LLM Novice Uplift on Dual-Use, In Silico Biology Tasks

Large language models (LLMs) perform increasingly well on biology benchmarks, but it remains unclear whether they uplift novice users -- i.e., enable humans to perform better than with internet-only resources. This uncertainty is central to understanding both scientific acceleration and dual-use risk. We conducted a multi-model, multi-benchmark human uplift study comparing novices with LLM access versus internet-only access across eight biosecurity-relevant task sets. Participants worked on complex problems with ample time (up to 13 hours for the most involved tasks). We found that LLM access provided substantial uplift: novices with LLMs were 4.16 times more accurate than controls (95% CI [2.63, 6.87]). On four benchmarks with available expert baselines (internet-only), novices with LLMs outperformed experts on three of them. Perhaps surprisingly, standalone LLMs often exceeded LLM-assisted novices, indicating that users were not eliciting the strongest available contributions from the LLMs. Most participants (89.6%) reported little difficulty obtaining dual-use-relevant information despite safeguards. Overall, LLMs substantially uplift novices on biological tasks previously reserved for trained practitioners, underscoring the need for sustained, interactive uplift evaluations alongside traditional benchmarks.

Efficient Tail-Aware Generative Optimization via Flow Model Fine-Tuning

Fine-tuning pre-trained diffusion and flow models to optimize downstream utilities is central to real-world deployment. Existing entropy-regularized methods primarily maximize expected reward, providing no mechanism to shape tail behavior. However, tail control is often essential: the lower tail determines reliability by limiting low-reward failures, while the upper tail enables discovery by prioritizing rare, high-reward outcomes. In this work, we present Tail-aware Flow Fine-Tuning (TFFT), a principled and efficient distributional fine-tuning algorithm based on the Conditional Value-at-Risk (CVaR). We address two distinct tail-shaping goals: right-CVaR for seeking novel samples in the high-reward tail and left-CVaR for controlling worst-case samples in the low-reward tail. Unlike prior approaches that rely on non-linear optimization, we leverage the variational dual formulation of CVaR to decompose it into a decoupled two-stage procedure: a lightweight one-dimensional threshold optimization step, and a single entropy-regularized fine-tuning process via a specific pseudo-reward. This decomposition achieves CVaR fine-tuning efficiently with computational cost comparable to standard expected fine-tuning methods. We demonstrate the effectiveness of TFFT across illustrative experiments, high-dimensional text-to-image generation, and molecular design.

MeshMimic: Geometry-Aware Humanoid Motion Learning through 3D Scene Reconstruction

Humanoid motion control has witnessed significant breakthroughs in recent years, with deep reinforcement learning (RL) emerging as a primary catalyst for achieving complex, human-like behaviors. However, the high dimensionality and intricate dynamics of humanoid robots make manual motion design impractical, leading to a heavy reliance on expensive motion capture (MoCap) data. These datasets are not only costly to acquire but also frequently lack the necessary geometric context of the surrounding physical environment. Consequently, existing motion synthesis frameworks often suffer from a decoupling of motion and scene, resulting in physical inconsistencies such as contact slippage or mesh penetration during terrain-aware tasks. In this work, we present MeshMimic, an innovative framework that bridges 3D scene reconstruction and embodied intelligence to enable humanoid robots to learn coupled "motion-terrain" interactions directly from video. By leveraging state-of-the-art 3D vision models, our framework precisely segments and reconstructs both human trajectories and the underlying 3D geometry of terrains and objects. We introduce an optimization algorithm based on kinematic consistency to extract high-quality motion data from noisy visual reconstructions, alongside a contact-invariant retargeting method that transfers human-environment interaction features to the humanoid agent. Experimental results demonstrate that MeshMimic achieves robust, highly dynamic performance across diverse and challenging terrains. Our approach proves that a low-cost pipeline utilizing only consumer-grade monocular sensors can facilitate the training of complex physical interactions, offering a scalable path toward the autonomous evolution of humanoid robots in unstructured environments.

Efficient UAV trajectory prediction: A multi-modal deep diffusion framework

To meet the requirements for managing unauthorized UAVs in the low-altitude economy, a multi-modal UAV trajectory prediction method based on the fusion of LiDAR and millimeter-wave radar information is proposed. A deep fusion network for multi-modal UAV trajectory prediction, termed the Multi-Modal Deep Fusion Framework, is designed. The overall architecture consists of two modality-specific feature extraction networks and a bidirectional cross-attention fusion module, aiming to fully exploit the complementary information of LiDAR and radar point clouds in spatial geometric structure and dynamic reflection characteristics. In the feature extraction stage, the model employs independent but structurally identical feature encoders for LiDAR and radar. After feature extraction, the model enters the Bidirectional Cross-Attention Mechanism stage to achieve information complementarity and semantic alignment between the two modalities. To verify the effectiveness of the proposed model, the MMAUD dataset used in the CVPR 2024 UG2+ UAV Tracking and Pose-Estimation Challenge is adopted as the training and testing dataset. Experimental results show that the proposed multi-modal fusion model significantly improves trajectory prediction accuracy, achieving a 40% improvement compared to the baseline model. In addition, ablation experiments are conducted to demonstrate the effectiveness of different loss functions and post-processing strategies in improving model performance. The proposed model can effectively utilize multi-modal data and provides an efficient solution for unauthorized UAV trajectory prediction in the low-altitude economy.

Dynamic Channel Charting: An LSTM-AE-based Approach

With the development of the sixth-generation (6G) communication system, Channel State Information (CSI) plays a crucial role in improving network performance. Traditional Channel Charting (CC) methods map high-dimensional CSI data to low-dimensional spaces to help reveal the geometric structure of wireless channels. However, most existing CC methods focus on learning static geometric structures and ignore the dynamic nature of the channel over time, leading to instability and poor topological consistency of the channel charting in complex environments. To address this issue, this paper proposes a novel time-series channel charting approach based on the integration of Long Short-Term Memory (LSTM) networks and Auto encoders (AE) (LSTM-AE-CC). This method incorporates a temporal modeling mechanism into the traditional CC framework, capturing temporal dependencies in CSI using LSTM and learning continuous latent representations with AE. The proposed method ensures both geometric consistency of the channel and explicit modeling of the time-varying properties. Experimental results demonstrate that the proposed method outperforms traditional CC methods in various real-world communication scenarios, particularly in terms of channel charting stability, trajectory continuity, and long-term predictability.

STARS: Shared-specific Translation and Alignment for missing-modality Remote Sensing Semantic Segmentation

Multimodal remote sensing technology significantly enhances the understanding of surface semantics by integrating heterogeneous data such as optical images, Synthetic Aperture Radar (SAR), and Digital Surface Models (DSM). However, in practical applications, the missing of modality data (e.g., optical or DSM) is a common and severe challenge, which leads to performance decline in traditional multimodal fusion models. Existing methods for addressing missing modalities still face limitations, including feature collapse and overly generalized recovered features. To address these issues, we propose \textbf{STARS} (\textbf{S}hared-specific \textbf{T}ranslation and \textbf{A}lignment for missing-modality \textbf{R}emote \textbf{S}ensing), a robust semantic segmentation framework for incomplete multimodal inputs. STARS is built on two key designs. First, we introduce an asymmetric alignment mechanism with bidirectional translation and stop-gradient, which effectively prevents feature collapse and reduces sensitivity to hyperparameters. Second, we propose a Pixel-level Semantic sampling Alignment (PSA) strategy that combines class-balanced pixel sampling with cross-modality semantic alignment loss, to mitigate alignment failures caused by severe class imbalance and improve minority-class recognition.

Risk-Averse Learning with Varying Risk Levels

In safety-critical decision-making, the environment may evolve over time, and the learner adjusts its risk level accordingly. This work investigates risk-averse online optimization in dynamic environments with varying risk levels, employing Conditional Value-at-Risk (CVaR) as the risk measure. To capture the dynamics of the environment and risk levels, we employ the function variation metric and introduce a novel risk-level variation metric. Two information settings are considered: a first-order scenario, where the learner observes both function values and their gradients; and a zeroth-order scenario, where only function evaluations are available. For both cases, we develop risk-averse learning algorithms with a limited sampling budget and analyze their dynamic regret bounds in terms of function variation, risk-level variation, and the total number of samples. The regret analysis demonstrates the adaptability of the algorithms in non-stationary and risk-sensitive settings. Finally, numerical experiments are presented to demonstrate the efficacy of the methods.

ManchuTTS: Towards High-Quality Manchu Speech Synthesis via Flow Matching and Hierarchical Text Representation

As an endangered language, Manchu presents unique challenges for speech synthesis, including severe data scarcity and strong phonological agglutination. This paper proposes ManchuTTS(Manchu Text to Speech), a novel approach tailored to Manchu's linguistic characteristics. To handle agglutination, this method designs a three-tier text representation (phoneme, syllable, prosodic) and a cross-modal hierarchical attention mechanism for multi-granular alignment. The synthesis model integrates deep convolutional networks with a flow-matching Transformer, enabling efficient, non-autoregressive generation. This method further introduce a hierarchical contrastive loss to guide structured acoustic-linguistic correspondence. To address low-resource constraints, This method construct the first Manchu TTS dataset and employ a data augmentation strategy. Experiments demonstrate that ManchuTTS attains a MOS of 4.52 using a 5.2-hour training subset derived from our full 6.24-hour annotated corpus, outperforming all baseline models by a notable margin. Ablations confirm hierarchical guidance improves agglutinative word pronunciation accuracy (AWPA) by 31% and prosodic naturalness by 27%.

SparScene: Efficient Traffic Scene Representation via Sparse Graph Learning for Large-Scale Trajectory Generation

Multi-agent trajectory generation is a core problem for autonomous driving and intelligent transportation systems. However, efficiently modeling the dynamic interactions between numerous road users and infrastructures in complex scenes remains an open problem. Existing methods typically employ distance-based or fully connected dense graph structures to capture interaction information, which not only introduces a large number of redundant edges but also requires complex and heavily parameterized networks for encoding, thereby resulting in low training and inference efficiency, limiting scalability to large and complex traffic scenes. To overcome the limitations of existing methods, we propose SparScene, a sparse graph learning framework designed for efficient and scalable traffic scene representation. Instead of relying on distance thresholds, SparScene leverages the lane graph topology to construct structure-aware sparse connections between agents and lanes, enabling efficient yet informative scene graph representation. SparScene adopts a lightweight graph encoder that efficiently aggregates agent-map and agent-agent interactions, yielding compact scene representations with substantially improved efficiency and scalability. On the motion prediction benchmark of the Waymo Open Motion Dataset (WOMD), SparScene achieves competitive performance with remarkable efficiency. It generates trajectories for more than 200 agents in a scene within 5 ms and scales to more than 5,000 agents and 17,000 lanes with merely 54 ms of inference time with a GPU memory of 2.9 GB, highlighting its superior scalability for large-scale traffic scenes.

Wasserstein Distributionally Robust Nash Equilibrium Seeking with Heterogeneous Data: A Lagrangian Approach

We study a class of distributionally robust games where agents are allowed to heterogeneously choose their risk aversion with respect to distributional shifts of the uncertainty. In our formulation, heterogeneous Wasserstein ball constraints on each distribution are enforced through a penalty function leveraging a Lagrangian formulation. We then formulate the distributionally robust Nash equilibrium problem and show that under certain assumptions it is equivalent to a finite-dimensional variational inequality problem with a strongly monotone mapping. We then design an approximate Nash equilibrium seeking algorithm and prove convergence of the average regret to a quantity that diminishes with the number of iterations, thus learning the desired equilibrium up to an a priori specified accuracy. Numerical simulations corroborate our theoretical findings.