End-to-end Clinical Event Extraction from Chinese Electronic Health Record

Event extraction is an important work of medical text processing. According to the complex characteristics of medical text annotation, we use the end-to-end event extraction model to enhance the output formatting information of events. Through pre training and fine-tuning, we can extract the attributes of the four dimensions of medical text: anatomical position, subject word, description word and occurrence state. On the test set, the accuracy rate was 0.4511, the recall rate was 0.3928, and the F1 value was 0.42. The method of this model is simple, and it has won the second place in the task of mining clinical discovery events (task2) in the Chinese electronic medical record of the seventh China health information processing Conference (chip2021).

Ret3D: Rethinking Object Relations for Efficient 3D Object Detection in Driving Scenes

Current efficient LiDAR-based detection frameworks are lacking in exploiting object relations, which naturally present in both spatial and temporal manners. To this end, we introduce a simple, efficient, and effective two-stage detector, termed as Ret3D. At the core of Ret3D is the utilization of novel intra-frame and inter-frame relation modules to capture the spatial and temporal relations accordingly. More Specifically, intra-frame relation module (IntraRM) encapsulates the intra-frame objects into a sparse graph and thus allows us to refine the object features through efficient message passing. On the other hand, inter-frame relation module (InterRM) densely connects each object in its corresponding tracked sequences dynamically, and leverages such temporal information to further enhance its representations efficiently through a lightweight transformer network. We instantiate our novel designs of IntraRM and InterRM with general center-based or anchor-based detectors and evaluate them on Waymo Open Dataset (WOD). With negligible extra overhead, Ret3D achieves the state-of-the-art performance, being 5.5% and 3.2% higher than the recent competitor in terms of the LEVEL 1 and LEVEL 2 mAPH metrics on vehicle detection, respectively.

Mining Relations among Cross-Frame Affinities for Video Semantic Segmentation

The essence of video semantic segmentation (VSS) is how to leverage temporal information for prediction. Previous efforts are mainly devoted to developing new techniques to calculate the cross-frame affinities such as optical flow and attention. Instead, this paper contributes from a different angle by mining relations among cross-frame affinities, upon which better temporal information aggregation could be achieved. We explore relations among affinities in two aspects: single-scale intrinsic correlations and multi-scale relations. Inspired by traditional feature processing, we propose Single-scale Affinity Refinement (SAR) and Multi-scale Affinity Aggregation (MAA). To make it feasible to execute MAA, we propose a Selective Token Masking (STM) strategy to select a subset of consistent reference tokens for different scales when calculating affinities, which also improves the efficiency of our method. At last, the cross-frame affinities strengthened by SAR and MAA are adopted for adaptively aggregating temporal information. Our experiments demonstrate that the proposed method performs favorably against state-of-the-art VSS methods. The code is publicly available at https://github.com/GuoleiSun/VSS-MRCFA

Discovering novel systemic biomarkers in photos of the external eye

External eye photos were recently shown to reveal signs of diabetic retinal disease and elevated HbA1c. In this paper, we evaluate if external eye photos contain information about additional systemic medical conditions. We developed a deep learning system (DLS) that takes external eye photos as input and predicts multiple systemic parameters, such as those related to the liver (albumin, AST); kidney (eGFR estimated using the race-free 2021 CKD-EPI creatinine equation, the urine ACR); bone & mineral (calcium); thyroid (TSH); and blood count (Hgb, WBC, platelets). Development leveraged 151,237 images from 49,015 patients with diabetes undergoing diabetic eye screening in 11 sites across Los Angeles county, CA. Evaluation focused on 9 pre-specified systemic parameters and leveraged 3 validation sets (A, B, C) spanning 28,869 patients with and without diabetes undergoing eye screening in 3 independent sites in Los Angeles County, CA, and the greater Atlanta area, GA. We compared against baseline models incorporating available clinicodemographic variables (e.g. age, sex, race/ethnicity, years with diabetes). Relative to the baseline, the DLS achieved statistically significant superior performance at detecting AST>36, calcium<8.6, eGFR<60, Hgb<11, platelets<150, ACR>=300, and WBC<4 on validation set A (a patient population similar to the development sets), where the AUC of DLS exceeded that of the baseline by 5.2-19.4%. On validation sets B and C, with substantial patient population differences compared to the development sets, the DLS outperformed the baseline for ACR>=300 and Hgb<11 by 7.3-13.2%. Our findings provide further evidence that external eye photos contain important biomarkers of systemic health spanning multiple organ systems. Further work is needed to investigate whether and how these biomarkers can be translated into clinical impact.

MSP-Former: Multi-Scale Projection Transformer for Single Image Desnowing

Image restoration of snow scenes in severe weather is a difficult task. Snow images have complex degradations and are cluttered over clean images, changing the distribution of clean images. The previous methods based on CNNs are challenging to remove perfectly in restoring snow scenes due to their local inductive biases' lack of a specific global modeling ability. In this paper, we apply the vision transformer to the task of snow removal from a single image. Specifically, we propose a parallel network architecture split along the channel, performing local feature refinement and global information modeling separately. We utilize a channel shuffle operation to combine their respective strengths to enhance network performance. Second, we propose the MSP module, which utilizes multi-scale avgpool to aggregate information of different sizes and simultaneously performs multi-scale projection self-attention on multi-head self-attention to improve the representation ability of the model under different scale degradations. Finally, we design a lightweight and simple local capture module, which can refine the local capture capability of the model. In the experimental part, we conduct extensive experiments to demonstrate the superiority of our method. We compared the previous snow removal methods on three snow scene datasets. The experimental results show that our method surpasses the state-of-the-art methods with fewer parameters and computation. We achieve substantial growth by 1.99dB and SSIM 0.03 on the CSD test dataset. On the SRRS and Snow100K datasets, we also increased PSNR by 2.47dB and 1.62dB compared with the Transweather approach and improved by 0.03 in SSIM. In the visual comparison section, our MSP-Former also achieves better visual effects than existing methods, proving the usability of our method.

Towards Real-time High-Definition Image Snow Removal: Efficient Pyramid Network with Asymmetrical Encoder-decoder Architecture

In winter scenes, the degradation of images taken under snow can be pretty complex, where the spatial distribution of snowy degradation is varied from image to image. Recent methods adopt deep neural networks to directly recover clean scenes from snowy images. However, due to the paradox caused by the variation of complex snowy degradation, achieving reliable High-Definition image desnowing performance in real time is a considerable challenge. We develop a novel Efficient Pyramid Network with asymmetrical encoder-decoder architecture for real-time HD image desnowing. The general idea of our proposed network is to utilize the multi-scale feature flow fully and implicitly mine clean cues from features. Compared with previous state-of-the-art desnowing methods, our approach achieves a better complexity-performance trade-off and effectively handles the processing difficulties of HD and Ultra-HD images. The extensive experiments on three large-scale image desnowing datasets demonstrate that our method surpasses all state-of-the-art approaches by a large margin both quantitatively and qualitatively, boosting the PSNR metric from 31.76 dB to 34.10 dB on the CSD test dataset and from 28.29 dB to 30.87 dB on the SRRS test dataset.

Robust and Efficient Medical Imaging with Self-Supervision

Recent progress in Medical Artificial Intelligence (AI) has delivered systems that can reach clinical expert level performance. However, such systems tend to demonstrate sub-optimal "out-of-distribution" performance when evaluated in clinical settings different from the training environment. A common mitigation strategy is to develop separate systems for each clinical setting using site-specific data [1]. However, this quickly becomes impractical as medical data is time-consuming to acquire and expensive to annotate [2]. Thus, the problem of "data-efficient generalization" presents an ongoing difficulty for Medical AI development. Although progress in representation learning shows promise, their benefits have not been rigorously studied, specifically for out-of-distribution settings. To meet these challenges, we present REMEDIS, a unified representation learning strategy to improve robustness and data-efficiency of medical imaging AI. REMEDIS uses a generic combination of large-scale supervised transfer learning with self-supervised learning and requires little task-specific customization. We study a diverse range of medical imaging tasks and simulate three realistic application scenarios using retrospective data. REMEDIS exhibits significantly improved in-distribution performance with up to 11.5% relative improvement in diagnostic accuracy over a strong supervised baseline. More importantly, our strategy leads to strong data-efficient generalization of medical imaging AI, matching strong supervised baselines using between 1% to 33% of retraining data across tasks. These results suggest that REMEDIS can significantly accelerate the life-cycle of medical imaging AI development thereby presenting an important step forward for medical imaging AI to deliver broad impact.

Towards Efficient Single Image Dehazing and Desnowing

Removing adverse weather conditions like rain, fog, and snow from images is a challenging problem. Although the current recovery algorithms targeting a specific condition have made impressive progress, it is not flexible enough to deal with various degradation types. We propose an efficient and compact image restoration network named DAN-Net (Degradation-Adaptive Neural Network) to address this problem, which consists of multiple compact expert networks with one adaptive gated neural. A single expert network efficiently addresses specific degradation in nasty winter scenes relying on the compact architecture and three novel components. Based on the Mixture of Experts strategy, DAN-Net captures degradation information from each input image to adaptively modulate the outputs of task-specific expert networks to remove various adverse winter weather conditions. Specifically, it adopts a lightweight Adaptive Gated Neural Network to estimate gated attention maps of the input image, while different task-specific experts with the same topology are jointly dispatched to process the degraded image. Such novel image restoration pipeline handles different types of severe weather scenes effectively and efficiently. It also enjoys the benefit of coordinate boosting in which the whole network outperforms each expert trained without coordination. Extensive experiments demonstrate that the presented manner outperforms the state-of-the-art single-task methods on image quality and has better inference efficiency. Furthermore, we have collected the first real-world winter scenes dataset to evaluate winter image restoration methods, which contains various hazy and snowy images snapped in winter. Both the dataset and source code will be publicly available.

HOI4D: A 4D Egocentric Dataset for Category-Level Human-Object Interaction

We present HOI4D, a large-scale 4D egocentric dataset with rich annotations, to catalyze the research of category-level human-object interaction. HOI4D consists of 2.4M RGB-D egocentric video frames over 4000 sequences collected by 4 participants interacting with 800 different object instances from 16 categories over 610 different indoor rooms. Frame-wise annotations for panoptic segmentation, motion segmentation, 3D hand pose, category-level object pose and hand action have also been provided, together with reconstructed object meshes and scene point clouds. With HOI4D, we establish three benchmarking tasks to promote category-level HOI from 4D visual signals including semantic segmentation of 4D dynamic point cloud sequences, category-level object pose tracking, and egocentric action segmentation with diverse interaction targets. In-depth analysis shows HOI4D poses great challenges to existing methods and produces great research opportunities.

Towards Reliable and Explainable AI Model for Solid Pulmonary Nodule Diagnosis

Lung cancer has the highest mortality rate of deadly cancers in the world. Early detection is essential to treatment of lung cancer. However, detection and accurate diagnosis of pulmonary nodules depend heavily on the experiences of radiologists and can be a heavy workload for them. Computer-aided diagnosis (CAD) systems have been developed to assist radiologists in nodule detection and diagnosis, greatly easing the workload while increasing diagnosis accuracy. Recent development of deep learning, greatly improved the performance of CAD systems. However, lack of model reliability and interpretability remains a major obstacle for its large-scale clinical application. In this work, we proposed a multi-task explainable deep-learning model for pulmonary nodule diagnosis. Our neural model can not only predict lesion malignancy but also identify relevant manifestations. Further, the location of each manifestation can also be visualized for visual interpretability. Our proposed neural model achieved a test AUC of 0.992 on LIDC public dataset and a test AUC of 0.923 on our in-house dataset. Moreover, our experimental results proved that by incorporating manifestation identification tasks into the multi-task model, the accuracy of the malignancy classification can also be improved. This multi-task explainable model may provide a scheme for better interaction with the radiologists in a clinical environment.