Beyond the LUMIR challenge: The pathway to foundational registration models

Medical image challenges have played a transformative role in advancing the field, catalyzing algorithmic innovation and establishing new performance standards across diverse clinical applications. Image registration, a foundational task in neuroimaging pipelines, has similarly benefited from the Learn2Reg initiative. Building on this foundation, we introduce the Large-scale Unsupervised Brain MRI Image Registration (LUMIR) challenge, a next-generation benchmark designed to assess and advance unsupervised brain MRI registration. Distinct from prior challenges that leveraged anatomical label maps for supervision, LUMIR removes this dependency by providing over 4,000 preprocessed T1-weighted brain MRIs for training without any label maps, encouraging biologically plausible deformation modeling through self-supervision. In addition to evaluating performance on 590 held-out test subjects, LUMIR introduces a rigorous suite of zero-shot generalization tasks, spanning out-of-domain imaging modalities (e.g., FLAIR, T2-weighted, T2*-weighted), disease populations (e.g., Alzheimer's disease), acquisition protocols (e.g., 9.4T MRI), and species (e.g., macaque brains). A total of 1,158 subjects and over 4,000 image pairs were included for evaluation. Performance was assessed using both segmentation-based metrics (Dice coefficient, 95th percentile Hausdorff distance) and landmark-based registration accuracy (target registration error). Across both in-domain and zero-shot tasks, deep learning-based methods consistently achieved state-of-the-art accuracy while producing anatomically plausible deformation fields. The top-performing deep learning-based models demonstrated diffeomorphic properties and inverse consistency, outperforming several leading optimization-based methods, and showing strong robustness to most domain shifts, the exception being a drop in performance on out-of-domain contrasts.

Depth Pro: Sharp Monocular Metric Depth in Less Than a Second

We present a foundation model for zero-shot metric monocular depth estimation. Our model, Depth Pro, synthesizes high-resolution depth maps with unparalleled sharpness and high-frequency details. The predictions are metric, with absolute scale, without relying on the availability of metadata such as camera intrinsics. And the model is fast, producing a 2.25-megapixel depth map in 0.3 seconds on a standard GPU. These characteristics are enabled by a number of technical contributions, including an efficient multi-scale vision transformer for dense prediction, a training protocol that combines real and synthetic datasets to achieve high metric accuracy alongside fine boundary tracing, dedicated evaluation metrics for boundary accuracy in estimated depth maps, and state-of-the-art focal length estimation from a single image. Extensive experiments analyze specific design choices and demonstrate that Depth Pro outperforms prior work along multiple dimensions. We release code and weights at https://github.com/apple/ml-depth-pro

Enhancing Incremental Summarization with Structured Representations

Large language models (LLMs) often struggle with processing extensive input contexts, which can lead to redundant, inaccurate, or incoherent summaries. Recent methods have used unstructured memory to incrementally process these contexts, but they still suffer from information overload due to the volume of unstructured data handled. In our study, we introduce structured knowledge representations ($GU_{json}$), which significantly improve summarization performance by 40% and 14% across two public datasets. Most notably, we propose the Chain-of-Key strategy ($CoK_{json}$) that dynamically updates or augments these representations with new information, rather than recreating the structured memory for each new source. This method further enhances performance by 7% and 4% on the datasets.

SUMIE: A Synthetic Benchmark for Incremental Entity Summarization

No existing dataset adequately tests how well language models can incrementally update entity summaries - a crucial ability as these models rapidly advance. The Incremental Entity Summarization (IES) task is vital for maintaining accurate, up-to-date knowledge. To address this, we introduce SUMIE, a fully synthetic dataset designed to expose real-world IES challenges. This dataset effectively highlights problems like incorrect entity association and incomplete information presentation. Unlike common synthetic datasets, ours captures the complexity and nuances found in real-world data. We generate informative and diverse attributes, summaries, and unstructured paragraphs in sequence, ensuring high quality. The alignment between generated summaries and paragraphs exceeds 96%, confirming the dataset's quality. Extensive experiments demonstrate the dataset's difficulty - state-of-the-art LLMs struggle to update summaries with an F1 higher than 80.4%. We will open source the benchmark and the evaluation metrics to help the community make progress on IES tasks.

STRUM-LLM: Attributed and Structured Contrastive Summarization

Users often struggle with decision-making between two options (A vs B), as it usually requires time-consuming research across multiple web pages. We propose STRUM-LLM that addresses this challenge by generating attributed, structured, and helpful contrastive summaries that highlight key differences between the two options. STRUM-LLM identifies helpful contrast: the specific attributes along which the two options differ significantly and which are most likely to influence the user's decision. Our technique is domain-agnostic, and does not require any human-labeled data or fixed attribute list as supervision. STRUM-LLM attributes all extractions back to the input sources along with textual evidence, and it does not have a limit on the length of input sources that it can process. STRUM-LLM Distilled has 100x more throughput than the models with comparable performance while being 10x smaller. In this paper, we provide extensive evaluations for our method and lay out future directions for our currently deployed system.

Adaptive Integration of Partial Label Learning and Negative Learning for Enhanced Noisy Label Learning

There has been significant attention devoted to the effectiveness of various domains, such as semi-supervised learning, contrastive learning, and meta-learning, in enhancing the performance of methods for noisy label learning (NLL) tasks. However, most existing methods still depend on prior assumptions regarding clean samples amidst different sources of noise (\eg, a pre-defined drop rate or a small subset of clean samples). In this paper, we propose a simple yet powerful idea called \textbf{NPN}, which revolutionizes \textbf{N}oisy label learning by integrating \textbf{P}artial label learning (PLL) and \textbf{N}egative learning (NL). Toward this goal, we initially decompose the given label space adaptively into the candidate and complementary labels, thereby establishing the conditions for PLL and NL. We propose two adaptive data-driven paradigms of label disambiguation for PLL: hard disambiguation and soft disambiguation. Furthermore, we generate reliable complementary labels using all non-candidate labels for NL to enhance model robustness through indirect supervision. To maintain label reliability during the later stage of model training, we introduce a consistency regularization term that encourages agreement between the outputs of multiple augmentations. Experiments conducted on both synthetically corrupted and real-world noisy datasets demonstrate the superiority of NPN compared to other state-of-the-art (SOTA) methods. The source code has been made available at {\color{purple}{\url{https://github.com/NUST-Machine-Intelligence-Laboratory/NPN}}}.

FaceStudio: Put Your Face Everywhere in Seconds

This study investigates identity-preserving image synthesis, an intriguing task in image generation that seeks to maintain a subject's identity while adding a personalized, stylistic touch. Traditional methods, such as Textual Inversion and DreamBooth, have made strides in custom image creation, but they come with significant drawbacks. These include the need for extensive resources and time for fine-tuning, as well as the requirement for multiple reference images. To overcome these challenges, our research introduces a novel approach to identity-preserving synthesis, with a particular focus on human images. Our model leverages a direct feed-forward mechanism, circumventing the need for intensive fine-tuning, thereby facilitating quick and efficient image generation. Central to our innovation is a hybrid guidance framework, which combines stylized images, facial images, and textual prompts to guide the image generation process. This unique combination enables our model to produce a variety of applications, such as artistic portraits and identity-blended images. Our experimental results, including both qualitative and quantitative evaluations, demonstrate the superiority of our method over existing baseline models and previous works, particularly in its remarkable efficiency and ability to preserve the subject's identity with high fidelity.

An Augmentation Strategy for Visually Rich Documents

Many business workflows require extracting important fields from form-like documents (e.g. bank statements, bills of lading, purchase orders, etc.). Recent techniques for automating this task work well only when trained with large datasets. In this work we propose a novel data augmentation technique to improve performance when training data is scarce, e.g. 10-250 documents. Our technique, which we call FieldSwap, works by swapping out the key phrases of a source field with the key phrases of a target field to generate new synthetic examples of the target field for use in training. We demonstrate that this approach can yield 1-7 F1 point improvements in extraction performance.

A Benchmark for Structured Extractions from Complex Documents

Understanding visually-rich business documents to extract structured data and automate business workflows has been receiving attention both in academia and industry. Although recent multi-modal language models have achieved impressive results, we find that existing benchmarks do not reflect the complexity of real documents seen in industry. In this work, we identify the desiderata for a more comprehensive benchmark and propose one we call Visually Rich Document Understanding (VRDU). VRDU contains two datasets that represent several challenges: rich schema including diverse data types as well as nested entities, complex templates including tables and multi-column layouts, and diversity of different layouts (templates) within a single document type. We design few-shot and conventional experiment settings along with a carefully designed matching algorithm to evaluate extraction results. We report the performance of strong baselines and three observations: (1) generalizing to new document templates is very challenging, (2) few-shot performance has a lot of headroom, and (3) models struggle with nested fields such as line-items in an invoice. We plan to open source the benchmark and the evaluation toolkit. We hope this helps the community make progress on these challenging tasks in extracting structured data from visually rich documents.

Radically Lower Data-Labeling Costs for Visually Rich Document Extraction Models

A key bottleneck in building automatic extraction models for visually rich documents like invoices is the cost of acquiring the several thousand high-quality labeled documents that are needed to train a model with acceptable accuracy. We propose Selective Labeling to simplify the labeling task to provide "yes/no" labels for candidate extractions predicted by a model trained on partially labeled documents. We combine this with a custom active learning strategy to find the predictions that the model is most uncertain about. We show through experiments on document types drawn from 3 different domains that selective labeling can reduce the cost of acquiring labeled data by $10\times$ with a negligible loss in accuracy.