASAD) is used to determine the direction of a listener's attention to a speaker by analyzing her/his electroencephalographic (EEG) signals. This study aimed to further improve the performance of ASAD with a short decision window (i.e., <1 s) rather than with long decision windows in previous studies. An end-to-end temporal attention network (i.e., TAnet) was introduced in this work. TAnet employs a multi-head attention (MHA) mechanism, which can more effectively capture the interactions among time steps in collected EEG signals and efficiently assign corresponding weights to those EEG time steps. Experiments demonstrated that, compared with the CNN-based method and recent ASAD methods, TAnet provided improved decoding performance in the KUL dataset, with decoding accuracies of 92.4% (decision window 0.1 s), 94.9% (0.25 s), 95.1% (0.3 s), 95.4% (0.4 s), and 95.5% (0.5 s) with short decision windows (i.e., <1 s). As a new ASAD model with a short decision window, TAnet can potentially facilitate the design of EEG-controlled intelligent hearing aids and sound recognition systems.

Distributed Multi-Object Tracking Under Limited Field of View Heterogeneous Sensors with Density Clustering

We consider the problem of tracking multiple, unknown, and time-varying numbers of objects using a distributed network of heterogeneous sensors. In an effort to derive a formulation for practical settings, we consider limited and unknown sensor field-of-views (FoVs), sensors with limited local computational resources and communication channel capacity. The resulting distributed multi-object tracking algorithm involves solving an NP-hard multidimensional assignment problem either optimally for small-size problems or sub-optimally for general practical problems. For general problems, we propose an efficient distributed multi-object tracking algorithm that performs track-to-track fusion using a clustering-based analysis of the state space transformed into a density space to mitigate the complexity of the assignment problem. The proposed algorithm can more efficiently group local track estimates for fusion than existing approaches. To ensure we achieve globally consistent identities for tracks across a network of nodes as objects move between FoVs, we develop a graph-based algorithm to achieve label consensus and minimise track segmentation. Numerical experiments with a synthetic and a real-world trajectory dataset demonstrate that our proposed method is significantly more computationally efficient than state-of-the-art solutions, achieving similar tracking accuracy and bandwidth requirements but with improved label consistency.