From Evidence-Based Medicine to Knowledge Graph: Retrieval-Augmented Generation for Sports Rehabilitation and a Domain Benchmark

In medicine, large language models (LLMs) increasingly rely on retrieval-augmented generation (RAG) to ground outputs in up-to-date external evidence. However, current RAG approaches focus primarily on performance improvements while overlooking evidence-based medicine (EBM) principles. This study addresses two key gaps: (1) the lack of PICO alignment between queries and retrieved evidence, and (2) the absence of evidence hierarchy considerations during reranking. We present a generalizable strategy for adapting EBM to graph-based RAG, integrating the PICO framework into knowledge graph construction and retrieval, and proposing a Bayesian-inspired reranking algorithm to calibrate ranking scores by evidence grade without introducing predefined weights. We validated this framework in sports rehabilitation, a literature-rich domain currently lacking RAG systems and benchmarks. We released a knowledge graph (357,844 nodes and 371,226 edges) and a reusable benchmark of 1,637 QA pairs. The system achieved 0.830 nugget coverage, 0.819 answer faithfulness, 0.882 semantic similarity, and 0.788 PICOT match accuracy. In a 5-point Likert evaluation, five expert clinicians rated the system 4.66-4.84 across factual accuracy, faithfulness, relevance, safety, and PICO alignment. These findings demonstrate that the proposed EBM adaptation strategy improves retrieval and answer quality and is transferable to other clinical domains. The released resources also help address the scarcity of RAG datasets in sports rehabilitation.

Cross-modal Context-aware Learning for Visual Prompt Guided Multimodal Image Understanding in Remote Sensing

Recent advances in image understanding have enabled methods that leverage large language models for multimodal reasoning in remote sensing. However, existing approaches still struggle to steer models to the user-relevant regions when only simple, generic text prompts are available. Moreover, in large-scale aerial imagery many objects exhibit highly similar visual appearances and carry rich inter-object relationships, which further complicates accurate recognition. To address these challenges, we propose Cross-modal Context-aware Learning for Visual Prompt-Guided Multimodal Image Understanding (CLV-Net). CLV-Net lets users supply a simple visual cue, a bounding box, to indicate a region of interest, and uses that cue to guide the model to generate correlated segmentation masks and captions that faithfully reflect user intent. Central to our design is a Context-Aware Mask Decoder that models and integrates inter-object relationships to strengthen target representations and improve mask quality. In addition, we introduce a Semantic and Relationship Alignment module: a Cross-modal Semantic Consistency Loss enhances fine-grained discrimination among visually similar targets, while a Relationship Consistency Loss enforces alignment between textual relations and visual interactions. Comprehensive experiments on two benchmark datasets show that CLV-Net outperforms existing methods and establishes new state-of-the-art results. The model effectively captures user intent and produces precise, intention-aligned multimodal outputs.

Non-Linear Trajectory Modeling for Multi-Step Gradient Inversion Attacks in Federated Learning

Federated Learning (FL) preserves privacy by keeping raw data local, yet Gradient Inversion Attacks (GIAs) pose significant threats. In FedAVG multi-step scenarios, attackers observe only aggregated gradients, making data reconstruction challenging. Existing surrogate model methods like SME assume linear parameter trajectories, but we demonstrate this severely underestimates SGD's nonlinear complexity, fundamentally limiting attack effectiveness. We propose Non-Linear Surrogate Model Extension (NL-SME), the first method to introduce nonlinear parametric trajectory modeling for GIAs. Our approach replaces linear interpolation with learnable quadratic B\'ezier curves that capture SGD's curved characteristics through control points, combined with regularization and dvec scaling mechanisms for enhanced expressiveness. Extensive experiments on CIFAR-100 and FEMNIST datasets show NL-SME significantly outperforms baselines across all metrics, achieving order-of-magnitude improvements in cosine similarity loss while maintaining computational efficiency.This work exposes heightened privacy vulnerabilities in FL's multi-step update paradigm and offers novel perspectives for developing robust defense strategies.

United Minds or Isolated Agents? Exploring Coordination of LLMs under Cognitive Load Theory

Large Language Models (LLMs) exhibit a notable performance ceiling on complex, multi-faceted tasks, as they often fail to integrate diverse information or adhere to multiple constraints. We posit that such limitation arises when the demands of a task exceed the LLM's effective cognitive load capacity. This interpretation draws a strong analogy to Cognitive Load Theory (CLT) in cognitive science, which explains similar performance boundaries in the human mind, and is further supported by emerging evidence that reveals LLMs have bounded working memory characteristics. Building upon this CLT-grounded understanding, we introduce CoThinker, a novel LLM-based multi-agent framework designed to mitigate cognitive overload and enhance collaborative problem-solving abilities. CoThinker operationalizes CLT principles by distributing intrinsic cognitive load through agent specialization and managing transactional load via structured communication and a collective working memory. We empirically validate CoThinker on complex problem-solving tasks and fabricated high cognitive load scenarios, demonstrating improvements over existing multi-agent baselines in solution quality and efficiency. Our analysis reveals characteristic interaction patterns, providing insights into the emergence of collective cognition and effective load management, thus offering a principled approach to overcoming LLM performance ceilings.

RTime-QA: A Benchmark for Atomic Temporal Event Understanding in Large Multi-modal Models

Understanding accurate atomic temporal event is essential for video comprehension. However, current video-language benchmarks often fall short to evaluate Large Multi-modal Models' (LMMs) temporal event understanding capabilities, as they can be effectively addressed using image-language models. In this paper, we introduce RTime-QA, a novel benchmark specifically designed to assess the atomic temporal event understanding ability of LMMs. RTime-QA comprises 822 high-quality, carefully-curated video-text questions, each meticulously annotated by human experts. Each question features a video depicting an atomic temporal event, paired with both correct answers and temporal negative descriptions, specifically designed to evaluate temporal understanding. To advance LMMs' temporal event understanding ability, we further introduce RTime-IT, a 14k instruction-tuning dataset that employs a similar annotation process as RTime-QA. Extensive experimental analysis demonstrates that RTime-QA presents a significant challenge for LMMs: the state-of-the-art model Qwen2-VL achieves only 34.6 on strict-ACC metric, substantially lagging behind human performance. Furthermore, our experiments reveal that RTime-IT effectively enhance LMMs' capacity in temporal understanding. By fine-tuning on RTime-IT, our Qwen2-VL achieves 65.9 on RTime-QA.

Adams Bashforth Moulton Solver for Inversion and Editing in Rectified Flow

Rectified flow models have achieved remarkable performance in image and video generation tasks. However, existing numerical solvers face a trade-off between fast sampling and high-accuracy solutions, limiting their effectiveness in downstream applications such as reconstruction and editing. To address this challenge, we propose leveraging the Adams-Bashforth-Moulton (ABM) predictor-corrector method to enhance the accuracy of ODE solving in rectified flow models. Specifically, we introduce ABM-Solver, which integrates a multi step predictor corrector approach to reduce local truncation errors and employs Adaptive Step Size Adjustment to improve sampling speed. Furthermore, to effectively preserve non edited regions while facilitating semantic modifications, we introduce a Mask Guided Feature Injection module. We estimate self-similarity to generate a spatial mask that differentiates preserved regions from those available for editing. Extensive experiments on multiple high-resolution image datasets validate that ABM-Solver significantly improves inversion precision and editing quality, outperforming existing solvers without requiring additional training or optimization.

Multi-Class Segmentation of Aortic Branches and Zones in Computed Tomography Angiography: The AortaSeg24 Challenge

Multi-class segmentation of the aorta in computed tomography angiography (CTA) scans is essential for diagnosing and planning complex endovascular treatments for patients with aortic dissections. However, existing methods reduce aortic segmentation to a binary problem, limiting their ability to measure diameters across different branches and zones. Furthermore, no open-source dataset is currently available to support the development of multi-class aortic segmentation methods. To address this gap, we organized the AortaSeg24 MICCAI Challenge, introducing the first dataset of 100 CTA volumes annotated for 23 clinically relevant aortic branches and zones. This dataset was designed to facilitate both model development and validation. The challenge attracted 121 teams worldwide, with participants leveraging state-of-the-art frameworks such as nnU-Net and exploring novel techniques, including cascaded models, data augmentation strategies, and custom loss functions. We evaluated the submitted algorithms using the Dice Similarity Coefficient (DSC) and Normalized Surface Distance (NSD), highlighting the approaches adopted by the top five performing teams. This paper presents the challenge design, dataset details, evaluation metrics, and an in-depth analysis of the top-performing algorithms. The annotated dataset, evaluation code, and implementations of the leading methods are publicly available to support further research. All resources can be accessed at https://aortaseg24.grand-challenge.org.

Enhancing Cluster Resilience: LLM-agent Based Autonomous Intelligent Cluster Diagnosis System and Evaluation Framework

Recent advancements in Large Language Models (LLMs) and related technologies such as Retrieval-Augmented Generation (RAG) and Diagram of Thought (DoT) have enabled the creation of autonomous intelligent systems capable of performing cluster diagnostics and troubleshooting. By integrating these technologies with self-play methodologies, we have developed an LLM-agent system designed to autonomously diagnose and resolve issues within AI clusters. Our innovations include a knowledge base tailored for cluster diagnostics, enhanced LLM algorithms, practical deployment strategies for agents, and a benchmark specifically designed for evaluating LLM capabilities in this domain. Through extensive experimentation across multiple dimensions, we have demonstrated the superiority of our system in addressing the challenges faced in cluster diagnostics, particularly in detecting and rectifying performance issues more efficiently and accurately than traditional methods.

Identifying Influential nodes in Brain Networks via Self-Supervised Graph-Transformer

Studying influential nodes (I-nodes) in brain networks is of great significance in the field of brain imaging. Most existing studies consider brain connectivity hubs as I-nodes. However, this approach relies heavily on prior knowledge from graph theory, which may overlook the intrinsic characteristics of the brain network, especially when its architecture is not fully understood. In contrast, self-supervised deep learning can learn meaningful representations directly from the data. This approach enables the exploration of I-nodes for brain networks, which is also lacking in current studies. This paper proposes a Self-Supervised Graph Reconstruction framework based on Graph-Transformer (SSGR-GT) to identify I-nodes, which has three main characteristics. First, as a self-supervised model, SSGR-GT extracts the importance of brain nodes to the reconstruction. Second, SSGR-GT uses Graph-Transformer, which is well-suited for extracting features from brain graphs, combining both local and global characteristics. Third, multimodal analysis of I-nodes uses graph-based fusion technology, combining functional and structural brain information. The I-nodes we obtained are distributed in critical areas such as the superior frontal lobe, lateral parietal lobe, and lateral occipital lobe, with a total of 56 identified across different experiments. These I-nodes are involved in more brain networks than other regions, have longer fiber connections, and occupy more central positions in structural connectivity. They also exhibit strong connectivity and high node efficiency in both functional and structural networks. Furthermore, there is a significant overlap between the I-nodes and both the structural and functional rich-club. These findings enhance our understanding of the I-nodes within the brain network, and provide new insights for future research in further understanding the brain working mechanisms.

Gradient Diffusion: A Perturbation-Resilient Gradient Leakage Attack

Recent years have witnessed the vulnerability of Federated Learning (FL) against gradient leakage attacks, where the private training data can be recovered from the exchanged gradients, making gradient protection a critical issue for the FL training process. Existing solutions often resort to perturbation-based mechanisms, such as differential privacy, where each participating client injects a specific amount of noise into local gradients before aggregating to the server, and the global distribution variation finally conceals the gradient privacy. However, perturbation is not always the panacea for gradient protection since the robustness heavily relies on the injected noise. This intuition raises an interesting question: \textit{is it possible to deactivate existing protection mechanisms by removing the perturbation inside the gradients?} In this paper, we present the answer: \textit{yes} and propose the Perturbation-resilient Gradient Leakage Attack (PGLA), the first attempt to recover the perturbed gradients, without additional access to the original model structure or third-party data. Specifically, we leverage the inherent diffusion property of gradient perturbation protection and construct a novel diffusion-based denoising model to implement PGLA. Our insight is that capturing the disturbance level of perturbation during the diffusion reverse process can release the gradient denoising capability, which promotes the diffusion model to generate approximate gradients as the original clean version through adaptive sampling steps. Extensive experiments demonstrate that PGLA effectively recovers the protected gradients and exposes the FL training process to the threat of gradient leakage, achieving the best quality in gradient denoising and data recovery compared to existing models. We hope to arouse public attention on PGLA and its defense.