Deep learning techniques have demonstrated great potential for accurately estimating brain age by analyzing Magnetic Resonance Imaging (MRI) data from healthy individuals. However, current methods for brain age estimation often directly utilize whole input images, overlooking two important considerations: 1) the heterogeneous nature of brain aging, where different brain regions may degenerate at different rates, and 2) the existence of age-independent redundancies in brain structure. To overcome these limitations, we propose a Dual Graph Attention based Disentanglement Multi-instance Learning (DGA-DMIL) framework for improving brain age estimation. Specifically, the 3D MRI data, treated as a bag of instances, is fed into a 2D convolutional neural network backbone, to capture the unique aging patterns in MRI. A dual graph attention aggregator is then proposed to learn the backbone features by exploiting the intra- and inter-instance relationships. Furthermore, a disentanglement branch is introduced to separate age-related features from age-independent structural representations to ameliorate the interference of redundant information on age prediction. To verify the effectiveness of the proposed framework, we evaluate it on two datasets, UK Biobank and ADNI, containing a total of 35,388 healthy individuals. Our proposed model demonstrates exceptional accuracy in estimating brain age, achieving a remarkable mean absolute error of 2.12 years in the UK Biobank. The results establish our approach as state-of-the-art compared to other competing brain age estimation models. In addition, the instance contribution scores identify the varied importance of brain areas for aging prediction, which provides deeper insights into the understanding of brain aging.
This paper studies an extremely large-scale reconfigurable intelligent surface (XL-RIS) empowered covert communication system in the near-field region. Alice covertly transmits messages to Bob with the assistance of the XL-RIS, while evading detection by Willie. To enhance the covert communication performance, we maximize the achievable covert rate by jointly optimizing the hybrid analog and digital beamformers at Alice, as well as the reflection coefficient matrix at the XL-RIS. An alternating optimization algorithm is proposed to solve the joint beamforming design problem. For the hybrid beamformer design, a semi-closed-form solution for fully digital beamformer is first obtained by a weighted minimum mean-square error based algorithm, then the baseband digital and analog beamformers at Alice are designed by approximating the fully digital beamformer via manifold optimization. For the XL-RIS's reflection coefficient matrix design, a low-complexity alternating direction method of multipliers based algorithm is proposed to address the challenge of large-scale variables and unit-modulus constraints. Numerical results unveil that i) the near-field communications can achieve a higher covert rate than the far-field covert communications in general, and still realize covert transmission even if Willie is located at the same direction as Bob and closer to the XL-RIS; ii) the proposed algorithm can enhance the covert rate significantly compared to the benchmark schemes; iii) the proposed algorithm leads to a beam diffraction pattern that can bypass Willie and achieve high-rate covert transmission to Bob.
Orthogonal frequency division multiplexing (OFDM)-based integrated sensing and communication (ISAC) is promising for future sixth-generation mobile communication systems. Existing works focus on the joint estimation of the targets' range and velocity for OFDM-based ISAC systems. In contrast, this paper studies the three-dimensional joint estimation (3DJE) of range, velocity, and azimuth for OFDM-based ISAC systems with multiple receive antennas. First, we establish the signal model and derive the Cramer-Rao bounds (CRBs) on the 3DJE. Furthermore, an auto-paired super-resolution 3DJE algorithm is proposed by exploiting the reconstructed observation sub-signal's translational invariance property in the time, frequency, and space domains. Finally, with the 5G New Radio parameter setup, simulation results show that the proposed algorithm achieves better estimation performance and its root mean square error is closer to the root of CRBs than existing methods.
Differentiable physics simulation provides an avenue for tackling previously intractable challenges through gradient-based optimization, thereby greatly improving the efficiency of solving robotics-related problems. To apply differentiable simulation in diverse robotic manipulation scenarios, a key challenge is to integrate various materials in a unified framework. We present SoftMAC, a differentiable simulation framework coupling soft bodies with articulated rigid bodies and clothes. SoftMAC simulates soft bodies with the continuum-mechanics-based Material Point Method (MPM). We provide a forecast-based contact model for MPM, which greatly reduces artifacts like penetration and unnatural rebound. To couple MPM particles with deformable and non-volumetric clothes meshes, we also propose a penetration tracing algorithm that reconstructs the signed distance field in local area. Based on simulators for each modality and the contact model, we develop a differentiable coupling mechanism to simulate the interactions between soft bodies and the other two types of materials. Comprehensive experiments are conducted to validate the effectiveness and accuracy of the proposed differentiable pipeline in downstream robotic manipulation applications. Supplementary materials and videos are available on our project website at https://sites.google.com/view/softmac.
We present Jade, a differentiable physics engine for articulated rigid bodies. Jade models contacts as the Linear Complementarity Problem (LCP). Compared to existing differentiable simulations, Jade offers features including intersection-free collision simulation and stable LCP solutions for multiple frictional contacts. We use continuous collision detection to detect the time of impact and adopt the backtracking strategy to prevent intersection between bodies with complex geometry shapes. We derive the gradient calculation to ensure the whole simulation process is differentiable under the backtracking mechanism. We modify the popular Dantzig algorithm to get valid solutions under multiple frictional contacts. We conduct extensive experiments to demonstrate the effectiveness of our differentiable physics simulation over a variety of contact-rich tasks.
Advanced silicon photonic technologies enable integrated optical sensing and communication (IOSAC) in real time for the emerging application requirements of simultaneous sensing and communication for next-generation networks. Here, we propose and demonstrate the IOSAC system on the silicon nitride (SiN) photonics platform. The IOSAC devices based on microring resonators are capable of monitoring the variation of analytes, transmitting the information to the terminal along with the modulated optical signal in real-time, and replacing bulk optics in high-precision and high-speed applications. By directly integrating SiN ring resonators with optical communication networks, simultaneous sensing and optical communication are demonstrated by an optical signal transmission experimental system using especially filtering amplified spontaneous emission spectra. The refractive index (RI) sensing ring with a sensitivity of 172 nm/RIU, a figure of merit (FOM) of 1220, and a detection limit (DL) of 8.2*10-6 RIU is demonstrated. Simultaneously, the 1.25 Gbps optical on-off-keying (OOK) signal is transmitted at the concentration of different NaCl solutions, which indicates the bit-error-ratio (BER) decreases with the increase in concentration. The novel IOSAC technology shows the potential to realize high-performance simultaneous biosensing and communication in real time and further accelerate the development of IoT and 6G networks.
Hyperspectral image (HSI) denoising is essentially ill-posed since a noisy HSI can be degraded from multiple clean HSIs. However, current deep learning-based approaches ignore this fact and restore the clean image with deterministic mapping (i.e., the network receives a noisy HSI and outputs a clean HSI). To alleviate this issue, this paper proposes a flow-based HSI denoising network (HIDFlowNet) to directly learn the conditional distribution of the clean HSI given the noisy HSI and thus diverse clean HSIs can be sampled from the conditional distribution. Overall, our HIDFlowNet is induced from the flow methodology and contains an invertible decoder and a conditional encoder, which can fully decouple the learning of low-frequency and high-frequency information of HSI. Specifically, the invertible decoder is built by staking a succession of invertible conditional blocks (ICBs) to capture the local high-frequency details since the invertible network is information-lossless. The conditional encoder utilizes down-sampling operations to obtain low-resolution images and uses transformers to capture correlations over a long distance so that global low-frequency information can be effectively extracted. Extensive experimental results on simulated and real HSI datasets verify the superiority of our proposed HIDFlowNet compared with other state-of-the-art methods both quantitatively and visually.
Pan-sharpening aims to generate a high-resolution multispectral (HRMS) image by integrating the spectral information of a low-resolution multispectral (LRMS) image with the texture details of a high-resolution panchromatic (PAN) image. It essentially inherits the ill-posed nature of the super-resolution (SR) task that diverse HRMS images can degrade into an LRMS image. However, existing deep learning-based methods recover only one HRMS image from the LRMS image and PAN image using a deterministic mapping, thus ignoring the diversity of the HRMS image. In this paper, to alleviate this ill-posed issue, we propose a flow-based pan-sharpening network (PanFlowNet) to directly learn the conditional distribution of HRMS image given LRMS image and PAN image instead of learning a deterministic mapping. Specifically, we first transform this unknown conditional distribution into a given Gaussian distribution by an invertible network, and the conditional distribution can thus be explicitly defined. Then, we design an invertible Conditional Affine Coupling Block (CACB) and further build the architecture of PanFlowNet by stacking a series of CACBs. Finally, the PanFlowNet is trained by maximizing the log-likelihood of the conditional distribution given a training set and can then be used to predict diverse HRMS images. The experimental results verify that the proposed PanFlowNet can generate various HRMS images given an LRMS image and a PAN image. Additionally, the experimental results on different kinds of satellite datasets also demonstrate the superiority of our PanFlowNet compared with other state-of-the-art methods both visually and quantitatively.
Glaucoma is a severe blinding disease, for which automatic detection methods are urgently needed to alleviate the scarcity of ophthalmologists. Many works have proposed to employ deep learning methods that involve the segmentation of optic disc and cup for glaucoma detection, in which the segmentation process is often considered merely as an upstream sub-task. The relationship between fundus images and segmentation masks in terms of joint decision-making in glaucoma assessment is rarely explored. We propose a novel segmentation-based information extraction and amalgamation method for the task of glaucoma detection, which leverages the robustness of segmentation masks without disregarding the rich information in the original fundus images. Experimental results on both private and public datasets demonstrate that our proposed method outperforms all models that utilize solely either fundus images or masks.