WorldMark: A Unified Benchmark Suite for Interactive Video World Models

Interactive video generation models such as Genie, YUME, HY-World, and Matrix-Game are advancing rapidly, yet every model is evaluated on its own benchmark with private scenes and trajectories, making fair cross-model comparison impossible. Existing public benchmarks offer useful metrics such as trajectory error, aesthetic scores, and VLM-based judgments, but none supplies the standardized test conditions -- identical scenes, identical action sequences, and a unified control interface -- needed to make those metrics comparable across models with heterogeneous inputs. We introduce WorldMark, the first benchmark that provides such a common playing field for interactive Image-to-Video world models. WorldMark contributes: (1) a unified action-mapping layer that translates a shared WASD-style action vocabulary into each model's native control format, enabling apples-to-apples comparison across six major models on identical scenes and trajectories; (2) a hierarchical test suite of 500 evaluation cases covering first- and third-person viewpoints, photorealistic and stylized scenes, and three difficulty tiers from Easy to Hard spanning 20-60s; and (3) a modular evaluation toolkit for Visual Quality, Control Alignment, and World Consistency, designed so that researchers can reuse our standardized inputs while plugging in their own metrics as the field evolves. We will release all data, evaluation code, and model outputs to facilitate future research. Beyond offline metrics, we launch World Model Arena (warena.ai), an online platform where anyone can pit leading world models against each other in side-by-side battles and watch the live leaderboard.

Cycle-Consistent Search: Question Reconstructability as a Proxy Reward for Search Agent Training

Reinforcement Learning (RL) has shown strong potential for optimizing search agents in complex information retrieval tasks. However, existing approaches predominantly rely on gold supervision, such as ground-truth answers, which is difficult to scale. To address this limitation, we propose Cycle-Consistent Search (CCS), a gold-supervision-free framework for training search agents, inspired by cycle-consistency techniques from unsupervised machine translation and image-to-image translation. Our key hypothesis is that an optimal search trajectory, unlike insufficient or irrelevant ones, serves as a lossless encoding of the question's intent. Consequently, a high-quality trajectory should preserve the information required to accurately reconstruct the original question, thereby inducing a reward signal for policy optimization. However, naive cycle-consistency objectives are vulnerable to information leakage, as reconstruction may rely on superficial lexical cues rather than the underlying search process. To reduce this effect, we apply information bottlenecks, including exclusion of the final response and named entity recognition (NER) masking of search queries. These constraints force reconstruction to rely on retrieved observations together with the structural scaffold, ensuring that the resulting reward signal reflects informational adequacy rather than linguistic redundancy. Experiments on question-answering benchmarks show that CCS achieves performance comparable to supervised baselines while outperforming prior methods that do not rely on gold supervision. These results suggest that CCS provides a scalable training paradigm for training search agents in settings where gold supervision is unavailable.

Harmonizing MR Images Across 100+ Scanners: Multi-site Validation with Traveling Subjects and Real-world Protocols

Reliable harmonization of heterogeneous magnetic resonance~(MR) image datasets, especially those acquired in pragmatic clinical trials, is critical to advance multi-center neuroimaging studies and translational machine learning in healthcare. We present an enhanced and rigorously validated version of the HACA3 harmonization algorithm, which we refer to as HACA3$^+$, incorporating key methodological enhancements: (1)~an improved artifact encoder to better isolate and mitigate image artifacts, (2)~background and foreground-sensitive attention mechanisms to increase harmonization specificity, and (3)~extensive training using data spanning 100+ scanners from 64 independent sites, providing a broader diversity of scanners than other harmonization methods. Our study focuses on four commonly acquired MR image contrasts (T1-weighted, T2-weighted, proton density, \& fluid-attenuated inversion recovery), reflecting realistic clinical protocols. We perform inter-site harmonization experiments using traveling subjects to assess the generalization and robustness of the harmonization model. We compare the results of the publicly available version of HACA3 and our implementation, HACA3$^+$. Downstream relevance is further established through whole brain segmentation and image imputation. Finally, we justify each enhancement through an ablation experiment. Pre-trained weights and code for HACA3$^+$ are made publicly available at https://github.com/shays15/haca3-plus.

STAND: Semantic Anchoring Constraint with Dual-Granularity Disambiguation for Remote Sensing Image Change Captioning

Remote sensing image change captioning (RSICC) aims to describe the difference between two remote sensing images. While recent methods have explored video modeling, they largely overlook the inherent ambiguities in viewpoint, scale, and prior knowledge, lacking effective constraints on the encoder. In this paper, we present STAND, a Semantic Anchoring Constraint with Dual-Granularity Disambiguation for RSICC, to progressively resolve these ambiguities. Specifically, to establish a reliable feature foundation, we first introduce an interpretable constraint to regularize temporal representations. Operating on these purified features, a dual-granularity disambiguation module resolves spatial uncertainties by coupling macro-level global context aggregation for viewpoint confusion with micro-level frequency-refocused attention for small-object scale enhancement. Ultimately, to translate these visually disambiguated features into precise text, a semantic concept anchoring module leverages language categorical priors to tackle knowledge ambiguity during decoding. Extensive experiments verify the superiority of STAND and its effectiveness in addressing ambiguities.

Unsupervised Learning of Inter-Object Relationships via Group Homomorphism

While current deep learning models achieve high performance by learning statistical correlations from vast datasets,which stands in stark contrast to human learning. They lack the flexibility of humans-particularly preverbal infants-to autonomously acquire the underlying structure of the world from limited experience and adapt to novel situations. In this study, we propose an unsupervised representation learning method based on a hierarchical relationship in group operations, rather than statistical independence, aiming to build a computational model of the cognitive development of infants. The proposed model features an integrated architecture that simultaneously performs object segmentation and the extraction of motion laws from dynamic image sequences. By introducing the Homomorphism from algebra as a structural constraint within a neural network, the model structurally separates pixel-level changes into meaningful, decomposed transformation components, such as translation and deformation. Using interaction scenes (chasing and evading tasks) based on developmental science findings, we experimentally demonstrate that the model can segment multiple objects into individual slots without any ground-truth labels. Furthermore, we confirmed that relative movements between objects, such as approaching or receding, are accurately mapped and structured into a one-dimensional additive latent space. These results suggest that by introducing algebraic geometric constraints rather than relying solely on statistical correlation learning, physically interpretable "disentangled representations" can be acquired. This study contributes to the understanding of the process by which infants internalize environmental laws as structures and provides a new perspective for constructing artificial systems with developmental intelligence.

Wan-Image: Pushing the Boundaries of Generative Visual Intelligence

We present Wan-Image, a unified visual generation system explicitly engineered to paradigm-shift image generation models from casual synthesizers into professional-grade productivity tools. While contemporary diffusion models excel at aesthetic generation, they frequently encounter critical bottlenecks in rigorous design workflows that demand absolute controllability, complex typography rendering, and strict identity preservation. To address these challenges, Wan-Image features a natively unified multi-modal architecture by synergizing the cognitive capabilities of large language models with the high-fidelity pixel synthesis of diffusion transformers, which seamlessly translates highly nuanced user intents into precise visual outputs. It is fundamentally powered by large-scale multi-modal data scaling, a systematic fine-grained annotation engine, and curated reinforcement learning data to surpass basic instruction following and unlock expert-level professional capabilities. These include ultra-long complex text rendering, hyper-diverse portrait generation, palette-guided generation, multi-subject identity preservation, coherent sequential visual generation, precise multi-modal interactive editing, native alpha-channel generation, and high-efficiency 4K synthesis. Across diverse human evaluations, Wan-Image exceeds Seedream 5.0 Lite and GPT Image 1.5 in overall performance, reaching parity with Nano Banana Pro in challenging tasks. Ultimately, Wan-Image revolutionizes visual content creation across e-commerce, entertainment, education, and personal productivity, redefining the boundaries of professional visual synthesis.

VS-DDPM: Efficient Low-Cost Diffusion Model for Medical Modality Translation

Diffusion models produce high-quality synthetic data but suffer from slow inference. We propose 3D Variable-Step Denoising Diffusion Probabilistic Model (VS-DDPM) a framework engineered to maintain generative quality while accelerating inference by several factors. We tested our approach on four tasks (missing MRI, tumor removal, MRI-to-sCT, and CBCT-to-sCT) within the BraTS2025 and SynthRAD2025 challenges. Designed for high efficiency under hardware and time constrains imposed by both challenges. VS-DDPM achieved state-of-the-art (SOTA) performance in missing MRI synthesis, yielding Dice scores of 0.80, 0.83, and 0.88 for the enhancing tumor, tumor core, and whole tumor regions, respectively, alongside a structural similarity index (SSIM) of 0.95. For MRI tumor removal, the model attained a root mean squared error (RMSE) of 0.053, a peak signal-to-noise ratio (PSNR) of 26.77, and an SSIM of 0.918. While the framework demonstrated competitive performance in MRI-to-sCT and CBCT-to-sCT tasks, it did not reach SOTA benchmarks, potentially due to sensitivities in data pre and post-processing pipelines or specific loss function configurations. These results demonstrate that VS-DDPM provides a robust and tunable solution for high-fidelity 3D medical image synthesis. The code is available in https://github.com/andre-fs-ferreira/SynthRAD_by_Faking_it.

Bridging MRI and PET physiology: Untangling complementarity through orthogonal representations

Multimodal imaging analysis often relies on joint latent representations, yet these approaches rarely define what information is shared versus modality-specific. Clarifying this distinction is clinically relevant, as it delineates the irreducible contribution of each modality and informs rational acquisition strategies. We propose a subspace decomposition framework that reframes multimodal fusion as a problem of orthogonal subspace separation rather than translation. We decompose Prostate-Specific Membrane Antigen (PSMA) PET uptake into an MRI-explainable physiological envelope and an orthogonal residual reflecting signal components not expressible within the MRI feature manifold. Using multiparametric MRI, we train an intensity-based, non-spatial implicit neural representation (INR) to map MRI feature vectors to PET uptake. We introduce a projection-based regularization using singular value decomposition to penalize residual components lying within the span of the MRI feature manifold. This enforces mathematical orthogonality between tissue-level physiological properties (structure, diffusion, perfusion) and intracellular PSMA expression. Tested on 13 prostate cancer patients, the model demonstrates that residual components spanned by MRI features are absorbed into the learned envelope, while the orthogonal residual is largest in tumour regions. This indicates that PSMA PET contains signal components not recoverable from MRI-derived physiological descriptors. The resulting decomposition provides a structured characterization of modality complementarity grounded in representation geometry rather than image translation.

REVEAL: Multimodal Vision-Language Alignment of Retinal Morphometry and Clinical Risks for Incident AD and Dementia Prediction

The retina provides a unique, noninvasive window into Alzheimer's disease (AD) and dementia, capturing early structural changes through morphometric features, while systemic and lifestyle risk factors reflect well-established contributors to disease susceptibility long before clinical symptom onset. However, current retinal analysis frameworks typically model imaging and risk factors separately, limiting their ability to capture joint multimodal patterns critical for early risk prediction. Moreover, existing methods rarely incorporate mechanisms to organize or align patients with similar retinal and clinical characteristics, constraining the learning of coherent cross-modal associations. To address these limitations, we introduce REVEAL (REtinal-risk Vision-Language Early Alzheimer's Learning), a framework that aligns color fundus photographs with individualized disease-specific risk profiles for predicting incident AD and dementia, on average 8 years before diagnosis (range: 1-11 years). Because real-world risk factors are structured questionnaire data, we translate them into clinically interpretable narratives compatible with pretrained vision-language models (VLMs). We further propose a group-aware contrastive learning (GACL) strategy that clusters patients with similar retinal morphometry and risk factors as positive pairs, strengthening multimodal alignment. This unified representation learning framework substantially outperforms state-of-the-art retinal imaging models paired with clinical text encoders, as well as general-purpose VLMs, demonstrating the value of jointly modeling retinal biomarkers and clinical risk factors. By providing a generalizable and noninvasive approach for early AD and dementia risk stratification, REVEAL has the potential to enable earlier intervention and improve preventive care at the population level.

Visual Instruction-Finetuned Language Model for Versatile Brain MR Image Tasks

LLMs have demonstrated remarkable capabilities in linguistic reasoning and are increasingly adept at vision-language tasks. The integration of image tokens into transformers has enabled direct visual input and output, advancing research from image-to-text descriptions to text-to-image generation. However, simple text-to-image generation holds limited clinical utility. In medical imaging, tasks such as image segmentation for localizing pathologies or image translation for reconstructing missing sequences have much greater clinical importance. Despite this, integrating these diverse, clinically relevant tasks within a single, versatile language model remains unexplored. Our method, LLaBIT (Large Language Model for Brain Image Translation), extends the visual reasoning of LLMs to these clinically meaningful tasks in the brain MRI domain. To mitigate the spatial information loss inherent in image tokenization, we incorporate a mechanism to reuse feature maps from the image encoder, minimizing data degradation. We also generate text data using LLMs with strict predefined instructions to augment limited image-text paired data in brain MRI. We comprehensively evaluated our method on five brain MRI datasets across four distinct tasks: report generation, visual question answering, image segmentation, and image translation. Our model not only demonstrated superior performance across all tasks but also outperformed specialized, task-specific models in direct comparisons, highlighting its efficacy and versatility