Image-to-image translation is the process of converting an image from one domain to another using deep learning techniques.
Accurate localization is essential for autonomous vehicles, yet sensor noise and drift over time can lead to significant pose estimation errors, particularly in long-horizon environments. A common strategy for correcting accumulated error is visual loop closure in SLAM, which adjusts the pose graph when the agent revisits previously mapped locations. These techniques typically rely on identifying visual mappings between the current view and previously observed scenes and often require fusing data from multiple sensors. In contrast, this work introduces NeRF-Assisted 3D-3D Pose Alignment (NAP3D), a complementary approach that leverages 3D-3D correspondences between the agent's current depth image and a pre-trained Neural Radiance Field (NeRF). By directly aligning 3D points from the observed scene with synthesized points from the NeRF, NAP3D refines the estimated pose even from novel viewpoints, without relying on revisiting previously observed locations. This robust 3D-3D formulation provides advantages over conventional 2D-3D localization methods while remaining comparable in accuracy and applicability. Experiments demonstrate that NAP3D achieves camera pose correction within 5 cm on a custom dataset, robustly outperforming a 2D-3D Perspective-N-Point baseline. On TUM RGB-D, NAP3D consistently improves 3D alignment RMSE by approximately 6 cm compared to this baseline given varying noise, despite PnP achieving lower raw rotation and translation parameter error in some regimes, highlighting NAP3D's improved geometric consistency in 3D space. By providing a lightweight, dataset-agnostic tool, NAP3D complements existing SLAM and localization pipelines when traditional loop closure is unavailable.
Recovering high-fidelity 3D images from sparse or degraded 2D images is a fundamental challenge in medical imaging, with broad applications ranging from 3D ultrasound reconstruction to MRI super-resolution. In the context of fetal MRI, high-resolution 3D reconstruction of the brain from motion-corrupted low-resolution 2D acquisitions is a prerequisite for accurate neurodevelopmental diagnosis. While implicit neural representations (INRs) have recently established state-of-the-art performance in self-supervised slice-to-volume reconstruction (SVR), they suffer from a critical computational bottleneck: accurately modeling the image acquisition physics requires expensive stochastic Monte Carlo sampling to approximate the point spread function (PSF). In this work, we propose a shift from neural network based implicit representations to Gaussian based explicit representations. By parameterizing the HR 3D image volume as a field of anisotropic Gaussian primitives, we leverage the property of Gaussians being closed under convolution and thus derive a \textit{closed-form analytical solution} for the forward model. This formulation reduces the previously intractable acquisition integral to an exact covariance addition ($\mathbfΣ_{obs} = \mathbfΣ_{HR} + \mathbfΣ_{PSF}$), effectively bypassing the need for compute-intensive stochastic sampling while ensuring exact gradient propagation. We demonstrate that our approach matches the reconstruction quality of self-supervised state-of-the-art SVR frameworks while delivering a 5$\times$--10$\times$ speed-up on neonatal and fetal data. With convergence often reached in under 30 seconds, our framework paves the way towards translation into clinical routine of real-time fetal 3D MRI. Code will be public at {https://github.com/m-dannecker/Gaussian-Primitives-for-Fast-SVR}.




Our aim is to develop a unified model for sign language understanding, that performs sign language translation (SLT) and sign-subtitle alignment (SSA). Together, these two tasks enable the conversion of continuous signing videos into spoken language text and also the temporal alignment of signing with subtitles -- both essential for practical communication, large-scale corpus construction, and educational applications. To achieve this, our approach is built upon three components: (i) a lightweight visual backbone that captures manual and non-manual cues from human keypoints and lip-region images while preserving signer privacy; (ii) a Sliding Perceiver mapping network that aggregates consecutive visual features into word-level embeddings to bridge the vision-text gap; and (iii) a multi-task scalable training strategy that jointly optimises SLT and SSA, reinforcing both linguistic and temporal alignment. To promote cross-linguistic generalisation, we pretrain our model on large-scale sign-text corpora covering British Sign Language (BSL) and American Sign Language (ASL) from the BOBSL and YouTube-SL-25 datasets. With this multilingual pretraining and strong model design, we achieve state-of-the-art results on the challenging BOBSL (BSL) dataset for both SLT and SSA. Our model also demonstrates robust zero-shot generalisation and finetuned SLT performance on How2Sign (ASL), highlighting the potential of scalable translation across different sign languages.
Deep learning holds immense promise for transforming medical image analysis, yet its clinical generalization remains profoundly limited. A major barrier is data heterogeneity. This is particularly true in Magnetic Resonance Imaging, where scanner hardware differences, diverse acquisition protocols, and varying sequence parameters introduce substantial domain shifts that obscure underlying biological signals. Data harmonization methods aim to reduce these instrumental and acquisition variability, but existing approaches remain insufficient. When applied to imaging data, image-based harmonization approaches are often restricted by the need for target images, while existing text-guided methods rely on simplistic labels that fail to capture complex acquisition details or are typically restricted to datasets with limited variability, failing to capture the heterogeneity of real-world clinical environments. To address these limitations, we propose DIST-CLIP (Disentangled Style Transfer with CLIP Guidance), a unified framework for MRI harmonization that flexibly uses either target images or DICOM metadata for guidance. Our framework explicitly disentangles anatomical content from image contrast, with the contrast representations being extracted using pre-trained CLIP encoders. These contrast embeddings are then integrated into the anatomical content via a novel Adaptive Style Transfer module. We trained and evaluated DIST-CLIP on diverse real-world clinical datasets, and showed significant improvements in performance when compared against state-of-the-art methods in both style translation fidelity and anatomical preservation, offering a flexible solution for style transfer and standardizing MRI data. Our code and weights will be made publicly available upon publication.
Embodied agents operating in open environments must translate high-level instructions into grounded, executable behaviors, often requiring coordinated use of both hands. While recent foundation models offer strong semantic reasoning, existing robotic task planners remain predominantly unimanual and fail to address the spatial, geometric, and coordination challenges inherent to bimanual manipulation in scene-agnostic settings. We present a unified framework for scene-agnostic bimanual task planning that bridges high-level reasoning with 3D-grounded two-handed execution. Our approach integrates three key modules. Visual Point Grounding (VPG) analyzes a single scene image to detect relevant objects and generate world-aligned interaction points. Bimanual Subgoal Planner (BSP) reasons over spatial adjacency and cross-object accessibility to produce compact, motion-neutralized subgoals that exploit opportunities for coordinated two-handed actions. Interaction-Point-Driven Bimanual Prompting (IPBP) binds these subgoals to a structured skill library, instantiating synchronized unimanual or bimanual action sequences that satisfy hand-state and affordance constraints. Together, these modules enable agents to plan semantically meaningful, physically feasible, and parallelizable two-handed behaviors in cluttered, previously unseen scenes. Experiments show that it produces coherent, feasible, and compact two-handed plans, and generalizes to cluttered scenes without retraining, demonstrating robust scene-agnostic affordance reasoning for bimanual tasks.




GUI grounding, which translates natural language instructions into precise pixel coordinates, is essential for developing practical GUI agents. However, we observe that existing grounding models exhibit significant coordinate prediction instability, minor visual perturbations (e.g. cropping a few pixels) can drastically alter predictions, flipping results between correct and incorrect. This instability severely undermines model performance, especially for samples with high-resolution and small UI elements. To address this issue, we propose Multi-View Prediction (MVP), a training-free framework that enhances grounding performance through multi-view inference. Our key insight is that while single-view predictions may be unstable, aggregating predictions from multiple carefully cropped views can effectively distinguish correct coordinates from outliers. MVP comprises two components: (1) Attention-Guided View Proposal, which derives diverse views guided by instruction-to-image attention scores, and (2) Multi-Coordinates Clustering, which ensembles predictions by selecting the centroid of the densest spatial cluster. Extensive experiments demonstrate MVP's effectiveness across various models and benchmarks. Notably, on ScreenSpot-Pro, MVP boosts UI-TARS-1.5-7B to 56.1%, GTA1-7B to 61.7%, Qwen3VL-8B-Instruct to 65.3%, and Qwen3VL-32B-Instruct to 74.0%. The code is available at https://github.com/ZJUSCL/MVP.
Magnetic Resonance Imaging (MRI) diagnoses and manages a wide range of diseases, yet long scan times drive high costs and limit accessibility. AI methods have demonstrated substantial potential for reducing scan times, but despite rapid progress, clinical translation of AI often fails. One particular class of failure modes, referred to as implicit data crimes, are a result of hidden biases introduced when MRI datasets incompletely model the MRI physics of the acquisition. Previous work identified data crimes resulting from algorithmic completion of k-space with parallel imaging and drew on simulation to demonstrate the resulting downstream biases. This work proposes a mathematical framework to re-characterize the problem as one of error reduction during interpolation between sets of evaluation coordinates. We establish a generalized matrix-based definition of the reconstruction error upper bound as a function of the input sampling pattern. Experiments on relevant sampling pattern structures demonstrate the relevance of the framework and suggest future directions for analysis of data crimes.
Quantitative Susceptibility Mapping (QSM) quantifies tissue magnetic susceptibility from magnetic-resonance phase data and plays a crucial role in brain microstructure imaging, iron-deposition assessment, and neurological-disease research. However, single-orientation QSM inversion remains highly ill-posed because the dipole kernel exhibits a cone-null region in the Fourier domain, leading to streaking artifacts and structural loss. To overcome this limitation, we propose QSMnet-INR, a deep, physics-informed framework that integrates an Implicit Neural Representation (INR) into the k-space domain. The INR module continuously models multi-directional dipole responses and explicitly completes the cone-null region, while a frequency-domain residual-weighted Dipole Loss enforces physical consistency. The overall network combines a 3D U-Net-based QSMnet backbone with the INR module through alternating optimization for end-to-end joint training. Experiments on the 2016 QSM Reconstruction Challenge, a multi-orientation GRE dataset, and both in-house and public single-orientation clinical data demonstrate that QSMnet-INR consistently outperforms conventional and recent deep-learning approaches across multiple quantitative metrics. The proposed framework shows notable advantages in structural recovery within cone-null regions and in artifact suppression. Ablation studies further confirm the complementary contributions of the INR module and Dipole Loss to detail preservation and physical stability. Overall, QSMnet-INR effectively alleviates the ill-posedness of single-orientation QSM without requiring multi-orientation acquisition, achieving high accuracy, robustness, and strong cross-scenario generalization-highlighting its potential for clinical translation.
Ultrasound offers a radiation-free, cost-effective solution for real-time visualization of spinal landmarks, paraspinal soft tissues and neurovascular structures, making it valuable for intraoperative guidance during spinal procedures. However, ultrasound suffers from inherent limitations in visualizing complete vertebral anatomy, in particular vertebral bodies, due to acoustic shadowing effects caused by bone. In this work, we present a novel multi-modal deep learning method for completing occluded anatomical structures in 3D ultrasound by leveraging complementary information from a single X-ray image. To enable training, we generate paired training data consisting of: (1) 2D lateral vertebral views that simulate X-ray scans, and (2) 3D partial vertebrae representations that mimic the limited visibility and occlusions encountered during ultrasound spine imaging. Our method integrates morphological information from both imaging modalities and demonstrates significant improvements in vertebral reconstruction (p < 0.001) compared to state of art in 3D ultrasound vertebral completion. We perform phantom studies as an initial step to future clinical translation, and achieve a more accurate, complete volumetric lumbar spine visualization overlayed on the ultrasound scan without the need for registration with preoperative modalities such as computed tomography. This demonstrates that integrating a single X-ray projection mitigates ultrasound's key limitation while preserving its strengths as the primary imaging modality. Code and data can be found at https://github.com/miruna20/US-X-Complete




Embodied world models aim to predict and interact with the physical world through visual observations and actions. However, existing models struggle to accurately translate low-level actions (e.g., joint positions) into precise robotic movements in predicted frames, leading to inconsistencies with real-world physical interactions. To address these limitations, we propose MTV-World, an embodied world model that introduces Multi-view Trajectory-Video control for precise visuomotor prediction. Specifically, instead of directly using low-level actions for control, we employ trajectory videos obtained through camera intrinsic and extrinsic parameters and Cartesian-space transformation as control signals. However, projecting 3D raw actions onto 2D images inevitably causes a loss of spatial information, making a single view insufficient for accurate interaction modeling. To overcome this, we introduce a multi-view framework that compensates for spatial information loss and ensures high-consistency with physical world. MTV-World forecasts future frames based on multi-view trajectory videos as input and conditioning on an initial frame per view. Furthermore, to systematically evaluate both robotic motion precision and object interaction accuracy, we develop an auto-evaluation pipeline leveraging multimodal large models and referring video object segmentation models. To measure spatial consistency, we formulate it as an object location matching problem and adopt the Jaccard Index as the evaluation metric. Extensive experiments demonstrate that MTV-World achieves precise control execution and accurate physical interaction modeling in complex dual-arm scenarios.