Abstract:Dynamic MRI plays a vital role in clinical practice by capturing both spatial details and dynamic motion, but its high spatiotemporal resolution is often limited by long scan times. Deep learning (DL)-based methods have shown promising performance in accelerating dynamic MRI. However, most existing algorithms rely on large fully-sampled datasets for training, which are difficult to acquire. Recently, implicit neural representation (INR) has emerged as a powerful scan-specific paradigm for accelerated MRI, which models signals as a continuous function over spatiotemporal coordinates. Although this approach achieves efficient continuous modeling of dynamic images and robust reconstruction, it faces challenges in recovering fine details and increasing computational demands for high dimensional data representation. To enhance both efficiency and reconstruction quality, we propose TenF-INR, a novel patch-based unsupervised framework that employs INR to model bases of tensor decomposition, enabling efficient and accurate modeling of dynamic MR images with learnable tensor functions. By exploiting strong correlations in similar spatial image patches and in the temporal direction, TenF-INR enforces multidimensional low-rankness and implements patch-based reconstruction with the benefits of continuous modeling. We compare TenF-INR with state-of-the-art methods, including supervised DL methods and unsupervised approaches. Experimental results demonstrate that TenF-INR achieves high acceleration factors up to 21, outperforming all comparison methods in image quality, temporal fidelity, and quantitative metrics, even surpassing the supervised methods.
Abstract:The segmentation of substantial brain lesions is a significant and challenging task in the field of medical image segmentation. Substantial brain lesions in brain imaging exhibit high heterogeneity, with indistinct boundaries between lesion regions and normal brain tissue. Small lesions in single slices are difficult to identify, making the accurate and reproducible segmentation of abnormal regions, as well as their feature description, highly complex. Existing methods have the following limitations: 1) They rely solely on single-modal information for learning, neglecting the multi-modal information commonly used in diagnosis. This hampers the ability to comprehensively acquire brain lesion information from multiple perspectives and prevents the effective integration and utilization of multi-modal data inputs, thereby limiting a holistic understanding of lesions. 2) They are constrained by the amount of data available, leading to low sensitivity to small lesions and difficulty in detecting subtle pathological changes. 3) Current SAM-based models rely on external prompts, which cannot achieve automatic segmentation and, to some extent, affect diagnostic efficiency.To address these issues, we have developed a large-scale fully automated segmentation model specifically designed for brain lesion segmentation, named BrainSegDMLF. This model has the following features: 1) Dynamic Modal Interactive Fusion (DMIF) module that processes and integrates multi-modal data during the encoding process, providing the SAM encoder with more comprehensive modal information. 2) Layer-by-Layer Upsampling Decoder, enabling the model to extract rich low-level and high-level features even with limited data, thereby detecting the presence of small lesions. 3) Automatic segmentation masks, allowing the model to generate lesion masks automatically without requiring manual prompts.
Abstract:Galloping is a common high-speed gait in both animals and quadrupedal robots, yet its energetic characteristics remain insufficiently explored. This study systematically analyzes a large number of possible galloping gaits by categorizing them based on the number of flight phases per stride and the phase relationships between the front and rear legs, following Hildebrand's framework for asymmetrical gaits. Using the A1 quadrupedal robot from Unitree, we model galloping dynamics as a hybrid dynamical system and employ trajectory optimization (TO) to minimize the cost of transport (CoT) across a range of speeds. Our results reveal that rotary and transverse gallop footfall sequences exhibit no fundamental energetic difference, despite variations in body yaw and roll motion. However, the number of flight phases significantly impacts energy efficiency: galloping with no flight phases is optimal at lower speeds, whereas galloping with two flight phases minimizes energy consumption at higher speeds. We validate these findings using a quadratic programming (QP)-based controller, developed in our previous work, in Gazebo simulations. These insights advance the understanding of quadrupedal locomotion energetics and may inform future legged robot designs for adaptive, energy-efficient gait transitions.
Abstract:Dynamic MR images possess various transformation symmetries,including the rotation symmetry of local features within the image and along the temporal dimension. Utilizing these symmetries as prior knowledge can facilitate dynamic MR imaging with high spatiotemporal resolution. Equivariant CNN is an effective tool to leverage the symmetry priors. However, current equivariant CNN methods fail to fully exploit these symmetry priors in dynamic MR imaging. In this work, we propose a novel framework of Spatiotemporal Rotation-Equivariant CNN (SRE-CNN), spanning from the underlying high-precision filter design to the construction of the temporal-equivariant convolutional module and imaging model, to fully harness the rotation symmetries inherent in dynamic MR images. The temporal-equivariant convolutional module enables exploitation the rotation symmetries in both spatial and temporal dimensions, while the high-precision convolutional filter, based on parametrization strategy, enhances the utilization of rotation symmetry of local features to improve the reconstruction of detailed anatomical structures. Experiments conducted on highly undersampled dynamic cardiac cine data (up to 20X) have demonstrated the superior performance of our proposed approach, both quantitatively and qualitatively.
Abstract:Quantitative T1rho parameter mapping has shown promise in clinical and research studies. However, it suffers from long scan times. Deep learning-based techniques have been successfully applied in accelerated quantitative MR parameter mapping. However, most methods require fully-sampled training dataset, which is impractical in the clinic. In this study, a novel subject-specific unsupervised method based on the implicit neural representation is proposed to reconstruct images from highly undersampled k-space data and estimate parameter maps from reconstructions, which only takes spatiotemporal coordinates as the input. Specifically, the proposed method learned a implicit neural representation of the MR images driven by two explicit priors of images (or k-space data), including the low-rankness of Hankel matrix, and the self-consistency of k-space data. The ablation experiments show that the proposed method can characterize the physical priors of MR images well. Moreover,experimental results of retrospective and prospective data show that the proposed method outperforms the state-of-the-art methods in terms of supressing artifacts and achieving the lowest error.
Abstract:This study explores the dynamics of asymmetrical bounding gaits in quadrupedal robots, focusing on the integration of torso pitching and hip motion to enhance speed and stability. Traditional control strategies often enforce a fixed posture, minimizing natural body movements to simplify the control problem. However, this approach may overlook the inherent dynamical advantages found in natural locomotion. By considering the robot as two interconnected segments, we concentrate on stance leg motion while allowing passive torso oscillation, drawing inspiration from natural dynamics and underactuated robotics principles. Our control scheme employs Linear Inverted Pendulum (LIP) and Spring-Loaded Inverted Pendulum (SLIP) models to govern front and rear leg movements independently. This approach has been validated through extensive simulations and hardware experiments, demonstrating successful high-speed locomotion with top speeds nearing 4 m/s and reduced ground reaction forces, indicating a more efficient gait. Furthermore, unlike conventional methods, our strategy leverages natural torso oscillations to aid leg circulation and stride length, aligning robot dynamics more closely with biological counterparts. Our findings suggest that embracing the natural dynamics of quadrupedal movement, particularly in asymmetrical gaits like bounding, can lead to more stable, efficient, and high-speed robotic locomotion. This investigation lays the groundwork for future studies on versatile and dynamic quadrupedal gaits and their potential applications in scenarios demanding rapid and effective locomotion.
Abstract:In this paper, we introduce a novel class of neural differential equation, which are intrinsically Lyapunov stable, exponentially stable or passive. We take a recently proposed Polyak Lojasiewicz network (PLNet) as an Lyapunov function and then parameterize the vector field as the descent directions of the Lyapunov function. The resulting models have a same structure as the general Hamiltonian dynamics, where the Hamiltonian is lower- and upper-bounded by quadratic functions. Moreover, it is also positive definite w.r.t. either a known or learnable equilibrium. We illustrate the effectiveness of the proposed model on a damped double pendulum system.
Abstract:The Coded Aperture Snapshot Spectral Compressive Imaging (CASSI) system modulates three-dimensional hyperspectral images into two-dimensional compressed images in a single exposure. Subsequently, three-dimensional hyperspectral images (HSI) can be reconstructed from the two-dimensional compressed measurements using reconstruction algorithms. Among these methods, deep unfolding techniques have demonstrated excellent performance, with RDLUF-MixS^2 achieving the best reconstruction results. However, RDLUF-MixS^2 requires extensive training time, taking approximately 14 days to train RDLUF-MixS^2-9stg on a single RTX 3090 GPU, making it computationally expensive. Furthermore, RDLUF-MixS^2 performs poorly on real data, resulting in significant artifacts in the reconstructed images. In this study, we introduce the Dense-spatial Spectral-attention Transformer (DST) into the Proximal Gradient Descent Unfolding Framework (PGDUF), creating a novel approach called Proximal Gradient Descent Unfolding Dense-spatial Spectral-attention Transformer (PGDUDST). Compared to RDLUF-MixS^2, PGDUDST not only surpasses the network reconstruction performance limit of RDLUF-MixS^2 but also achieves faster convergence. PGDUDST requires only 58% of the training time of RDLUF-MixS^2-9stg to achieve comparable reconstruction results. Additionally, PGDUDST significantly alleviates the artifact issues caused by RDLUF-MixS^2 in real experimental data, demonstrating superior performance and producing clearer reconstructed images.
Abstract:In the field of parallel imaging (PI), alongside image-domain regularization methods, substantial research has been dedicated to exploring $k$-space interpolation. However, the interpretability of these methods remains an unresolved issue. Furthermore, these approaches currently face acceleration limitations that are comparable to those experienced by image-domain methods. In order to enhance interpretability and overcome the acceleration limitations, this paper introduces an interpretable framework that unifies both $k$-space interpolation techniques and image-domain methods, grounded in the physical principles of heat diffusion equations. Building upon this foundational framework, a novel $k$-space interpolation method is proposed. Specifically, we model the process of high-frequency information attenuation in $k$-space as a heat diffusion equation, while the effort to reconstruct high-frequency information from low-frequency regions can be conceptualized as a reverse heat equation. However, solving the reverse heat equation poses a challenging inverse problem. To tackle this challenge, we modify the heat equation to align with the principles of magnetic resonance PI physics and employ the score-based generative method to precisely execute the modified reverse heat diffusion. Finally, experimental validation conducted on publicly available datasets demonstrates the superiority of the proposed approach over traditional $k$-space interpolation methods, deep learning-based $k$-space interpolation methods, and conventional diffusion models in terms of reconstruction accuracy, particularly in high-frequency regions.
Abstract:Neural networks are typically sensitive to small input perturbations, leading to unexpected or brittle behaviour. We present RobustNeuralNetworks.jl: a Julia package for neural network models that are constructed to naturally satisfy a set of user-defined robustness constraints. The package is based on the recently proposed Recurrent Equilibrium Network (REN) and Lipschitz-Bounded Deep Network (LBDN) model classes, and is designed to interface directly with Julia's most widely-used machine learning package, Flux.jl. We discuss the theory behind our model parameterization, give an overview of the package, and provide a tutorial demonstrating its use in image classification, reinforcement learning, and nonlinear state-observer design.