CATformer: Contrastive Adversarial Transformer for Image Super-Resolution

Super-resolution remains a promising technique to enhance the quality of low-resolution images. This study introduces CATformer (Contrastive Adversarial Transformer), a novel neural network integrating diffusion-inspired feature refinement with adversarial and contrastive learning. CATformer employs a dual-branch architecture combining a primary diffusion-inspired transformer, which progressively refines latent representations, with an auxiliary transformer branch designed to enhance robustness to noise through learned latent contrasts. These complementary representations are fused and decoded using deep Residual-in-Residual Dense Blocks for enhanced reconstruction quality. Extensive experiments on benchmark datasets demonstrate that CATformer outperforms recent transformer-based and diffusion-inspired methods both in efficiency and visual image quality. This work bridges the performance gap among transformer-, diffusion-, and GAN-based methods, laying a foundation for practical applications of diffusion-inspired transformers in super-resolution.

A holistic perception system of internal and external monitoring for ground autonomous vehicles: AutoTRUST paradigm

This paper introduces a holistic perception system for internal and external monitoring of autonomous vehicles, with the aim of demonstrating a novel AI-leveraged self-adaptive framework of advanced vehicle technologies and solutions that optimize perception and experience on-board. Internal monitoring system relies on a multi-camera setup designed for predicting and identifying driver and occupant behavior through facial recognition, exploiting in addition a large language model as virtual assistant. Moreover, the in-cabin monitoring system includes AI-empowered smart sensors that measure air-quality and perform thermal comfort analysis for efficient on and off-boarding. On the other hand, external monitoring system perceives the surrounding environment of vehicle, through a LiDAR-based cost-efficient semantic segmentation approach, that performs highly accurate and efficient super-resolution on low-quality raw 3D point clouds. The holistic perception framework is developed in the context of EU's Horizon Europe programm AutoTRUST, and has been integrated and deployed on a real electric vehicle provided by ALKE. Experimental validation and evaluation at the integration site of Joint Research Centre at Ispra, Italy, highlights increased performance and efficiency of the modular blocks of the proposed perception architecture.

TinySR: Pruning Diffusion for Real-World Image Super-Resolution

Real-world image super-resolution (Real-ISR) focuses on recovering high-quality images from low-resolution inputs that suffer from complex degradations like noise, blur, and compression. Recently, diffusion models (DMs) have shown great potential in this area by leveraging strong generative priors to restore fine details. However, their iterative denoising process incurs high computational overhead, posing challenges for real-time applications. Although one-step distillation methods, such as OSEDiff and TSD-SR, offer faster inference, they remain fundamentally constrained by their large, over-parameterized model architectures. In this work, we present TinySR, a compact yet effective diffusion model specifically designed for Real-ISR that achieves real-time performance while maintaining perceptual quality. We introduce a Dynamic Inter-block Activation and an Expansion-Corrosion Strategy to facilitate more effective decision-making in depth pruning. We achieve VAE compression through channel pruning, attention removal and lightweight SepConv. We eliminate time- and prompt-related modules and perform pre-caching techniques to further speed up the model. TinySR significantly reduces computational cost and model size, achieving up to 5.68x speedup and 83% parameter reduction compared to its teacher TSD-SR, while still providing high quality results.

Neural Proteomics Fields for Super-resolved Spatial Proteomics Prediction

Spatial proteomics maps protein distributions in tissues, providing transformative insights for life sciences. However, current sequencing-based technologies suffer from low spatial resolution, and substantial inter-tissue variability in protein expression further compromises the performance of existing molecular data prediction methods. In this work, we introduce the novel task of spatial super-resolution for sequencing-based spatial proteomics (seq-SP) and, to the best of our knowledge, propose the first deep learning model for this task--Neural Proteomics Fields (NPF). NPF formulates seq-SP as a protein reconstruction problem in continuous space by training a dedicated network for each tissue. The model comprises a Spatial Modeling Module, which learns tissue-specific protein spatial distributions, and a Morphology Modeling Module, which extracts tissue-specific morphological features. Furthermore, to facilitate rigorous evaluation, we establish an open-source benchmark dataset, Pseudo-Visium SP, for this task. Experimental results demonstrate that NPF achieves state-of-the-art performance with fewer learnable parameters, underscoring its potential for advancing spatial proteomics research. Our code and dataset are publicly available at https://github.com/Bokai-Zhao/NPF.

Structural Damage Detection Using AI Super Resolution and Visual Language Model

Natural disasters pose significant challenges to timely and accurate damage assessment due to their sudden onset and the extensive areas they affect. Traditional assessment methods are often labor-intensive, costly, and hazardous to personnel, making them impractical for rapid response, especially in resource-limited settings. This study proposes a novel, cost-effective framework that leverages aerial drone footage, an advanced AI-based video super-resolution model, Video Restoration Transformer (VRT), and Gemma3:27b, a 27 billion parameter Visual Language Model (VLM). This integrated system is designed to improve low-resolution disaster footage, identify structural damage, and classify buildings into four damage categories, ranging from no/slight damage to total destruction, along with associated risk levels. The methodology was validated using pre- and post-event drone imagery from the 2023 Turkey earthquakes (courtesy of The Guardian) and satellite data from the 2013 Moore Tornado (xBD dataset). The framework achieved a classification accuracy of 84.5%, demonstrating its ability to provide highly accurate results. Furthermore, the system's accessibility allows non-technical users to perform preliminary analyses, thereby improving the responsiveness and efficiency of disaster management efforts.

HiCache: Training-free Acceleration of Diffusion Models via Hermite Polynomial-based Feature Caching

Diffusion models have achieved remarkable success in content generation but suffer from prohibitive computational costs due to iterative sampling. While recent feature caching methods tend to accelerate inference through temporal extrapolation, these methods still suffer from server quality loss due to the failure in modeling the complex dynamics of feature evolution. To solve this problem, this paper presents HiCache, a training-free acceleration framework that fundamentally improves feature prediction by aligning mathematical tools with empirical properties. Our key insight is that feature derivative approximations in Diffusion Transformers exhibit multivariate Gaussian characteristics, motivating the use of Hermite polynomials-the potentially theoretically optimal basis for Gaussian-correlated processes. Besides, We further introduce a dual-scaling mechanism that ensures numerical stability while preserving predictive accuracy. Extensive experiments demonstrate HiCache's superiority: achieving 6.24x speedup on FLUX.1-dev while exceeding baseline quality, maintaining strong performance across text-to-image, video generation, and super-resolution tasks. Core implementation is provided in the appendix, with complete code to be released upon acceptance.

Zero-shot Volumetric CT Super-Resolution using 3D Gaussian Splatting with Upsampled 2D X-ray Projection Priors

Computed tomography (CT) is widely used in clinical diagnosis, but acquiring high-resolution (HR) CT is limited by radiation exposure risks. Deep learning-based super-resolution (SR) methods have been studied to reconstruct HR from low-resolution (LR) inputs. While supervised SR approaches have shown promising results, they require large-scale paired LR-HR volume datasets that are often unavailable. In contrast, zero-shot methods alleviate the need for paired data by using only a single LR input, but typically struggle to recover fine anatomical details due to limited internal information. To overcome these, we propose a novel zero-shot 3D CT SR framework that leverages upsampled 2D X-ray projection priors generated by a diffusion model. Exploiting the abundance of HR 2D X-ray data, we train a diffusion model on large-scale 2D X-ray projection and introduce a per-projection adaptive sampling strategy. It selects the generative process for each projection, thus providing HR projections as strong external priors for 3D CT reconstruction. These projections serve as inputs to 3D Gaussian splatting for reconstructing a 3D CT volume. Furthermore, we propose negative alpha blending (NAB-GS) that allows negative values in Gaussian density representation. NAB-GS enables residual learning between LR and diffusion-based projections, thereby enhancing high-frequency structure reconstruction. Experiments on two datasets show that our method achieves superior quantitative and qualitative results for 3D CT SR.

Potential and challenges of generative adversarial networks for super-resolution in 4D Flow MRI

4D Flow Magnetic Resonance Imaging (4D Flow MRI) enables non-invasive quantification of blood flow and hemodynamic parameters. However, its clinical application is limited by low spatial resolution and noise, particularly affecting near-wall velocity measurements. Machine learning-based super-resolution has shown promise in addressing these limitations, but challenges remain, not least in recovering near-wall velocities. Generative adversarial networks (GANs) offer a compelling solution, having demonstrated strong capabilities in restoring sharp boundaries in non-medical super-resolution tasks. Yet, their application in 4D Flow MRI remains unexplored, with implementation challenged by known issues such as training instability and non-convergence. In this study, we investigate GAN-based super-resolution in 4D Flow MRI. Training and validation were conducted using patient-specific cerebrovascular in-silico models, converted into synthetic images via an MR-true reconstruction pipeline. A dedicated GAN architecture was implemented and evaluated across three adversarial loss functions: Vanilla, Relativistic, and Wasserstein. Our results demonstrate that the proposed GAN improved near-wall velocity recovery compared to a non-adversarial reference (vNRMSE: 6.9% vs. 9.6%); however, that implementation specifics are critical for stable network training. While Vanilla and Relativistic GANs proved unstable compared to generator-only training (vNRMSE: 8.1% and 7.8% vs. 7.2%), a Wasserstein GAN demonstrated optimal stability and incremental improvement (vNRMSE: 6.9% vs. 7.2%). The Wasserstein GAN further outperformed the generator-only baseline at low SNR (vNRMSE: 8.7% vs. 10.7%). These findings highlight the potential of GAN-based super-resolution in enhancing 4D Flow MRI, particularly in challenging cerebrovascular regions, while emphasizing the need for careful selection of adversarial strategies.

Img2ST-Net: Efficient High-Resolution Spatial Omics Prediction from Whole Slide Histology Images via Fully Convolutional Image-to-Image Learning

Recent advances in multi-modal AI have demonstrated promising potential for generating the currently expensive spatial transcriptomics (ST) data directly from routine histology images, offering a means to reduce the high cost and time-intensive nature of ST data acquisition. However, the increasing resolution of ST, particularly with platforms such as Visium HD achieving 8um or finer, introduces significant computational and modeling challenges. Conventional spot-by-spot sequential regression frameworks become inefficient and unstable at this scale, while the inherent extreme sparsity and low expression levels of high-resolution ST further complicate both prediction and evaluation. To address these limitations, we propose Img2ST-Net, a novel histology-to-ST generation framework for efficient and parallel high-resolution ST prediction. Unlike conventional spot-by-spot inference methods, Img2ST-Net employs a fully convolutional architecture to generate dense, HD gene expression maps in a parallelized manner. By modeling HD ST data as super-pixel representations, the task is reformulated from image-to-omics inference into a super-content image generation problem with hundreds or thousands of output channels. This design not only improves computational efficiency but also better preserves the spatial organization intrinsic to spatial omics data. To enhance robustness under sparse expression patterns, we further introduce SSIM-ST, a structural-similarity-based evaluation metric tailored for high-resolution ST analysis. We present a scalable, biologically coherent framework for high-resolution ST prediction. Img2ST-Net offers a principled solution for efficient and accurate ST inference at scale. Our contributions lay the groundwork for next-generation ST modeling that is robust and resolution-aware. The source code has been made publicly available at https://github.com/hrlblab/Img2ST-Net.

SNNSIR: A Simple Spiking Neural Network for Stereo Image Restoration

Spiking Neural Networks (SNNs), characterized by discrete binary activations, offer high computational efficiency and low energy consumption, making them well-suited for computation-intensive tasks such as stereo image restoration. In this work, we propose SNNSIR, a simple yet effective Spiking Neural Network for Stereo Image Restoration, specifically designed under the spike-driven paradigm where neurons transmit information through sparse, event-based binary spikes. In contrast to existing hybrid SNN-ANN models that still rely on operations such as floating-point matrix division or exponentiation, which are incompatible with the binary and event-driven nature of SNNs, our proposed SNNSIR adopts a fully spike-driven architecture to achieve low-power and hardware-friendly computation. To address the expressiveness limitations of binary spiking neurons, we first introduce a lightweight Spike Residual Basic Block (SRBB) to enhance information flow via spike-compatible residual learning. Building on this, the Spike Stereo Convolutional Modulation (SSCM) module introduces simplified nonlinearity through element-wise multiplication and highlights noise-sensitive regions via cross-view-aware modulation. Complementing this, the Spike Stereo Cross-Attention (SSCA) module further improves stereo correspondence by enabling efficient bidirectional feature interaction across views within a spike-compatible framework. Extensive experiments on diverse stereo image restoration tasks, including rain streak removal, raindrop removal, low-light enhancement, and super-resolution demonstrate that our model achieves competitive restoration performance while significantly reducing computational overhead. These results highlight the potential for real-time, low-power stereo vision applications. The code will be available after the article is accepted.