Infi-Med: Low-Resource Medical MLLMs with Robust Reasoning Evaluation

Multimodal large language models (MLLMs) have demonstrated promising prospects in healthcare, particularly for addressing complex medical tasks, supporting multidisciplinary treatment (MDT), and enabling personalized precision medicine. However, their practical deployment faces critical challenges in resource efficiency, diagnostic accuracy, clinical considerations, and ethical privacy. To address these limitations, we propose Infi-Med, a comprehensive framework for medical MLLMs that introduces three key innovations: (1) a resource-efficient approach through curating and constructing high-quality supervised fine-tuning (SFT) datasets with minimal sample requirements, with a forward-looking design that extends to both pretraining and posttraining phases; (2) enhanced multimodal reasoning capabilities for cross-modal integration and clinical task understanding; and (3) a systematic evaluation system that assesses model performance across medical modalities and task types. Our experiments demonstrate that Infi-Med achieves state-of-the-art (SOTA) performance in general medical reasoning while maintaining rapid adaptability to clinical scenarios. The framework establishes a solid foundation for deploying MLLMs in real-world healthcare settings by balancing model effectiveness with operational constraints.

ELDeR: Getting Efficient LLMs through Data-Driven Regularized Layer-wise Pruning

The deployment of Large language models (LLMs) in many fields is largely hindered by their high computational and memory costs. Recent studies suggest that LLMs exhibit sparsity, which can be used for pruning. Previous pruning methods typically follow a prune-then-finetune paradigm. Since the pruned parts still contain valuable information, statically removing them without updating the remaining parameters often results in irreversible performance degradation, requiring costly recovery fine-tuning (RFT) to maintain performance. To address this, we propose a novel paradigm: first apply regularization, then prune. Based on this paradigm, we propose ELDeR: Getting Efficient LLMs through Data-Driven Regularized Layer-wise Pruning. We multiply the output of each transformer layer by an initial weight, then we iteratively learn the weights of each transformer layer by using a small amount of data in a simple way. After that, we apply regularization to the difference between the output and input of the layers with smaller weights, forcing the information to be transferred to the remaining layers. Compared with direct pruning, ELDeR reduces the information loss caused by direct parameter removal, thus better preserving the model's language modeling ability. Experimental results show that ELDeR achieves superior performance compared with powerful layer-wise structured pruning methods, while greatly reducing RFT computational costs. Since ELDeR is a layer-wise pruning method, its end-to-end acceleration effect is obvious, making it a promising technique for efficient LLMs.

UTTG_ A Universal Teleoperation Approach via Online Trajectory Generation

Teleoperation is crucial for hazardous environment operations and serves as a key tool for collecting expert demonstrations in robot learning. However, existing methods face robotic hardware dependency and control frequency mismatches between teleoperation devices and robotic platforms. Our approach automatically extracts kinematic parameters from unified robot description format (URDF) files, and enables pluggable deployment across diverse robots through uniform interfaces. The proposed interpolation algorithm bridges the frequency gap between low-rate human inputs and high-frequency robotic control commands through online continuous trajectory generation, \n{while requiring no access to the closed, bottom-level control loop}. To enhance trajectory smoothness, we introduce a minimum-stretch spline that optimizes the motion quality. The system further provides precision and rapid modes to accommodate different task requirements. Experiments across various robotic platforms including dual-arm ones demonstrate generality and smooth operation performance of our methods. The code is developed in C++ with python interface, and available at https://github.com/IRMV-Manipulation-Group/UTTG.

NTIRE 2025 Challenge on Day and Night Raindrop Removal for Dual-Focused Images: Methods and Results

This paper reviews the NTIRE 2025 Challenge on Day and Night Raindrop Removal for Dual-Focused Images. This challenge received a wide range of impressive solutions, which are developed and evaluated using our collected real-world Raindrop Clarity dataset. Unlike existing deraining datasets, our Raindrop Clarity dataset is more diverse and challenging in degradation types and contents, which includes day raindrop-focused, day background-focused, night raindrop-focused, and night background-focused degradations. This dataset is divided into three subsets for competition: 14,139 images for training, 240 images for validation, and 731 images for testing. The primary objective of this challenge is to establish a new and powerful benchmark for the task of removing raindrops under varying lighting and focus conditions. There are a total of 361 participants in the competition, and 32 teams submitting valid solutions and fact sheets for the final testing phase. These submissions achieved state-of-the-art (SOTA) performance on the Raindrop Clarity dataset. The project can be found at https://lixinustc.github.io/CVPR-NTIRE2025-RainDrop-Competition.github.io/.

1-Tb/s/λ Transmission over Record 10714-km AR-HCF

We present the first single-channel 1.001-Tb/s DP-36QAM-PCS recirculating transmission over 73 loops of 146.77-km ultra-low-loss & low-IMI DNANF-5 fiber, achieving a record transmission distance of 10,714.28 km.

Representation Learning, Large-Scale 3D Molecular Pretraining, Molecular Property

Molecular pretrained representations (MPR) has emerged as a powerful approach for addressing the challenge of limited supervised data in applications such as drug discovery and material design. While early MPR methods relied on 1D sequences and 2D graphs, recent advancements have incorporated 3D conformational information to capture rich atomic interactions. However, these prior models treat molecules merely as discrete atom sets, overlooking the space surrounding them. We argue from a physical perspective that only modeling these discrete points is insufficient. We first present a simple yet insightful observation: naively adding randomly sampled virtual points beyond atoms can surprisingly enhance MPR performance. In light of this, we propose a principled framework that incorporates the entire 3D space spanned by molecules. We implement the framework via a novel Transformer-based architecture, dubbed SpaceFormer, with three key components: (1) grid-based space discretization; (2) grid sampling/merging; and (3) efficient 3D positional encoding. Extensive experiments show that SpaceFormer significantly outperforms previous 3D MPR models across various downstream tasks with limited data, validating the benefit of leveraging the additional 3D space beyond atoms in MPR models.

"My Grade is Wrong!": A Contestable AI Framework for Interactive Feedback in Evaluating Student Essays

Interactive feedback, where feedback flows in both directions between teacher and student, is more effective than traditional one-way feedback. However, it is often too time-consuming for widespread use in educational practice. While Large Language Models (LLMs) have potential for automating feedback, they struggle with reasoning and interaction in an interactive setting. This paper introduces CAELF, a Contestable AI Empowered LLM Framework for automating interactive feedback. CAELF allows students to query, challenge, and clarify their feedback by integrating a multi-agent system with computational argumentation. Essays are first assessed by multiple Teaching-Assistant Agents (TA Agents), and then a Teacher Agent aggregates the evaluations through formal reasoning to generate feedback and grades. Students can further engage with the feedback to refine their understanding. A case study on 500 critical thinking essays with user studies demonstrates that CAELF significantly improves interactive feedback, enhancing the reasoning and interaction capabilities of LLMs. This approach offers a promising solution to overcoming the time and resource barriers that have limited the adoption of interactive feedback in educational settings.

pFLFE: Cross-silo Personalized Federated Learning via Feature Enhancement on Medical Image Segmentation

In medical image segmentation, personalized cross-silo federated learning (FL) is becoming popular for utilizing varied data across healthcare settings to overcome data scarcity and privacy concerns. However, existing methods often suffer from client drift, leading to inconsistent performance and delayed training. We propose a new framework, Personalized Federated Learning via Feature Enhancement (pFLFE), designed to mitigate these challenges. pFLFE consists of two main stages: feature enhancement and supervised learning. The first stage improves differentiation between foreground and background features, and the second uses these enhanced features for learning from segmentation masks. We also design an alternative training approach that requires fewer communication rounds without compromising segmentation quality, even with limited communication resources. Through experiments on three medical segmentation tasks, we demonstrate that pFLFE outperforms the state-of-the-art methods.

Self-Consistency Training for Hamiltonian Prediction

Hamiltonian prediction is a versatile formulation to leverage machine learning for solving molecular science problems. Yet, its applicability is limited by insufficient labeled data for training. In this work, we highlight that Hamiltonian prediction possesses a self-consistency principle, based on which we propose an exact training method that does not require labeled data. This merit addresses the data scarcity difficulty, and distinguishes the task from other property prediction formulations with unique benefits: (1) self-consistency training enables the model to be trained on a large amount of unlabeled data, hence substantially enhances generalization; (2) self-consistency training is more efficient than labeling data with DFT for supervised training, since it is an amortization of DFT calculation over a set of molecular structures. We empirically demonstrate the better generalization in data-scarce and out-of-distribution scenarios, and the better efficiency from the amortization. These benefits push forward the applicability of Hamiltonian prediction to an ever larger scale.

End-to-End Crystal Structure Prediction from Powder X-Ray Diffraction

Powder X-ray diffraction (PXRD) is a crucial means for crystal structure determination. Such determination often involves external database matching to find a structural analogue and Rietveld refinement to obtain finer structure. However, databases may be incomplete and Rietveld refinement often requires intensive trial-and-error efforts from trained experimentalists, which remains ineffective in practice. To settle these issues, we propose XtalNet, the first end-to-end deep learning-based framework capable of ab initio generation of crystal structures that accurately match given PXRD patterns. The model employs contrastive learning and Diffusion-based conditional generation to enable the simultaneous execution of two tasks: crystal structure retrieval based on PXRD patterns and conditional structure generations. To validate the effectiveness of XtalNet, we curate a much more challenging and practical dataset hMOF-100, XtalNet performs well on this dataset, reaching 96.3\% top-10 hit ratio on the database retrieval task and 95.0\% top-10 match rate on the ranked structure generation task.