Eliminating Biased Length Reliance of Direct Preference Optimization via Down-Sampled KL Divergence

Direct Preference Optimization (DPO) has emerged as a prominent algorithm for the direct and robust alignment of Large Language Models (LLMs) with human preferences, offering a more straightforward alternative to the complex Reinforcement Learning from Human Feedback (RLHF). Despite its promising efficacy, DPO faces a notable drawback: "verbosity", a common over-optimization phenomenon also observed in RLHF. While previous studies mainly attributed verbosity to biased labels within the data, we propose that the issue also stems from an inherent algorithmic length reliance in DPO. Specifically, we suggest that the discrepancy between sequence-level Kullback-Leibler (KL) divergences between chosen and rejected sequences, used in DPO, results in overestimated or underestimated rewards due to varying token lengths. Empirically, we utilize datasets with different label lengths to demonstrate the presence of biased rewards. We then introduce an effective downsampling approach, named SamPO, to eliminate potential length reliance. Our experimental evaluations, conducted across three LLMs of varying scales and a diverse array of conditional and open-ended benchmarks, highlight the efficacy of SamPO in mitigating verbosity, achieving improvements of 5% to 12% over DPO through debaised rewards. Our codes can be accessed at: https://github.com/LuJunru/SamPO/.

CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments

The introduction of genome engineering technology has transformed biomedical research, making it possible to make precise changes to genetic information. However, creating an efficient gene-editing system requires a deep understanding of CRISPR technology, and the complex experimental systems under investigation. While Large Language Models (LLMs) have shown promise in various tasks, they often lack specific knowledge and struggle to accurately solve biological design problems. In this work, we introduce CRISPR-GPT, an LLM agent augmented with domain knowledge and external tools to automate and enhance the design process of CRISPR-based gene-editing experiments. CRISPR-GPT leverages the reasoning ability of LLMs to facilitate the process of selecting CRISPR systems, designing guide RNAs, recommending cellular delivery methods, drafting protocols, and designing validation experiments to confirm editing outcomes. We showcase the potential of CRISPR-GPT for assisting non-expert researchers with gene-editing experiments from scratch and validate the agent's effectiveness in a real-world use case. Furthermore, we explore the ethical and regulatory considerations associated with automated gene-editing design, highlighting the need for responsible and transparent use of these tools. Our work aims to bridge the gap between beginner biological researchers and CRISPR genome engineering techniques, and demonstrate the potential of LLM agents in facilitating complex biological discovery tasks.

FIPO: Free-form Instruction-oriented Prompt Optimization with Preference Dataset and Modular Fine-tuning Schema

In the quest to facilitate the deep intelligence of Large Language Models (LLMs) accessible in final-end user-bot interactions, the art of prompt crafting emerges as a critical yet complex task for the average user. Contrast to previous model-oriented yet instruction-agnostic Automatic Prompt Optimization methodologies, yielding polished results for predefined target models while suffering rapid degradation with out-of-box models, we present Free-form Instruction-oriented Prompt Optimization (FIPO). This approach is supported by our large-scale prompt preference dataset and employs a modular fine-tuning schema. The FIPO schema reimagines the optimization process into manageable modules, anchored by a meta prompt that dynamically adapts content. This allows for the flexible integration of the raw task instruction, the optional instruction response, and the optional ground truth to produce finely optimized task prompts. The FIPO preference dataset is meticulously constructed using the optimal and suboptimal LLMs, undergoing rigorous cross-verification by human experts and analytical models. Applying the insights from the data with Tulu2 models and fine-tuning strategies, we validate the efficacy of FIPO schema across five public benchmarks. Codes, data and scripts are here: https://github.com/LuJunru/FIPO_Project.

A Challenger to GPT-4V? Early Explorations of Gemini in Visual Expertise

The surge of interest towards Multi-modal Large Language Models (MLLMs), e.g., GPT-4V(ision) from OpenAI, has marked a significant trend in both academia and industry. They endow Large Language Models (LLMs) with powerful capabilities in visual understanding, enabling them to tackle diverse multi-modal tasks. Very recently, Google released Gemini, its newest and most capable MLLM built from the ground up for multi-modality. In light of the superior reasoning capabilities, can Gemini challenge GPT-4V's leading position in multi-modal learning? In this paper, we present a preliminary exploration of Gemini Pro's visual understanding proficiency, which comprehensively covers four domains: fundamental perception, advanced cognition, challenging vision tasks, and various expert capacities. We compare Gemini Pro with the state-of-the-art GPT-4V to evaluate its upper limits, along with the latest open-sourced MLLM, Sphinx, which reveals the gap between manual efforts and black-box systems. The qualitative samples indicate that, while GPT-4V and Gemini showcase different answering styles and preferences, they can exhibit comparable visual reasoning capabilities, and Sphinx still trails behind them concerning domain generalizability. Specifically, GPT-4V tends to elaborate detailed explanations and intermediate steps, and Gemini prefers to output a direct and concise answer. The quantitative evaluation on the popular MME benchmark also demonstrates the potential of Gemini to be a strong challenger to GPT-4V. Our early investigation of Gemini also observes some common issues of MLLMs, indicating that there still remains a considerable distance towards artificial general intelligence. Our project for tracking the progress of MLLM is released at https://github.com/BradyFU/Awesome-Multimodal-Large-Language-Models.

VKIE: The Application of Key Information Extraction on Video Text

Extracting structured information from videos is critical for numerous downstream applications in the industry. In this paper, we define a significant task of extracting hierarchical key information from visual texts on videos. To fulfill this task, we decouples it into four subtasks and introduce two implementation solutions called PipVKIE and UniVKIE. PipVKIE sequentially completes the four subtasks in continuous stages, while UniVKIE is improved by unifying all the subtasks into one backbone. Both PipVKIE and UniVKIE leverage multimodal information from vision, text, and coordinates for feature representation. Extensive experiments on one well-defined dataset demonstrate that our solutions can achieve remarkable performance and efficient inference speed. The code and dataset will be publicly available.

Rethinking Data Perturbation and Model Stabilization for Semi-supervised Medical Image Segmentation

Studies on semi-supervised medical image segmentation (SSMIS) have seen fast progress recently. Due to the limited labelled data, SSMIS methods mainly focus on effectively leveraging unlabeled data to enhance the segmentation performance. However, despite their promising performance, current state-of-the-art methods often prioritize integrating complex techniques and loss terms rather than addressing the core challenges of semi-supervised scenarios directly. We argue that the key to SSMIS lies in generating substantial and appropriate prediction disagreement on unlabeled data. To this end, we emphasize the crutiality of data perturbation and model stabilization in semi-supervised segmentation, and propose a simple yet effective approach to boost SSMIS performance significantly, dubbed DPMS. Specifically, we first revisit SSMIS from three distinct perspectives: the data, the model, and the loss, and conduct a comprehensive study of corresponding strategies to examine their effectiveness. Based on these examinations, we then propose DPMS, which adopts a plain teacher-student framework with a standard supervised loss and unsupervised consistency loss. To produce appropriate prediction disagreements, DPMS perturbs the unlabeled data via strong augmentations to enlarge prediction disagreements considerably. On the other hand, using EMA teacher when strong augmentation is applied does not necessarily improve performance. DPMS further utilizes a forwarding-twice and momentum updating strategies for normalization statistics to stabilize the training on unlabeled data effectively. Despite its simplicity, DPMS can obtain new state-of-the-art performance on the public 2D ACDC and 3D LA datasets across various semi-supervised settings, e.g. obtaining a remarkable 22.62% improvement against previous SOTA on ACDC with 5% labels.

MemoChat: Tuning LLMs to Use Memos for Consistent Long-Range Open-Domain Conversation

We propose MemoChat, a pipeline for refining instructions that enables large language models (LLMs) to effectively employ self-composed memos for maintaining consistent long-range open-domain conversations. We demonstrate a long-range open-domain conversation through iterative "memorization-retrieval-response" cycles. This requires us to carefully design tailored tuning instructions for each distinct stage. The instructions are reconstructed from a collection of public datasets to teach the LLMs to memorize and retrieve past dialogues with structured memos, leading to enhanced consistency when participating in future conversations. We invite experts to manually annotate a test set designed to evaluate the consistency of long-range conversations questions. Experiments on three testing scenarios involving both open-source and API-accessible chatbots at scale verify the efficacy of MemoChat, which outperforms strong baselines. Our codes, data and models are available here: https://github.com/LuJunru/MemoChat.

Grafting Pre-trained Models for Multimodal Headline Generation

Multimodal headline utilizes both video frames and transcripts to generate the natural language title of the videos. Due to a lack of large-scale, manually annotated data, the task of annotating grounded headlines for video is labor intensive and impractical. Previous researches on pre-trained language models and video-language models have achieved significant progress in related downstream tasks. However, none of them can be directly applied to multimodal headline architecture where we need both multimodal encoder and sentence decoder. A major challenge in simply gluing language model and video-language model is the modality balance, which is aimed at combining visual-language complementary abilities. In this paper, we propose a novel approach to graft the video encoder from the pre-trained video-language model on the generative pre-trained language model. We also present a consensus fusion mechanism for the integration of different components, via inter/intra modality relation. Empirically, experiments show that the grafted model achieves strong results on a brand-new dataset collected from real-world applications.

Unsupervised Extractive Summarization with Heterogeneous Graph Embeddings for Chinese Document

In the scenario of unsupervised extractive summarization, learning high-quality sentence representations is essential to select salient sentences from the input document. Previous studies focus more on employing statistical approaches or pre-trained language models (PLMs) to extract sentence embeddings, while ignoring the rich information inherent in the heterogeneous types of interaction between words and sentences. In this paper, we are the first to propose an unsupervised extractive summarizaiton method with heterogeneous graph embeddings (HGEs) for Chinese document. A heterogeneous text graph is constructed to capture different granularities of interactions by incorporating graph structural information. Moreover, our proposed graph is general and flexible where additional nodes such as keywords can be easily integrated. Experimental results demonstrate that our method consistently outperforms the strong baseline in three summarization datasets.

Leveraging Key Information Modeling to Improve Less-Data Constrained News Headline Generation via Duality Fine-Tuning

Recent language generative models are mostly trained on large-scale datasets, while in some real scenarios, the training datasets are often expensive to obtain and would be small-scale. In this paper we investigate the challenging task of less-data constrained generation, especially when the generated news headlines are short yet expected by readers to keep readable and informative simultaneously. We highlight the key information modeling task and propose a novel duality fine-tuning method by formally defining the probabilistic duality constraints between key information prediction and headline generation tasks. The proposed method can capture more information from limited data, build connections between separate tasks, and is suitable for less-data constrained generation tasks. Furthermore, the method can leverage various pre-trained generative regimes, e.g., autoregressive and encoder-decoder models. We conduct extensive experiments to demonstrate that our method is effective and efficient to achieve improved performance in terms of language modeling metric and informativeness correctness metric on two public datasets.