Feynman Kac Reweighted Schrödinger Bridge Matching for Surface-Based Tau PET Harmonization

Tau PET imaging is central to tracking Alzheimer's disease progression, but systematic differences between scanners, protocols, and radiotracers across sites introduce nonbiological variability that inflates biomarker variance, reduces sensitivity to disease effects, and can bias downstream clinical assessments. Harmonization methods aim to remove these site-induced shifts while preserving biologically meaningful signal, yet existing approaches struggle when source and target cohorts differ in subgroup composition, risking conflation of site effects with biological variation such as tau-positivity status. We propose the Feynman Kac Reweighted Schröodinger Bridge Matching (FKRSBM) model to address this problem. Rather than routing data through a Gaussian noise prior as in diffusion-based methods, FKRSBM learns a direct stochastic transport process between source and target distributions via entropy-regularized optimal transport. To enforce biologically consistent transport, FKRSBM incorporates a subgroup-aware endpoint proposal derived from a Feynman Kac reweighting of the reference bridge measure, implemented entirely through stratified importance sampling at the data level and requiring no changes to the underlying bridge-matching solver or network architecture. For surface-based neuroimaging, FKRSBM employs a spherical convolutional backbone operating on cortical meshes to perform vertex-level harmonization. We evaluate the method on tau PET SUVR maps, harmonizing PI-2620 data from the HABS-HD cohort into the AV-1451 domain of ADNI. Compared against ComBat, CycleGAN, a diffusion-based method (DF), and unregularized Diffusion Schröodinger Bridge Matching (DSBM), FKRSBM achieves superior distributional alignment, reduced tau-positivity sign mismatch, stronger APOE subgroup alignment, and improved downstream disease classification performance.

A Surface-based Multimodal Framework for Multitask Analysis in Alzheimer's Disease

Alzheimer's Disease (AD) is a progressive neurodegenerative disorder, and longitudinal analysis is critical for early detection and effective intervention. Developing models capable of multimodal and multitask analysis enables a more comprehensive understanding of AD progression. However, multimodal learning remains challenged by cross-modal misalignment, non-Euclidean surface representations of cortical data, and limited data availability in small-sample clinical settings. In this work, we propose an augmented spherical data-driven multimodal framework for multitask AD analysis. A spherical diffusion model is first trained to generate paired cortical thickness and Tau PET Standardized Uptake Value Ratio (SUVR) data, enabling structurally consistent multimodal augmentation on cortical surfaces while preserving anatomical correspondence. The augmented data are subsequently used to train a contrastive learning model that learns aligned and fused cross-modal representations. This design strengthens multimodal integration and encourages more balanced representation learning. The learned imaging features are further integrated with tabular cognitive assessments and demographic variables, and processed using an in-context learning model to perform both classification and regression tasks without task-specific fine-tuning. Experiments on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset ($n = 802$) demonstrate consistent performance improvements across five diagnostic and longitudinal tasks, outperforming six baseline models.

ReactVLA: Fast and Lightweight Reactive Robot Manipulation via Improved Mean Flow Action Generation

Diffusion-based Vision-Language-Action (VLA) policies have demonstrated strong capability in modeling expressive and multimodal action distributions. However, their reliance on iterative sampling introduces substantial inference latency, which limits their applicability to reactive closed-loop robot manipulation. To address this limitation, we propose \texttt{ReactVLA}, a lightweight and low-latency VLA framework for real-time robotic manipulation. \texttt{ReactVLA} combines two complementary designs: (1) an improved Mean Flow (iMF) action generator that reduces expensive multi-step diffusion sampling to one-to-few-step action generation, and (2) Attention Residuals (AttnRes), a dynamic depth-wise feature routing mechanism that replaces uniform residual accumulation to better preserve task-relevant multimodal representations. We evaluate \texttt{ReactVLA} on large-scale simulation benchmarks, including LIBERO and RoboIMI, as well as real-world robotic manipulation tasks. Experimental results show that \texttt{ReactVLA} consistently outperforms similarly sized VLA baselines, including SmolVLA and $π_0$. On challenging precision manipulation tasks, \texttt{ReactVLA} achieves up to a 1.65$\times$ improvement in task performance while providing more than a 4$\times$ increase in inference speed compared with leading VLA models. Finally, it reduces real-world policy latency to below 38.6 ms, enabling fast reactive control on physical robot platforms. Please check out our project website at: https://game-loader.github.io/ReactVLA/.

Breaking Entropy Bounds: Accelerating RL Training via MTP with Rejection Sampling

Reinforcement learning (RL) has become a key component in modern large language models, yet the rollout stage remains the key bottleneck in RL training pipelines. Although Multi-Token Prediction (MTP) offers a natural solution to accelerate rollouts through speculative decoding, many studies have observed that MTP acceptance rates degrade significantly during RL training, leading to limited speedup performance. To address this bottleneck, we present Bebop, a systematic study of MTP in LLM post-training, and offer practical recipes to integrate MTP into large-scale RL pipelines. First, we reveal that the MTP acceptance rate is fundamentally bounded by the fluctuation of model entropy, which demonstrates a clear negative linear relationship with the rise of entropy in the RL stage. Second, we show that probabilistic rejection sampling largely alleviates the disturbance introduced by entropy in RL compared to greedy draft sampling. We further identify that the conventional MTP training objectives (cross-entropy or KL) are suboptimal in such settings, and therefore we propose a novel end-to-end TV loss that directly optimizes multi-step rejection sampling acceptance rate, yielding ~10% acceptance rate improvements, achieving up to 95% acceptance rates and up to 25% extra inference throughput gains across mathematical reasoning, code generation, and agentic tasks. Third, we test various online MTP training strategies during RL and show that pre-RL MTP training with e2e TV loss and rejection sampling achieves a consistent acceptance rate and speedup throughout the entire RL, eliminating the need for costly online MTP updating. We provide extensive experiments and analysis that validate our findings. Experimental results show our method achieves up to 1.8x end-to-end acceleration in async RL training of Qwen3.5, Qwen3.6, and Qwen3.7 models.

Precise: SDE-Consistent Stochastic Sampling for RL Post-Training of Flow-Matching Models

Reinforcement learning (RL) has become an effective way to improve prompt alignment and perceptual quality in diffusion and flow-matching generators. A critical step for applying online RL to flow matching is turning the deterministic sampling trajectory into a stochastic policy, typically by replacing the reverse-time Ordinary Differential Equation (ODE) with a Stochastic Differential Equation (SDE). The stochastic sampler, controlling the exploration behavior and denoising dynamics, is thus part of the policy, and its design can significantly affect the reward optimization performance. We break down the sampler design into two interdependent components: choosing the right amount of stochastic exploration, and discretizing the resulting SDE faithfully at the small step counts used in RL. To address the first component, we analyze the inherent tension between exploration and stability in denoising and derive an SDE schedule that balances the two. Turning to the discretization challenge, we use a toy example to show that existing samplers can deviate from the flow-matching process, either by introducing excessive discretization noise or by relying on heuristic rules that do not guarantee convergence to the data distribution. To address these issues, we propose Precise, a new stochastic sampler that balances effective exploration with stability. Crucially, Precise keeps the denoising trajectory SDE-consistent through a novel approximation that freezes the clean-latent posterior mean, resolving the excess noise issue in standard samplers. Extensive experiments demonstrate that this formulation leads to significantly faster and more stable reward optimization via reinforcement learning, achieving state-of-the-art alignment scores (e.g., PickScore, HPSv2.1) while requiring 13.1-53.2% less wall-clock training time to match the best in-domain performance of prior samplers.

Qwen-Image-2.0 Technical Report

We present Qwen-Image-2.0, an omni-capable image generation foundation model that unifies high-fidelity generation and precise image editing within a single framework. Despite recent progress, existing models still struggle with ultra-long text rendering, multilingual typography, high-resolution photorealism, robust instruction following, and efficient deployment, especially in text-rich and compositionally complex scenarios. Qwen-Image-2.0 addresses these challenges by coupling Qwen3-VL as the condition encoder with a Multimodal Diffusion Transformer for joint condition-target modeling, supported by large-scale data curation and a customized multi-stage training pipeline. This enables strong multimodal understanding while preserving flexible generation and editing capabilities. The model supports instructions of up to 1K tokens for generating text-rich content such as slides, posters, infographics, and comics, while significantly improving multilingual text fidelity and typography. It also enhances photorealistic generation with richer details, more realistic textures, and coherent lighting, and follows complex prompts more reliably across diverse styles. Extensive human evaluations show that Qwen-Image-2.0 substantially outperforms previous Qwen-Image models in both generation and editing, marking a step toward more general, reliable, and practical image generation foundation models.

NeuroAgent: LLM Agents for Multimodal Neuroimaging Analysis and Research

Multimodal neuroimaging analysis often involves complex, modality-specific preprocessing workflows that require careful configuration, quality control, and coordination across heterogeneous toolchains. Beyond preprocessing, downstream statistical analysis and disease classification commonly require task-specific code, evaluation protocols, and data-format conventions, creating additional barriers between raw acquisitions and reproducible scientific analysis. We present NeuroAgent, an LLM-driven agentic framework that automates key preprocessing and analysis steps for heterogeneous neuroimaging data, including sMRI, fMRI, dMRI, and PET, and supports interactive downstream analysis through natural-language queries. NeuroAgent employs a hierarchical multi-agent architecture with a feedback-driven Generate-Execute-Validate engine: agents autonomously generate executable preprocessing code, detect and recover from runtime errors, and validate output integrity. We evaluate the system on 1,470 subjects pooled across all ADNI phases (CN=1,000, AD=470), where all subjects have sMRI and tabular data, with subsets also having Tau-PET (n=469), fMRI (n=278), and DTI ($n=620$). Pipeline ablation studies across multiple LLM backends show that capable models reach up to 100% intent-parsing accuracy, with the strongest backend (Qwen3.5-27B) reaching 84.8% end-to-end preprocessing step correctness. Automated recovery limits manual intervention to edge cases where human review is required via the Human-In-The-Loop interface. For Alzheimer's Disease classification using automatically preprocessed multimodal data, our agent ensemble achieves an AUC of 0.9518 with four modalities, outperforming all single-modality baselines. These results show that NeuroAgent can reduce the manual effort required for neuroimaging preprocessing and enable end-to-end automated analysis pipelines for neuroimaging research.

Source-Free Domain Adaptation with Vision-Language Prior

Source-Free Domain Adaptation (SFDA) seeks to adapt a source model, which is pre-trained on a supervised source domain, for a target domain, with only access to unlabeled target training data. Relying on pseudo labeling and/or auxiliary supervision, conventional methods are inevitably error-prone. To mitigate this limitation, in this work we for the first time explore the potentials of off-the-shelf vision-language (ViL) multimodal models (e.g., CLIP) with rich whilst heterogeneous knowledge. We find that directly applying the ViL model to the target domain in a zero-shot fashion is unsatisfactory, as it is not specialized for this particular task but largely generic. To make it task-specific, we propose a novel DIFO++ approach. Specifically, DIFO++ alternates between two steps during adaptation: (i) Customizing the ViL model by maximizing the mutual information with the target model in a prompt learning manner, (ii) Distilling the knowledge of this customized ViL model to the target model, centering on gap region reduction. During progressive knowledge adaptation, we first identify and focus on the gap region, where enclosed features are entangled and class-ambiguous, as it often captures richer task-specific semantics. Reliable pseudo-labels are then generated by fusing predictions from the target and ViL models, supported by a memory mechanism. Finally, gap region reduction is guided by category attention and predictive consistency for semantic alignment, complemented by referenced entropy minimization to suppress uncertainty. Extensive experiments show that DIFO++ significantly outperforms the state-of-the-art alternatives. Our code and data are available at https://github.com/tntek/DIFO-Plus.

Immunizing 3D Gaussian Generative Models Against Unauthorized Fine-Tuning via Attribute-Space Traps

Recent large-scale generative models enable high-quality 3D synthesis. However, the public accessibility of pre-trained weights introduces a critical vulnerability. Adversaries can fine-tune these models to steal specialized knowledge acquired during pre-training, leading to intellectual property infringement. Unlike defenses for 2D images and language models, 3D generators require specialized protection due to their explicit Gaussian representations, which expose fundamental structural parameters directly to gradient-based optimization. We propose GaussLock, the first approach designed to defend 3D generative models against fine-tuning attacks. GaussLock is a lightweight parameter-space immunization framework that integrates authorized distillation with attribute-aware trap losses targeting position, scale, rotation, opacity, and color. Specifically, these traps systematically collapse spatial distributions, distort geometric shapes, align rotational axes, and suppress primitive visibility to fundamentally destroy structural integrity. By jointly optimizing these dual objectives, the distillation process preserves fidelity on authorized tasks while the embedded traps actively disrupt unauthorized reconstructions. Experiments on large-scale Gaussian models demonstrate that GaussLock effectively neutralizes unauthorized fine-tuning attacks. It substantially degrades the quality of unauthorized reconstructions, evidenced by significantly higher LPIPS and lower PSNR, while effectively maintaining performance on authorized fine-tuning.

RCP: Representation Consistency Pruner for Mitigating Distribution Shift in Large Vision-Language Models

Large Vision-Language Models (LVLMs) suffer from prohibitive inference costs due to the massive number of visual tokens processed by the language decoder. Existing pruning methods often lead to significant performance degradation because the irreversible removal of visual tokens causes a distribution shift in the hidden states that deviates from the pre-trained full-token regime. To address this, we propose Representation Consistency Pruner, which we refer to as RCP, as a novel framework that integrates cumulative visual token pruning with a delayed repair mechanism. Specifically, we introduce a cross-attention pruner that leverages the intrinsic attention of the LLM as a baseline to predict cumulative masks, ensuring consistent and monotonic token reduction across layers. To compensate for the resulting information loss, we design a delayed repair adapter denoted as DRA, which caches the essence of pruned tokens and applies FiLM-based modulation specifically to the answer generation tokens. We employ a repair loss to match the first and second-order statistics of the pruned representations with a full-token teacher. RCP is highly efficient because it trains only lightweight plug-in modules while allowing for physical token discarding at inference. Extensive experiments on LVLM benchmarks demonstrate that RCP removes up to 88.9\% of visual tokens and reduces FLOPs by up to 85.7\% with only a marginal average accuracy drop, and outperforms prior methods that avoid fine-tuning the original model on several widely used benchmarks.