refer to the report for detailed contributions
Abstract:Generalist pathology foundation models (PFMs), pretrained on large-scale multi-organ datasets, have demonstrated remarkable predictive capabilities across diverse clinical applications. However, their proficiency on the full spectrum of clinically essential tasks within a specific organ system remains an open question due to the lack of large-scale validation cohorts for a single organ as well as the absence of a tailored training paradigm that can effectively translate broad histomorphological knowledge into the organ-specific expertise required for specialist-level interpretation. In this study, we propose BRIGHT, the first PFM specifically designed for breast pathology, trained on approximately 210 million histopathology tiles from over 51,000 breast whole-slide images derived from a cohort of over 40,000 patients across 19 hospitals. BRIGHT employs a collaborative generalist-specialist framework to capture both universal and organ-specific features. To comprehensively evaluate the performance of PFMs on breast oncology, we curate the largest multi-institutional cohorts to date for downstream task development and evaluation, comprising over 25,000 WSIs across 10 hospitals. The validation cohorts cover the full spectrum of breast pathology across 24 distinct clinical tasks spanning diagnosis, biomarker prediction, treatment response and survival prediction. Extensive experiments demonstrate that BRIGHT outperforms three leading generalist PFMs, achieving state-of-the-art (SOTA) performance in 21 of 24 internal validation tasks and in 5 of 10 external validation tasks with excellent heatmap interpretability. By evaluating on large-scale validation cohorts, this study not only demonstrates BRIGHT's clinical utility in breast oncology but also validates a collaborative generalist-specialist paradigm, providing a scalable template for developing PFMs on a specific organ system.
Abstract:Low-altitude network is a key enabler for extending coverage and recovering connectivity in 6G systems, especially when terrestrial infrastructure is unavailable. This paper studies a uncrewed aerial vehicle (UAV)-mounted rotatable intelligent reflecting surface (IRS) as a low-altitude reflector between a blocked base station (BS) and a ground terminal (GT). Unlike the conventional isotropic-element assumption, each IRS element is modeled with a hemispherical directive radiation pattern, whose boresight can be adjusted via element rotations. We formulate a new optimization problem that jointly designs IRS phase shifts, per-element rotation vectors, and UAV placement to maximize the received signal-to-noise ratio (SNR). Leveraging the problem structure, we derive closed-form solutions for phase alignment and element rotations, showing that the optimal boresight points are along the internal angular bisector between the BS-IRS and GT-IRS directions. With these closed forms, the design reduces to a placement optimization problem over a box-constrained airspace; we solve it using an efficient projected gradient algorithm with majorization-minimization update and a global Lipschitz constant. Numerical results demonstrate substantial SNR gains from directive elements and reveal a fundamental trade-off between directional gain and path loss, yielding useful insights into low-altitude deployment of UAV-mounted IRSs.
Abstract:Reinforcement learning (RL) has demonstrated remarkable success in text and image generation, yet its potential in 3D generation remains largely unexplored. Existing attempts typically rely on offline direct preference optimization (DPO) method, which suffers from low training efficiency and limited generalization. In this work, we aim to enhance both the training efficiency and generation quality of RL in 3D mesh generation. Specifically, (1) we design the first asynchronous online RL framework tailored for 3D mesh generation post-training efficiency improvement, which is 3.75$\times$ faster than synchronous RL. (2) We propose Advantage-guided Ranking Preference Optimization (ARPO), a novel RL algorithm that achieves a better trade-off between training efficiency and generalization than current RL algorithms designed for 3D mesh generation, such as DPO and group relative policy optimization (GRPO). (3) Based on asynchronous ARPO, we propose Mesh-Pro, which additionally introduces a novel diagonal-aware mixed triangular-quadrilateral tokenization for mesh representation and a ray-based reward for geometric integrity. Mesh-Pro achieves state-of-the-art performance on artistic and dense meshes.
Abstract:Despite their impressive performance, self-supervised speech models often struggle to generalize to new languages and tend to forget previously acquired knowledge during continual training. To address this, we propose Lamer-SSL, a parameter-efficient framework that integrates a Layer-Aware MixturE of LoRA Experts (Lamer) module with a replay strategy. The Lamer module enables flexible balancing between shared and language-specific representations, while layer-aware expert allocation assigns more experts to deeper layers where semantic information is richer. Meanwhile, the replay strategy retains prior knowledge using minimal data, mitigating forgetting during continual training. Experiments on automatic speech recognition (ASR) and language identification (LID) demonstrate that Lamer-SSL extends self-supervised models to new languages effectively while maintaining strong performance on previously learned languages with only 2.14% parameters being trainable.
Abstract:Autoregressive models, often built on Transformer architectures, represent a powerful paradigm for generating ultra-long videos by synthesizing content in sequential chunks. However, this sequential generation process is notoriously slow. While caching strategies have proven effective for accelerating traditional video diffusion models, existing methods assume uniform denoising across all frames-an assumption that breaks down in autoregressive models where different video chunks exhibit varying similarity patterns at identical timesteps. In this paper, we present FlowCache, the first caching framework specifically designed for autoregressive video generation. Our key insight is that each video chunk should maintain independent caching policies, allowing fine-grained control over which chunks require recomputation at each timestep. We introduce a chunkwise caching strategy that dynamically adapts to the unique denoising characteristics of each chunk, complemented by a joint importance-redundancy optimized KV cache compression mechanism that maintains fixed memory bounds while preserving generation quality. Our method achieves remarkable speedups of 2.38 times on MAGI-1 and 6.7 times on SkyReels-V2, with negligible quality degradation (VBench: 0.87 increase and 0.79 decrease respectively). These results demonstrate that FlowCache successfully unlocks the potential of autoregressive models for real-time, ultra-long video generation-establishing a new benchmark for efficient video synthesis at scale. The code is available at https://github.com/mikeallen39/FlowCache.
Abstract:We introduce Kimi K2.5, an open-source multimodal agentic model designed to advance general agentic intelligence. K2.5 emphasizes the joint optimization of text and vision so that two modalities enhance each other. This includes a series of techniques such as joint text-vision pre-training, zero-vision SFT, and joint text-vision reinforcement learning. Building on this multimodal foundation, K2.5 introduces Agent Swarm, a self-directed parallel agent orchestration framework that dynamically decomposes complex tasks into heterogeneous sub-problems and executes them concurrently. Extensive evaluations show that Kimi K2.5 achieves state-of-the-art results across various domains including coding, vision, reasoning, and agentic tasks. Agent Swarm also reduces latency by up to $4.5\times$ over single-agent baselines. We release the post-trained Kimi K2.5 model checkpoint to facilitate future research and real-world applications of agentic intelligence.
Abstract:Ensuring safety, factuality and overall quality in the generations of large language models is a critical challenge, especially as these models are increasingly deployed in real-world applications. The prevailing approach to addressing these issues involves collecting expensive, carefully curated datasets and applying multiple stages of fine-tuning and alignment. However, even this complex pipeline cannot guarantee the correction of patterns learned during pretraining. Therefore, addressing these issues during pretraining is crucial, as it shapes a model's core behaviors and prevents unsafe or hallucinated outputs from becoming deeply embedded. To tackle this issue, we introduce a new pretraining method that streams documents and uses reinforcement learning (RL) to improve the next K generated tokens at each step. A strong, post-trained model judges candidate generations -- including model rollouts, the original suffix, and a rewritten suffix -- for quality, safety, and factuality. Early in training, the process relies on the original and rewritten suffixes; as the model improves, RL rewards high-quality rollouts. This approach builds higher quality, safer, and more factual models from the ground up. In experiments, our method gives 36.2% and 18.5% relative improvements over standard pretraining in terms of factuality and safety, and up to 86.3% win rate improvements in overall generation quality.
Abstract:Self-supervised learning (SSL) has greatly advanced speech representation learning, but multilingual SSL models remain constrained to languages encountered during pretraining. Retraining from scratch to incorporate new languages is computationally expensive, while sequential training without migitation strategies often leads to catastrophic forgetting. To address this, we propose MiLorE-SSL, a lightweight framework that combines LoRA modules with a soft mixture-of-experts (MoE) mechanism for efficient continual multilingual training. LoRA provides efficient low-rank adaptation, while soft MoE promotes flexible expert sharing across languages, reducing cross-lingual interference. To further mitigate forgetting, we introduce limited replay data from existing languages, avoiding reliance on large historical corpora. Experiments on ML-SUPERB demonstrate that MiLorE-SSL achieves strong performance in new languages and improves the ability in existing ones with only 2.14% trainable parameters.
Abstract:Although Large Language Models (LLMs) excel in many tasks, their application to Speech-to-Speech Translation (S2ST) is underexplored and hindered by data scarcity. To bridge this gap, we propose PROST-LLM (PROgressive Speech-to-speech Translation) to enhance the S2ST capabilities in LLMs progressively. First, we fine-tune the LLMs with the CVSS corpus, employing designed tri-task learning and chain of modality methods to boost the initial performance. Then, leveraging the fine-tuned model, we generate preference pairs through self-sampling and back-translation without human evaluation. Finally, these preference pairs are used for preference optimization to enhance the model's S2ST capability further. Extensive experiments confirm the effectiveness of our proposed PROST-LLM in improving the S2ST capability of LLMs.
Abstract:High-dimensional portfolio optimization faces significant computational challenges under complex constraints, with traditional optimization methods struggling to balance convergence speed and global exploration capability. To address this, firstly, we introduce an enhanced Sharpe ratio-based model that incorporates all constraints into the objective function using adaptive penalty terms, transforming the original constrained problem into an unconstrained single-objective formulation. This approach preserves financial interpretability while simplifying algorithmic implementation. To efficiently solve the resulting high-dimensional optimization problem, we propose a Quantum Hybrid Differential Evolution (QHDE) algorithm, which integrates Quantum-inspired probabilistic behavior into the standard DE framework. QHDE employs a Schrodinger-inspired probabilistic mechanism for population evolution, enabling more flexible and diversified solution updates. To further enhance performance, a good point set-chaos reverse learning strategy is adopted to generate a well-dispersed initial population, and a dynamic elite pool combined with Cauchy-Gaussian hybrid perturbations strengthens global exploration and mitigates premature convergence. Experimental validation on CEC benchmarks and real-world portfolios involving 20 to 80 assets demonstrates that QHDE's performance improves by up to 73.4%. It attains faster convergence, higher solution precision, and greater robustness than seven state-of-the-art counterparts, thereby confirming its suitability for complex, high-dimensional portfolio optimization and advancing quantum-inspired evolutionary research in computational finance.