Abstract:The growing adoption of electronic health record (EHR) systems has provided unprecedented opportunities for predictive modeling to guide clinical decision making. Structured EHRs contain longitudinal observations of patients across hospital visits, where each visit is represented by a set of medical codes. While sequence-based, graph-based, and graph-enhanced sequence approaches have been developed to capture rich code interactions over time or within the same visits, they often overlook the inherent heterogeneous roles of medical codes arising from distinct clinical characteristics and contexts. To this end, in this study we propose the Disease Trajectory-aware Transformer for EHR (DT-BEHRT), a graph-enhanced sequential architecture that disentangles disease trajectories by explicitly modeling diagnosis-centric interactions within organ systems and capturing asynchronous progression patterns. To further enhance the representation robustness, we design a tailored pre-training methodology that combines trajectory-level code masking with ontology-informed ancestor prediction, promoting semantic alignment across multiple modeling modules. Extensive experiments on multiple benchmark datasets demonstrate that DT-BEHRT achieves strong predictive performance and provides interpretable patient representations that align with clinicians' disease-centered reasoning. The source code is publicly accessible at https://github.com/GatorAIM/DT-BEHRT.git.
Abstract:Prior work has explored multi-turn interaction and feedback for LLM writing, but evaluations still largely center on prompts and localized feedback, leaving persistent public reception in online communities underexamined. We test whether broadcast community discussion improves stand-up comedy writing in a controlled multi-agent sandbox: in the discussion condition, critic and audience threads are recorded, filtered, stored as social memory, and later retrieved to condition subsequent generations, whereas the baseline omits discussion. Across 50 rounds (250 paired monologues) judged by five expert annotators using A/B preference and a 15-item rubric, discussion wins 75.6% of instances and improves Craft/Clarity (Δ = 0.440) and Social Response (Δ = 0.422), with occasional increases in aggressive humor.
Abstract:As robots become increasingly integrated into daily life, understanding responses to robot mistreatment carries important ethical and design implications. This mixed-methods study (N = 201) examined how anthropomorphic levels and moral foundations shape reactions to robot abuse. Participants viewed videos depicting physical mistreatment of robots varying in humanness (Spider, Twofoot, Humanoid) and completed measures assessing moral foundations, anger, and social distance. Results revealed that anthropomorphism determines whether people extend moral consideration to robots, while moral foundations shape how they reason about such consideration. Qualitative analysis revealed distinct reasoning patterns: low-progressivism individuals employed character-based judgments, while high-progressivism individuals engaged in future-oriented moral deliberation. Findings offer implications for robot design and policy communication.
Abstract:Social robots like Moxie are designed to form strong emotional bonds with children, but their abrupt discontinuation can cause significant struggles and distress to children. When these services end, the resulting harm raises complex questions of who bears responsibility when children's emotional bonds are broken. Using the Moxie shutdown as a case study through a qualitative survey of 72 U.S. participants, our findings show that the responsibility is viewed as a shared duty across the robot company, parents, developers, and government. However, these attributions varied by political ideology and parental status of whether they have children. Participants' perceptions of whether the robot service should continue are highly polarized; supporters propose technical, financial, and governmental pathways for continuity, while opponents cite business realities and risks of unhealthy emotional dependency. Ultimately, this research contributes an empirically grounded shared responsibility framework for safeguarding child-robot companionship by detailing how accountability is distributed and contested, informing concrete design and policy implications to mitigate the emotional harm of robot discontinuation.
Abstract:Robots with anthropomorphic features are increasingly shaping how humans perceive and morally engage with them. Our research investigates how different levels of anthropomorphism influence protective responses to robot abuse, extending the Computers as Social Actors (CASA) and uncanny valley theories into a moral domain. In an experiment, we invite 201 participants to view videos depicting abuse toward a robot with low (Spider), moderate (Two-Foot), or high (Humanoid) anthropomorphism. To provide a comprehensive analysis, we triangulate three modalities: self-report surveys measuring emotions and uncanniness, physiological data from automated facial expression analysis, and qualitative reflections. Findings indicate that protective responses are not linear. The moderately anthropomorphic Two-Foot robot, rated highest in eeriness and "spine-tingling" sensations consistent with the uncanny valley, elicited the strongest physiological anger expressions. Self-reported anger and guilt are significantly higher for both the Two-Foot and Humanoid robots compared to the Spider. Qualitative findings further reveal that as anthropomorphism increases, moral reasoning shifts from technical assessments of property damage to condemnation of the abuser's character, while governance proposals expand from property law to calls for quasi-animal rights and broader societal responsibility. These results suggest that the uncanny valley does not dampen moral concern but paradoxically heightens protective impulses, offering critical implications for robot design, policy, and future legal frameworks.
Abstract:With the rapid advancement of large language models (LLMs), Multi-agent Systems (MAS) have achieved significant progress in various application scenarios. However, substantial challenges remain in designing versatile, robust, and efficient platforms for agent deployment. To address these limitations, we propose \textbf{LightAgent}, a lightweight yet powerful agentic framework, effectively resolving the trade-off between flexibility and simplicity found in existing frameworks. LightAgent integrates core functionalities such as Memory (mem0), Tools, and Tree of Thought (ToT), while maintaining an extremely lightweight structure. As a fully open-source solution, it seamlessly integrates with mainstream chat platforms, enabling developers to easily build self-learning agents. We have released LightAgent at \href{https://github.com/wxai-space/LightAgent}{https://github.com/wxai-space/LightAgent}
Abstract:The rise of Large Language Models (LLMs) has enabled the development of specialized AI agents with domain-specific reasoning and interaction capabilities, particularly in healthcare. While recent frameworks simulate medical decision-making, they largely focus on single-turn tasks where a doctor agent receives full case information upfront -- diverging from the real-world diagnostic process, which is inherently uncertain, interactive, and iterative. In this paper, we introduce MIMIC-Patient, a structured dataset built from the MIMIC-III electronic health records (EHRs), designed to support dynamic, patient-level simulations. Building on this, we propose DynamiCare, a novel dynamic multi-agent framework that models clinical diagnosis as a multi-round, interactive loop, where a team of specialist agents iteratively queries the patient system, integrates new information, and dynamically adapts its composition and strategy. We demonstrate the feasibility and effectiveness of DynamiCare through extensive experiments, establishing the first benchmark for dynamic clinical decision-making with LLM-powered agents.
Abstract:Large Language Models (LLMs) are increasingly equipped with capabilities of real-time web search and integrated with protocols like Model Context Protocol (MCP). This extension could introduce new security vulnerabilities. We present a systematic investigation of LLM vulnerabilities to hidden adversarial prompts through malicious font injection in external resources like webpages, where attackers manipulate code-to-glyph mapping to inject deceptive content which are invisible to users. We evaluate two critical attack scenarios: (1) "malicious content relay" and (2) "sensitive data leakage" through MCP-enabled tools. Our experiments reveal that indirect prompts with injected malicious font can bypass LLM safety mechanisms through external resources, achieving varying success rates based on data sensitivity and prompt design. Our research underscores the urgent need for enhanced security measures in LLM deployments when processing external content.
Abstract:Single-agent LLMs hit hard limits--finite context, role overload, and brittle domain transfer. Conventional multi-agent fixes soften those edges yet expose fresh pains: ill-posed decompositions, fuzzy contracts, and verification overhead that blunts the gains. We therefore present Know-The-Ropes (KtR), a framework that converts domain priors into an algorithmic blueprint hierarchy, in which tasks are recursively split into typed, controller-mediated subtasks, each solved zero-shot or with the lightest viable boost (e.g., chain-of-thought, micro-tune, self-check). Grounded in the No-Free-Lunch theorem, KtR trades the chase for a universal prompt for disciplined decomposition. On the Knapsack problem (3-8 items), three GPT-4o-mini agents raise accuracy from 3% zero-shot to 95% on size-5 instances after patching a single bottleneck agent. On the tougher Task-Assignment problem (6-15 jobs), a six-agent o3-mini blueprint hits 100% up to size 10 and 84% on sizes 13-15, versus 11% zero-shot. Algorithm-aware decomposition plus targeted augmentation thus turns modest models into reliable collaborators--no ever-larger monoliths required.
Abstract:Large Language Models (LLMs) have shown promise in clinical decision support, yet their application to triage remains underexplored. We systematically investigate the capabilities of LLMs in emergency department triage through two key dimensions: (1) robustness to distribution shifts and missing data, and (2) counterfactual analysis of intersectional biases across sex and race. We assess multiple LLM-based approaches, ranging from continued pre-training to in-context learning, as well as machine learning approaches. Our results indicate that LLMs exhibit superior robustness, and we investigate the key factors contributing to the promising LLM-based approaches. Furthermore, in this setting, we identify gaps in LLM preferences that emerge in particular intersections of sex and race. LLMs generally exhibit sex-based differences, but they are most pronounced in certain racial groups. These findings suggest that LLMs encode demographic preferences that may emerge in specific clinical contexts or particular combinations of characteristics.