Advancing COVID-19 Diagnosis with Privacy-Preserving Collaboration in Artificial Intelligence

Artificial intelligence (AI) provides a promising substitution for streamlining COVID-19 diagnoses. However, concerns surrounding security and trustworthiness impede the collection of large-scale representative medical data, posing a considerable challenge for training a well-generalised model in clinical practices. To address this, we launch the Unified CT-COVID AI Diagnostic Initiative (UCADI), where the AI model can be distributedly trained and independently executed at each host institution under a federated learning framework (FL) without data sharing. Here we show that our FL model outperformed all the local models by a large yield (test sensitivity /specificity in China: 0.973/0.951, in the UK: 0.730/0.942), achieving comparable performance with a panel of professional radiologists. We further evaluated the model on the hold-out (collected from another two hospitals leaving out the FL) and heterogeneous (acquired with contrast materials) data, provided visual explanations for decisions made by the model, and analysed the trade-offs between the model performance and the communication costs in the federated training process. Our study is based on 9,573 chest computed tomography scans (CTs) from 3,336 patients collected from 23 hospitals located in China and the UK. Collectively, our work advanced the prospects of utilising federated learning for privacy-preserving AI in digital health.

Harvesting Visual Objects from Internet Images via Deep Learning Based Objectness Assessment

The collection of internet images has been growing in an astonishing speed. It is undoubted that these images contain rich visual information that can be useful in many applications, such as visual media creation and data-driven image synthesis. In this paper, we focus on the methodologies for building a visual object database from a collection of internet images. Such database is built to contain a large number of high-quality visual objects that can help with various data-driven image applications. Our method is based on dense proposal generation and objectness-based re-ranking. A novel deep convolutional neural network is designed for the inference of proposal objectness, the probability of a proposal containing optimally-located foreground object. In our work, the objectness is quantitatively measured in regard of completeness and fullness, reflecting two complementary features of an optimal proposal: a complete foreground and relatively small background. Our experiments indicate that object proposals re-ranked according to the output of our network generally achieve higher performance than those produced by other state-of-the-art methods. As a concrete example, a database of over 1.2 million visual objects has been built using the proposed method, and has been successfully used in various data-driven image applications.