BioClinical ModernBERT: A State-of-the-Art Long-Context Encoder for Biomedical and Clinical NLP

Encoder-based transformer models are central to biomedical and clinical Natural Language Processing (NLP), as their bidirectional self-attention makes them well-suited for efficiently extracting structured information from unstructured text through discriminative tasks. However, encoders have seen slower development compared to decoder models, leading to limited domain adaptation in biomedical and clinical settings. We introduce BioClinical ModernBERT, a domain-adapted encoder that builds on the recent ModernBERT release, incorporating long-context processing and substantial improvements in speed and performance for biomedical and clinical NLP. BioClinical ModernBERT is developed through continued pretraining on the largest biomedical and clinical corpus to date, with over 53.5 billion tokens, and addresses a key limitation of prior clinical encoders by leveraging 20 datasets from diverse institutions, domains, and geographic regions, rather than relying on data from a single source. It outperforms existing biomedical and clinical encoders on four downstream tasks spanning a broad range of use cases. We release both base (150M parameters) and large (396M parameters) versions of BioClinical ModernBERT, along with training checkpoints to support further research.

Flick: Few Labels Text Classification using K-Aware Intermediate Learning in Multi-Task Low-Resource Languages

Training deep learning networks with minimal supervision has gained significant research attention due to its potential to reduce reliance on extensive labelled data. While self-training methods have proven effective in semi-supervised learning, they remain vulnerable to errors from noisy pseudo labels. Moreover, most recent approaches to the few-label classification problem are either designed for resource-rich languages such as English or involve complex cascading models that are prone to overfitting. To address the persistent challenge of few-label text classification in truly low-resource linguistic contexts, where existing methods often struggle with noisy pseudo-labels and domain adaptation, we propose Flick. Unlike prior methods that rely on generic multi-cluster pseudo-labelling or complex cascading architectures, Flick leverages the fundamental insight that distilling high-confidence pseudo-labels from a broader set of initial clusters can dramatically improve pseudo-label quality, particularly for linguistically diverse, low-resource settings. Flick introduces a novel pseudo-label refinement component, a departure from traditional pseudo-labelling strategies by identifying and leveraging top-performing pseudo-label clusters. This component specifically learns to distil highly reliable pseudo-labels from an initial broad set by focusing on single-cluster cohesion and leveraging an adaptive top-k selection mechanism. This targeted refinement process is crucial for mitigating the propagation of errors inherent in low-resource data, allowing for robust fine-tuning of pre-trained language models with only a handful of true labels. We demonstrate Flick's efficacy across 14 diverse datasets, encompassing challenging low-resource languages such as Arabic, Urdu, and Setswana, alongside English, showcasing its superior performance and adaptability.

Low-resource domain adaptation while minimizing energy and hardware resource consumption

Training Large Language Models (LLMs) is costly in terms of energy, hardware, and annotated data, often resulting in a positionality rooted in predominant cultures and values (Santy et al., 2023). Domain adaptation has emerged as a promising strategy to better align models with diverse cultural and value contexts (Hershcovich et al., 2022), but its computational cost remains a significant barrier, particularly for research groups lacking access to large-scale infrastructure. In this paper, we evaluate how the use of different numerical precision formats and data parallelization strategies impacts both training speed (as a proxy to energy and hardware consumption) and model accuracy, with the goal of facilitating domain adaptation in low-resource environments. Our findings are relevant to any setting where energy efficiency, accessibility, or limited hardware availability are key concerns.

Enhancing Human-Robot Collaboration: A Sim2Real Domain Adaptation Algorithm for Point Cloud Segmentation in Industrial Environments

The robust interpretation of 3D environments is crucial for human-robot collaboration (HRC) applications, where safety and operational efficiency are paramount. Semantic segmentation plays a key role in this context by enabling a precise and detailed understanding of the environment. Considering the intense data hunger for real-world industrial annotated data essential for effective semantic segmentation, this paper introduces a pioneering approach in the Sim2Real domain adaptation for semantic segmentation of 3D point cloud data, specifically tailored for HRC. Our focus is on developing a network that robustly transitions from simulated environments to real-world applications, thereby enhancing its practical utility and impact on a safe HRC. In this work, we propose a dual-stream network architecture (FUSION) combining Dynamic Graph Convolutional Neural Networks (DGCNN) and Convolutional Neural Networks (CNN) augmented with residual layers as a Sim2Real domain adaptation algorithm for an industrial environment. The proposed model was evaluated on real-world HRC setups and simulation industrial point clouds, it showed increased state-of-the-art performance, achieving a segmentation accuracy of 97.76%, and superior robustness compared to existing methods.

SRPL-SFDA: SAM-Guided Reliable Pseudo-Labels for Source-Free Domain Adaptation in Medical Image Segmentation

Domain Adaptation (DA) is crucial for robust deployment of medical image segmentation models when applied to new clinical centers with significant domain shifts. Source-Free Domain Adaptation (SFDA) is appealing as it can deal with privacy concerns and access constraints on source-domain data during adaptation to target-domain data. However, SFDA faces challenges such as insufficient supervision in the target domain with unlabeled images. In this work, we propose a Segment Anything Model (SAM)-guided Reliable Pseudo-Labels method for SFDA (SRPL-SFDA) with three key components: 1) Test-Time Tri-branch Intensity Enhancement (T3IE) that not only improves quality of raw pseudo-labels in the target domain, but also leads to SAM-compatible inputs with three channels to better leverage SAM's zero-shot inference ability for refining the pseudo-labels; 2) A reliable pseudo-label selection module that rejects low-quality pseudo-labels based on Consistency of Multiple SAM Outputs (CMSO) under input perturbations with T3IE; and 3) A reliability-aware training procedure in the unlabeled target domain where reliable pseudo-labels are used for supervision and unreliable parts are regularized by entropy minimization. Experiments conducted on two multi-domain medical image segmentation datasets for fetal brain and the prostate respectively demonstrate that: 1) SRPL-SFDA effectively enhances pseudo-label quality in the unlabeled target domain, and improves SFDA performance by leveraging the reliability-aware training; 2) SRPL-SFDA outperformed state-of-the-art SFDA methods, and its performance is close to that of supervised training in the target domain. The code of this work is available online: https://github.com/HiLab-git/SRPL-SFDA.

Evidential Deep Learning with Spectral-Spatial Uncertainty Disentanglement for Open-Set Hyperspectral Domain Generalization

Open-set domain generalization(OSDG) for hyperspectral image classification presents significant challenges due to the presence of unknown classes in target domains and the need for models to generalize across multiple unseen domains without target-specific adaptation. Existing domain adaptation methods assume access to target domain data during training and fail to address the fundamental issue of domain shift when unknown classes are present, leading to negative transfer and reduced classification performance. To address these limitations, we propose a novel open-set domain generalization framework that combines four key components: Spectrum-Invariant Frequency Disentanglement (SIFD) for domain-agnostic feature extraction, Dual-Channel Residual Network (DCRN) for robust spectral-spatial feature learning, Evidential Deep Learning (EDL) for uncertainty quantification, and Spectral-Spatial Uncertainty Disentanglement (SSUD) for reliable open-set classification. The SIFD module extracts domain-invariant spectral features in the frequency domain through attention-weighted frequency analysis and domain-agnostic regularization, while DCRN captures complementary spectral and spatial information via parallel pathways with adaptive fusion. EDL provides principled uncertainty estimation using Dirichlet distributions, enabling the SSUD module to make reliable open-set decisions through uncertainty-aware pathway weighting and adaptive rejection thresholding. Experimental results on three cross-scene hyperspectral classification tasks show that our approach achieves performance comparable to state-of-the-art domain adaptation methods while requiring no access to the target domain during training. The implementation will be made available at https://github.com/amir-khb/SSUDOSDG upon acceptance.

AIR: Zero-shot Generative Model Adaptation with Iterative Refinement

Zero-shot generative model adaptation (ZSGM) aims to adapt a pre-trained generator to a target domain using only text guidance and without any samples from the target domain. Central to recent ZSGM approaches are directional loss which use the text guidance in the form of aligning the image offset with text offset in the embedding space of a vision-language model like CLIP. This is similar to the analogical reasoning in NLP where the offset between one pair of words is used to identify a missing element in another pair by aligning the offset between these two pairs. However, a major limitation of existing ZSGM methods is that the learning objective assumes the complete alignment between image offset and text offset in the CLIP embedding space, resulting in quality degrade in generated images. Our work makes two main contributions. Inspired by the offset misalignment studies in NLP, as our first contribution, we perform an empirical study to analyze the misalignment between text offset and image offset in CLIP embedding space for various large publicly available datasets. Our important finding is that offset misalignment in CLIP embedding space is correlated with concept distance, i.e., close concepts have a less offset misalignment. To address the limitations of the current approaches, as our second contribution, we propose Adaptation with Iterative Refinement (AIR) which is the first ZSGM approach to focus on improving target domain image quality based on our new insight on offset misalignment.Qualitative, quantitative, and user study in 26 experiment setups consistently demonstrate the proposed AIR approach achieves SOTA performance. Additional experiments are in Supp.

RoCA: Robust Cross-Domain End-to-End Autonomous Driving

End-to-end (E2E) autonomous driving has recently emerged as a new paradigm, offering significant potential. However, few studies have looked into the practical challenge of deployment across domains (e.g., cities). Although several works have incorporated Large Language Models (LLMs) to leverage their open-world knowledge, LLMs do not guarantee cross-domain driving performance and may incur prohibitive retraining costs during domain adaptation. In this paper, we propose RoCA, a novel framework for robust cross-domain E2E autonomous driving. RoCA formulates the joint probabilistic distribution over the tokens that encode ego and surrounding vehicle information in the E2E pipeline. Instantiating with a Gaussian process (GP), RoCA learns a set of basis tokens with corresponding trajectories, which span diverse driving scenarios. Then, given any driving scene, it is able to probabilistically infer the future trajectory. By using RoCA together with a base E2E model in source-domain training, we improve the generalizability of the base model, without requiring extra inference computation. In addition, RoCA enables robust adaptation on new target domains, significantly outperforming direct finetuning. We extensively evaluate RoCA on various cross-domain scenarios and show that it achieves strong domain generalization and adaptation performance.

AutoMind: Adaptive Knowledgeable Agent for Automated Data Science

Large Language Model (LLM) agents have shown great potential in addressing real-world data science problems. LLM-driven data science agents promise to automate the entire machine learning pipeline, yet their real-world effectiveness remains limited. Existing frameworks depend on rigid, pre-defined workflows and inflexible coding strategies; consequently, they excel only on relatively simple, classical problems and fail to capture the empirical expertise that human practitioners bring to complex, innovative tasks. In this work, we introduce AutoMind, an adaptive, knowledgeable LLM-agent framework that overcomes these deficiencies through three key advances: (1) a curated expert knowledge base that grounds the agent in domain expert knowledge, (2) an agentic knowledgeable tree search algorithm that strategically explores possible solutions, and (3) a self-adaptive coding strategy that dynamically tailors code generation to task complexity. Evaluations on two automated data science benchmarks demonstrate that AutoMind delivers superior performance versus state-of-the-art baselines. Additional analyses confirm favorable effectiveness, efficiency, and qualitative solution quality, highlighting AutoMind as an efficient and robust step toward fully automated data science.

Adapting Vision-Language Foundation Model for Next Generation Medical Ultrasound Image Analysis

Medical ultrasonography is an essential imaging technique for examining superficial organs and tissues, including lymph nodes, breast, and thyroid. It employs high-frequency ultrasound waves to generate detailed images of the internal structures of the human body. However, manually contouring regions of interest in these images is a labor-intensive task that demands expertise and often results in inconsistent interpretations among individuals. Vision-language foundation models, which have excelled in various computer vision applications, present new opportunities for enhancing ultrasound image analysis. Yet, their performance is hindered by the significant differences between natural and medical imaging domains. This research seeks to overcome these challenges by developing domain adaptation methods for vision-language foundation models. In this study, we explore the fine-tuning pipeline for vision-language foundation models by utilizing large language model as text refiner with special-designed adaptation strategies and task-driven heads. Our approach has been extensively evaluated on six ultrasound datasets and two tasks: segmentation and classification. The experimental results show that our method can effectively improve the performance of vision-language foundation models for ultrasound image analysis, and outperform the existing state-of-the-art vision-language and pure foundation models. The source code of this study is available at https://github.com/jinggqu/NextGen-UIA.