Cross Modality Image Translation In Medical Imaging Using Generative Frameworks

Medical image-to-image (I2I) translation enables virtual scanning, i.e. the synthesis of a target imaging modality from a source one without additional acquisitions. Despite growing interest, most proposed methods operate on 2D slices, are evaluated on isolated tasks with different experimental set-ups and lack clinical validation. The primary contribution of this work is a reproducible, standardized comparative evaluation of 3D I2I translation methods in oncological imaging, designed to standardize preprocessing, splitting, inference, and multi-level evaluation across heterogeneous clinical tasks. Within this framework, we compare seven generative models, three Generative Adversarial Networks (GANs: Pix2Pix, CycleGAN, SRGAN) and four latent generative models (Latent Diffusion Model, Latent Diffusion Model+ControlNet, Brownian Bridge, Flow Matching), across eleven datasets spanning three anatomical regions (head/neck, lung, pelvis) and four translation directions (cone-beam CT to CT, MRI to CT, CT to PET, MRI T2-weighted to T2-FLAIR), for a total of 77 experiments under uniform training, inference, and evaluation conditions. The results show that GANs outperform latent generative models across all tasks, with SRGAN achieving statistically significant superiority. Our lesion-level analysis reveals that all models struggle with small lesions and that, in CT to PET synthesis, models reproduce lesion shape more reliably than absolute uptake-related intensity. We also performed a Visual Turing test administered to 17 physicians, including 15 radiologists, which shows near-chance classification accuracy (56.7%), confirming that synthetic volumes are largely indistinguishable from real acquisitions, while exposing a dissociation between quantitative metrics and clinical preference.

Breaking Dual Bottlenecks: Evolving Unified Multimodal Models into Self-Adaptive Interleaved Visual Reasoners

Recent unified models integrate multimodal understanding and generation within a single framework. However, an "understanding-generation gap" persists, where models can capture user intent but often fail to translate this semantic knowledge into precise pixel-level manipulation. This gap results in two bottlenecks in anything-to-image task (X2I): the attention entanglement bottleneck, where blind planning struggles with complex prompts, and the visual refinement bottleneck, where unstructured feedback fails to correct imperfections efficiently. In this paper, we propose a novel framework that empowers unified models to autonomously switch between generation strategies based on instruction complexity and model capability. To achieve this, we construct a hierarchical data pipeline that constructs execution paths across three adaptive modes: direct generation for simple cases, self-reflection for quality refinement, and multi-step planning for decomposing complex scenarios. Building on this pipeline, we contribute a high-quality dataset with over 50,000 samples and implement a two-stage training strategy comprising SFT and RL. Specifically, we design step-wise reasoning rewards to ensure logical consistency and intra-group complexity penalty to prevent redundant computational overhead. Extensive experiments demonstrate that our method outperforms existing baselines on X2I, achieving superior generation fidelity among simple-to-complex instructions. The code is released at https://github.com/WeChatCV/Interleaved_Visual_Reasoner.

MechVerse: Evaluating Physical Motion Consistency in Video Generation Models

Text- and image-conditioned video generation models have achieved strong visual fidelity and temporal coherence, but they often fail to generate motion governed by kinematic and geometric constraints. In these settings, object parts must remain rigid, maintain contact or coupling with neighboring components, and transfer motion consistently across connected parts. These requirements are especially explicit in articulated mechanical assemblies, where motion is constrained by rigid-link geometry, contact/coupling relations, and transmission through kinematic chains. A generated video may therefore appear plausible while violating the intended mechanism, such as rotating a part that should translate, deforming a rigid component, breaking coupling between parts, or failing to move downstream components. To evaluate this gap, We introduce MechVerse, a benchmark for mechanically consistent image-to-video generation. MechVerse contains 21,156 synthetic clips from 1,357 mechanical assemblies across 141 categories, organized into three tiers of increasing kinematic complexity: independent articulation, pairwise coupling, and densely coupled multi-part mechanisms. Each clip is paired with a structured prompt describing part identities, stationary supports, moving components, motion primitives, direction, speed/extent, and inter-part dependencies. We evaluate proprietary, open-source, and fine-tuned image-to-video models using standard video metrics, instruction-following scores, and human judgments of motion correctness and kinematic coupling. Results show that current models can preserve appearance and smoothness while failing to generate mechanically admissible motion, with errors increasing as coupling complexity grows. MechVerse provides a benchmark for measuring and improving mechanism-aware video generation from image and language inputs.

Fixed-Point Neural Optimal Transport without Implicit Differentiation

We propose an implicit neural formulation of optimal transport that eliminates adversarial min--max optimization and multi-network architectures commonly used in existing approaches. Our key idea is to parameterize a single potential in the Kantorovich dual and reformulate the associated c-transform as a proximal fixed-point problem. This yields a stable single-network framework in which dual feasibility is enforced exactly through proximal optimality conditions rather than adversarial training. Despite the inner fixed-point computation, gradients can be computed without differentiating through the fixed-point iterations, enabling efficient training without requiring implicit differentiation. We further establish convergence of stochastic gradient descent. The resulting framework is efficient, scalable, and broadly applicable: it simultaneously recovers forward and backward transport maps and naturally extends to class-conditional settings. Experiments on high-dimensional Gaussian benchmarks, physical datasets, and image translation tasks demonstrate strong transport accuracy together with improved training stability and favorable computational and memory efficiency.

Checkup2Action: A Multimodal Clinical Check-up Report Dataset for Patient-Oriented Action Card Generation

Clinical check-up reports are multimodal documents that combine page layouts, tables, numerical biomarkers, abnormality flags, imaging findings, and domain-specific terminology. Such heterogeneous evidence is difficult for laypersons to interpret and translate into concrete follow-up actions. Although large language models show promise in medical summarisation and triage support, their ability to generate safe, prioritised, and patient-oriented actions from multimodal check-up reports remains under-benchmarked. We present \textbf{Checkup2Action}, a multimodal clinical check-up report dataset and benchmark for structured \textit{Action Card} generation. Each card describes one clinically relevant issue and specifies its priority, recommended department, follow-up time window, patient-facing explanation, and questions for clinicians, while avoiding diagnostic or treatment-prescriptive claims. The dataset contains 2,000 de-identified real-world check-up reports covering demographic information, physical examinations, laboratory tests, cardiovascular assessments, and imaging-related evidence. We formulate checkup-to-action generation as a constrained structured generation task and introduce an evaluation protocol covering issue coverage and precision, priority consistency, department and time recommendation accuracy, action complexity, usefulness, readability, and safety compliance. Experiments with general-purpose and medical large language models reveal clear trade-offs between issue coverage, action correctness, conciseness, and safety alignment. Checkup2Action provides a new multimodal benchmark for evaluating patient-oriented reasoning over clinical check-up reports.

KamonBench: A Grammar-Based Dataset for Evaluating Compositional Factor Recovery in Vision-Language Models

Kamon (family crests) are an important part of Japanese culture and a natural test case for compositional visual recognition: each crest combines a small number of symbolic choices, but the space of possible descriptions is sparse. We introduce KamonBench, a grammar-based image-to-structure benchmark with 20,000 synthetic composite crests and auxiliary component examples. Each composite crest is paired with a formal kamon description language - "kamon yōgo" - description, a segmented Japanese analysis, an English translation, and a non-linguistic program code. Because each synthetic crest is generated from known factors, namely container, modifier, and motif, KamonBench supports evaluation beyond caption-level accuracy: direct program-code factor metrics, controlled factor-pair recombination splits, counterfactual motif-sensitivity groups under fixed container-modifier contexts, and linear probes of factor accessibility. We include baseline results for a ViT encoder/Transformer decoder and two VGG n-gram decoders, with and without learned positional masks. KamonBench therefore provides a controlled testbed for sparse compositional visual recognition and factor recovery in vision-language models.

DBMSolver: A Training-free Diffusion Bridge Sampler for High-Quality Image-to-Image Translation

Diffusion-based image-to-image (I2I) translation excels in high-fidelity generation but suffers from slow sampling in state-of-the-art Diffusion Bridge Models (DBMs), often requiring dozens of function evaluations (NFEs). We introduce DBMSolver, a training-free sampler that exploits the semi-linear structure of DBM's underlying SDE and ODE via exponential integrators, yielding highly-efficient 1st- and 2nd-order solutions. This reduces NFEs by up to 5x while boosting quality (e.g., FID drops 53% on DIODE at 20 NFEs vs. 2nd-order baseline). Experiments on inpainting, stylization, and semantics-to-image tasks across resolutions up to 256x256 show DBMSolver sets new SOTA efficiency-quality tradeoffs, enabling real-world applicability. Our code is publicly available at https://github.com/snumprlab/dbmsolver.

SenseNova-U1: Unifying Multimodal Understanding and Generation with NEO-unify Architecture

Recent large vision-language models (VLMs) remain fundamentally constrained by a persistent dichotomy: understanding and generation are treated as distinct problems, leading to fragmented architectures, cascaded pipelines, and misaligned representation spaces. We argue that this divide is not merely an engineering artifact, but a structural limitation that hinders the emergence of native multimodal intelligence. Hence, we introduce SenseNova-U1, a native unified multimodal paradigm built upon NEO-unify, in which understanding and generation evolve as synergistic views of a single underlying process. We launch two native unified variants, SenseNova-U1-8B-MoT and SenseNova-U1-A3B-MoT, built on dense (8B) and mixture-of-experts (30B-A3B) understanding baselines, respectively. Designed from first principles, they rival top-tier understanding-only VLMs across text understanding, vision-language perception, knowledge reasoning, agentic decision-making, and spatial intelligence. Meanwhile, they deliver strong semantic consistency and visual fidelity, excelling in conventional or knowledge-intensive any-to-image (X2I) synthesis, complex text-rich infographic generation, and interleaved vision-language generation, with or without think patterns. Beyond performance, we show detailed model design, data preprocessing, pre-/post-training, and inference strategies to support community research. Last but not least, preliminary evidence demonstrates that our models extend beyond perception and generation, performing strongly in vision-language-action (VLA) and world model (WM) scenarios. This points toward a broader roadmap where models do not translate between modalities, but think and act across them in a native manner. Multimodal AI is no longer about connecting separate systems, but about building a unified one and trusting the necessary capabilities to emerge from within.

STAGE: Tackling Semantic Drift in Multimodal Federated Graph Learning

Federated graph learning (FGL) enables collaborative training on graph data across multiple clients. As graph data increasingly contain multimodal node attributes such as text and images, multimodal federated graph learning (MM-FGL) has become an important yet substantially harder setting. The key challenge is that clients from different modality domains may not share a common semantic space: even for the same concept, their local encoders can produce inconsistent representations before collaboration begins. This makes direct parameter coordination unreliable and further causes two downstream problems: forcing heterogeneous client representations into a naively shared semantic space may create false semantic agreement, and graph message passing may amplify residual inconsistency across neighborhoods. To address this issue, we propose \textbf{STAGE}, a protocol-first framework for MM-FGL. Instead of relying on direct parameter averaging, STAGE builds a shared semantic space that first translates heterogeneous multimodal features into comparable representations and then regulates how these representations propagate over local graph structures. In this way, STAGE not only improves cross-client semantic calibration, but also reduces the risk of inconsistency amplification during graph learning. Extensive experiments on 8 multimodal-attributed graphs across 5 graph-centric and modality-centric tasks show that STAGE consistently achieves state-of-the-art performance while reducing per-round communication payload.

Spectral Transformer Neural Processes

Time series, spatial data, and images are natural applications of Neural Processes. However, when such data exhibit strong periodicity and quasi-periodicity, existing methods often suffer from underfitting and generalise poorly beyond the training distribution. In this work, we propose Spectral Transformer Neural Processes (STNPs), a frequency-aware extension of Transformer Neural Processes (TNPs). STNPs introduce a Spectral Aggregator that estimates an empirical context spectrum, compresses it into a spectral mixture, samples task-adaptive spectral features, and concatenates them with time-domain embeddings, thereby injecting a spectral-mixture-kernel bias into TNPs. This design reshapes the similarity geometry, allowing inputs that are distant in Euclidean space to remain close in an induced periodic manifold while enhancing time-frequency interactions. Extensive experiments on synthetic regression tasks, real-world time-series datasets, and an image dataset demonstrate that STNPs consistently improve predictive performance over existing baselines, extending Neural Processes beyond translation equivariance towards effective modelling of periodicity and quasi-periodicity.