Think and Retrieval: A Hypothesis Knowledge Graph Enhanced Medical Large Language Models

We explore how the rise of Large Language Models (LLMs) significantly impacts task performance in the field of Natural Language Processing. We focus on two strategies, Retrieval-Augmented Generation (RAG) and Fine-Tuning (FT), and propose the Hypothesis Knowledge Graph Enhanced (HyKGE) framework, leveraging a knowledge graph to enhance medical LLMs. By integrating LLMs and knowledge graphs, HyKGE demonstrates superior performance in addressing accuracy and interpretability challenges, presenting potential applications in the medical domain. Our evaluations using real-world datasets highlight HyKGE's superiority in providing accurate knowledge with precise confidence, particularly in complex and difficult scenarios. The code will be available until published.

Spatially and Robustly Hybrid Mixture Regression Model for Inference of Spatial Dependence

In this paper, we propose a Spatial Robust Mixture Regression model to investigate the relationship between a response variable and a set of explanatory variables over the spatial domain, assuming that the relationships may exhibit complex spatially dynamic patterns that cannot be captured by constant regression coefficients. Our method integrates the robust finite mixture Gaussian regression model with spatial constraints, to simultaneously handle the spatial nonstationarity, local homogeneity, and outlier contaminations. Compared with existing spatial regression models, our proposed model assumes the existence a few distinct regression models that are estimated based on observations that exhibit similar response-predictor relationships. As such, the proposed model not only accounts for nonstationarity in the spatial trend, but also clusters observations into a few distinct and homogenous groups. This provides an advantage on interpretation with a few stationary sub-processes identified that capture the predominant relationships between response and predictor variables. Moreover, the proposed method incorporates robust procedures to handle contaminations from both regression outliers and spatial outliers. By doing so, we robustly segment the spatial domain into distinct local regions with similar regression coefficients, and sporadic locations that are purely outliers. Rigorous statistical hypothesis testing procedure has been designed to test the significance of such segmentation. Experimental results on many synthetic and real-world datasets demonstrate the robustness, accuracy, and effectiveness of our proposed method, compared with other robust finite mixture regression, spatial regression and spatial segmentation methods.