BBQ-to-Image: Numeric Bounding Box and Qolor Control in Large-Scale Text-to-Image Models

Text-to-image models have rapidly advanced in realism and controllability, with recent approaches leveraging long, detailed captions to support fine-grained generation. However, a fundamental parametric gap remains: existing models rely on descriptive language, whereas professional workflows require precise numeric control over object location, size, and color. In this work, we introduce BBQ, a large-scale text-to-image model that directly conditions on numeric bounding boxes and RGB triplets within a unified structured-text framework. We obtain precise spatial and chromatic control by training on captions enriched with parametric annotations, without architectural modifications or inference-time optimization. This also enables intuitive user interfaces such as object dragging and color pickers, replacing ambiguous iterative prompting with precise, familiar controls. Across comprehensive evaluations, BBQ achieves strong box alignment and improves RGB color fidelity over state-of-the-art baselines. More broadly, our results support a new paradigm in which user intent is translated into an intermediate structured language, consumed by a flow-based transformer acting as a renderer and naturally accommodating numeric parameters.

Imaging-Derived Coronary Fractional Flow Reserve: Advances in Physics-Based, Machine-Learning, and Physics-Informed Methods

Purpose of Review Imaging derived fractional flow reserve (FFR) is rapidly evolving beyond conventional computational fluid dynamics (CFD) based pipelines toward machine learning (ML), deep learning (DL), and physics informed approaches that enable fast, wire free, and scalable functional assessment of coronary stenosis. This review synthesizes recent advances in CT and angiography based FFR, with particular emphasis on emerging physics informed neural networks and neural operators (PINNs and PINOs) and key considerations for their clinical translation. Recent Findings ML/DL approaches have markedly improved automation and computational speed, enabling prediction of pressure and FFR from anatomical descriptors or angiographic contrast dynamics. However, their real-world performance and generalizability can remain variable and sensitive to domain shift, due to multi-center heterogeneity, interpretability challenges, and differences in acquisition protocols and image quality. Physics informed learning introduces conservation structure and boundary condition consistency into model training, improving generalizability and reducing dependence on dense supervision while maintaining rapid inference. Recent evaluation trends increasingly highlight deployment oriented metrics, including calibration, uncertainty quantification, and quality control gatekeeping, as essential for safe clinical use. Summary The field is converging toward imaging derived FFR methods that are faster, more automated, and more reliable. While ML/DL offers substantial efficiency gains, physics informed frameworks such as PINNs and PINOs may provide a more robust balance between speed and physical consistency. Prospective multi center validation and standardized evaluation will be critical to support broad and safe clinical adoption.

Statistical Opportunities in Neuroimaging

Neuroimaging has profoundly enhanced our understanding of the human brain by characterizing its structure, function, and connectivity through modalities like MRI, fMRI, EEG, and PET. These technologies have enabled major breakthroughs across the lifespan, from early brain development to neurodegenerative and neuropsychiatric disorders. Despite these advances, the brain is a complex, multiscale system, and neuroimaging measurements are correspondingly high-dimensional. This creates major statistical challenges, including measurement noise, motion-related artifacts, substantial inter-subject and site/scanner variability, and the sheer scale of modern studies. This paper explores statistical opportunities and challenges in neuroimaging across four key areas: (i) brain development from birth to age 20, (ii) the adult and aging brain, (iii) neurodegeneration and neuropsychiatric disorders, and (iv) brain encoding and decoding. After a quick tutorial on major imaging technologies, we review cutting-edge studies, underscore data and modeling challenges, and highlight research opportunities for statisticians. We conclude by emphasizing that close collaboration among statisticians, neuroscientists, and clinicians is essential for translating neuroimaging advances into improved diagnostics, deeper mechanistic insight, and more personalized treatments.

Towards reconstructing experimental sparse-view X-ray CT data with diffusion models

Diffusion-based image generators are promising priors for ill-posed inverse problems like sparse-view X-ray Computed Tomography (CT). As most studies consider synthetic data, it is not clear whether training data mismatch (``domain shift'') or forward model mismatch complicate their successful application to experimental data. We measured CT data from a physical phantom resembling the synthetic Shepp-Logan phantom and trained diffusion priors on synthetic image data sets with different degrees of domain shift towards it. Then, we employed the priors in a Decomposed Diffusion Sampling scheme on sparse-view CT data sets with increasing difficulty leading to the experimental data. Our results reveal that domain shift plays a nuanced role: while severe mismatch causes model collapse and hallucinations, diverse priors outperform well-matched but narrow priors. Forward model mismatch pulls the image samples away from the prior manifold, which causes artifacts but can be mitigated with annealed likelihood schedules that also increase computational efficiency. Overall, we demonstrate that performance gains do not immediately translate from synthetic to experimental data, and future development must validate against real-world benchmarks.

SCAR: Satellite Imagery-Based Calibration for Aerial Recordings

We introduce SCAR, a method for long-term auto-calibration refinement of aerial visual-inertial systems that exploits georeferenced satellite imagery as a persistent global reference. SCAR estimates both intrinsic and extrinsic parameters by aligning aerial images with 2D--3D correspondences derived from publicly available orthophotos and elevation models. In contrast to existing approaches that rely on dedicated calibration maneuvers or manually surveyed ground control points, our method leverages external geospatial data to detect and correct calibration degradation under field deployment conditions. We evaluate our approach on six large-scale aerial campaigns conducted over two years under diverse seasonal and environmental conditions. Across all sequences, SCAR consistently outperforms established baselines (Kalibr, COLMAP, VINS-Mono), reducing median reprojection error by a large margin, and translating these calibration gains into substantially lower visual localization rotation errors and higher pose accuracy. These results demonstrate that SCAR provides accurate, robust, and reproducible calibration over long-term aerial operations without the need for manual intervention.

DCDM: Divide-and-Conquer Diffusion Models for Consistency-Preserving Video Generation

Recent video generative models have demonstrated impressive visual fidelity, yet they often struggle with semantic, geometric, and identity consistency. In this paper, we propose a system-level framework, termed the Divide-and-Conquer Diffusion Model (DCDM), to address three key challenges: (1) intra-clip world knowledge consistency, (2) inter-clip camera consistency, and (3) inter-shot element consistency. DCDM decomposes video consistency modeling under these scenarios into three dedicated components while sharing a unified video generation backbone. For intra-clip consistency, DCDM leverages a large language model to parse input prompts into structured semantic representations, which are subsequently translated into coherent video content by a diffusion transformer. For inter-clip camera consistency, we propose a temporal camera representation in the noise space that enables precise and stable camera motion control, along with a text-to-image initialization mechanism to further enhance controllability. For inter-shot consistency, DCDM adopts a holistic scene generation paradigm with windowed cross-attention and sparse inter-shot self-attention, ensuring long-range narrative coherence while maintaining computational efficiency. We validate our framework on the test set of the CVM Competition at AAAI'26, and the results demonstrate that the proposed strategies effectively address these challenges.

OmniCT: Towards a Unified Slice-Volume LVLM for Comprehensive CT Analysis

Computed Tomography (CT) is one of the most widely used and diagnostically information-dense imaging modalities, covering critical organs such as the heart, lungs, liver, and colon. Clinical interpretation relies on both slice-driven local features (e.g., sub-centimeter nodules, lesion boundaries) and volume-driven spatial representations (e.g., tumor infiltration, inter-organ anatomical relations). However, existing Large Vision-Language Models (LVLMs) remain fragmented in CT slice versus volumetric understanding: slice-driven LVLMs show strong generalization but lack cross-slice spatial consistency, while volume-driven LVLMs explicitly capture volumetric semantics but suffer from coarse granularity and poor compatibility with slice inputs. The absence of a unified modeling paradigm constitutes a major bottleneck for the clinical translation of medical LVLMs. We present OmniCT, a powerful unified slice-volume LVLM for CT scenarios, which makes three contributions: (i) Spatial Consistency Enhancement (SCE): volumetric slice composition combined with tri-axial positional embedding that introduces volumetric consistency, and an MoE hybrid projection enables efficient slice-volume adaptation; (ii) Organ-level Semantic Enhancement (OSE): segmentation and ROI localization explicitly align anatomical regions, emphasizing lesion- and organ-level semantics; (iii) MedEval-CT: the largest slice-volume CT dataset and hybrid benchmark integrates comprehensive metrics for unified evaluation. OmniCT consistently outperforms existing methods with a substantial margin across diverse clinical tasks and satisfies both micro-level detail sensitivity and macro-level spatial reasoning. More importantly, it establishes a new paradigm for cross-modal medical imaging understanding.

Understanding Image2Video Domain Shift in Food Segmentation: An Instance-level Analysis on Apples

Food segmentation models trained on static images have achieved strong performance on benchmark datasets; however, their reliability in video settings remains poorly understood. In real-world applications such as food monitoring and instance counting, segmentation outputs must be temporally consistent, yet image-trained models often break down when deployed on videos. In this work, we analyze this failure through an instance segmentation and tracking perspective, focusing on apples as a representative food category. Models are trained solely on image-level food segmentation data and evaluated on video sequences using an instance segmentation with tracking-by-matching framework, enabling object-level temporal analysis. Our results reveal that high frame-wise segmentation accuracy does not translate to stable instance identities over time. Temporal appearance variations, particularly illumination changes, specular reflections, and texture ambiguity, lead to mask flickering and identity fragmentation, resulting in significant errors in apple counting. These failures are largely overlooked by conventional image-based metrics, which substantially overestimate real-world video performance. Beyond diagnosing the problem, we examine practical remedies that do not require full video supervision, including post-hoc temporal regularization and self-supervised temporal consistency objectives. Our findings suggest that the root cause of failure lies in image-centric training objectives that ignore temporal coherence, rather than model capacity. This study highlights a critical evaluation gap in food segmentation research and motivates temporally-aware learning and evaluation protocols for video-based food analysis.

Benchmarking the Effects of Object Pose Estimation and Reconstruction on Robotic Grasping Success

3D reconstruction serves as the foundational layer for numerous robotic perception tasks, including 6D object pose estimation and grasp pose generation. Modern 3D reconstruction methods for objects can produce visually and geometrically impressive meshes from multi-view images, yet standard geometric evaluations do not reflect how reconstruction quality influences downstream tasks such as robotic manipulation performance. This paper addresses this gap by introducing a large-scale, physics-based benchmark that evaluates 6D pose estimators and 3D mesh models based on their functional efficacy in grasping. We analyze the impact of model fidelity by generating grasps on various reconstructed 3D meshes and executing them on the ground-truth model, simulating how grasp poses generated with an imperfect model affect interaction with the real object. This assesses the combined impact of pose error, grasp robustness, and geometric inaccuracies from 3D reconstruction. Our results show that reconstruction artifacts significantly decrease the number of grasp pose candidates but have a negligible effect on grasping performance given an accurately estimated pose. Our results also reveal that the relationship between grasp success and pose error is dominated by spatial error, and even a simple translation error provides insight into the success of the grasping pose of symmetric objects. This work provides insight into how perception systems relate to object manipulation using robots.

Finite-time Stable Pose Estimation on TSE(3) using Point Cloud and Velocity Sensors

This work presents a finite-time stable pose estimator (FTS-PE) for rigid bodies undergoing rotational and translational motion in three dimensions, using measurements from onboard sensors that provide position vectors to inertially-fixed points and body velocities. The FTS-PE is a full-state observer for the pose (position and orientation) and velocities and is obtained through a Lyapunov analysis that shows its stability in finite time and its robustness to bounded measurement noise. Further, this observer is designed directly on the state space, the tangent bundle of the Lie group of rigid body motions, SE(3), without using local coordinates or (dual) quaternion representations. Therefore, it can estimate arbitrary rigid body motions without encountering singularities or the unwinding phenomenon and be readily applied to autonomous vehicles. A version of this observer that does not need translational velocity measurements and uses only point clouds and angular velocity measurements from rate gyros, is also obtained. It is discretized using the framework of geometric mechanics for numerical and experimental implementations. The numerical simulations compare the FTS-PE with a dual-quaternion extended Kalman filter and our previously developed variational pose estimator (VPE). The experimental results are obtained using point cloud images and rate gyro measurements obtained from a Zed 2i stereo depth camera sensor. These results validate the stability and robustness of the FTS-PE.