Weighted Knowledge Distillation for Semi-Supervised Segmentation of Maxillary Sinus in Panoramic X-ray Images

Accurate segmentation of maxillary sinus in panoramic X-ray images is essential for dental diagnosis and surgical planning; however, this task remains relatively underexplored in dental imaging research. Structural overlap, ambiguous anatomical boundaries inherent to two-dimensional panoramic projections, and the limited availability of large scale clinical datasets with reliable pixel-level annotations make the development and evaluation of segmentation models challenging. To address these challenges, we propose a semi-supervised segmentation framework that effectively leverages both labeled and unlabeled panoramic radiographs, where knowledge distillation is utilized to train a student model with reliable structural information distilled from a teacher model. Specifically, we introduce a weighted knowledge distillation loss to suppress unreliable distillation signals caused by structural discrepancies between teacher and student predictions. To further enhance the quality of pseudo labels generated by the teacher network, we introduce SinusCycle-GAN which is a refinement network based on unpaired image-to-image translation. This refinement process improves the precision of boundaries and reduces noise propagation when learning from unlabeled data during semi-supervised training. To evaluate the proposed method, we collected clinical panoramic X-ray images from 2,511 patients, and experimental results demonstrate that the proposed method outperforms state-of-the-art segmentation models, achieving the Dice score of 96.35\% while reducing boundary error. The results indicate that the proposed semi-supervised framework provides robust and anatomically consistent segmentation performance under limited labeled data conditions, highlighting its potential for broader dental image analysis applications.

Centering Ecological Goals in Automated Identification of Individual Animals

Recognizing individual animals over time is central to many ecological and conservation questions, including estimating abundance, survival, movement, and social structure. Recent advances in automated identification from images and even acoustic data suggest that this process could be greatly accelerated, yet their promise has not translated well into ecological practice. We argue that the main barrier is not the performance of the automated methods themselves, but a mismatch between how those methods are typically developed and evaluated, and how ecological data is actually collected, processed, reviewed, and used. Future progress, therefore, will depend less on algorithmic gains alone than on recognizing that the usefulness of automated identification is grounded in ecological context: it depends on what question is being asked, what data are available, and what kinds of mistakes matter. Only by centering these questions can we move toward automated identification of individuals that is not only accurate but also ecologically useful, transparent, and trustworthy.

Harmonizing MR Images Across 100+ Scanners: Multi-site Validation with Traveling Subjects and Real-world Protocols

Reliable harmonization of heterogeneous magnetic resonance~(MR) image datasets, especially those acquired in pragmatic clinical trials, is critical to advance multi-center neuroimaging studies and translational machine learning in healthcare. We present an enhanced and rigorously validated version of the HACA3 harmonization algorithm, which we refer to as HACA3$^+$, incorporating key methodological enhancements: (1)~an improved artifact encoder to better isolate and mitigate image artifacts, (2)~background and foreground-sensitive attention mechanisms to increase harmonization specificity, and (3)~extensive training using data spanning 100+ scanners from 64 independent sites, providing a broader diversity of scanners than other harmonization methods. Our study focuses on four commonly acquired MR image contrasts (T1-weighted, T2-weighted, proton density, \& fluid-attenuated inversion recovery), reflecting realistic clinical protocols. We perform inter-site harmonization experiments using traveling subjects to assess the generalization and robustness of the harmonization model. We compare the results of the publicly available version of HACA3 and our implementation, HACA3$^+$. Downstream relevance is further established through whole brain segmentation and image imputation. Finally, we justify each enhancement through an ablation experiment. Pre-trained weights and code for HACA3$^+$ are made publicly available at https://github.com/shays15/haca3-plus.

Wan-Image: Pushing the Boundaries of Generative Visual Intelligence

We present Wan-Image, a unified visual generation system explicitly engineered to paradigm-shift image generation models from casual synthesizers into professional-grade productivity tools. While contemporary diffusion models excel at aesthetic generation, they frequently encounter critical bottlenecks in rigorous design workflows that demand absolute controllability, complex typography rendering, and strict identity preservation. To address these challenges, Wan-Image features a natively unified multi-modal architecture by synergizing the cognitive capabilities of large language models with the high-fidelity pixel synthesis of diffusion transformers, which seamlessly translates highly nuanced user intents into precise visual outputs. It is fundamentally powered by large-scale multi-modal data scaling, a systematic fine-grained annotation engine, and curated reinforcement learning data to surpass basic instruction following and unlock expert-level professional capabilities. These include ultra-long complex text rendering, hyper-diverse portrait generation, palette-guided generation, multi-subject identity preservation, coherent sequential visual generation, precise multi-modal interactive editing, native alpha-channel generation, and high-efficiency 4K synthesis. Across diverse human evaluations, Wan-Image exceeds Seedream 5.0 Lite and GPT Image 1.5 in overall performance, reaching parity with Nano Banana Pro in challenging tasks. Ultimately, Wan-Image revolutionizes visual content creation across e-commerce, entertainment, education, and personal productivity, redefining the boundaries of professional visual synthesis.

Medical Image Understanding Improves Survival Prediction via Visual Instruction Tuning

Accurate prognostication and risk estimation are essential for guiding clinical decision-making and optimizing patient management. While radiologist-assessed features from CT scans provide valuable indicators of disease severity and outcomes, interpreting such images requires expert knowledge, and translating rich visual information into textual summaries inevitably leads to information loss. In this work, we propose a vision-language framework for 3D CT image understanding that leverages large-scale open-sourced CT images paired with radiology reports through visual instruction tuning. This pre-training enables the model to learn clinically meaningful visual-textual representations, which can then be adapted to downstream survival prediction tasks. By incorporating a survival prediction head on top of the pre-trained model, our approach improves survival prediction from CT images and clinical data while generating clinically meaningful language responses to predefined questions. Experimental results demonstrate that our method outperforms baseline methods in survival prediction, particularly, when clinical data alone is less predictive. The code will be released upon acceptance.

REVEAL: Multimodal Vision-Language Alignment of Retinal Morphometry and Clinical Risks for Incident AD and Dementia Prediction

The retina provides a unique, noninvasive window into Alzheimer's disease (AD) and dementia, capturing early structural changes through morphometric features, while systemic and lifestyle risk factors reflect well-established contributors to disease susceptibility long before clinical symptom onset. However, current retinal analysis frameworks typically model imaging and risk factors separately, limiting their ability to capture joint multimodal patterns critical for early risk prediction. Moreover, existing methods rarely incorporate mechanisms to organize or align patients with similar retinal and clinical characteristics, constraining the learning of coherent cross-modal associations. To address these limitations, we introduce REVEAL (REtinal-risk Vision-Language Early Alzheimer's Learning), a framework that aligns color fundus photographs with individualized disease-specific risk profiles for predicting incident AD and dementia, on average 8 years before diagnosis (range: 1-11 years). Because real-world risk factors are structured questionnaire data, we translate them into clinically interpretable narratives compatible with pretrained vision-language models (VLMs). We further propose a group-aware contrastive learning (GACL) strategy that clusters patients with similar retinal morphometry and risk factors as positive pairs, strengthening multimodal alignment. This unified representation learning framework substantially outperforms state-of-the-art retinal imaging models paired with clinical text encoders, as well as general-purpose VLMs, demonstrating the value of jointly modeling retinal biomarkers and clinical risk factors. By providing a generalizable and noninvasive approach for early AD and dementia risk stratification, REVEAL has the potential to enable earlier intervention and improve preventive care at the population level.

Image-to-Image Translation Framework Embedded with Rotation Symmetry Priors

Image-to-image translation (I2I) is a fundamental task in computer vision, focused on mapping an input image from a source domain to a corresponding image in a target domain while preserving domain-invariant features and adapting domain-specific attributes. Despite the remarkable success of deep learning-based I2I approaches, the lack of paired data and unsupervised learning framework still hinder their effectiveness. In this work, we address the challenge by incorporating transformation symmetry priors into image-to-image translation networks. Specifically, we introduce rotation group equivariant convolutions to achieve rotation equivariant I2I framework, a novel contribution, to the best of our knowledge, along this research direction. This design ensures the preservation of rotation symmetry, one of the most intrinsic and domain-invariant properties of natural and scientific images, throughout the network. Furthermore, we conduct a systematic study on image symmetry priors on real dataset and propose a novel transformation learnable equivariant convolutions (TL-Conv) that adaptively learns transformation groups, enhancing symmetry preservation across diverse datasets. We also provide a theoretical analysis of the equivariance error of TL-Conv, proving that it maintains exact equivariance in continuous domains and provide a bound for the error in discrete cases. Through extensive experiments across a range of I2I tasks, we validate the effectiveness and superior performance of our approach, highlighting the potential of equivariant networks in enhancing generation quality and its broad applicability. Our code is available at https://github.com/tanfy929/Equivariant-I2I

Cycle-Consistent Search: Question Reconstructability as a Proxy Reward for Search Agent Training

Reinforcement Learning (RL) has shown strong potential for optimizing search agents in complex information retrieval tasks. However, existing approaches predominantly rely on gold supervision, such as ground-truth answers, which is difficult to scale. To address this limitation, we propose Cycle-Consistent Search (CCS), a gold-supervision-free framework for training search agents, inspired by cycle-consistency techniques from unsupervised machine translation and image-to-image translation. Our key hypothesis is that an optimal search trajectory, unlike insufficient or irrelevant ones, serves as a lossless encoding of the question's intent. Consequently, a high-quality trajectory should preserve the information required to accurately reconstruct the original question, thereby inducing a reward signal for policy optimization. However, naive cycle-consistency objectives are vulnerable to information leakage, as reconstruction may rely on superficial lexical cues rather than the underlying search process. To reduce this effect, we apply information bottlenecks, including exclusion of the final response and named entity recognition (NER) masking of search queries. These constraints force reconstruction to rely on retrieved observations together with the structural scaffold, ensuring that the resulting reward signal reflects informational adequacy rather than linguistic redundancy. Experiments on question-answering benchmarks show that CCS achieves performance comparable to supervised baselines while outperforming prior methods that do not rely on gold supervision. These results suggest that CCS provides a scalable training paradigm for training search agents in settings where gold supervision is unavailable.

VGGT-Segmentor: Geometry-Enhanced Cross-View Segmentation

Instance-level object segmentation across disparate egocentric and exocentric views is a fundamental challenge in visual understanding, critical for applications in embodied AI and remote collaboration. This task is exceptionally difficult due to severe changes in scale, perspective, and occlusion, which destabilize direct pixel-level matching. While recent geometry-aware models like VGGT provide a strong foundation for feature alignment, we find they often fail at dense prediction tasks due to significant pixel-level projection drift, even when their internal object-level attention remains consistent. To bridge this gap, we introduce VGGT-Segmentor (VGGT-S), a framework that unifies robust geometric modeling with pixel-accurate semantic segmentation. VGGT-S leverages VGGT's powerful cross-view feature representation and introduces a novel Union Segmentation Head. This head operates in three stages: mask prompt fusion, point-guided prediction, and iterative mask refinement, effectively translating high-level feature alignment into a precise segmentation mask. Furthermore, we propose a single-image self-supervised training strategy that eliminates the need for paired annotations and enables strong generalization. On the Ego-Exo4D benchmark, VGGT-S sets a new state-of-the-art, achieving 67.7% and 68.0% average IoU for Ego to Exo and Exo to Ego tasks, respectively, significantly outperforming prior methods. Notably, our correspondence-free pretrained model surpasses most fully-supervised baselines, demonstrating the effectiveness and scalability of our approach.

VibeFlow: Versatile Video Chroma-Lux Editing through Self-Supervised Learning

Video chroma-lux editing, which aims to modify illumination and color while preserving structural and temporal fidelity, remains a significant challenge. Existing methods typically rely on expensive supervised training with synthetic paired data. This paper proposes VibeFlow, a novel self-supervised framework that unleashes the intrinsic physical understanding of pre-trained video generation models. Instead of learning color and light transitions from scratch, we introduce a disentangled data perturbation pipeline that enforces the model to adaptively recombine structure from source videos and color-illumination cues from reference images, enabling robust disentanglement in a self-supervised manner. Furthermore, to rectify discretization errors inherent in flow-based models, we introduce Residual Velocity Fields alongside a Structural Distortion Consistency Regularization, ensuring rigorous structural preservation and temporal coherence. Our framework eliminates the need for costly training resources and generalizes in a zero-shot manner to diverse applications, including video relighting, recoloring, low-light enhancement, day-night translation, and object-specific color editing. Extensive experiments demonstrate that VibeFlow achieves impressive visual quality with significantly reduced computational overhead. Our project is publicly available at https://lyf1212.github.io/VibeFlow-webpage.